{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:59:32Z","timestamp":1791489572388,"version":"4.3.4"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["VIR\/25\/2011\/ECD-I"],"award-info":[{"award-number":["VIR\/25\/2011\/ECD-I"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Virology"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.jcv.2021.104970","type":"journal-article","created":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T11:49:41Z","timestamp":1631620181000},"page":"104970","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Childhood encephalitis hospitalizations associated with virus agents in medium-endemic states in India"],"prefix":"10.1016","volume":"144","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0468-4879","authenticated-orcid":false,"given":"Babasaheb V.","family":"Tandale","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay P.","family":"Bondre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gajanan N.","family":"Sapkal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varanasi","family":"Gopalkrishna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogesh K.","family":"Gurav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Kondal","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohiuddin S.","family":"Qazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9973-5311","authenticated-orcid":false,"given":"Rahul","family":"Narang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay Kumar","family":"Guduru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhimanyu K.","family":"Niswade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcv.2021.104970_bib0001","unstructured":"World health organisation (2019). Japanese encephalitis fact sheet. Available at https:\/\/www.who.int\/en\/news-room\/fact-sheets\/detail\/japanese-encephalitis. Accessed 5 March 2021."},{"key":"10.1016\/j.jcv.2021.104970_bib0002","unstructured":"World health organisation (2018). Vaccine preventable disease surveillance standards for JE 2018, Available at https:\/\/www.who.int\/immunization\/monitoring_surveillance\/burden\/vpd\/WHO_SurveillanceVaccinePreventable_10_JE_R2.pdf?ua=1. Accessed 5 March 2021."},{"key":"10.1016\/j.jcv.2021.104970_bib0003","unstructured":"World health organization regional office for south-east Asia.(2015). Prevention and Control of Japanese encephalitis (JE). Available at https:\/\/apps.who.int\/iris\/handle\/10665\/172432. Accessed 5 March 2021."},{"issue":"10","key":"10.1016\/j.jcv.2021.104970_bib0004","doi-asserted-by":"crossref","first-page":"766","DOI":"10.2471\/BLT.10.085233","article-title":"Estimated global incidence of Japanese encephalitis: a systematic review","volume":"89","author":"Campbell","year":"2011","journal-title":"Bull. World Health Organ"},{"issue":"3","key":"10.1016\/j.jcv.2021.104970_bib0005","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1212\/CPJ.0000000000000036","article-title":"Diagnosis and management of acute encephalitis: a practical approach","volume":"4","author":"Venkatesan","year":"2014","journal-title":"Neurol. Clin. Pract"},{"issue":"8","key":"10.1016\/j.jcv.2021.104970_bib0006","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1093\/cid\/cit458","article-title":"International encephalitis consortium. Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium","volume":"57","author":"Venkatesan","year":"2013","journal-title":"Clin. Infect. Dis"},{"issue":"1","key":"10.1016\/j.jcv.2021.104970_bib0007","first-page":"35","article-title":"Acute encephalitis syndrome in India: complexity of the problem","volume":"46","author":"Gore","year":"2014","journal-title":"J. Commun. Dis."},{"key":"10.1016\/j.jcv.2021.104970_bib0008","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0140-6736(04)16982-1","article-title":"A large outbreak of acute encephalitis with high case fatality rate in children in Andhra Pradesh, India in 2003 associated with Chandipura virus","volume":"364","author":"Rao","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jcv.2021.104970_bib0009","first-page":"395","article-title":"Chandipura virus encephalitis outbreak among children in Nagpur division, Maharashtra, 2007","volume":"132","author":"Gurav","year":"2010","journal-title":"Indian J. Med. Res"},{"issue":"3","key":"10.1016\/j.jcv.2021.104970_bib0010","doi-asserted-by":"crossref","first-page":"566","DOI":"10.4269\/ajtmh.2005.73.566","article-title":"An