{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T17:09:32Z","timestamp":1782407372988,"version":"3.54.5"},"reference-count":22,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["celltherapyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytotherapy"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.jcyt.2018.03.040","type":"journal-article","created":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T09:24:29Z","timestamp":1525857869000},"page":"830-838","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Multicenter phase 1\/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation"],"prefix":"10.1016","volume":"20","author":[{"given":"Winnie","family":"Ip","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana M.F.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Gaspar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arindam","family":"Mitra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreenal","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanchan","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Chiesa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Persis","family":"Amrolia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Gilmour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gul","family":"Ahsan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Slatter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew R.","family":"Gennery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert F.","family":"Wynn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Veys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waseem","family":"Qasim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcyt.2018.03.040_bib0010","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0002-9343(97)00015-6","article-title":"Adenovirus infections in immunocompromised patients","volume":"102","author":"Carrigan","year":"1997","journal-title":"Am J Med"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0015","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1038\/sj.bmt.1701563","article-title":"Adenovirus infection after pediatric bone marrow transplantation","volume":"23","author":"Hale","year":"1999","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0020","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/j.1365-2141.2005.05649.x","article-title":"Improved outcome for children with disseminated adenoviral infection following allogeneic stem cell transplantation","volume":"130","author":"Kampmann","year":"2005","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0025","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1182\/blood-2002-07-2152","article-title":"Molecular monitoring of adenovirus in peripheral blood after allogeneic bone marrow transplantation permits early diagnosis of disseminated disease","volume":"102","author":"Lion","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0030","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1182\/blood-2002-02-0377","article-title":"Adenovirus infections following allogeneic stem cell transplantation: incidence and outcome in relation to graft manipulation, immunosuppression, and immune recovery","volume":"100","author":"Chakrabarti","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0035","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1038\/bmt.2012.221","article-title":"Impact of viral reactivations in the era of pre-emptive antiviral drug therapy following allogeneic haematopoietic SCT in paediatric recipients","volume":"48","author":"Hiwarkar","year":"2013","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0040","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1086\/427513","article-title":"Immune reconstitution and clearance of human adenovirus viremia in pediatric stem-cell recipients","volume":"191","author":"Heemskerk","year":"2005","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0045","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1365-2141.2004.05331.x","article-title":"Detection of adenovirus-specific T cells in children with adenovirus infection after allogeneic stem cell transplantation","volume":"128","author":"Feuchtinger","year":"2005","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0050","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1182\/blood.V97.2.388","article-title":"Cidofovir for cytomegalovirus infection and disease in allogeneic stem cell transplant recipients. The Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation","volume":"97","author":"Ljungman","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0055","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/sj.bmt.1703798","article-title":"Cidofovir for adenovirus infections after allogeneic hematopoietic stem cell transplantation: a survey by the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation","volume":"31","author":"Ljungman","year":"2003","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0060","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1182\/blood-2003-07-2449","article-title":"Fiber-modified adenoviruses generate subgroup cross-reactive, adenovirus-specific cytotoxic T lymphocytes for therapeutic applications","volume":"103","author":"Leen","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0065","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1038\/nm1475","article-title":"Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals","volume":"12","author":"Leen","year":"2006","journal-title":"Nat Med"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0070","doi-asserted-by":"crossref","first-page":"4283","DOI":"10.1182\/blood-2009-07-232454","article-title":"Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation","volume":"114","author":"Leen","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0075","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.exphem.2003.12.009","article-title":"Isolation and expansion of human adenovirus-specific CD4+ and CD8+ T cells according to IFN-gamma secretion for adjuvant immunotherapy","volume":"32","author":"Feuchtinger","year":"2004","journal-title":"Exp Hematol"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0080","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1182\/blood-2014-06-573725","article-title":"Adoptive T-cell therapy with hexon-specific Th1 cells as a treatment of refractory adenovirus infection after HSCT","volume":"125","author":"Feucht","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0085","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/bjh.12251","article-title":"Interferon-gamma capture T cell therapy for persistent Adenoviraemia following allogeneic haematopoietic stem cell transplantation","volume":"161","author":"Qasim","year":"2013","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0090","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/j.jcyt.2016.06.009","article-title":"Manufacture of GMP-compliant functional adenovirus-specific T-cell therapy for treatment of post-transplant infectious complications","volume":"18","author":"Horlock","year":"2016","journal-title":"Cytotherapy"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0095","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/sj.bmt.1703883","article-title":"Factors predicting response and graft-versus-host disease after donor lymphocyte infusions: a study on 593 infusions","volume":"31","author":"Raiola","year":"2003","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0100","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s10875-015-0135-7","article-title":"Variable phenotype of severe immunodeficiencies associated with RMRP gene mutations","volume":"35","author":"Ip","year":"2015","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0105","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1093\/cid\/ciu940","article-title":"Astrovirus VA1\/HMO-C: an increasingly recognized neurotropic pathogen in immunocompromised patients","volume":"60","author":"Brown","year":"2015","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0110","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/CJI.0000000000000034","article-title":"First-in-man clinical results with Good Manufacturing Practice (GMP)-compliant polypeptide-expanded adenovirus-specific T cells after haploidentical hematopoietic stem cell transplantation","volume":"37","author":"Geyeregger","year":"2014","journal-title":"J Immunother"},{"key":"10.1016\/j.jcyt.2018.03.040_bib0115","doi-asserted-by":"crossref","first-page":"5113","DOI":"10.1182\/blood-2013-02-486324","article-title":"Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation","volume":"121","author":"Leen","year":"2013","journal-title":"Blood"}],"container-title":["Cytotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1465324918304845?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1465324918304845?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T01:36:09Z","timestamp":1761442569000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1465324918304845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S1465324918304845"],"URL":"https:\/\/doi.org\/10.1016\/j.jcyt.2018.03.040","relation":{},"ISSN":["1465-3249"],"issn-type":[{"value":"1465-3249","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multicenter phase 1\/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation","name":"articletitle","label":"Article Title"},{"value":"Cytotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcyt.2018.03.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2018 Published by Elsevier Inc. on behalf of International Society for Cellular Therapy. All rights reserved.","name":"copyright","label":"Copyright"}]}}