{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T01:32:43Z","timestamp":1790386363200,"version":"4.1.0"},"reference-count":9,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T00:00:00Z","timestamp":1575504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["jaadcasereports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JAAD Case Reports"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.jdcr.2019.12.002","type":"journal-article","created":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T20:02:35Z","timestamp":1579896155000},"page":"139-140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Alcohol-induced facial flushing in a patient with atopic dermatitis treated with dupilumab"],"prefix":"10.1016","volume":"6","author":[{"given":"Sean J.","family":"Igelman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanho","family":"Na","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric L.","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdcr.2019.12.002_bib1","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1056\/NEJMoa1610020","article-title":"Two phase 3 trials of dupilumab versus placebo in atopic dermatitis","volume":"375","author":"Simpson","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jdcr.2019.12.002_bib2","doi-asserted-by":"crossref","first-page":"e12762","DOI":"10.1111\/dth.12762","article-title":"New alcohol flushing in a patient with atopic dermatitis under therapy with dupilumab","volume":"32","author":"Herz","year":"2019","journal-title":"Dermatol Ther"},{"issue":"5","key":"10.1016\/j.jdcr.2019.12.002_bib3","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.revmed.2013.08.015","article-title":"Causes and differential diagnosis of flush","volume":"35","author":"Lafont","year":"2014","journal-title":"Rev Med Interne"},{"key":"10.1016\/j.jdcr.2019.12.002_bib4","series-title":"Dupixent (dupilumab) [package insert]","year":"2017"},{"key":"10.1016\/j.jdcr.2019.12.002_bib5","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-3-319-98788-0_2","article-title":"Roles of cytochrome P450 in metabolism of ethanol and carcinogens","volume":"1032","author":"Peter Guengerich","year":"2018","journal-title":"Adv Exp Med Biol"},{"issue":"4","key":"10.1016\/j.jdcr.2019.12.002_bib6","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.cld.2012.08.002","article-title":"Alcohol metabolism","volume":"16","author":"Cederbaum","year":"2012","journal-title":"Clin Liver Dis"},{"issue":"12","key":"10.1016\/j.jdcr.2019.12.002_bib7","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1001\/archderm.140.12.1542-b","article-title":"Alcohol intolerance and facial flushing in patient treated with topical tacrolimus","volume":"140","author":"Milingou","year":"2004","journal-title":"Arch Dermatol"},{"issue":"3","key":"10.1016\/j.jdcr.2019.12.002_bib8","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S1081-1206(10)61227-6","article-title":"Alcohol-induced rash caused by topical tacrolimus","volume":"95","author":"Knight","year":"2005","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"8","key":"10.1016\/j.jdcr.2019.12.002_bib9","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1001\/archderm.140.8.1014","article-title":"Alcohol-induced application site erythema after topical immunomodulator use and its inhibition by aspirin","volume":"140","author":"Ehst","year":"2004","journal-title":"Arch Dermatol"}],"container-title":["JAAD Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352512619307234?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352512619307234?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:21:06Z","timestamp":1762474866000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352512619307234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S2352512619307234"],"URL":"https:\/\/doi.org\/10.1016\/j.jdcr.2019.12.002","relation":{},"ISSN":["2352-5126"],"issn-type":[{"value":"2352-5126","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alcohol-induced facial flushing in a patient with atopic dermatitis treated with dupilumab","name":"articletitle","label":"Article Title"},{"value":"JAAD Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdcr.2019.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the American Academy of Dermatology, Inc. Published by Elsevier, Inc.","name":"copyright","label":"Copyright"}]}}