{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T20:38:55Z","timestamp":1791664735411,"version":"4.3.4"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.jdent.2024.105313","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T15:50:55Z","timestamp":1724341855000},"page":"105313","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Comparison of the anti-plaque and anti-gingivitis efficacy of Chlorhexidine and Malva mouthwashes: Randomized crossover clinical trial"],"prefix":"10.1016","volume":"150","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4503-2643","authenticated-orcid":false,"given":"Giovanna Sacco","family":"Zuttion","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1221-6853","authenticated-orcid":false,"given":"Humberto Alexander Baca","family":"Ju\u00e1rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betina Dutra","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele Prado","family":"Assump\u00e7\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c2ndrea Pires","family":"Daneris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iuri H\u00f6rnke","family":"Tuchtenhagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u00edsa","family":"Casarin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3945-1752","authenticated-orcid":false,"given":"Francisco Wilker Mustafa Gomes","family":"Muniz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl 1","key":"10.1016\/j.jdent.2024.105313_bib0001","first-page":"S74","article-title":"Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"89","author":"Chapple","year":"2018","journal-title":"J. Periodontol."},{"key":"10.1016\/j.jdent.2024.105313_bib0002","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1902\/jop.1983.54.9.522","article-title":"Experimental gingivitis in humans. a clinical and histologic investigation","volume":"54","author":"Seymour","year":"1983","journal-title":"J. Periodontol."},{"issue":"Suppl 16","key":"10.1016\/j.jdent.2024.105313_bib0003","first-page":"S71","article-title":"Primary prevention of periodontitis: managing gingivitis","volume":"42","author":"Chapple","year":"2015","journal-title":"J. Clin. Periodontol."},{"issue":"Suppl","key":"10.1016\/j.jdent.2024.105313_bib0004","doi-asserted-by":"crossref","first-page":"16S","DOI":"10.14219\/jada.archive.2006.0408","article-title":"The rationale for the daily use of an antimicrobial mouthrinse","volume":"137","author":"Barnett","year":"2006","journal-title":"J. Am. Dent. Assoc."},{"key":"10.1016\/j.jdent.2024.105313_bib0005","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/jcpe.13127","article-title":"Efficacy of adjunctive antiplaque chemical agents in managing gingivitis: a systematic review and network meta-analyses","volume":"46","author":"Figuero","year":"2019","journal-title":"J. Clin. Periodontol."},{"key":"10.1016\/j.jdent.2024.105313_bib0006","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/odi.13254","article-title":"Effect of herbal mouthrinses on dental plaque formation and gingival inflammation: a systematic review","volume":"27","author":"Santi","year":"2021","journal-title":"Oral Dis."},{"key":"10.1016\/j.jdent.2024.105313_bib0007","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s00210-022-02329-w","article-title":"The phytochemical profiling, pharmacological activities, and safety of malva sylvestris: a review","volume":"396","author":"Batiha","year":"2023","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.jdent.2024.105313_bib0008","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0140331","article-title":"Malva sylvestris Inhibits Inflammatory Response in Oral Human Cells, An In Vitro Infection Model","volume":"10","author":"Benso","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jdent.2024.105313_bib0009","article-title":"A Review on Health Benefits of","volume":"2021","author":"Mousavi","year":"2021","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.jdent.2024.105313_bib0010","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.jep.2009.10.027","article-title":"Ethnobotanical and phytomedicinal knowledge in a long-history protected area, the Abruzzo, Lazio and Molise National Park (Italian Apennines)","volume":"127","author":"Idolo","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jdent.2024.105313_bib0011","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.2042-7158.2011.01383.x","article-title":"Ethnobotanical and scientific aspects of Malva sylvestris L.: a millennial herbal medicine","volume":"64","author":"Gasparetto","year":"2012","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.jdent.2024.105313_bib0012","doi-asserted-by":"crossref","first-page":"l4378","DOI":"10.1136\/bmj.l4378","article-title":"CONSORT 2010 statement: extension to randomised crossover trials","volume":"366","author":"Dwan","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.jdent.2024.105313_bib0013","doi-asserted-by":"crossref","first-page":"e062","DOI":"10.1590\/1807-3107bor-2019.vol33.0062","article-title":"Anti-biofilm and anti-inflammatory effect of a herbal nanoparticle mouthwash: a randomized crossover trial","volume":"33","author":"Casarin","year":"2019","journal-title":"Braz. Oral Res."