outbreak of Chandipura virus encephalitis in the eastern districts of Gujarat state, India","volume":"73","author":"Chadha","year":"2005","journal-title":"Am. J. Trop. Med. Hyg"},{"issue":"1","key":"10.1016\/j.jcv.2021.104970_bib0011","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/jmv.21041","article-title":"Chandipura virus: a major cause of acute encephalitis in children in North Telangana, Andhra Pradesh, India","volume":"80","author":"Tandale","year":"2008","journal-title":"J. Med. Virol"},{"issue":"2","key":"10.1016\/j.jcv.2021.104970_bib0012","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jcv.2009.06.027","article-title":"Systemic involvements and fatalities during Chikungunya epidemic in India, 2006","volume":"46","author":"Tandale","year":"2009","journal-title":"J. Clin. Virol"},{"key":"10.1016\/j.jcv.2021.104970_bib0013","unstructured":"Directorate, National Vector Borne Disease Control Programme, Government of India (2014). Operational guidelines for prevention and control of Japanese encephalitis\/acute encephalitis syndrome: Available at https:\/\/nvbdcp.gov.in\/Doc\/JE-AES-Prevention-Control(NPPCJA).pdf. Accessed 5 March 2021."},{"key":"10.1016\/j.jcv.2021.104970_bib0014","unstructured":"Central bureau of health intelligence, directorate general of health services, ministry of health and family welfare, government of India (2015). National Health Profile 2015. Available at https:\/\/cbhidghs.gov.in\/WriteReadData\/l892s\/NHP-2015.pdf. Accessed 5 March 2021."},{"key":"10.1016\/j.jcv.2021.104970_bib0015","unstructured":"Directorate, National Vector Borne Disease Control Programme, Government of India (2006). Guidelines for Surveillance of Acute Encephalitis Syndrome (with Special Reference to Japanese encephalitis). Available at https:\/\/nvbdcp.gov.in\/Doc\/AES%20guidelines.pdf. Accessed 5 March 2021."},{"key":"10.1016\/j.jcv.2021.104970_bib0016","unstructured":"National Centre for Disease Control (NCDC), Ministry of Health and Family Welfare, Government of India. Integrated Disease Surveillance Programme Training Manual for Medical Officers for Hospital Based Disease Surveillance. Available at https:\/\/idsp.nic.in\/WriteReadData\/OldSite\/MedOff.pdf. Accessed 5 March 2021."},{"key":"10.1016\/j.jcv.2021.104970_bib0017","unstructured":"Indian Bureaucracy (News). Health ministry issues notification on Japanese encephalitis (JE). https:\/\/www.indianbureaucracy.com\/health-ministry-issues-notification-on-japanese-encephalitis\/(24 September 2016). Accessed 5 March 2021."},{"issue":"11","key":"10.1016\/j.jcv.2021.104970_bib0018","first-page":"897","article-title":"Consensus guidelines on evaluation and management of suspected acute viral encephalitis in children in India","volume":"49","author":"Sharma","year":"2012","journal-title":"Indian Pediatr. 2012 Nov"},{"issue":"5","key":"10.1016\/j.jcv.2021.104970_bib0019","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/imj.12749","volume":"45","author":"Britton","year":"2015","journal-title":"Intern. Med. J."},{"issue":"6","key":"10.1016\/j.jcv.2021.104970_bib0020","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.4269\/ajtmh.2007.77.1139","article-title":"Detection and isolation of Japanese encephalitis virus from blood clots collected during the acute phase of infection","volume":"77","author":"Sapkal","year":"2007","journal-title":"Am. J. Trop. Med. Hyg"},{"issue":"5","key":"10.1016\/j.jcv.2021.104970_bib0021","first-page":"769","article-title":"Isolation of Chandipura virus (Vesiculovirus: rhabdoviridae) from Sergentomyia species of sandflies from Nagpur, Maharashtra, India","volume":"139","author":"Sudeep","year":"2014","journal-title":"Indian J. Med. Res."},{"key":"10.1016\/j.jcv.2021.104970_bib0022","doi-asserted-by":"crossref","first-page":"750","DOI":"10.4103\/ijmr.IJMR_747_14","article-title":"Genetic characterization of human herpesvirus type 1: full-length genome sequence of strain obtained from an encephalitis case from India","volume":"144","author":"Bondre","year":"2016","journal-title":"Indian J. Med. Res."},{"issue":"2","key":"10.1016\/j.jcv.2021.104970_bib0023","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3201\/eid1502.080865","article-title":"Enteroviruses in patients with acute encephalitis, Uttar Pradesh, India","volume":"15","author":"Sapkal","year":"2009","journal-title":"Emerging Infect. Dis."