{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:25:02Z","timestamp":1791267902842,"version":"4.1.0"},"reference-count":164,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000024","name":"the Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["celltherapyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytotherapy"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.jcyt.2014.04.004","type":"journal-article","created":{"date-parts":[[2014,6,13]],"date-time":"2014-06-13T14:32:02Z","timestamp":1402669922000},"page":"1171-1186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":79,"title":["Distinct phenotype and therapeutic potential of gingival fibroblasts"],"prefix":"10.1016","volume":"16","author":[{"given":"Lari","family":"H\u00e4kkinen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannu","family":"Larjava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin P.J.","family":"Fournier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcyt.2014.04.004_bib1","doi-asserted-by":"crossref","first-page":"258","DOI":"10.3324\/haematol.13699","article-title":"Mesenchymal stem cells: the fibroblasts' new clothes?","volume":"94","author":"Haniffa","year":"2009","journal-title":"Haematologica"},{"key":"10.1016\/j.jcyt.2014.04.004_bib2","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1016\/j.yexcr.2010.04.032","article-title":"Activation of fibroblasts in cancer stroma","volume":"316","author":"R\u00e4s\u00e4nen","year":"2010","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/etp.12008","article-title":"Granulation tissue formation and remodeling","volume":"24","author":"H\u00e4kkinen","year":"2012","journal-title":"Endodontic Topics"},{"key":"10.1016\/j.jcyt.2014.04.004_bib4","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1242\/jcs.01005","article-title":"Fibroblast heterogeneity: more than skin deep","volume":"117","author":"Sorrell","year":"2004","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.jcyt.2014.04.004_bib5","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1089\/scd.2013.0015","article-title":"Gingiva as a source of stem cells with therapeutic potential","volume":"22","author":"Fournier","year":"2013","journal-title":"Stem Cells Dev"},{"key":"10.1016\/j.jcyt.2014.04.004_bib6","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells: the International Society for Cellular Therapy position statement","volume":"8","author":"Dominici","year":"2006","journal-title":"Cytotherapy"},{"key":"10.1016\/j.jcyt.2014.04.004_bib7","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1007\/s00109-012-0915-y","article-title":"Mesenchymal stromal cells (MSCs): science and f(r)iction","volume":"90","author":"Bieback","year":"2012","journal-title":"J\u00a0Mol Med"},{"key":"10.1016\/j.jcyt.2014.04.004_bib8","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.stem.2012.08.010","article-title":"Stem cells in the face: tooth regeneration and beyond","volume":"11","author":"Mao","year":"2012","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jcyt.2014.04.004_bib9","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1242\/jcs.1988.Supplement_10.9","article-title":"Differentiation of fibroblast stem cells","volume":"10","author":"Bayreuther","year":"1988","journal-title":"J\u00a0Cell Sci Suppl"},{"key":"10.1016\/j.jcyt.2014.04.004_bib10","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1177\/00220345920710120901","article-title":"Characterization of fibroblast clones from periodontal granulation tissue in vitro","volume":"71","author":"H\u00e4kkinen","year":"1992","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib11","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1242\/jcs.107.5.1333","article-title":"Inter- and intra-site heterogeneity in the expression of fetal-like phenotypic characteristics by gingival fibroblasts: potential significance for wound healing","volume":"107","author":"Irwin","year":"1994","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.jcyt.2014.04.004_bib12","doi-asserted-by":"crossref","first-page":"12877","DOI":"10.1073\/pnas.162488599","article-title":"Diversity, topographic differentiation, and positional memory in human fibroblasts","volume":"99","author":"Chang","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jcyt.2014.04.004_bib13","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1601-0825.1996.tb00217.x","article-title":"Subpopulations of fetal-like gingival fibroblasts: characterisation and potential significance for wound healing and the progression of periodontal disease","volume":"2","author":"Schor","year":"1996","journal-title":"Oral Dis"},{"key":"10.1016\/j.jcyt.2014.04.004_bib14","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.exphem.2010.03.004","article-title":"Fibrocytes in health and disease","volume":"38","author":"Herzog","year":"2010","journal-title":"Exp Hematol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib15","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/0003-9969(83)90010-9","article-title":"Evidence that healthy human gingiva contains functionally heterogeneous fibroblast subpopulations","volume":"28","author":"Hassell","year":"1983","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib16","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1242\/jcs.90.3.391","article-title":"Foetal and cancer patient fibroblasts produce an autocrine migration-stimulating factor not made by normal adult cells","volume":"90","author":"Schor","year":"1988","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.jcyt.2014.04.004_bib17","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1073\/pnas.86.7.2438","article-title":"Purification of the migration stimulating factor produced by fetal and breast cancer patient fibroblasts","volume":"86","author":"Grey","year":"1989","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jcyt.2014.04.004_bib18","doi-asserted-by":"crossref","first-page":"3429","DOI":"10.1073\/pnas.74.8.3429","article-title":"Fibroblast heterogeneity and prostaglandin regulation of subpopulations","volume":"74","author":"Ko","year":"1977","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jcyt.2014.04.004_bib19","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1126\/science.6691142","article-title":"Heterogeneity of normal human diploid fibroblasts: