{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T15:58:06Z","timestamp":1770479886082,"version":"3.49.0"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T00:00:00Z","timestamp":1759536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jaadcasereports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JAAD Case Reports"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jdcr.2025.09.030","type":"journal-article","created":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:22:51Z","timestamp":1760142171000},"page":"164-168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Novel isochromosome 7q and NOTCH1 mutation in an 88-year-old male with S\u00e9zary syndrome"],"prefix":"10.1016","volume":"66","author":[{"given":"Nicole","family":"Loranger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Trepanowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremiah X.","family":"Karrs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7785-2899","authenticated-orcid":false,"given":"Wahab A.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parth","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joi B.","family":"Carter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick","family":"Lansigan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jdcr.2025.09.030_bib1","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1182\/blood-2007-03-055749","volume":"110","author":"Olsen","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.jdcr.2025.09.030_bib2","article-title":"Integrated genomic analysis of S\u00e9zary syndrome","volume":"2011","author":"Mao","year":"2011","journal-title":"Genet Res Int"},{"issue":"12","key":"10.1016\/j.jdcr.2025.09.030_bib3","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1038\/ng.3442","article-title":"The mutational landscape of cutaneous T cell lymphoma and S\u00e9zary syndrome","volume":"47","author":"Da Silva Almeida","year":"2015","journal-title":"Nat Genet"},{"issue":"5","key":"10.1016\/j.jdcr.2025.09.030_bib4","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1111\/j.1365-2133.2010.09973.x","article-title":"Novel approach to gene expression profiling in S\u00e9zary syndrome: genomic profiling in S\u00e9zary syndrome","volume":"163","author":"Pomerantz","year":"2010","journal-title":"Br J Dermatol"},{"issue":"4","key":"10.1016\/j.jdcr.2025.09.030_bib5","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1182\/blood-2002-08-2434","article-title":"Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas","volume":"101","author":"Mao","year":"2003","journal-title":"Blood"},{"issue":"7","key":"10.1016\/j.jdcr.2025.09.030_bib6","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1016\/j.jid.2016.03.024","article-title":"Identification of gene mutations and fusion genes in patients with S\u00e9zary syndrome","volume":"136","author":"Prasad","year":"2016","journal-title":"J Invest Dermatol"},{"issue":"Supplement 1","key":"10.1016\/j.jdcr.2025.09.030_bib7","doi-asserted-by":"crossref","first-page":"4440","DOI":"10.1182\/blood-2024-205144","article-title":"Gene copy number alterations identify subsets of mycosis Fungoides\/S\u00e9zary syndrome patients with worse survival outcomes","volume":"144","author":"Kiwan","year":"2024","journal-title":"Blood"},{"issue":"18","key":"10.1016\/j.jdcr.2025.09.030_bib8","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1182\/blood.2019004118","article-title":"Hepatosplenic T-cell lymphoma: a rare but challenging entity","volume":"136","author":"Pro","year":"2020","journal-title":"Blood"},{"issue":"14","key":"10.1016\/j.jdcr.2025.09.030_bib9","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.1182\/blood-2009-12-260216","article-title":"Notch1 as a potential therapeutic target in cutaneous T-cell lymphoma","volume":"116","author":"Kamstrup","year":"2010","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.jdcr.2025.09.030_bib10","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.jmoldx.2016.10.002","article-title":"Standards and guidelines for the interpretation and reporting of sequence variants in cancer","volume":"19","author":"Li","year":"2017","journal-title":"J Mol Diagn"}],"container-title":["JAAD Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352512625005107?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352512625005107?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T20:18:26Z","timestamp":1770409106000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352512625005107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":10,"alternative-id":["S2352512625005107"],"URL":"https:\/\/doi.org\/10.1016\/j.jdcr.2025.09.030","relation":{},"ISSN":["2352-5126"],"issn-type":[{"value":"2352-5126","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel isochromosome 7q and NOTCH1 mutation in an 88-year-old male with S\u00e9zary syndrome","name":"articletitle","label":"Article Title"},{"value":"JAAD Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdcr.2025.09.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc. on behalf of the American Academy of Dermatology, Inc.","name":"copyright","label":"Copyright"}]}}