{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:43:35Z","timestamp":1793292215862,"version":"4.5.0"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.jdent.2021.103641","type":"journal-article","created":{"date-parts":[[2021,3,20]],"date-time":"2021-03-20T21:08:54Z","timestamp":1616274534000},"page":"103641","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Bonding to dentin using an experimental zirconium oxynitrate etchant"],"prefix":"10.1016","volume":"108","author":[{"given":"Edoardo","family":"Mancuso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allegra","family":"Comba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Mazzitelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatjana","family":"Maravic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uros","family":"Josic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Del Bianco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franklin R.","family":"Tay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Breschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Mazzoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdent.2021.103641_bib0005","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.dental.2010.10.023","article-title":"State of the art of self-etch adhesives","volume":"27","author":"Van Meerbeek","year":"2011","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2021.103641_bib0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.dental.2010.10.016","article-title":"State of the art etch-and-rinse adhesives","volume":"27","author":"Pashley","year":"2011","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2021.103641_bib0015","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.dental.2017.11.005","article-title":"Dentin bonding systems: from dentin collagen structure to bond preservation and clinical applications","volume":"34","author":"Breschi","year":"2018","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2021.103641_bib0020","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.dental.2007.02.009","article-title":"Dental adhesion review: aging and stability of the bonded interface","volume":"24","author":"Breschi","year":"2008","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2021.103641_bib0025","first-page":"28","article-title":"The effect of variation in etching times on dentin bonding","volume":"52","author":"Abu-Hanna","year":"2004","journal-title":"Gen. Dent."},{"key":"10.1016\/j.jdent.2021.103641_bib0030","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0300-5712(02)00004-0","article-title":"Over-etching effects on micro-tensile bond strength and failure patterns for two dentin bonding systems","volume":"30","author":"Hashimoto","year":"2002","journal-title":"J. Dent."},{"key":"10.1016\/j.jdent.2021.103641_bib0035","doi-asserted-by":"crossref","first-page":"4470","DOI":"10.1016\/j.biomaterials.2006.01.040","article-title":"Reactivation of inactivated endogenous proteolytic activities in phosphoric acid-etched dentine by etch-and-rinse adhesives","volume":"27","author":"Mazzoni","year":"2006","journal-title":"Biomaterials"},{"key":"10.1016\/j.jdent.2021.103641_bib0040","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1600-0722.2006.00342.x","article-title":"Activation of gelatinolytic\/collagenolytic activity in dentin by self-etching adhesives","volume":"114","author":"Nishitani","year":"2006","journal-title":"Eur. J. Oral Sci."},{"key":"10.1016\/j.jdent.2021.103641_bib0045","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1177\/154405910408300306","article-title":"Collagen degradation by host-derived enzymes during aging","volume":"83","author":"Pashley","year":"2004","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2021.103641_bib0050","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1177\/0022034512446339","article-title":"Effects of MMP inhibitors incorporated within dental adhesives","volume":"91","author":"Almahdy","year":"2012","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2021.103641_bib0055","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/j.dental.2019.07.022","article-title":"Bonding to enamel using alternative Enamel Conditioner\/etchants","volume":"35","author":"Yao","year":"2019","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2021.103641_bib0060","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.dental.2011.04.011","article-title":"Hydration characteristics of zirconium oxide replaced Portland cement for use as a root-end filling material","volume":"27","author":"Camilleri","year":"2011","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2021.103641_bib0065","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1177\/154405910208100708","article-title":"Two modes of nanoleakage expression in single-step adhesives","volume":"81","author":"Tay","year":"2002","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2021.103641_bib0070","article-title":"Adhesion of a two-step etch-and-rinse adhesive on collagen-depleted dentin","volume":"10","author":"Saboia","year":"2008","journal-title":"J. Adhes. Dent."},{"key":"10.1016\/j.jdent.2021.103641_bib0075","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1177\/0022034512467034","article-title":"Effects of etch-and-rinse and self-etch adhesives on dentin MMP-2 and MMP-9","volume":"92","author":"Mazzoni","year":"2013","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2021.103641_bib0080","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.jdent.2019.01.007","article-title":"Carbodiimide inactivation of matrix metalloproteinases in radicular dentine","volume":"82","author":"Comba","year":"2019","journal-title":"J. Dent."},{"key":"10.1016\/j.jdent.2021.103641_bib0085","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1070\/RC1962v031n11ABEH001326","article-title":"The chemistry of aqueous solutions of zirconium salts (does the zirconyl ion exist?)","volume":"31","author":"Solovkin","year":"1962","journal-title":"Russ. Chem. Rev."},{"key":"10.1016\/j.jdent.2021.103641_bib0090","first-page":"103","article-title":"Influence of laboratory degradation methods and bonding application parameters on microTBS of self-etch adhesives to dentin","volume":"24","author":"Erhardt","year":"2011","journal-title":"Am. J. Dent."},{"key":"10.1016\/j.jdent.2021.103641_bib0095","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1161\/01.RES.0000070112.80711.3D","article-title":"Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry","volume":"92","author":"Visse","year":"2003","journal-title":"Circ. Res."},{"key":"10.1016\/j.jdent.2021.103641_bib0100","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jdent.2008.12.002","article-title":"EDTA or H3PO4\/NaOCl dentine treatments may increase hybrid layers\u2019 resistance to degradation: a microtensile bond strength and confocal-micropermeability study","volume":"37","author":"Sauro","year":"2009","journal-title":"J. Dent."},{"key":"10.1016\/j.jdent.2021.103641_bib0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.dental.2012.04.025","article-title":"Apatite crystal protection against acid-attack beneath resin-dentin interface with four adhesives: TEM and crystallography evidence","volume":"28","author":"Nurrohman","year":"2012","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2021.103641_bib0110","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1177\/0022034512437375","article-title":"Self-assembled nano-layering at the adhesive interface","volume":"91","author":"Yoshida","year":"2012","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2021.103641_bib0115","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.jdent.2012.02.012","article-title":"Bonding effectiveness of a new \u201cmulti-mode\u201d adhesive to enamel and dentine","volume":"40","author":"Hanabusa","year":"2012","journal-title":"J. Dent."},{"key":"10.1016\/j.jdent.2021.103641_bib0120","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1177\/154405910808700712","article-title":"Analysis of the degradation of a model dental composite","volume":"87","author":"Koin","year":"2008","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2021.103641_bib0125","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1177\/0022034510363380","article-title":"Implication of ethanol wet-bonding in hybrid layer remineralization","volume":"89","author":"Kim","year":"2010","journal-title":"J. Dent. Res."}],"updated-by":[{"DOI":"10.1016\/j.jdent.2021.103691","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000}}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571221000622?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571221000622?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T13:47:09Z","timestamp":1674568029000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300571221000622"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":25,"alternative-id":["S0300571221000622"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2021.103641","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.jdent.2021.103691","asserted-by":"object"}]},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bonding to dentin using an experimental zirconium oxynitrate etchant","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2021.103641","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103641"}}