isolation and characterization of one phenotype","volume":"223","author":"Bordin","year":"1984","journal-title":"Science"},{"key":"10.1016\/j.jcyt.2014.04.004_bib20","first-page":"993","article-title":"Lymphocyte-mediated effects of cyclosporine on human fibroblasts","volume":"20","author":"Hassell","year":"1988","journal-title":"Transplant Proc"},{"key":"10.1016\/j.jcyt.2014.04.004_bib21","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1006\/clin.1994.1144","article-title":"Evidence of fibroblast heterogeneity and the role of fibroblast subpopulations in fibrosis","volume":"72","author":"Fries","year":"1994","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib22","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1046\/j.1524-475X.1995.30204.x","article-title":"Fibroblast heterogeneity in the healing wound","volume":"3","author":"Sempowski","year":"1995","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.jcyt.2014.04.004_bib23","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1177\/10454411970080030201","article-title":"Is fibroblast heterogeneity relevant to the health, diseases, and treatments of periodontal tissues?","volume":"8","author":"Lekic","year":"1997","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.jcyt.2014.04.004_bib24","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1600-0722.2006.00388.x","article-title":"Expression of stem cell factor and its receptor, c-kit, in human oral mesenchymal cells","volume":"114","author":"Gagari","year":"2006","journal-title":"Eur J Oral Sci"},{"key":"10.1016\/j.jcyt.2014.04.004_bib25","first-page":"642","article-title":"Fibroblast heterogeneity of signal transduction mechanisms to complement-C1q: analyses of calcium mobilization, inositol phosphate accumulation, and protein kinases-C redistribution","volume":"69","author":"Bordin","year":"1998","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib26","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/154411130401500305","article-title":"Connective tissue metabolism and gingival overgrowth","volume":"15","author":"Trackman","year":"2004","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.jcyt.2014.04.004_bib27","first-page":"218","article-title":"Phenytoin sensitivity of fibroblasts as the basis for susceptibility to gingival enlargement","volume":"112","author":"Hassell","year":"1983","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib28","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1600-0714.2004.00217.x","article-title":"Extracellular glycosaminoglycan changes in healthy and overgrown gingiva fibroblasts after cyclosporin A and cytokine treatments","volume":"33","author":"Stabellini","year":"2004","journal-title":"J\u00a0Oral Pathol Med"},{"key":"10.1016\/j.jcyt.2014.04.004_bib29","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1097\/01.PRS.0000101530.33096.5B","article-title":"The effect of myofibroblast on contracture of hypertrophic scar","volume":"113","author":"Shin","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib30","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/BF03403533","article-title":"Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair","volume":"1","author":"Bucala","year":"1994","journal-title":"Mol Med"},{"key":"10.1016\/j.jcyt.2014.04.004_bib31","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1007\/s12015-011-9340-9","article-title":"Adult craniofacial stem cells: sources and relation to the neural crest","volume":"8","author":"Kaltschmidt","year":"2011","journal-title":"Stem Cell Rev"},{"key":"10.1016\/j.jcyt.2014.04.004_bib32","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1600-0765.1971.tb00619.x","article-title":"Conservation of tissue specificity after heterotopic transplantation of gingiva and alveolar mucosa","volume":"6","author":"Karring","year":"1971","journal-title":"J\u00a0Periodont Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0765.1975.tb00001.x","article-title":"The role of gingival connective tissue in determining epithelial differentiation","volume":"10","author":"Karring","year":"1975","journal-title":"J\u00a0Periodont Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib34","series-title":"Oral Structural Biology","author":"Schroeder","year":"1991"},{"key":"10.1016\/j.jcyt.2014.04.004_bib35","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0738-081X(00)00140-1","article-title":"Oral mucosal embryology and histology","volume":"18","author":"Winning","year":"2000","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib36","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jdermsci.2009.09.005","article-title":"Scarless healing of oral mucosa is characterized by faster resolution of inflammation and control of myofibroblast action compared to skin wounds in the red Duroc pig model","volume":"56","author":"Mak","year":"2009","journal-title":"J\u00a0Dermatol Sci"},{"key":"10.1016\/j.jcyt.2014.04.004_bib37","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.1524-475X.2009.00531.x","article-title":"Wound healing in oral mucosa results in reduced scar formation as compared with skin: evidence from the red Duroc pig model and humans","volume":"17","author":"Wong","year":"2009","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.jcyt.2014.04.004_bib38","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1111\/wrr.12072","article-title":"Detrimental dermal wound healing: what can we learn from the oral mucosa?","volume":"21","author":"Glim","year":"2013","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.jcyt.2014.04.004_bib39","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/j.1600-0714.1978.tb01596.x","article-title":"A\u00a0fine structural comparison of the healing of incisional wounds of mucosa and skin","volume":"7","author":"Sciubba","year":"1978","journal-title":"J\u00a0Oral Pathol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib40","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1177\/154405910308200810","article-title":"Differential injury responses in oral mucosal and cutaneous wounds","volume":"82","author":"Szpaderska","year":"2003","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib41","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1177\/00220345950740120301","article-title":"Saliva and growth factors: the fountain of youth