{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:58:28Z","timestamp":1791471508235,"version":"4.3.4"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T00:00:00Z","timestamp":1666656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jaadcasereports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JAAD Case Reports"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.jdcr.2022.10.019","type":"journal-article","created":{"date-parts":[[2022,10,29]],"date-time":"2022-10-29T22:46:53Z","timestamp":1667083613000},"page":"108-110","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Rapid resolution of widespread cutaneous lichen planus and generalized pruritus in an elderly patient following treatment with dupilumab"],"prefix":"10.1016","volume":"30","author":[{"given":"Soroush","family":"Kazemi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan","family":"Murphrey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason E.","family":"Hawkes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdcr.2022.10.019_bib1","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1056\/NEJMcp1103641","article-title":"Clinical practice. Lichen planus","volume":"366","author":"Le Cleach","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jdcr.2022.10.019_bib2","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.jaad.2018.02.010","article-title":"Lichen planus and lichenoid dermatoses: clinical overview and molecular basis","volume":"79","author":"Tziotzios","year":"2018","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jdcr.2022.10.019_bib3","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/exd.14226","article-title":"The inflammation in cutaneous lichen planus is dominated by IFN-upsilon and IL-21-A basis for therapeutic JAK1 inhibition","volume":"30","author":"Pietschke","year":"2021","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jdcr.2022.10.019_bib4","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aav7561","article-title":"IFN-gamma enhances cell-mediated cytotoxicity against keratinocytes via JAK2\/STAT1 in lichen planus","volume":"11","author":"Shao","year":"2019","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jdcr.2022.10.019_bib5","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nrd4624","article-title":"Targeting key proximal drivers of type 2 inflammation in disease","volume":"15","author":"Gandhi","year":"2016","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.jdcr.2022.10.019_bib6","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jdcr.2021.10.005","article-title":"Simultaneous treatment of Samter triad and prurigo nodularis with dupilumab","volume":"18","author":"Bloomstein","year":"2021","journal-title":"JAAD Case Rep"},{"key":"10.1016\/j.jdcr.2022.10.019_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0173017","article-title":"Myeloid dendritic cells stimulated by thymic stromal lymphopoietin promote Th2 immune responses and the pathogenesis of oral lichen planus","volume":"12","author":"Yamauchi","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jdcr.2022.10.019_bib8","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.archoralbio.2018.11.015","article-title":"IL-25 promotes Th2-type reactions and correlates with disease severity in the pathogenesis of oral lichen planus","volume":"98","author":"Wang","year":"2019","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.jdcr.2022.10.019_bib9","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1080\/17512433.2018.1449642","article-title":"Dupilumab for treatment of atopic dermatitis","volume":"11","author":"Seegraber","year":"2018","journal-title":"Expert Rev Clin Pharmacol"},{"issue":"3","key":"10.1016\/j.jdcr.2022.10.019_bib10","first-page":"72","article-title":"Chronic pruritus responding to dupilumab-A case series","volume":"6","author":"Zhai","year":"2019","journal-title":"Medicines (Basel)"}],"container-title":["JAAD Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352512622004763?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352512622004763?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:24:42Z","timestamp":1762475082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352512622004763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":10,"alternative-id":["S2352512622004763"],"URL":"https:\/\/doi.org\/10.1016\/j.jdcr.2022.10.019","relation":{},"ISSN":["2352-5126"],"issn-type":[{"value":"2352-5126","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rapid resolution of widespread cutaneous lichen planus and generalized pruritus in an elderly patient following treatment with dupilumab","name":"articletitle","label":"Article Title"},{"value":"JAAD Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdcr.2022.10.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier on behalf of the American Academy of Dermatology, Inc. This is an open access..","name":"copyright","label":"Copyright"}]}}