{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T04:13:04Z","timestamp":1782274384867,"version":"3.54.5"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,12,24]],"date-time":"2013-12-24T00:00:00Z","timestamp":1387843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"name":"Research Grant Council, Hong Kong","award":["HKU765111M"],"award-info":[{"award-number":["HKU765111M"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.jdent.2013.12.007","type":"journal-article","created":{"date-parts":[[2013,12,25]],"date-time":"2013-12-25T06:15:33Z","timestamp":1387952133000},"page":"395-402","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":139,"title":["An ex vivo study of arrested primary teeth caries with silver diamine fluoride therapy"],"prefix":"10.1016","volume":"42","author":[{"given":"May L.","family":"Mei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward C.M.","family":"Lo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Q.L.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.H.","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdent.2013.12.007_bib0005","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1177\/0810767","article-title":"Effectiveness of silver diamine fluoride and sodium fluoride varnish in arresting dentin caries in Chinese pre-school children","volume":"81","author":"Chu","year":"2002","journal-title":"Journal of Dental Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0010","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1177\/154405910508400807","article-title":"Efficacy of silver diamine fluoride for caries reduction in primary teeth and first permanent molars of schoolchildren: 36-month clinical trial","volume":"84","author":"Llodra","year":"2005","journal-title":"Journal of Dental Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0015","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1177\/0022034510375825","article-title":"A randomized trial on root caries prevention in elders","volume":"89","author":"Tan","year":"2010","journal-title":"Journal of Dental Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0020","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1159\/000346620","article-title":"Silver diamine fluoride and education to prevent and arrest root caries among community-dwelling elders","volume":"47","author":"Zhang","year":"2013","journal-title":"Caries Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0025","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1177\/0022034508329406","article-title":"Silver diamine fluoride: a caries silver-fluoride bullet","volume":"88","author":"Rosenblatt","year":"2009","journal-title":"Journal of Dental Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0030","first-page":"315","article-title":"Promoting caries arrest in children with silver diamine fluoride: a review","volume":"6","author":"Chu","year":"2008","journal-title":"Oral Health and Preventive Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0035","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1754-4505.2012.00318.x","article-title":"Prevention of root caries: a literature review of primary and secondary preventive agents","volume":"33","author":"Gluzman","year":"2013","journal-title":"Special Care Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0040","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jdent.2012.03.009","article-title":"Silver compounds used in dentistry for caries management: a review","volume":"40","author":"Peng","year":"2012","journal-title":"Journal of Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0045","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1365-263X.2011.01149.x","article-title":"Effects of silver diamine fluoride on dentine carious lesions induced by Streptococcus mutans and Actinomyces naeslundii biofilms","volume":"22","author":"Chu","year":"2012","journal-title":"International Journal of Paediatric Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0050","doi-asserted-by":"crossref","first-page":"824","DOI":"10.4317\/medoral.18831","article-title":"Caries arresting effect of silver diamine fluoride on dentine carious lesion with S. mutans and L. acidophilus dual-species cariogenic biofilm","volume":"18","author":"Mei","year":"2013","journal-title":"Medicina Oral Patologia Oral y Cirugia Bucal"},{"key":"10.1016\/j.jdent.2013.12.007_bib0055","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1476-0711-12-4","article-title":"Antibacterial effects of silver diamine fluoride on multi-species cariogenic biofilm on caries","volume":"12","author":"Mei","year":"2013","journal-title":"Annals of Clinical Microbiology and Antimicrobials"},{"key":"10.1016\/j.jdent.2013.12.007_bib0060","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.dental.2012.04.011","article-title":"The inhibitory effects of silver diamine fluoride at different concentrations on matrix metalloproteinases","volume":"28","author":"Mei","year":"2012","journal-title":"Dental Materials"},{"key":"10.1016\/j.jdent.2013.12.007_bib0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2013.06.009","article-title":"The inhibitory effects of silver diamine fluoride on cysteine cathepsins","author":"Mei","year":"2013","journal-title":"Journal of Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0070","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1834-7819.2011.01641.x","article-title":"Effect