{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:04:46Z","timestamp":1790006686617,"version":"4.0.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","award":["1K23HL151826NIH"],"award-info":[{"award-number":["1K23HL151826NIH"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007500","name":"Bloomberg Philanthropies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007500","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016819","name":"Octapharma","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016819","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016645","name":"Shear Family Foundation Inc","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000180","name":"US DHS","doi-asserted-by":"publisher","award":["W911QY2090012"],"award-info":[{"award-number":["W911QY2090012"]}],"id":[{"id":"10.13039\/100000180","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017443","name":"Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017443","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015283","name":"Bloomberg Philanthropies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015283","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["U24TR001609-S3"],"award-info":[{"award-number":["U24TR001609-S3"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017027","name":"State of Maryland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016300","name":"Octapharma AG","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016300","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["3R01AI152078-01S1"],"award-info":[{"award-number":["3R01AI152078-01S1"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Virology Plus"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jcvp.2026.100268","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:01:19Z","timestamp":1788969679000},"page":"100268","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Combined elevated C-reactive protein and detectable plasma RNA has predictive value for hospitalization during an outpatient COVID-19 convalescent plasma clinical trial"],"prefix":"10.1016","volume":"6","author":[{"given":"Yuriko","family":"Fukuta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atika","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangda","family":"Ou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leilani","family":"Montalvo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara Di","family":"Germanio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moises A.","family":"Huaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aarthi G.","family":"Shenoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giselle S.","family":"Mosnaim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bela","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonya L.","family":"Heath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam C.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry R.","family":"Meisenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Anjan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janis E.","family":"Blair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith S.","family":"Currier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James H.","family":"Paxton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Gerber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura L.","family":"Hammitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine G.","family":"Sutcliffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Rausch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick B.","family":"Broderick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Elena","family":"Cordisco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Greenblatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie C.","family":"Cluzet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cruser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Oei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Abinante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald N.","family":"Forthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin S.","family":"Zand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seble G.","family":"Kassaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward R.","family":"Cachay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay S.","family":"Raval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Gniadek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Spivak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly A.","family":"Gebo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shmuel","family":"Shoham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arturo","family":"Casadevall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nichol A.","family":"McBee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Shade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Ehrardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Layendecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabra L.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan M.","family":"Bloch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron A.R.","family":"Tobian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Ford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Lane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel F.","family":"Hanley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Pekosz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J.","family":"Norris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0319-0578","authenticated-orcid":false,"given":"David J.","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcvp.2026.100268_bib0001","doi-asserted-by":"crossref","first-page":"6141","DOI":"10.1172\/JCI142004","article-title":"Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population","volume":"130","author":"Klein","year":"2020","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jcvp.2026.100268_bib0002","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1093\/ije\/dyab012","article-title":"The role of C-reactive protein as a prognostic marker in COVID-19","volume":"50","author":"Stringer","year":"2021","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.jcvp.2026.100268_bib0003","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1136\/bmjebm-2020-111536","article-title":"Biomarkers and outcomes of COVID-19 hospitalisations: systematic review and meta-analysis","volume":"26","author":"Malik","year":"2021","journal-title":"BMJ Evid. Based Med."},{"key":"10.1016\/j.jcvp.2026.100268_bib0004","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1515\/cclm-2023-0276","article-title":"C-reactive protein and clinical outcome in COVID-19 patients: the importance of harmonized measurements","volume":"61","author":"Aloisio","year":"2023","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.jcvp.2026.100268_bib0005","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1111\/aas.14109","article-title":"Longitudinal changes in inflammatory biomarkers among patients with COVID-19: a nationwide study in Iceland","volume":"66","author":"Oskarsdottir","year":"2022","journal-title":"Acta Anaesthesiol. Scand."},{"key":"10.1016\/j.jcvp.2026.100268_bib0006","article-title":"Accuracy of routine laboratory tests to predict mortality and deterioration to severe or critical COVID-19 in people with SARS-CoV-2","volume":"8","author":"De Rop","year":"2024","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.jcvp.2026.100268_bib0007","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1093\/cid\/ciab686","article-title":"Severe acute respiratory syndrome coronavirus 2 viremia is associated with coronavirus disease 2019 severity and predicts clinical outcomes","volume":"74","author":"Jacobs","year":"2022","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jcvp.2026.100268_bib0008","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1186\/s13054-020-03398-0","article-title":"Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19","volume":"24","author":"Bermejo-Martin","year":"2020","journal-title":"Crit. Care"},{"key":"10.1016\/j.jcvp.2026.100268_bib0009","doi-asserted-by":"crossref","DOI":"10.3390\/v12091045","article-title":"RNAemia corresponds to disease severity and antibody response in hospitalized COVID-19 patients","volume":"12","author":"Eberhardt","year":"2020","journal-title":"Viruses"},{"key":"10.1016\/j.jcvp.2026.100268_bib0010","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1186\/s12985-024-02526-4","article-title":"SARS-CoV-2 RNAemia as a reliable predictor of long-term mortality among older adults hospitalized in pulmonary intermediate care units: a prospective cohort study","volume":"21","author":"Liang","year":"2024","journal-title":"Virol. J."