{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T01:26:55Z","timestamp":1778894815934,"version":"3.51.4"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100019018","name":"Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005150","name":"Chinese Academy of Medical Sciences &amp; Peking Union Medical College","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005150","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.jdent.2024.105269","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T16:41:04Z","timestamp":1722444064000},"page":"105269","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["An explainable predictive model of direct pulp capping in carious mature permanent teeth"],"prefix":"10.1016","volume":"149","author":[{"given":"Yunzi","family":"Long","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siyi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiao","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanmei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"17","key":"10.1016\/j.jdent.2024.105269_bib0001","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1001\/jama.1992.03490170092032","article-title":"Evidence-based medicine. a new approach to teaching the practice of medicine","volume":"268","year":"1992","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.jdent.2024.105269_bib0002","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s12910-015-0063-3","article-title":"The importance of values in evidence-based medicine","volume":"16","author":"Kelly","year":"2015","journal-title":"BMC Med. Ethics"},{"issue":"1","key":"10.1016\/j.jdent.2024.105269_bib0003","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1186\/s12967-020-02620-5","article-title":"Predicting 30-days mortality for MIMIC-III patients with sepsis-3: a machine learning approach using XGBoost","volume":"18","author":"Hou","year":"2020","journal-title":"J. Transl. Med."},{"issue":"2","key":"10.1016\/j.jdent.2024.105269_bib0004","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jointm.2021.09.002","article-title":"Machine learning using the extreme gradient boosting (XGBoost) algorithm predicts 5-day delta of SOFA score at ICU admission in COVID-19 patients","volume":"1","author":"Montomoli","year":"2021","journal-title":"J. Intensive Med."},{"issue":"1","key":"10.1016\/j.jdent.2024.105269_bib0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/dj11010001","article-title":"Machine learning predictive model as clinical decision support system in orthodontic treatment planning","volume":"11","author":"Prasad","year":"2022","journal-title":"Dent. J. (Basel)"},{"issue":"3","key":"10.1016\/j.jdent.2024.105269_bib0006","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1080\/10255842.2023.2187671","article-title":"Prediction of wear of dental composite materials using machine learning algorithms","volume":"27","author":"Suryawanshi","year":"2024","journal-title":"Comput. Methods Biomech. Biomed. Engin."},{"key":"10.1016\/j.jdent.2024.105269_bib0007","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/7307675","article-title":"Prediction of dental implants using machine learning algorithms","volume":"2022","author":"Alharbi","year":"2022","journal-title":"J. Healthc Eng."},{"issue":"6","key":"10.1016\/j.jdent.2024.105269_bib0008","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.tig.2020.03.005","article-title":"Opening the black box: interpretable machine learning for geneticists","volume":"36","author":"Azodi","year":"2020","journal-title":"Trends Genet."},{"key":"10.1016\/j.jdent.2024.105269_bib0009","series-title":"Proceedings of the 31st International Conference on Neural Information Processing Systems (NIPS'17)","first-page":"4768","article-title":"A unified approach to interpreting model predictions","author":"Lundberg","year":"2017"},{"key":"10.1016\/j.jdent.2024.105269_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.aap.2021.106261","article-title":"Quantifying and comparing the effects of key risk factors on various types of roadway segment crashes with LightGBM and SHAP","volume":"159","author":"Wen","year":"2021","journal-title":"Accid. Anal. Prev."},{"key":"10.1016\/j.jdent.2024.105269_bib0011","article-title":"Explainable deep learning predictions for illness risk of mental disorders in Nanjing","volume":"202","author":"Wang","year":"2021","journal-title":"China. Environ. Res."},{"issue":"1","key":"10.1016\/j.jdent.2024.105269_bib0012","first-page":"46","article-title":"Vital pulp therapy an insight over the available literature and future expectations","volume":"5","author":"Hanna","year":"2020","journal-title":"Eur. Endod. J."},{"issue":"9","key":"10.1016\/j.jdent.2024.105269_bib0013","doi-asserted-by":"crossref","first-page":"5287","DOI":"10.1007\/s00784-023-05148-2","article-title":"Multivariate prognostic analysis of direct pulp capping using a bioceramic material in mature permanent teeth with carious pulp exposure: a retrospective cohort study","volume":"27","author":"Chen","year":"2023","journal-title":"Clin. Oral Investig."},{"issue":"5","key":"10.1016\/j.jdent.2024.105269_bib0014","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1007\/s00784-017-2296-7","article-title":"Factors affecting the outcomes of direct pulp capping using Biodentine","volume":"22","author":"Lipski","year":"2018","journal-title":"Clin. Oral Investig."