resides in us all","volume":"74","author":"Zelles","year":"1995","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib42","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1034\/j.1600-0757.2000.2240107.x","article-title":"Cell biology of gingival wound healing","volume":"24","author":"H\u00e4kkinen","year":"2000","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.jcyt.2014.04.004_bib43","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1160\/TH03-07-0446","article-title":"Aberrant mucosal wound repair in the absence of secretory leukocyte protease inhibitor","volume":"92","author":"Angelov","year":"2004","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jcyt.2014.04.004_bib44","doi-asserted-by":"crossref","first-page":"3805","DOI":"10.1096\/fj.08-112003","article-title":"Histatins are the major wound-closure stimulating factors in human saliva as identified in a cell culture assay","volume":"22","author":"Oudhoff","year":"2008","journal-title":"FASEB J"},{"key":"10.1016\/j.jcyt.2014.04.004_bib45","first-page":"4","article-title":"Salivary histatin 3 inhibits heat shock cognate protein 70-mediated inflammatory cytokine production through toll-like receptors in human gingival fibroblasts","volume":"11","author":"Imamura","year":"2014","journal-title":"J\u00a0Inflamm"},{"issue":"Suppl","key":"10.1016\/j.jcyt.2014.04.004_bib46","doi-asserted-by":"crossref","first-page":"223S","DOI":"10.1016\/0003-9969(90)90163-5","article-title":"The elastic system fibres in healthy human gingiva","volume":"35","author":"Chavrier","year":"1990","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib47","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/j.1600-051X.2010.01542.x","article-title":"Elastin in oral connective tissue modulates the keratinization of overlying epithelium","volume":"37","author":"Hsieh","year":"2010","journal-title":"J\u00a0Clin Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib48","first-page":"1178","article-title":"Biomechanical behavior of oral soft tissues","volume":"82","author":"Goktas","year":"2011","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib49","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1369\/jhc.2009.952572","article-title":"Expression of integrin alphavbeta6 and TGF-beta in scarless vs scar-forming wound healing","volume":"57","author":"Eslami","year":"2009","journal-title":"J\u00a0Histochem Cytochem"},{"key":"10.1016\/j.jcyt.2014.04.004_bib50","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1365-4632.2010.04678.x","article-title":"Strategies for prevention of scars: what can we learn from fetal skin?","volume":"50","author":"Namazi","year":"2011","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib51","doi-asserted-by":"crossref","first-page":"e90715","DOI":"10.1371\/journal.pone.0090715","article-title":"Human gingival fibroblasts display a non-fibrotic phenotype distinct from skin fibroblasts in three-dimensional cultures","volume":"9","author":"Mah","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.jcyt.2014.04.004_bib52","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1034\/j.1600-0757.2000.2240102.x","article-title":"Development and general structure of the periodontium","volume":"24","author":"Cho","year":"2000","journal-title":"Periodontology"},{"key":"10.1016\/j.jcyt.2014.04.004_bib53","first-page":"70","article-title":"Structural constituents of clinically normal and slightly inflamed dog gingiva: a morphometric study","volume":"17","author":"Schroeder","year":"1973","journal-title":"Helv Odontol Acta"},{"key":"10.1016\/j.jcyt.2014.04.004_bib54","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1600-0757.1997.tb00094.x","article-title":"The periodontal ligament: a unique, multifunctional connective tissue","volume":"13","author":"Beertsen","year":"1997","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.jcyt.2014.04.004_bib55","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1177\/00220345880670011301","article-title":"A\u00a0comparative study of human periodontal ligament cells and gingival fibroblasts in vitro","volume":"67","author":"Somerman","year":"1988","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib56","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1177\/00220345950740070901","article-title":"Alkaline phosphatase activity in the periodontal ligament and gingiva of the rat molar: its relation to cementum formation","volume":"74","author":"Groeneveld","year":"1995","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib57","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1177\/00220345960750030601","article-title":"Functional characteristics of gingival and periodontal ligament fibroblasts","volume":"75","author":"Giannopoulou","year":"1996","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib58","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1600-0765.2007.01028.x","article-title":"Modulation of gingival epithelial phenotypes by interactions with regionally defined populations of fibroblasts","volume":"43","author":"Locke","year":"2008","journal-title":"J\u00a0Periodont Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib59","first-page":"226","article-title":"Development of an in vitro wound healing model for periodontal cells","volume":"71","author":"Lackler","year":"2000","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib60","first-page":"310","article-title":"Differential production of macrophage inflammatory protein-1alpha, stromal-derived factor-1, and IL-6 by human cultured periodontal ligament and gingival fibroblasts challenged with lipopolysaccharide from P. gingivalis","volume":"81","author":"Morandini","year":"2010","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib61","first-page":"284","article-title":"CD40 mediated activation of gingival and periodontal ligament fibroblasts","volume":"68","author":"Sempowski","year":"1997","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib62","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1600-0765.2006.00944.x","article-title":"Identification of marker genes distinguishing human periodontal ligament cells from human mesenchymal stem cells and human gingival fibroblasts","volume":"42","author":"Fujita","year":"2007","journal-title":"J\u00a0Periodont Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib63","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1242\/jcs.100.1.187","article-title":"Quantitation