},{"key":"10.1016\/j.jdent.2024.105313_bib0014","doi-asserted-by":"crossref","first-page":"466","DOI":"10.4103\/0976-237X.142813","article-title":"Comparative antiplaque and antigingivitis effectiveness of tea tree oil mouthwash and a cetylpyridinium chloride mouthwash: a randomized controlled crossover study","volume":"5","author":"Rahman","year":"2014","journal-title":"Contemp. Clin. Dent."},{"key":"10.1016\/j.jdent.2024.105313_bib0015","first-page":"3","article-title":"A modified gingival index for use in clinical trials","volume":"8","author":"Lobene","year":"1986","journal-title":"Clin. Prev. Dent."},{"key":"10.1016\/j.jdent.2024.105313_bib0016","first-page":"41","article-title":"Reduced plaque formation by the chloromethyl analogue of victamine C","volume":"41","author":"Turesky","year":"1970","journal-title":"J. Periodontol."},{"key":"10.1016\/j.jdent.2024.105313_bib0017","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.1601-5037.2010.00487.x","article-title":"The effect of 1% chlorhexidine gel and 0.12% dentifrice gel on plaque accumulation: a 3-day non-brushing model","volume":"8","author":"Slot","year":"2010","journal-title":"Int. J. Dent. Hyg."},{"key":"10.1016\/j.jdent.2024.105313_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2020.103415","article-title":"Antibiofilm and anti-caries effects of an experimental mouth rinse containing Matricaria chamomilla L. extract under microcosm biofilm on enamel","volume":"99","author":"Braga","year":"2020","journal-title":"J. Dent."},{"key":"10.1016\/j.jdent.2024.105313_bib0019","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.hermed.2016.01.001","article-title":"Clinical efficacy of an herbal mouth wash composed of Salix alba, Malva sylvestrais and Althaea officinalis in chronic periodontitis patients","volume":"6","author":"Radvar","year":"2016","journal-title":"J. Herbal Med."},{"key":"10.1016\/j.jdent.2024.105313_bib0020","first-page":"96","article-title":"Antioxidant properties and some phytochemical components of the edible medicinal Malva sylvestris L","volume":"7","author":"Petkova","year":"2019","journal-title":"J. Med. Plants"},{"key":"10.1016\/j.jdent.2024.105313_bib0021","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.joen.2011.02.007","article-title":"Antimicrobial efficacy of chlorhexidine against bacteria in biofilms at different stages of development","volume":"37","author":"Shen","year":"2011","journal-title":"J. Endod."},{"key":"10.1016\/j.jdent.2024.105313_bib0022","unstructured":"U.S. Food and Drug Administration. Center for drug evaluation and research, gingivitis: development and evaluation of drugs for treatment or prevention, U.S. food and drug administration. (2005)."},{"key":"10.1016\/j.jdent.2024.105313_bib0023","first-page":"ii6","article-title":"Statistical significance versus clinical relevance","volume":"32","author":"van Rijn","year":"2017","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.jdent.2024.105313_bib0024","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1590\/S1678-77572010000500015","article-title":"Staining and calculus formation after 0.12% chlorhexidine rinses in plaque-free and plaque covered surfaces: a randomized trial","volume":"18","author":"Zanatta","year":"2010","journal-title":"J. Appl. Oral Sci."},{"key":"10.1016\/j.jdent.2024.105313_bib0025","first-page":"574","article-title":"Bioactivity of malva sylvestris L., a medicinal plant from iran","volume":"14","author":"Razavi","year":"2011","journal-title":"Iran J. Basic Med. Sci."},{"key":"10.1016\/j.jdent.2024.105313_bib0026","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13020-018-0177-x","article-title":"Techniques for extraction and isolation of natural products: a comprehensive review","volume":"13","author":"Zhang","year":"2018","journal-title":"Chin. Med."},{"key":"10.1016\/j.jdent.2024.105313_bib0027","first-page":"59","article-title":"Medicinal plants, human health and biodiversity: a broad review","volume":"147","author":"Sen","year":"2015","journal-title":"Adv. Biochem. Eng. Biotechnol."},{"key":"10.1016\/j.jdent.2024.105313_bib0028","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.fct.2013.04.042","article-title":"Pre-clinical anti-inflammatory aspects of a cuisine and medicinal millennial herb: malva sylvestris L","volume":"58","author":"Prudente","year":"2013","journal-title":"Food. Chem. Toxicol."}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571224004822?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571224004822?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T21:00:26Z","timestamp":1729803626000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300571224004822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":28,"alternative-id":["S0300571224004822"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2024.105313","relation":{},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of the anti-plaque and anti-gingivitis efficacy of Chlorhexidine and Malva mouthwashes: Randomized crossover clinical trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2024.105313","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105313"}}