{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T08:03:16Z","timestamp":1770710596220,"version":"3.49.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"am","delay-in-days":277,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000057","name":"NIH National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["2P20 GM109024"],"award-info":[{"award-number":["2P20 GM109024"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Drug Delivery Science and Technology"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jddst.2025.107341","type":"journal-article","created":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:57:29Z","timestamp":1753891049000},"page":"107341","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Panobinostat-loaded albumin nanoparticles for the treatment of pancreatic cancer"],"prefix":"10.1016","volume":"113","author":[{"given":"Paras Mani","family":"Giri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1799-627X","authenticated-orcid":false,"given":"Arpita","family":"Ghosal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Travis","family":"Kruse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Buddhadev","family":"Layek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.jddst.2025.107341_bib2","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics15092363","article-title":"Advances in pancreatic cancer treatment by nano-based drug delivery systems","volume":"15","author":"Viegas","year":"2023","journal-title":"Pharmaceutics"},{"issue":"11","key":"10.1016\/j.jddst.2025.107341_bib3","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1016\/j.clinthera.2017.08.015","article-title":"Current standards of chemotherapy for pancreatic cancer","volume":"39","author":"Saung","year":"2017","journal-title":"Clin. Ther."},{"key":"10.1016\/j.jddst.2025.107341_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116743","article-title":"Nanocarrier mediated entinostat and oxaliplatin combination therapy displayed enhanced efficacy against pancreatic cancer","volume":"175","author":"Giri","year":"2024","journal-title":"Biomed. Pharmacother."},{"issue":"19","key":"10.1016\/j.jddst.2025.107341_bib5","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1056\/NEJMoa1011923","article-title":"FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer","volume":"364","author":"Conroy","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jddst.2025.107341_bib6","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.actbio.2023.02.038","article-title":"Sono-promoted drug penetration and extracellular matrix modulation potentiate sonodynamic therapy of pancreatic ductal adenocarcinoma","volume":"161","author":"Xiao","year":"2023","journal-title":"Acta Biomater."},{"issue":"7","key":"10.1016\/j.jddst.2025.107341_bib7","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1517\/14728222.2011.566216","article-title":"Overcoming drug resistance in pancreatic cancer","volume":"15","author":"Long","year":"2011","journal-title":"Expert Opin. Ther. Targets"},{"issue":"18","key":"10.1016\/j.jddst.2025.107341_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20184504","article-title":"Chemoresistance in pancreatic cancer","volume":"20","author":"Zeng","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jddst.2025.107341_bib9","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.critrevonc.2017.03.026","article-title":"Drug resistance in pancreatic cancer: impact of altered energy metabolism","volume":"114","author":"Grasso","year":"2017","journal-title":"Crit. Rev. Oncol. Hematol."},{"key":"10.1016\/j.jddst.2025.107341_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2024.124753","article-title":"Mesenchymal stem cell-delivered paclitaxel nanoparticles exhibit enhanced efficacy against a syngeneic orthotopic mouse model of pancreatic cancer","volume":"666","author":"Mani Giri","year":"2024","journal-title":"Int. J. Pharm."},{"issue":"12","key":"10.1016\/j.jddst.2025.107341_bib11","doi-asserted-by":"crossref","first-page":"4577","DOI":"10.1111\/bcp.14889","article-title":"Recent developments of HDAC inhibitors: emerging indications and novel molecules","volume":"87","author":"Bondarev","year":"2021","journal-title":"Br. J. Clin. Pharmacol."},{"issue":"7","key":"10.1016\/j.jddst.2025.107341_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18071414","article-title":"Histone deacetylase inhibitors as anticancer drugs","volume":"18","author":"Eckschlager","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"21","key":"10.1016\/j.jddst.2025.107341_bib13","first-page":"3372","article-title":"Recent histone deacetylase inhibitors in cancer therapy","volume":"129","author":"Parveen","year":"2023"},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib14","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s13148-023-01531-8","article-title":"Update on histone deacetylase inhibitors in peripheral T-cell lymphoma (PTCL)","volume":"15","author":"Lu","year":"2023","journal-title":"Clin. Epigenet."