of actin polymerization in two human fibroblast sub-types responding to mechanical stretching","volume":"100","author":"Pender","year":"1991","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.jcyt.2014.04.004_bib64","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3109\/03008200009005642","article-title":"Cell surface proteoglycan expression by human periodontal cells","volume":"41","author":"Worapamorn","year":"2000","journal-title":"Connect Tissue Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib65","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1034\/j.1600-0765.2002.00662.x","article-title":"Expression of fibrillins and tropoelastin by human gingival and periodontal ligament fibroblasts in vitro","volume":"37","author":"Tsuruga","year":"2002","journal-title":"J\u00a0Periodont Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib66","first-page":"88","article-title":"Skin scarring","volume":"326","author":"Bayat","year":"2003","journal-title":"Br\u00a0Med J"},{"key":"10.1016\/j.jcyt.2014.04.004_bib67","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1098\/rsif.2006.0179","article-title":"Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration","volume":"4","author":"Metcalfe","year":"2007","journal-title":"J\u00a0R Soc Interface"},{"key":"10.1016\/j.jcyt.2014.04.004_bib68","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.drudis.2008.08.009","article-title":"New therapeutics for the prevention and reduction of scarring","volume":"13","author":"Occleston","year":"2008","journal-title":"Drug Discov Today"},{"key":"10.1016\/j.jcyt.2014.04.004_bib69","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0305-4179(03)00067-6","article-title":"What is the prevalence of hypertrophic scarring following burns?","volume":"29","author":"Bombaro","year":"2003","journal-title":"Burns"},{"key":"10.1016\/j.jcyt.2014.04.004_bib70","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/wrr.12029","article-title":"The role of skin substitutes in the management of chronic cutaneous wounds","volume":"21","author":"Greaves","year":"2013","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.jcyt.2014.04.004_bib71","doi-asserted-by":"crossref","first-page":"e60","DOI":"10.1097\/BCR.0b013e31827039a6","article-title":"Surgical management of the burn wound and use of skin substitutes: an expert panel white paper","volume":"34","author":"Kagan","year":"2013","journal-title":"J\u00a0Burn Care Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib72","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/wrr.12119","article-title":"The use of dermal substitutes in burn surgery: acute phase","volume":"22","author":"Shahrokhi","year":"2014","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.jcyt.2014.04.004_bib73","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1111\/j.1365-2133.2007.07914.x","article-title":"The role of fibroblasts in tissue engineering and regeneration","volume":"156","author":"Wong","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/wrr.12120","article-title":"The use of dermal substitutes in burn surgery: acute phase","volume":"22","author":"Greenhalgh","year":"2014","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.jcyt.2014.04.004_bib75","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1098\/rstb.2006.2020","article-title":"Multipotent skin-derived precursors: adult neural crest-related precursors with therapeutic potential","volume":"363","author":"Fernandes","year":"2008","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.jcyt.2014.04.004_bib76","doi-asserted-by":"crossref","unstructured":"Shakhova O, Sommer L. Neural Crest-Derived Stem Cells. StemBook, Cambridge, Massachusetts, USA: Harvard Stem Cell Institute; 2010:2008.","DOI":"10.3824\/stembook.1.51.1"},{"key":"10.1016\/j.jcyt.2014.04.004_bib77","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1242\/dev.127.8.1671","article-title":"Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis","volume":"127","author":"Chai","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.jcyt.2014.04.004_bib78","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1177\/0022034513497961","article-title":"gingivae contain neural-crest- and mesoderm-derived mesenchymal stem cells","volume":"92","author":"Xu","year":"2013","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib79","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.it.2004.11.014","article-title":"A\u00a0stromal address code defined by fibroblasts","volume":"26","author":"Parsonage","year":"2005","journal-title":"Trends Immunol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib80","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/sj.jid.5700986","article-title":"A\u00a0systems biology approach to anatomic diversity of skin","volume":"128","author":"Rinn","year":"2008","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib81","doi-asserted-by":"crossref","first-page":"e119","DOI":"10.1371\/journal.pgen.0020119","article-title":"Anatomic demarcation by positional variation in fibroblast gene expression programs","volume":"2","author":"Rinn","year":"2006","journal-title":"PLoS Genet"},{"key":"10.1016\/j.jcyt.2014.04.004_bib82","doi-asserted-by":"crossref","first-page":"e27097","DOI":"10.1371\/journal.pone.0027097","article-title":"Gingival fibroblasts display reduced adhesion and spreading on extracellular matrix: a possible basis for scarless tissue repair?","volume":"6","author":"Guo","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jcyt.2014.04.004_bib83","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jbiosc.2010.11.014","article-title":"Gingival and dermal fibroblasts: their similarities and differences revealed from gene expression","volume":"111","author":"Ebisawa","year":"2011","journal-title":"J\u00a0Biosci Bioeng"},{"key":"10.1016\/j.jcyt.2014.04.004_bib84","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.ceb.2012.07.001","article-title":"Extracellular matrix, integrins, and growth factors as tailors of the stem cell niche","volume":"24","author":"Brizzi","year":"2012","journal-title":"Curr Opin Cell