},{"issue":"10","key":"10.1016\/j.jdent.2024.105269_bib0015","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1016\/j.joen.2017.06.017","article-title":"Treatment outcome following direct pulp capping using bioceramic materials in mature permanent teeth with carious exposure: a pilot retrospective study","volume":"43","author":"Linu","year":"2017","journal-title":"J. Endod."},{"issue":"12","key":"10.1016\/j.jdent.2024.105269_bib0016","first-page":"945","article-title":"Clinical efficacy observation of direct pulp capping using iRoot BP Plus therapy in mature permanent teeth with carious pulp exposure","volume":"55","author":"Liu","year":"2020","journal-title":"Zhonghua Kou Qiang Yi Xue Za Zhi"},{"issue":"9","key":"10.1016\/j.jdent.2024.105269_bib0017","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.1007\/s00784-018-2767-5","article-title":"Clinical evaluation of direct pulp capping using a calcium silicate cement-treatment outcomes over an average period of 2.3 years","volume":"23","author":"Harms","year":"2019","journal-title":"Clin. Oral Investig."},{"issue":"10","key":"10.1016\/j.jdent.2024.105269_bib0018","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1111\/iej.12719","article-title":"Capping carious exposures in adults: a randomized controlled trial investigating mineral trioxide aggregate versus calcium hydroxide","volume":"50","author":"Kundzina","year":"2017","journal-title":"Int. Endod. J."},{"issue":"7","key":"10.1016\/j.jdent.2024.105269_bib0019","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.joen.2019.02.025","article-title":"Success of direct pulp capping using mineral trioxide aggregate and calcium hydroxide in mature permanent molars with pulps exposed during carious tissue removal: 1-year follow-up","volume":"45","author":"Suhag","year":"2019","journal-title":"J. Endod."},{"key":"10.1016\/j.jdent.2024.105269_bib0020","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jdent.2019.05.022","article-title":"Vital pulp therapy: histopathology and histobacteriology-based guidelines to treat teeth with deep caries and pulp exposure","volume":"86","author":"Ricucci","year":"2019","journal-title":"J. Dent."},{"issue":"1","key":"10.1016\/j.jdent.2024.105269_bib0021","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.joen.2022.11.005","article-title":"Outcome of direct pulp capping using calcium hydroxide: a long-term retrospective study","volume":"49","author":"Ricucci","year":"2023","journal-title":"J. Endod."},{"issue":"11","key":"10.1016\/j.jdent.2024.105269_bib0022","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/j.joen.2018.08.004","article-title":"Outcomes of vital pulp therapy using mineral trioxide aggregate or Biodentine: a prospective randomized clinical trial","volume":"44","author":"Awawdeh","year":"2018","journal-title":"J. Endod."},{"issue":"8","key":"10.1016\/j.jdent.2024.105269_bib0023","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.joen.2015.03.015","article-title":"A randomized controlled study of the use of ProRoot mineral trioxide aggregate and Endocem as direct pulp capping materials: 3-month versus 1-year outcomes","volume":"41","author":"Jang","year":"2015","journal-title":"J. Endod."},{"issue":"2","key":"10.1016\/j.jdent.2024.105269_bib0024","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.jds.2020.08.016","article-title":"Efficacy of different calcium silicate materials as pulp-capping agents: randomized clinical trial","volume":"16","author":"Peskersoy","year":"2021","journal-title":"J. Dent. Sci."},{"issue":"9","key":"10.1016\/j.jdent.2024.105269_bib0025","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1016\/j.joen.2021.07.015","article-title":"AAE position statement on vital pulp therapy","volume":"47","year":"2021","journal-title":"J. Endod."},{"issue":"6","key":"10.1016\/j.jdent.2024.105269_bib0026","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.joen.2023.04.005","article-title":"Factors affecting the decision-making of direct pulp capping procedures among dental practitioners: a multinational survey from 16 countries with meta-analysis","volume":"49","author":"Hatipo\u011flu","year":"2023","journal-title":"J. Endod."},{"key":"10.1016\/j.jdent.2024.105269_bib0027","series-title":"Machine Learning for Data Science Handbook","first-page":"143","article-title":"Soft decision trees","author":"Fivel","year":"2023"},{"issue":"4","key":"10.1016\/j.jdent.2024.105269_bib0028","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1162\/089976698300017575","article-title":"Properties of support vector machines","volume":"10","author":"Pontil","year":"1998","journal-title":"Neural Comput."},{"issue":"4","key":"10.1016\/j.jdent.2024.105269_bib0029","first-page":"190","article-title":"A review of the logistic regression model with emphasis on medical research","volume":"7","author":"Boateng","year":"2019","journal-title":"J. Data. Anal & Inf. Process"},{"key":"10.1016\/j.jdent.2024.105269_bib0030","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1010933404324","article-title":"Random forests","volume":"45","author":"Breiman","year":"2001","journal-title":"Mach Learn"},{"key":"10.1016\/j.jdent.2024.105269_bib0031","series-title":"International Conference on Intelligent Computing and Control Systems (ICCS)","first-page":"1255","article-title":"A brief review of Nearest Neighbor Algorithm for learning and classification","author":"Taunk","year":"2019"},{"key":"10.1016\/j.jdent.2024.105269_bib0032","series-title":"Proceedings of the 22nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining (KDD '16)","first-page":"785","article-title":"XGBoost: a Scalable Tree Boosting System","author":"Chen","year":"2016"},{"issue":"1","key":"10.1016\/j.jdent.2024.105269_bib0033","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.cell.2020.03.022","article-title":"How machine learning will transform biomedicine","volume":"181","author":"Goecks","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.jdent.2024.105269_bib0034","doi-asserted-by":"crossref","DOI":"10.1177\/11795468221133611","article-title":"XGBoost, a novel explainable AI technique, in the prediction of myocardial infarction: a UK biobank cohort study","volume":"16","author":"Moore","year":"2022","journal-title":"Clin. Med. Insights Cardiol."