{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:55:08Z","timestamp":1787320508140,"version":"build-2736575974"},"reference-count":34,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["celltherapyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytotherapy"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.jcyt.2013.03.002","type":"journal-article","created":{"date-parts":[[2013,4,18]],"date-time":"2013-04-18T05:51:20Z","timestamp":1366264280000},"page":"1011-1020","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":72,"title":["Investigating the efficacy of amnion-derived compared with bone marrow\u2013derived mesenchymal stromal cells in equine tendon and ligament injuries"],"prefix":"10.1016","volume":"15","author":[{"given":"Anna","family":"Lange-Consiglio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Tassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna","family":"Corradetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurora","family":"Meucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Perego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Bizzaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fausto","family":"Cremonesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcyt.2013.03.002_bib1","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/j.1532-950X.2006.00142.x","article-title":"Mesenchymal stem cells and bone regeneration","volume":"35","author":"Kraus","year":"2006","journal-title":"Vet Surg"},{"key":"10.1016\/j.jcyt.2013.03.002_bib2","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.joca.2006.05.002","article-title":"Repair of superficial osteochondral defects with an autologous scaffold-free cartilage construct in a caprine model: implantation method and short-term results","volume":"14","author":"Brehm","year":"2006","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.jcyt.2013.03.002_bib3","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1002\/jor.20382","article-title":"Enhanced early chondrogenesis in articular defects following arthroscopic mesenchymal stem cell implantation in an equine model","volume":"25","author":"Wilke","year":"2007","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.jcyt.2013.03.002_bib4","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.tibtech.2007.07.009","article-title":"Stem cells in veterinary medicine-attempts at regenerating equine tendon after injury","volume":"25","author":"Richardson","year":"2007","journal-title":"Trends Biotechnol"},{"issue":"Pt 11","key":"10.1016\/j.jcyt.2013.03.002_bib5","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1242\/jcs.02932","article-title":"Mesenchymal stem cells reside in virtually all post-natal organs and tissues","volume":"119","author":"da Silva Meirelles","year":"2006","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.jcyt.2013.03.002_bib6","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1002\/term.465","article-title":"Characterization and potential applications of progenitor-like cells isolated from horse amniotic membrane","volume":"6","author":"Lange-Consiglio","year":"2012","journal-title":"J\u00a0Tissue Eng Regen Med"},{"key":"10.1016\/j.jcyt.2013.03.002_bib7","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1016\/j.theriogenology.2010.12.032","article-title":"Fetal adnexa derived stem cells from domestic animal: progress and perspectives","volume":"75","author":"Cremonesi","year":"2011","journal-title":"Theriogenology"},{"key":"10.1016\/j.jcyt.2013.03.002_bib8","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1111\/j.2042-3306.2010.00112.x","article-title":"Equine embryonic stem-like cells and mesenchymal stromal cells have different survival rates and migration patterns following their injection into damaged superficial digital flexor tendon","volume":"42","author":"Guest","year":"2010","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jcyt.2013.03.002_bib9","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/scrt45","article-title":"Fetal derived embryonic-like stem cells improve healing in a large animal flexor tendonitis model","volume":"2","author":"Watts","year":"2011","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.jcyt.2013.03.002_bib10","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s11259-010-9457-3","article-title":"Comparison of equine bone marrow-, umbilical cord matrix and amniotic fluid-derived progenitor cells","volume":"35","author":"Lovati","year":"2011","journal-title":"Vet Res Commun"},{"key":"10.1016\/j.jcyt.2013.03.002_bib11","series-title":"Diagnosis and Management of Lameness in the Horse","first-page":"66","article-title":"Ultrasonographic evaluation of the equine limb: technique","author":"Rantanen","year":"2003"},{"key":"10.1016\/j.jcyt.2013.03.002_bib12","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.cveq.2007.11.002","article-title":"Regenerative medicine for tendinous and ligamentous injuries of sport horses","volume":"24","author":"Fortier","year":"2008","journal-title":"Vet Clin North Am Equine Pract"},{"key":"10.1016\/j.jcyt.2013.03.002_bib13","first-page":"155","article-title":"Current and future regenerative medicine: principles, concepts, and therapeutic use of stem cell therapy and tissue engineering in equine medicine","volume":"50","author":"Koch","year":"2009","journal-title":"Can Vet J"},{"key":"10.1016\/j.jcyt.2013.03.002_bib14","article-title":"Histological and immunohistochemical evaluation of autologous cultured bone marrow mesenchymal stem cells and bone marrow mononucleated cells in collagenase-induced tendinitis of equine superficial digital flexor tendon","volume":"250978","author":"Crovace","year":"2010","journal-title":"Vet Med Int"},{"key":"10.1016\/j.jcyt.2013.03.002_bib15","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/j.1532-950X.2007.00313.x","article-title":"Characterization of equine adipose tissue-derived stromal cells: adipogenic and osteogenic capacity and comparison with bone marrow-derived mesenchymal stromal cells","volume":"36","author":"Vidal","year":"2007","journal-title":"Vet Surg"},{"key":"10.1016\/j.jcyt.2013.03.002_bib16","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s11259-008-9093-3","article-title":"Equine adipose-tissue derived mesenchymal stem cells and platelet concentrates: their association in vitro and in vivo","volume":"32(Suppl 1):S","author":"Del Bue","year":"2008","journal-title":"Vet Res