Biol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib85","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/0003-9969(84)90127-4","article-title":"Biochemistry of glycosaminoglycans in the skin and oral mucosa of the rat","volume":"29","author":"Pedlar","year":"1984","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib86","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1007\/BF02620814","article-title":"Distinctive fibroblastic subpopulations in skin and oral mucosa demonstrated by differences in glycosaminoglycan content","volume":"24","author":"Bronson","year":"1988","journal-title":"In Vitro Cell Dev Biol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib87","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1042\/bj2560035","article-title":"The small dermatan sulphate proteoglycans synthesized by fibroblasts derived from skin, synovium and gingiva show tissue-related heterogeneity","volume":"256","author":"Larjava","year":"1988","journal-title":"Biochem J"},{"key":"10.1016\/j.jcyt.2014.04.004_bib88","first-page":"798","article-title":"Gingival, dermal, and periodontal ligament fibroblasts express different extracellular matrix receptors","volume":"72","author":"Palaiologou","year":"2001","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib89","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1600-0714.1998.tb01952.x","article-title":"Regulation of fibroblast-induced collagen gel contraction by interleukin-1beta","volume":"27","author":"Irwin","year":"1998","journal-title":"J\u00a0Oral Pathol Med"},{"key":"10.1016\/j.jcyt.2014.04.004_bib90","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1177\/00220345980770090801","article-title":"Morphometric studies of collagen and fibrin lattices contracted by human gingival fibroblasts; comparison with dermal fibroblasts","volume":"77","author":"Lorimier","year":"1998","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib91","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00784-001-0143-2","article-title":"Human dermal and gingival fibroblasts in a three-dimensional culture: a comparative study on matrix remodeling","volume":"6","author":"Chaussain Miller","year":"2002","journal-title":"Clin Oral Invest"},{"key":"10.1016\/j.jcyt.2014.04.004_bib92","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1146\/annurev.cellbio.042308.113318","article-title":"Cell motility and mechanics in three-dimensional collagen matrices","volume":"26","author":"Grinnell","year":"2010","journal-title":"Annu Rev Cell Dev Biol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib93","first-page":"8827","article-title":"Migration-stimulating factor: a genetically truncated onco-fetal fibronectin isoform expressed by carcinoma and tumor-associated stromal cells","volume":"63","author":"Schor","year":"2003","journal-title":"Cancer Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib94","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1111\/j.1365-2249.2006.03064.x","article-title":"Cytokines differentially regulate ICAM-1 and VCAM-1 expression on human gingival fibroblasts","volume":"144","author":"Hosokawa","year":"2006","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib95","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1600-0765.2008.01097.x","article-title":"Human leukocyte histocompatibility antigen class II-induced cytokines from human gingival fibroblasts promote proliferation of human umbilical vein endothelial cells: potential association with enhanced angiogenesis in chronic periodontal inflammation","volume":"44","author":"Okada","year":"2009","journal-title":"J\u00a0Periodont Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib96","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1034\/j.1600-0722.2003.00002.x","article-title":"Keratinocyte growth factor and scatter factor expression by regionally defined oral fibroblasts","volume":"111","author":"McKeown","year":"2003","journal-title":"Eur J Oral Sci"},{"key":"10.1016\/j.jcyt.2014.04.004_bib97","first-page":"1072","article-title":"Human skin and gingival keratinocytes show differential regulation of matrix metalloproteinases when combined with fibroblasts in 3-dimensional cultures","volume":"76","author":"Chinnathambi","year":"2005","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib98","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/etp.12007","article-title":"Reepithelialization of wounds","volume":"24","author":"Koivisto","year":"2012","journal-title":"Endodontic Topics"},{"key":"10.1016\/j.jcyt.2014.04.004_bib99","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/BF00923340","article-title":"Bradykinin B1 and B2 receptor agonists synergistically potentiate interleukin-1-induced prostaglandin biosynthesis in human gingival fibroblasts","volume":"15","author":"Lerner","year":"1991","journal-title":"Inflammation"},{"key":"10.1016\/j.jcyt.2014.04.004_bib100","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/0006-2952(96)00417-0","article-title":"Histamine H1 receptor-induced Ca2+ mobilization and prostaglandin E2 release in human gingival fibroblasts: possible role of receptor-operated Ca2+ influx","volume":"52","author":"Niisato","year":"1996","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib101","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1177\/10454411970080010201","article-title":"Lymphocyte-fibroblast interactions","volume":"8","author":"Murakami","year":"1997","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.jcyt.2014.04.004_bib102","first-page":"103","article-title":"Perspective of cytokine regulation for periodontal treatment: fibroblast biology","volume":"74","author":"Takashiba","year":"2003","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib103","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/j.1365-2184.2011.00751.x","article-title":"Paracrine-mediated differentiation and activation of human haematopoietic osteoclast precursor cells by skin and gingival fibroblasts","volume":"44","author":"Costa-Rodrigues","year":"2011","journal-title":"Cell Prolif"},{"key":"10.1016\/j.jcyt.2014.04.004_bib104","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.tips.2013.02.004","article-title":"Missing the target: matrix metalloproteinase antitargets in inflammation and cancer","volume":"34","author":"Dufour","year":"2013","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.jcyt.2014.04.004_bib105","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/jcp.10400","article-title":"Gingival