},{"issue":"5","key":"10.1016\/j.jdent.2024.105269_bib0035","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s00784-009-0326-9","article-title":"Long-term evaluation of direct pulp capping: treatment outcomes over an average period of 6.1 years","volume":"14","author":"Dammaschke","year":"2010","journal-title":"Clin. Oral Investig."},{"issue":"7","key":"10.1016\/j.jdent.2024.105269_bib0036","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/iej.13080","article-title":"European Society of Endodontology position statement: management of deep caries and the exposed pulp","volume":"52","author":"Duncan","year":"2019","journal-title":"Int. Endod. J."},{"issue":"12","key":"10.1016\/j.jdent.2024.105269_bib0037","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1177\/0022034512460833","article-title":"Effect of a calcium-silicate-based restorative cement on pulp repair","volume":"91","author":"Tran","year":"2012","journal-title":"J. Dent. Res."},{"issue":"9","key":"10.1016\/j.jdent.2024.105269_bib0038","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/j.joen.2015.04.012","article-title":"Direct pulp capping with calcium hydroxide or mineral trioxide aggregate: a meta-analysis","volume":"41","author":"Li","year":"2015","journal-title":"Endod"},{"issue":"4","key":"10.1016\/j.jdent.2024.105269_bib0039","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.jebdp.2018.02.002","article-title":"Direct pulp capping: what is the most effective therapy? systematic review and meta-analysis","volume":"18","author":"Paula","year":"2018","journal-title":"J. Evid. Based Dent. Pract."},{"issue":"4","key":"10.1016\/j.jdent.2024.105269_bib0040","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/iej.13449","article-title":"Efficacy of direct pulp capping for management of cariously exposed pulps in permanent teeth: a systematic review and meta-analysis","volume":"54","author":"Cushley","year":"2021","journal-title":"Int. Endod. J."},{"issue":"2","key":"10.1016\/j.jdent.2024.105269_bib0041","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s10856-012-4794-0","article-title":"In vitro studies of calcium phosphate silicate bone cements","volume":"24","author":"Zhou","year":"2013","journal-title":"J. Mater. Sci. Mater. Med."},{"issue":"5","key":"10.1016\/j.jdent.2024.105269_bib0042","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.joen.2014.12.009","article-title":"Evaluation of a bioceramic as a pulp capping agent in vitro and in vivo","volume":"41","author":"Liu","year":"2015","journal-title":"J. Endod."},{"issue":"2","key":"10.1016\/j.jdent.2024.105269_bib0043","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/iej.12439","article-title":"Comparison of in vivo dental pulp responses to capping with iRoot BP Plus and mineral trioxide aggregate","volume":"49","author":"Shi","year":"2016","journal-title":"Int. Endod. J."},{"issue":"12","key":"10.1016\/j.jdent.2024.105269_bib0044","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1111\/iej.13627","article-title":"Outcome measures to assess the effectiveness of endodontic treatment for pulpitis and apical periodontitis for use in the development of European Society of Endodontology S3-level clinical practice guidelines: a consensus-based development","volume":"54","author":"Duncan","year":"2021","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.jdent.2024.105269_bib0045","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s00784-016-1798-z","article-title":"Prognostic factors in direct pulp capping with mineral trioxide aggregate or calcium hydroxide: 2- to 6-year follow-up","volume":"21","author":"\u00c7al\u0131\u015fkan","year":"2017","journal-title":"Clin. Oral Investig."},{"issue":"9S","key":"10.1016\/j.jdent.2024.105269_bib0046","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/j.joen.2020.06.025","article-title":"Conservative management of mature permanent teeth with carious pulp exposure","volume":"46","author":"Taha","year":"2020","journal-title":"J. Endod."}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030057122400438X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030057122400438X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T19:09:25Z","timestamp":1726168165000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030057122400438X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":46,"alternative-id":["S030057122400438X"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2024.105269","relation":{},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An explainable predictive model of direct pulp capping in carious mature permanent teeth","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2024.105269","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105269"}}