Commun"},{"key":"10.1016\/j.jcyt.2013.03.002_bib17","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.rvsc.2010.07.024","article-title":"Canine adipose-derived-mesenchymal stem cells do not lose stem features after a long-term cryopreservation","volume":"91","author":"Martinello","year":"2011","journal-title":"Res Vet Sci"},{"key":"10.1016\/j.jcyt.2013.03.002_bib18","first-page":"326","volume":"64","author":"Jezierska-Wo\u017aniak","year":"2010","journal-title":"Use of adipose tissue as a source of mesenchymal stem cells. Postepy Hig Med Dosw (Online)"},{"key":"10.1016\/j.jcyt.2013.03.002_bib19","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1016\/j.exphem.2005.07.003","article-title":"Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood","volume":"33","author":"Wagner","year":"2005","journal-title":"Exp Hematol"},{"key":"10.1016\/j.jcyt.2013.03.002_bib20","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1007\/s11259-009-9229-0","article-title":"Isolation, growth and differentiation of equine mesenchymal stem cells: effect of donor, source, amount of tissue and supplementation with basic fibroblast growth factor","volume":"33","author":"Colleoni","year":"2009","journal-title":"Vet Res Commun"},{"key":"10.1016\/j.jcyt.2013.03.002_bib21","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/978-1-61737-960-4_6","article-title":"Adipogenic differentiation of adult equine mesenchymal stromal cells","volume":"702","author":"Vidal","year":"2011","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jcyt.2013.03.002_bib22","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00441-006-0308-z","article-title":"Comparison of rat mesenchymal stem cells derived from bone marrow, synovium, periosteum, adipose tissue, and muscle","volume":"327","author":"Yoshimura","year":"2007","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.jcyt.2013.03.002_bib23","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1532-950X.2008.00462.x","article-title":"Comparison of chondrogenic potential in equine mesenchymal stromal cells derived from adipose tissue and bone marrow","volume":"37","author":"Vidal","year":"2008","journal-title":"Vet Surg"},{"key":"10.1016\/j.jcyt.2013.03.002_bib24","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/j.1365-2184.2011.00759.x","article-title":"Size-sieved subpopulations of mesenchymal stem cells from intervascular and perivascular equine umbilical cord matrix","volume":"44","author":"Corradetti","year":"2011","journal-title":"Cell Prolif"},{"key":"10.1016\/j.jcyt.2013.03.002_bib25","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3109\/14653249.2010.536213","article-title":"Clinicopathologic findings following intra-articular injection of autologous and allogeneic placentally derived equine mesenchymal stem cells in horses","volume":"13","author":"Carrade","year":"2011","journal-title":"Cytotherapy"},{"key":"10.1016\/j.jcyt.2013.03.002_bib26","doi-asserted-by":"crossref","first-page":"4598","DOI":"10.2741\/3552","article-title":"Mesenchymal stem cells and tendon healing","volume":"14","author":"Chong","year":"2009","journal-title":"Front Biosci"},{"key":"10.1016\/j.jcyt.2013.03.002_bib27","doi-asserted-by":"crossref","first-page":"667","DOI":"10.3727\/096368910X508762","article-title":"Mesenchymal stem cells: mechanisms of immunomodulation and homing","volume":"19","author":"Yagi","year":"2010","journal-title":"Cell Transplant"},{"key":"10.1016\/j.jcyt.2013.03.002_bib28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/scrt50","article-title":"Stem cells in veterinary medicine","volume":"2","author":"Fortier","year":"2011","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.jcyt.2013.03.002_bib29","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2527\/jas.2012-5736","article-title":"Growth and development symposium: Stem cell therapy in equine tendon injury","volume":"91","author":"Reed","year":"2013","journal-title":"J Anim Sci"},{"key":"10.1016\/j.jcyt.2013.03.002_bib30","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.cveq.2011.06.001","article-title":"Cell-based therapies for tendon and ligament injuries","volume":"27","author":"Alves","year":"2011","journal-title":"Vet Clin North Am Equine Pract"},{"key":"10.1016\/j.jcyt.2013.03.002_bib31","doi-asserted-by":"crossref","first-page":"99","DOI":"10.2746\/042516403775467388","article-title":"Isolation and implantation of autologous equine mesenchymal stem cells from bone marrow into the superficial digital flexor tendon as a potential novel treatment","volume":"35","author":"Smith","year":"2003","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jcyt.2013.03.002_bib32","doi-asserted-by":"crossref","first-page":"415","DOI":"10.2746\/0425164044868422","article-title":"Medical management of superficial digital flexor tendonitis: a comparative study in 219 horses (1992\u20132000)","volume":"36","author":"Dyson","year":"2004","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jcyt.2013.03.002_bib33","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.2042-3306.2012.00552.x","article-title":"Risk factors for superficial digital flexor tendinopathy in Thoroughbred racehorses in hurdle starts in the UK (2001\u20132009)","volume":"44","author":"Reardon","year":"2012","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jcyt.2013.03.002_bib34","series-title":"Diagnosis and Management of Lameness in the Horse","first-page":"975","article-title":"Lameness in the dressage horse","author":"Kold","year":"2003"}],"container-title":["Cytotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1465324913004490?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1465324913004490?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T22:17:45Z","timestamp":1761430665000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1465324913004490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":34,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S1465324913004490"],"URL":"https:\/\/doi.org\/10.1016\/j.jcyt.2013.03.002","relation":{},"ISSN":["1465-3249"],"issn-type":[{"value":"1465-3249","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Investigating the efficacy of amnion-derived compared with bone marrow\u2013derived mesenchymal stromal cells in equine tendon and ligament injuries","name":"articletitle","label":"Article Title"},{"value":"Cytotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcyt.2013.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}