and dermal fibroblasts produce interleukin-1 beta converting enzyme and interleukin-1 beta but not interleukin-18 even after stimulation with lipopolysaccharide","volume":"198","author":"Tardif","year":"2004","journal-title":"J\u00a0Cell Physiol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib106","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1111\/j.1600-0765.2010.01293.x","article-title":"Differential effects of prostaglandin E(2) and enamel matrix derivative on the proliferation of human gingival and dermal fibroblasts and gingival keratinocytes","volume":"45","author":"Weinberg","year":"2010","journal-title":"J\u00a0Periodont Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib107","doi-asserted-by":"crossref","first-page":"15416","DOI":"10.1074\/jbc.M610432200","article-title":"Tissue-specific mechanisms for CCN2\/CTGF persistence in fibrotic gingiva: interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase","volume":"282","author":"Black","year":"2007","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jcyt.2014.04.004_bib108","doi-asserted-by":"crossref","first-page":"e19756","DOI":"10.1371\/journal.pone.0019756","article-title":"Mechanical tension increases CCN2\/CTGF expression and proliferation in gingival fibroblasts via a TGFb-dependent mechanism","volume":"6","author":"Guo","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jcyt.2014.04.004_bib109","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1091\/mbc.e13-08-0451","article-title":"miR-218 regulates focal adhesion kinase-dependent TGF\u03b2 signaling in fibroblasts","volume":"7","author":"Guo","year":"2014","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.jcyt.2014.04.004_bib110","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1002\/jcp.21710","article-title":"Immunomodulatory properties of human periodontal ligament stem cells","volume":"219","author":"Wada","year":"2009","journal-title":"J\u00a0Cell Physiol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib111","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s10875-010-9415-4","article-title":"Human fibroblasts share immunosuppressive properties with bone marrow mesenchymal stem cells","volume":"30","author":"Cappellesso-Fleury","year":"2010","journal-title":"J\u00a0Clin Immunol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib112","doi-asserted-by":"crossref","first-page":"e70937","DOI":"10.1371\/journal.pone.0070937","article-title":"Inhibition of the differentiation of monocyte-derived dendritic cells by human gingival fibroblasts","volume":"8","author":"S\u00e9guier","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jcyt.2014.04.004_bib113","first-page":"344","article-title":"Interferon-gamma-dependent immunosuppressive effects of human gingival fibroblasts","volume":"76","author":"Shimabukuro","year":"1992","journal-title":"Immunology"},{"key":"10.1016\/j.jcyt.2014.04.004_bib114","first-page":"230","article-title":"Role of cytokine in the induction of adhesion molecules on cultured human gingival fibroblasts","volume":"65","author":"Takahashi","year":"1994","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib115","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1600-0765.1996.tb00486.x","article-title":"Antigen-presenting-cell function of interferon gamma-treated human gingival fibroblasts","volume":"31","author":"Shimabukuro","year":"1996","journal-title":"J\u00a0Periodont Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib116","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.4049\/jimmunol.178.2.1151","article-title":"IL-8 and IDO expression by human gingival fibroblasts via TLRs","volume":"178","author":"Mahanonda","year":"2007","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib117","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1161\/ATVBAHA.107.140640","article-title":"Preservation of rabbit aorta elastin from degradation by gingival fibroblasts in an ex vivo model","volume":"27","author":"Gogly","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib118","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1161\/ATVBAHA.112.251439","article-title":"Endoluminal gingival fibroblast transfer reduces the size of rabbit carotid aneurisms via elastin repair","volume":"32","author":"Durand","year":"2012","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib119","doi-asserted-by":"crossref","first-page":"5100","DOI":"10.1016\/j.biomaterials.2007.07.031","article-title":"Bioengineering skin using mechanisms of regeneration and repair","volume":"28","author":"Metcalfe","year":"2007","journal-title":"Biomaterials"},{"key":"10.1016\/j.jcyt.2014.04.004_bib120","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1038\/jid.2008.78","article-title":"Potential of fibroblast cell therapy for recessive dystrophic epidermolysis bullosa","volume":"128","author":"Wong","year":"2008","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib121","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/PRS.0b013e318254b1ea","article-title":"A\u00a0systematic review of skin substitutes for foot ulcers","volume":"130","author":"Felder","year":"2012","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib122","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jaad.2011.08.035","article-title":"Cutaneous scarring: pathophysiology, molecular mechanisms, and scar reduction therapeutics, part II: strategies to reduce scar formation after dermatologic procedures","volume":"66","author":"Tziotzios","year":"2012","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib123","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1600-0765.1968.tb01908.x","article-title":"Microscopic evaluation of the healing and revascularization of free gingival grafts","volume":"3","author":"Oliver","year":"1968","journal-title":"J\u00a0Periodont Res"},{"key":"10.1016\/j.jcyt.2014.04.004_bib124","first-page":"470","article-title":"Histological evaluation of healing and revascularization of the subepithelial connective tissue graft","volume":"72","author":"Guiha","year":"2001","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib125","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/00006534-198509000-00013","article-title":"Palatal