of silver and fluoride ions on enamel demineralization: a quantitative study using micro-computed tomography","volume":"57","author":"Liu","year":"2012","journal-title":"Australian Dental Journal"},{"key":"10.1016\/j.jdent.2013.12.007_bib0075","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.jdent.2008.02.013","article-title":"Microhardness of dentine in primary teeth after topical fluoride applications","volume":"36","author":"Chu","year":"2008","journal-title":"Journal of Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0080","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.jdent.2011.06.008","article-title":"Reaction of silver diamine [corrected] fluoride with hydroxyapatite and protein","volume":"39","author":"Lou","year":"2011","journal-title":"Journal of Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0085","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/ipd.12005","article-title":"Fluoride and silver concentrations of silver diammine fluoride solutions for dental use","volume":"23","author":"Mei","year":"2013","journal-title":"International Journal of Paediatric Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0090","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1186\/1471-2458-12-767","article-title":"Oral health status and behaviours of preschool children in Hong Kong","volume":"12","author":"Chu","year":"2012","journal-title":"BioMed Central Public Health"},{"key":"10.1016\/j.jdent.2013.12.007_bib0095","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.surge.2012.12.010","article-title":"Oral health and dental care in Hong Kong","volume":"11","author":"Chu","year":"2013","journal-title":"Surgeon"},{"key":"10.1016\/j.jdent.2013.12.007_bib0100","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1177\/00220345970760120701","article-title":"Arrest of root surface caries in situ","volume":"76","author":"Nyvad","year":"1997","journal-title":"Journal of Dental Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0105","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1159\/000260479","article-title":"Ultrastructure of the human odontoblast process and its mineralisation during dental caries","volume":"14","author":"Frank","year":"1980","journal-title":"Caries Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0110","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000016444","article-title":"Inhibition of dentin demineralization by fluoride in vitro","volume":"32","author":"ten Cate","year":"1998","journal-title":"Caries Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0115","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.jdent.2013.06.009","article-title":"Inhibitory effect of silver diamine fluoride on dentine demineralisation and collagen degradation","volume":"41","author":"Mei","year":"2013","journal-title":"Journal of Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0120","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1159\/000260536","article-title":"The effect of fluoride in saliva on remineralization of dental enamel in humans","volume":"15","author":"Lambrou","year":"1981","journal-title":"Caries Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0125","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.jdent.2013.06.008","article-title":"Biomimetic mineralisation of phosphorylated dentine by CPP-ACP","volume":"41","author":"Cao","year":"2013","journal-title":"Journal of Dentistry"},{"key":"10.1016\/j.jdent.2013.12.007_bib0130","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1177\/154405910308201204","article-title":"The importance of intrafibrillar mineralization of collagen on the mechanical properties of dentin","volume":"82","author":"Kinney","year":"2003","journal-title":"Journal of Dental Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0135","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1177\/0022034512455801","article-title":"Impact of protease inhibitors on dentin matrix degradation by collagenase","volume":"91","author":"Kato","year":"2012","journal-title":"Journal of Dental Research"},{"key":"10.1016\/j.jdent.2013.12.007_bib0140","first-page":"1465","article-title":"Size-dependent antibacterial activities of silver nanoparticles against oral anaerobic pathogenic bacteria","volume":"24","author":"Lu","year":"2013","journal-title":"Journal of Materials Science"},{"key":"10.1016\/j.jdent.2013.12.007_bib0145","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.biotechadv.2008.09.002","article-title":"Silver nanoparticles as a new generation of antimicrobials","volume":"27","author":"Rai","year":"2009","journal-title":"Biotechnology Advances"}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571213003424?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571213003424?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T00:21:24Z","timestamp":1759537284000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300571213003424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S0300571213003424"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2013.12.007","relation":{},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An ex vivo study of arrested primary teeth caries with silver diamine fluoride therapy","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2013.12.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}