},{"key":"10.1016\/j.jcv.2021.104970_bib0024","unstructured":"Directorate of National vector borne disease control programme (NVBDCP), Government of India. State wise number of AES\/JE cases and deaths in the country since 2014. Available at https:\/\/nvbdcp.gov.in\/WriteReadData\/l892s\/58400378961617883165.pdf. Accessed 5 March 2021."},{"issue":"5","key":"10.1016\/j.jcv.2021.104970_bib0025","first-page":"459","article-title":"Neurology collaborators. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the global burden of disease study 2016 (2019)","volume":"18","year":"2016","journal-title":"Lancet Neurol."},{"issue":"4","key":"10.1016\/j.jcv.2021.104970_bib0026","doi-asserted-by":"crossref","first-page":"240","DOI":"10.4103\/0970-0218.103473","article-title":"Incidence rate of acute encephalitis syndrome without specific treatment in India and Nepal","volume":"37","author":"Potharaju","year":"2012","journal-title":"Indian J. Community Med"},{"issue":"9","key":"10.1016\/j.jcv.2021.104970_bib0027","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1016\/j.clineuro.2013.04.008","article-title":"Clinical presentation, etiology, and survival in adult acute encephalitis syndrome in rural central India","volume":"115","author":"Joshi","year":"2013","journal-title":"Clin. Neurol. Neurosurg"},{"issue":"11","key":"10.1016\/j.jcv.2021.104970_bib0028","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.18203\/2394-6040.ijcmph20163902","article-title":"Clinico-epidemiological profile of acute encephalitis syndrome in children of Bellary, Karnataka, India","volume":"3","author":"Kamble","year":"2016","journal-title":"Int. J. Community Med. Public Health"},{"issue":"4","key":"10.1016\/j.jcv.2021.104970_bib0029","doi-asserted-by":"crossref","first-page":"529","DOI":"10.4103\/ijmm.IJMM_17_180","article-title":"Aetiological study of viruses causing acute encephalitis syndrome in North West India","volume":"35","author":"Tiwari","year":"2017","journal-title":"Indian J. Med. Microbiol"},{"key":"10.1016\/j.jcv.2021.104970_bib0030","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.4103\/0028-3886.304080","article-title":"Determination of etiology and epidemiologyof viral central nervous system infections by quantitative real\u2011time polymerase chain reaction in central India population","volume":"68","author":"Tiwari","year":"2020","journal-title":"Neurol. India"},{"issue":"1","key":"10.1016\/j.jcv.2021.104970_bib0031","doi-asserted-by":"crossref","first-page":"19","DOI":"10.4103\/jnrp.jnrp_93_17","article-title":"Acute febrile encephalopathy in children: a prospective study of clinical features, etiology, mortality, and risk factors from western India (2018)","volume":"9","author":"Gupta","year":"2018","journal-title":"J. Neurosci. Rural Pract"},{"key":"10.1016\/j.jcv.2021.104970_bib0032","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.ijid.2020.03.039","article-title":"A need to raise the bar - a systematic review of temporal trends in diagnostics for Japanese encephalitis virus infection, and perspectives for future research","volume":"95","author":"Bharucha","year":"2020","journal-title":"Int. J. Infect. Dis"},{"key":"10.1016\/j.jcv.2021.104970_bib0033","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1016\/j.ijid.2019.01.008","article-title":"Dengue virus is an under-recognized causative agent of acute encephalitis syndrome (AES): results from a four year AES surveillance study of Japanese encephalitis in selected states of India","volume":"84S","author":"Vasanthapuram","year":"2019","journal-title":"Int. J. Infect. Dis"}],"container-title":["Journal of Clinical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653221002377?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1386653221002377?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:06:08Z","timestamp":1777615568000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1386653221002377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":33,"alternative-id":["S1386653221002377"],"URL":"https:\/\/doi.org\/10.1016\/j.jcv.2021.104970","relation":{},"ISSN":["1386-6532"],"issn-type":[{"value":"1386-6532","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Childhood encephalitis hospitalizations associated with virus agents in medium-endemic states in India","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcv.2021.104970","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104970"}}