grafts for eyelid reconstruction","volume":"76","author":"Siegel","year":"1985","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib126","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/j.1442-9071.2008.01697.x","article-title":"Cicatricial entropion repair with hard palate mucous membrane graft: surgical technique and outcomes","volume":"36","author":"Swamy","year":"2008","journal-title":"Clin Exp Ophthalmol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib127","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/0002-9394(89)90257-2","article-title":"Posterior lamellar eyelid reconstruction with a hard palate mucosal graft","volume":"107","author":"Bartley","year":"1989","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib128","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S1010-5182(05)80250-1","article-title":"Use of the palatal mucosal graft for reconstruction of the eye socket","volume":"23","author":"Yoshimura","year":"1995","journal-title":"J\u00a0Craniomaxillofac Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib129","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.bjps.2008.05.040","article-title":"Full-thickness reconstruction of the eyelid with rotation flap based on orbicularis oculi muscle and palatal mucosal graft: long-term results in 12 cases","volume":"62","author":"Miyamoto","year":"2009","journal-title":"J\u00a0Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib130","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1097\/01.SAP.0000068115.91989.A4","article-title":"Usefulness of palatal mucoperiosteal grafts for artificial eye socket contracture","volume":"51","author":"Ito","year":"2003","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib131","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/IOP.0b013e318050d2d1","article-title":"Eyelid mucous membrane grafts: a histologic study of hard palate, nasal turbinate, and buccal mucosal grafts","volume":"23","author":"Weinberg","year":"2007","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib132","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S1010-5182(05)80200-8","article-title":"Secondary correction of bilateral cleft lip nose deformity","volume":"18","author":"Nakajima","year":"1990","journal-title":"J\u00a0Craniomaxillofac Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib133","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1097\/00006534-199009000-00030","article-title":"Tracheoplasty with palatal mucoperiosteal graft","volume":"86","author":"Yoshimura","year":"1990","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib134","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/bjs.18002911312","article-title":"one-stage operation for hypospadias","volume":"29","author":"Humby","year":"1941","journal-title":"Br J Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib135","first-page":"662","article-title":"The buccal mucosal graft for urethral reconstruction: a preliminary report","volume":"147","author":"Burger","year":"1992","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib136","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.urology.2004.05.011","article-title":"Long-term outcome of ventral buccal mucosa onlay graft urethroplasty for urethral stricture repair","volume":"64","author":"Fichtner","year":"2004","journal-title":"Urology"},{"key":"10.1016\/j.jcyt.2014.04.004_bib137","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1111\/j.1464-410X.2003.04860.x","article-title":"Buccal mucosal urethroplasty: is it the new gold standard?","volume":"93","author":"Bhargava","year":"2004","journal-title":"BJU Int"},{"key":"10.1016\/j.jcyt.2014.04.004_bib138","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1046\/j.1464-410x.1999.00079.x","article-title":"The histology and immunohistochemistry of free buccal mucosa and full-skin grafts after exposure to urine","volume":"84","author":"Filipas","year":"1999","journal-title":"BJU Int"},{"key":"10.1016\/j.jcyt.2014.04.004_bib139","first-page":"1970","article-title":"Long-term followup of buccal mucosa onlay graft for hypospadias repair: analysis of complications","volume":"172","author":"Fichtner","year":"2004","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib140","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.joms.2007.11.023","article-title":"Morbidity associated with oral mucosa harvest for urological reconstruction: an overview","volume":"66","author":"Markiewicz","year":"2008","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib141","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1038\/jid.2011.85","article-title":"HB-EGF induces COL7A1 expression in keratinocytes and fibroblasts: possible mechanism underlying allogeneic fibroblast therapy in recessive dystrophic epidermolysis Bullosa","volume":"131","author":"Nagy","year":"2011","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib142","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1038\/jid.2011.125","article-title":"Cell-based therapy for RDEB: how does it work?","volume":"131","author":"Uitto","year":"2011","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib143","first-page":"263","article-title":"Autologous cultured fibroblast injection for facial contour deformities: a prospective, placebo-controlled, Phase III clinical trial","volume":"33","author":"Weiss","year":"2007","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.jcyt.2014.04.004_bib144","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s10047-008-0428-1","article-title":"Comparative evaluation of re-epithelialization promoted by fresh or cryopreserved cultured dermal substitute","volume":"11","author":"Yamada","year":"2008","journal-title":"J\u00a0Artif Organs"},{"key":"10.1016\/j.jcyt.2014.04.004_bib145","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1089\/ten.2004.10.1180","article-title":"Survival of Apligraf in acute human wounds","volume":"10","author":"Griffiths","year":"2004","journal-title":"Tissue Eng"},{"key":"10.1016\/j.jcyt.2014.04.004_bib146","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1046\/j.1524-475X.2002.10901.x","article-title":"Allogeneic fibroblasts in dermal substitutes induce inflammation and scar