},{"key":"10.1016\/j.jcvp.2026.100268_bib0011","doi-asserted-by":"crossref","first-page":"3406","DOI":"10.1038\/s41467-021-23494-1","article-title":"SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care","volume":"12","author":"Gutmann","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jcvp.2026.100268_bib0012","doi-asserted-by":"crossref","first-page":"e291","DOI":"10.1093\/cid\/ciaa1054","article-title":"High frequency of SARS-CoV-2 RNAemia and association with severe disease","volume":"72","author":"Hogan","year":"2021","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jcvp.2026.100268_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.104075","article-title":"Association of high SARS-CoV-2 RNAemia with diabetes and mortality in critically ill COVID-19 patients","volume":"25","author":"Monchi","year":"2022","journal-title":"iScience"},{"key":"10.1016\/j.jcvp.2026.100268_bib0014","first-page":"362","article-title":"SARS-CoV-2 and post-donation information: a one-year experience of the French haemovigilance network","volume":"20","author":"Cappy","year":"2022","journal-title":"Blood Transfus."},{"key":"10.1016\/j.jcvp.2026.100268_bib0015","doi-asserted-by":"crossref","DOI":"10.1172\/JCI159876","article-title":"Frequent detection but lack of infectivity of SARS-CoV-2 RNA in presymptomatic, infected blood donor plasma","volume":"132","author":"Sa\u00e1","year":"2022","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jcvp.2026.100268_bib0016","doi-asserted-by":"crossref","first-page":"ofad253","DOI":"10.1093\/ofid\/ofad253","article-title":"Prevalence of SARS-CoV-2 viremia in presymptomatic blood donors in the delta and omicron variant eras","volume":"10","author":"Saa","year":"2023","journal-title":"Open Forum Infect. Dis."},{"key":"10.1016\/j.jcvp.2026.100268_bib0017","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1093\/cid\/ciab394","article-title":"SARS-CoV-2 RNAemia predicts clinical deterioration and extrapulmonary complications from COVID-19","volume":"74","author":"Ram-Mohan","year":"2022","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jcvp.2026.100268_bib0018","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1093\/infdis\/jiaf109","article-title":"Viral and immune factors associated with COVID-19 outcome in the C3PO trial of convalescent plasma","volume":"231","author":"Di Germanio","year":"2025","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jcvp.2026.100268_bib0019","article-title":"Prevalence and clinical relevance of viraemia in viral respiratory tract infections: a systematic review","author":"Hagman","year":"2024","journal-title":"Lancet Microbe"},{"key":"10.1016\/j.jcvp.2026.100268_bib0020","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1501872","article-title":"Prognostic performance of early immune and endothelial activation markers in mild-to-moderate COVID-19 outpatients: a nested case-control study","volume":"15","author":"Alemany","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jcvp.2026.100268_bib0021","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0269005","article-title":"Clinical utility of inflammatory biomarkers in COVID-19 in direct comparison to other respiratory infections-A prospective cohort study","volume":"17","author":"Lampart","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.jcvp.2026.100268_bib0022","first-page":"27","article-title":"Predictive prognostic biomarkers in patients with COVID\u201119 infection","author":"Fukui","year":"2023","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.jcvp.2026.100268_bib0023","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1056\/NEJMoa2119657","article-title":"Early outpatient treatment for Covid-19 with convalescent plasma","volume":"386","author":"Sullivan","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jcvp.2026.100268_bib0024","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.3201\/eid2608.201246","article-title":"US CDC real-time reverse transcription PCR panel for detection of severe acute respiratory syndrome coronavirus 2","volume":"26","author":"Lu","year":"2020","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.jcvp.2026.100268_bib0025","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1097\/01.ede.0000135174.63482.43","article-title":"A structural approach to selection bias","volume":"15","author":"Hern\u00e1n","year":"2004","journal-title":"Epidemiology"},{"key":"10.1016\/j.jcvp.2026.100268_bib0026","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1002\/sim.1047","article-title":"A solution to the problem of separation in logistic regression","volume":"21","author":"Heinze","year":"2002","journal-title":"Stat. Med."},{"key":"10.1016\/j.jcvp.2026.100268_bib0027","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1056\/NEJMoa2103784","article-title":"Early convalescent plasma for high-risk outpatients with Covid-19","volume":"385","author":"Korley","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jcvp.2026.100268_bib0028","doi-asserted-by":"crossref","first-page":"e217","DOI":"10.1016\/S1473-3099(18)30127-0","article-title":"Middle East respiratory syndrome coronavirus: risk factors and determinants of primary, household, and nosocomial transmission","volume":"18","author":"Hui","year":"2018","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jcvp.2026.100268_bib0029","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1373\/clinchem.2003.024125","article-title":"Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome","volume":"49","author":"Ng","year":"2003","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jcvp.2026.100268_bib0030","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1056\/NEJMoa1411680","article-title":"Clinical illness and outcomes in patients with Ebola in Sierra Leone","volume":"371","author":"Schieffelin","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jcvp.2026.100268_bib0031","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1038\/nm1477","article-title":"Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia","volume":"12","author":"de Jong","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.jcvp.2026.100268_bib0032","doi-asserted-by":"crossref","first-page":"S117","DOI":"10.1093\/infdis\/jiad287","article-title":"Association between anterior nasal and plasma SARS-CoV-2 RNA levels and hospitalization or death in nonhospitalized adults with mild-to-moderate COVID-19","volume":"228","author":"Giganti","year":"2023","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jcvp.2026.100268_bib0033","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-92400-y","article-title":"SARS-CoV-2 viral load in nasopharyngeal swabs is not an independent predictor of unfavorable outcome","volume":"11","author":"Salto-Alejandre","year":"2021","journal-title":"Sci. Rep."}],"container-title":["Journal of Clinical Virology Plus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667038026000281?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667038026000281?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T15:27:19Z","timestamp":1790004439000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667038026000281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S2667038026000281"],"URL":"https:\/\/doi.org\/10.1016\/j.jcvp.2026.100268","relation":{},"ISSN":["2667-0380"],"issn-type":[{"value":"2667-0380","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Combined elevated C-reactive protein and detectable plasma RNA has predictive value for hospitalization during an outpatient COVID-19 convalescent plasma clinical trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Virology Plus","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcvp.2026.100268","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100268"}}