{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:38:13Z","timestamp":1789749493677,"version":"4.0.1"},"reference-count":8,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T00:00:00Z","timestamp":1638489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["jaadcasereports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JAAD Case Reports"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.jdcr.2021.11.030","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T12:26:23Z","timestamp":1641471983000},"page":"38-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Modified dose of guselkumab for treatment of pyoderma gangrenosum"],"prefix":"10.1016","volume":"21","author":[{"given":"Ashley M.","family":"Reese","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Erickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine B.","family":"Reed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex G.","family":"Ortega-Loayza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.jdcr.2021.11.030_bib1","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1001\/archdermatol.2011.168","article-title":"Interleukin 23 expression in pyoderma gangrenosum and targeted therapy with ustekinumab","volume":"147","author":"Guenova","year":"2011","journal-title":"Arch Dermatol"},{"issue":"3","key":"10.1016\/j.jdcr.2021.11.030_bib2","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s40257-017-0251-7","article-title":"Pyoderma gangrenosum: an update on pathophysiology, diagnosis and treatment","volume":"18","author":"Alavi","year":"2017","journal-title":"Am J Clin Dermatol"},{"issue":"9","key":"10.1016\/j.jdcr.2021.11.030_bib3","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/s41569-021-00552-1","article-title":"Interplay between inflammation and thrombosis in cardiovascular pathology","volume":"18","author":"Stark","year":"2021","journal-title":"Nat Rev Cardiol"},{"issue":"3","key":"10.1016\/j.jdcr.2021.11.030_bib4","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/j.1440-0960.2011.00750.x","article-title":"Pyoderma gangrenosum requiring inpatient management: A report of 26 cases with follow up","volume":"52","author":"Saracino","year":"2011","journal-title":"Australas J Dermatol"},{"key":"10.1016\/j.jdcr.2021.11.030_bib5","doi-asserted-by":"crossref","unstructured":"Westerdahl JS, Nusbaum KB, Chung CG, Kaffenberger BH, Ortega-Loayza AG. Ustekinumab as adjuvant treatment for all pyoderma gangrenosum subtypes. J Dermatolog Treat. Published online June 14, 2021. https:\/\/doi.org\/10.1080\/09546634.2021.1937475","DOI":"10.1080\/09546634.2021.1937475"},{"issue":"4","key":"10.1016\/j.jdcr.2021.11.030_bib6","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1111\/iwj.13359","article-title":"Successful treatment of a refractory pyoderma gangrenosum with risankizumab","volume":"17","author":"Burgdorf","year":"2020","journal-title":"Int Wound J"},{"issue":"6","key":"10.1016\/j.jdcr.2021.11.030_bib7","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1097\/01.ASW.0000744324.59877.df","article-title":"Peristomal pyoderma gangrenosum responding to risankizumab","volume":"34","author":"Weigelt","year":"2021","journal-title":"Adv Skin Wound Care"},{"key":"10.1016\/j.jdcr.2021.11.030_bib8","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jdcr.2020.12.005","article-title":"Guselkumab as a treatment option for recalcitrant pyoderma gangrenosum","volume":"8","author":"Baier","year":"2021","journal-title":"JAAD Case Rep"}],"container-title":["JAAD Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235251262100895X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235251262100895X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:23:58Z","timestamp":1762475038000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S235251262100895X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":8,"alternative-id":["S235251262100895X"],"URL":"https:\/\/doi.org\/10.1016\/j.jdcr.2021.11.030","relation":{},"ISSN":["2352-5126"],"issn-type":[{"value":"2352-5126","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Modified dose of guselkumab for treatment of pyoderma gangrenosum","name":"articletitle","label":"Article Title"},{"value":"JAAD Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdcr.2021.11.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 by the American Academy of Dermatology, Inc. Published by Elsevier, Inc.","name":"copyright","label":"Copyright"}]}}