formation","volume":"10","author":"Lamme","year":"2002","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.jcyt.2014.04.004_bib147","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1089\/ten.tea.2010.0680","article-title":"Three-dimensional fibroblast cultures stimulate improved ventricular performance in chronically ischemic canine hearts","volume":"17","author":"Kellar","year":"2011","journal-title":"Tissue Eng Part A"},{"key":"10.1016\/j.jcyt.2014.04.004_bib148","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1177\/0363546510387095","article-title":"Skin-derived tenocyte-like cells for the treatment of patellar tendinopathy","volume":"39","author":"Clarke","year":"2011","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.jcyt.2014.04.004_bib149","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1136\/ard.2010.143297","article-title":"Skin fibroblasts are potent suppressors of inflammation in experimental arthritis","volume":"70","author":"Bouffi","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jcyt.2014.04.004_bib150","first-page":"867","article-title":"Evaluation of the safety and efficacy of periodontal applications of a living tissue-engineered human fibroblast-derived dermal substitute, I: comparison to the gingival autograft: a randomized controlled pilot study","volume":"76","author":"McGuire","year":"2005","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib151","first-page":"1847","article-title":"A\u00a0pilot study to evaluate a tissue-engineered bilayered cell therapy as an alternative to tissue from the palate","volume":"79","author":"McGuire","year":"2008","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib152","first-page":"151","article-title":"The clinical efficacy of DynaMatrix extracellular membrane in augmenting keratinized tissue","volume":"30","author":"Nevins","year":"2010","journal-title":"Int J Periodon Restorative Dent"},{"key":"10.1016\/j.jcyt.2014.04.004_bib153","first-page":"31","article-title":"Tissue-engineered bilayered cell therapy for the treatment of oral mucosal defects: a case series","volume":"30","author":"Nevins","year":"2010","journal-title":"Int J Periodon Restorative Dent"},{"key":"10.1016\/j.jcyt.2014.04.004_bib154","first-page":"1414","article-title":"Living Cellular Construct for Increasing the Width of Keratinized Gingiva: results from a randomized, within-patient, controlled trial","volume":"82","author":"McGuire","year":"2011","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib155","first-page":"e57","article-title":"Generation of site-appropriate tissue by a living cellular sheet in the treatment of mucogingival defects","volume":"85","author":"Scheyer","year":"2013","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib156","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1177\/0022034511435702","article-title":"Tissue-engineered oral mucosa","volume":"91","author":"Moharamzadeh","year":"2012","journal-title":"J\u00a0Dent Re"},{"key":"10.1016\/j.jcyt.2014.04.004_bib157","first-page":"262","article-title":"An autologous cell hyaluronic acid graft technique for gingival augmentation: a case series","volume":"74","author":"Prato","year":"2003","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib158","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1902\/jop.2007.060105","article-title":"A\u00a0randomized, double-blind, placebo-controlled study to determine the safety and efficacy of cultured and expanded autologous fibroblast injections for the treatment of interdental papillary insufficiency associated with the papilla priming procedure","volume":"78","author":"McGuire","year":"2007","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib159","first-page":"616","article-title":"Acellular dermal matrix seeded with autologous gingival fibroblasts for the treatment of gingival recession: a proof-of-concept study","volume":"81","author":"Jhaveri","year":"2010","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib160","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.aanat.2012.03.011","article-title":"The clinical efficacy of primary culture of human fibroblasts in gingival augmentation procedures: a preliminary report","volume":"194","author":"Dominiak","year":"2012","journal-title":"Ann Anat"},{"key":"10.1016\/j.jcyt.2014.04.004_bib161","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1002\/lary.21417","article-title":"Injection of cultured autologous fibroblasts for human vocal fold scars","volume":"121","author":"Chhetri","year":"2011","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jcyt.2014.04.004_bib162","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.eururo.2008.01.061","article-title":"Tissue-engineered buccal mucosa urethroplasty-clinical outcomes","volume":"53","author":"Bhargava","year":"2008","journal-title":"Eur Urol"},{"key":"10.1016\/j.jcyt.2014.04.004_bib163","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1089\/ten.2007.0008","article-title":"Potential of heterotopic fibroblasts as autologous transplanted cells for tracheal epithelial regeneration","volume":"13","author":"Kobayashi","year":"2007","journal-title":"Tissue Eng"},{"key":"10.1016\/j.jcyt.2014.04.004_bib164","doi-asserted-by":"crossref","first-page":"4855","DOI":"10.1016\/j.biomaterials.2010.02.027","article-title":"A\u00a0tissue-engineered trachea derived from a framed collagen scaffold, gingival fibroblasts and adipose-derived stem cells","volume":"31","author":"Kobayashi","year":"2010","journal-title":"Biomaterials"}],"container-title":["Cytotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1465324914005611?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1465324914005611?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T22:20:08Z","timestamp":1761430808000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1465324914005611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":164,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S1465324914005611"],"URL":"https:\/\/doi.org\/10.1016\/j.jcyt.2014.04.004","relation":{},"ISSN":["1465-3249"],"issn-type":[{"value":"1465-3249","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distinct phenotype and therapeutic potential of gingival fibroblasts","name":"articletitle","label":"Article Title"},{"value":"Cytotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcyt.2014.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}