},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib15","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s13045-024-01551-8","article-title":"Advances in targeting histone deacetylase for treatment of solid tumors","volume":"17","author":"Shi","year":"2024","journal-title":"J. Hematol. Oncol."},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib16","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s40487-016-0023-1","article-title":"Panobinostat as pan-deacetylase inhibitor for the treatment of pancreatic cancer: recent progress and future prospects","volume":"4","author":"Singh","year":"2016","journal-title":"Oncol. Ther."},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib17","doi-asserted-by":"crossref","first-page":"8172","DOI":"10.1038\/s41467-024-52416-0","article-title":"Transvascular transport of nanocarriers for tumor delivery","volume":"15","author":"Li","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jddst.2025.107341_bib18","doi-asserted-by":"crossref","first-page":"400","DOI":"10.3389\/fcell.2020.00400","article-title":"Nanotechnology-based histone deacetylase inhibitors for cancer therapy","volume":"8","author":"Tu","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"issue":"5","key":"10.1016\/j.jddst.2025.107341_bib19","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1166\/jbn.2019.2764","article-title":"Peptide self-assembly nanoparticles loaded with panobinostat to activate latent human immunodeficiency virus","volume":"15","author":"Kuai","year":"2019","journal-title":"J. Biomed. Nanotechnol."},{"issue":"18","key":"10.1016\/j.jddst.2025.107341_bib20","doi-asserted-by":"crossref","first-page":"20960","DOI":"10.1021\/acsami.0c22587","article-title":"\u03b2-Cyclodextrin-poly (\u03b2-Amino ester) nanoparticles are a generalizable strategy for high loading and sustained release of HDAC inhibitors","volume":"13","author":"Chaudhuri","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"8","key":"10.1016\/j.jddst.2025.107341_bib21","first-page":"2256","article-title":"A recent review on","volume":"15","author":"Giri","year":"2023","journal-title":"Cancer Nanomedicine"},{"issue":"27","key":"10.1016\/j.jddst.2025.107341_bib22","doi-asserted-by":"crossref","first-page":"3218","DOI":"10.2174\/1381612826666200622133407","article-title":"Recent advances in lipid-based nanodrug delivery systems in cancer therapy","volume":"26","author":"Layek","year":"2020","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.jddst.2025.107341_bib23","article-title":"Preparation and evaluation of gemcitabin and cisplatin-entrapped Folate-PEGylated liposomes as targeting co-drug delivery system in cancer therapy","volume":"65","author":"Pakdaman Goli","year":"2021","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"10.1016\/j.jddst.2025.107341_bib24","article-title":"Fabrication and characterization of calcium carbonate nanoparticles for delivery of doxorubicin in breast cancer cells","volume":"109","author":"Mosaheb","year":"2025","journal-title":"J. Drug Deliv. Sci. Technol."},{"issue":"3","key":"10.1016\/j.jddst.2025.107341_bib25","first-page":"2872","article-title":"Targeted delivery of letrozole using a modified metal\u2013organic framework as a promising candidate in breast cancer therapy","volume":"14","author":"Ghaderpour","year":"2024"},{"issue":"10","key":"10.1016\/j.jddst.2025.107341_bib26","doi-asserted-by":"crossref","first-page":"4217","DOI":"10.1007\/s10570-017-1426-3","article-title":"Surfactant effects on the particle size, zeta potential, and stability of starch nanoparticles and their use in a pH-responsive manner","volume":"24","author":"Masoudipour","year":"2017","journal-title":"Cellulose"},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/03639045.2016.1254240","article-title":"Hydrophobic amino acids grafted onto chitosan: a novel amphiphilic chitosan nanocarrier for hydrophobic drugs","volume":"43","author":"Motiei","year":"2017","journal-title":"Drug Dev. Ind. Pharm."},{"key":"10.1016\/j.jddst.2025.107341_bib28","article-title":"Dual drug delivery of trapoxin A and methotrexate from biocompatible PLGA-PEG polymeric nanoparticles enhanced antitumor activity in breast cancer cell line","volume":"61","author":"Akbari","year":"2021","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"10.1016\/j.jddst.2025.107341_bib29","article-title":"Lapatinib loaded exosomes as a drug delivery system in breast cancer","volume":"75","author":"De\u011firmenci","year":"2022","journal-title":"J. Drug Deliv. Sci. Technol."},{"issue":"7","key":"10.1016\/j.jddst.2025.107341_bib30","doi-asserted-by":"crossref","first-page":"599","DOI":"10.2217\/nnm-2022-0328","article-title":"Dual-targeting exosomes for improved drug delivery in breast cancer","volume":"18","author":"Tran","year":"2023","journal-title":"Nanomedicine (London, England)"},{"key":"10.1016\/j.jddst.2025.107341_bib31","article-title":"Protein based nanostructures for drug delivery","volume":"2018","author":"Verma","year":"2018","journal-title":"J. Pharm. (Lahore)"},{"issue":"4","key":"10.1016\/j.jddst.2025.107341_bib32","first-page":"930","article-title":"Albumin-based nanoparticles: a promising strategy to overcome cancer drug resistance","volume":"3","author":"Hassanin","year":"2020","journal-title":"Cancer Drug Resist"},{"issue":"38","key":"10.1016\/j.jddst.2025.107341_bib33","doi-asserted-by":"crossref","first-page":"63311","DOI":"10.18632\/oncotarget.18800","article-title":"Bufalin-loaded bovine serum albumin nanoparticles demonstrated improved anti-tumor activity against hepatocellular carcinoma: preparation, characterization, pharmacokinetics and tissue distribution","volume":"8","author":"Zhang","year":"2017","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib34","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.colsurfb.2009.08.049","article-title":"Characterisation of the de-agglomeration effects of bovine serum albumin on nanoparticles in aqueous suspension","volume":"75","author":"Tantra","year":"2010","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"4","key":"10.1016\/j.jddst.2025.107341_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0250670","article-title":"A novel preparative method for nanoparticle albumin-bound paclitaxel with high drug loading and its evaluation both in vitro and in vivo","volume":"16","author":"Gao","year":"2021","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jddst.2025.107341_bib36","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.cell.2007.08.006","article-title":"Modeling tissue morphogenesis and cancer in 3D","volume":"130","author":"Yamada","year":"2007","journal-title":"Cell"},{"issue":"11","key":"10.1016\/j.jddst.2025.107341_bib37","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1080\/17425247.2016.1193149","article-title":"Albumin nanostructures as advanced drug delivery systems","volume":"13","author":"Karimi","year":"2016","journal-title":"Expet Opin. Drug Deliv."},{"key":"10.1016\/j.jddst.2025.107341_bib38","article-title":"Albumin-stabilized polydopamine nanoparticles for chemo-photothermal synergistic therapy of melanoma","volume":"87","author":"Li","year":"2023","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"10.1016\/j.jddst.2025.107341_bib39","doi-asserted-by":"crossref","first-page":"6945","DOI":"10.2147\/IJN.S467876","article-title":"Albumin nanoparticle-based drug delivery systems","volume":"19","author":"Qu","year":"2024","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.jddst.2025.107341_bib40","first-page":"669","article-title":"Preparation, characterization, and in vitro targeted delivery of folate-decorated paclitaxel-loaded bovine serum albumin nanoparticles","volume":"5","author":"Zhao","year":"2010","journal-title":"Int. J. Nanomed."},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib41","first-page":"6","article-title":"KinetDS: an open source software for dissolution test data analysis","volume":"19","author":"Mendyk","year":"2012"},{"issue":"12","key":"10.1016\/j.jddst.2025.107341_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics15122648","article-title":"Bovine serum albumin nanoparticles enhanced the intranasal bioavailability of silybin in rats","volume":"15","author":"Tartari","year":"2023","journal-title":"Pharmaceutics"},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib43","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1080\/10717544.2020.1797243","article-title":"Engineered bovine serum albumin-based nanoparticles with pH-sensitivity for doxorubicin delivery and controlled release","volume":"27","author":"Yang","year":"2020","journal-title":"Drug Deliv."},{"issue":"7","key":"10.1016\/j.jddst.2025.107341_bib44","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics11070297","article-title":"Potential albumin-based antioxidant nanoformulations for ocular protection against oxidative stress","volume":"11","author":"Kim","year":"2019","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.jddst.2025.107341_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.134651","article-title":"Bovine serum albumin as a nanocarrier for efficient encapsulation of hydrophobic garcinol-A strategy for modifying the in vitro drug release kinetics","volume":"278","author":"Ganguly","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib46","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-21568-8","article-title":"Preparation, physicochemical characterization, and bioactivity evaluation of berberine-entrapped albumin nanoparticles","volume":"12","author":"Younis","year":"2022","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.jddst.2025.107341_bib47","doi-asserted-by":"crossref","first-page":"3685","DOI":"10.1021\/acs.molpharmaceut.2c00479","article-title":"New development in understanding drug\u2013polymer interactions in pharmaceutical amorphous solid dispersions from solid-state nuclear magnetic resonance","volume":"19","author":"Pugliese","year":"2022","journal-title":"Mol. Pharm."},{"issue":"3","key":"10.1016\/j.jddst.2025.107341_bib48","doi-asserted-by":"crossref","first-page":"318","DOI":"10.3109\/10837450.2013.778874","article-title":"Polymeric microparticles-based formulation for the eradication of cutaneous candidiasis: development and characterization","volume":"19","author":"Kumar","year":"2014","journal-title":"Pharmaceut. Dev. Technol."},{"issue":"1\u20132","key":"10.1016\/j.jddst.2025.107341_bib49","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.ijpharm.2014.09.011","article-title":"Liprosomes loading paclitaxel for brain-targeting delivery by intravenous administration: in vitro characterization and in vivo evaluation","volume":"475","author":"Tang","year":"2014","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jddst.2025.107341_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfa.2020.125501","article-title":"Bovine serum albumin nanoparticles for the efficient delivery of berberine: preparation, characterization and in vitro biological studies","volume":"608","author":"Solanki","year":"2021","journal-title":"Colloids Surf. A Physicochem. Eng. Asp."},{"issue":"11","key":"10.1016\/j.jddst.2025.107341_bib51","doi-asserted-by":"crossref","first-page":"4394","DOI":"10.1039\/C9NJ05847H","article-title":"BSA nanoparticles as controlled release carriers for isophethalaldoxime palladacycle complex; synthesis, characterization, in vitro evaluation, cytotoxicity and release kinetics analysis","volume":"44","author":"Karami","year":"2020","journal-title":"New J. Chem."},{"issue":"12","key":"10.1016\/j.jddst.2025.107341_bib52","doi-asserted-by":"crossref","first-page":"6348","DOI":"10.1021\/acsomega.9b03716","article-title":"Comparative Analysis of Au and Au@SiO2 Nanoparticle\u2013Protein Interactions for Evaluation as Platforms in Theranostic Applications","volume":"5","author":"Swinton","year":"2020","journal-title":"ACS Omega"},{"issue":"1","key":"10.1016\/j.jddst.2025.107341_bib53","first-page":"13","article-title":"A synergistic pH-Responsive serum albumin-based drug delivery system loaded with doxorubicin and pentacyclic triterpene betulinic acid for potential treatment of NSCLC","volume":"12","author":"Torres-Martinez","year":"2023"},{"issue":"18","key":"10.1016\/j.jddst.2025.107341_bib54","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24183395","article-title":"Formation and stabilization of gold nanoparticles in bovine serum albumin solution","volume":"24","author":"Matei","year":"2019","journal-title":"Molecules"},{"issue":"3","key":"10.1016\/j.jddst.2025.107341_bib55","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/nrm1858","article-title":"Capturing complex 3D tissue physiology in vitro","volume":"7","author":"Griffith","year":"2006","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jddst.2025.107341_bib56","doi-asserted-by":"crossref","first-page":"161","DOI":"10.2147\/IJN.S187886","article-title":"Cellular effects of paclitaxel-loaded iron oxide nanoparticles on breast cancer using different 2D and 3D cell culture models","volume":"14","author":"Lugert","year":"2019","journal-title":"Int. J. Nanomed."}],"container-title":["Journal of Drug Delivery Science and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1773224725007440?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1773224725007440?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T17:26:23Z","timestamp":1760289983000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1773224725007440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":55,"alternative-id":["S1773224725007440"],"URL":"https:\/\/doi.org\/10.1016\/j.jddst.2025.107341","relation":{},"ISSN":["1773-2247"],"issn-type":[{"value":"1773-2247","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Panobinostat-loaded albumin nanoparticles for the treatment of pancreatic cancer","name":"articletitle","label":"Article Title"},{"value":"Journal of Drug Delivery Science and Technology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jddst.2025.107341","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107341"}}