{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T12:25:53Z","timestamp":1793449553950,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002920","name":"University Grants Committee Research Grants Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.jdent.2024.105320","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T06:34:10Z","timestamp":1724913250000},"page":"105320","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Developing a novel antibacterial copper tetraamine fluoride"],"prefix":"10.1016","volume":"150","author":[{"given":"Veena Wenqing","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris Xiaoxue","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3471-180X","authenticated-orcid":false,"given":"John Yun","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5310-5039","authenticated-orcid":false,"given":"Ollie Yiru","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6041-1907","authenticated-orcid":false,"given":"Mohammed Zahedul Islam","family":"Nizami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8167-0430","authenticated-orcid":false,"given":"Chun Hung","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jdent.2024.105320_bib0001","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1875-595X.2008.tb00185.x","article-title":"World Health Organization global policy for improvement of oral health\u2013World Health Assembly 2007","volume":"58","author":"Petersen","year":"2008","journal-title":"Int Dent J"},{"key":"10.1016\/j.jdent.2024.105320_bib0002","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.2147\/IJN.S253833","article-title":"Use of silver nanomaterials for caries prevention: a concise review","volume":"15","author":"Yin","year":"2020","journal-title":"Int J Nanomedicine"},{"issue":"9555","key":"10.1016\/j.jdent.2024.105320_bib0003","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0140-6736(07)60031-2","article-title":"Dental caries","volume":"369","author":"Selwitz","year":"2007","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.jdent.2024.105320_bib0004","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1080\/10717544.2022.2037788","article-title":"Effect of pH-sensitive nanoparticles on inhibiting oral biofilms","volume":"29","author":"Peng","year":"2022","journal-title":"Drug Deliv"},{"key":"10.1016\/j.jdent.2024.105320_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.archoralbio.2020.105022","article-title":"Antimicrobial peptides for the prevention and treatment of dental caries: a concise review","volume":"122","author":"Niu","year":"2021","journal-title":"Arch Oral Biol"},{"issue":"1","key":"10.1016\/j.jdent.2024.105320_bib0006","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3390\/jfb15010010","article-title":"Copper materials for caries management: a scoping review","volume":"15","author":"Xu","year":"2024","journal-title":"J Funct Biomater"},{"issue":"5","key":"10.1016\/j.jdent.2024.105320_bib0007","doi-asserted-by":"crossref","DOI":"10.3390\/jfb15050120","article-title":"Design of multi-functional bio-safe dental resin composites with mineralization and anti-biofilm properties","volume":"15","author":"Yun","year":"2024","journal-title":"J Funct Biomater"},{"issue":"10","key":"10.1016\/j.jdent.2024.105320_bib0008","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph14101204","article-title":"Managing Early Childhood Caries with Atraumatic Restorative Treatment and Topical Silver and Fluoride Agents","volume":"14","author":"Duangthip","year":"2017","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.jdent.2024.105320_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2021.103767","article-title":"Anti-bacterial and anti-microbial aging effects of resin-based sealant modified by quaternary ammonium monomers","volume":"112","author":"Huang","year":"2021","journal-title":"J Dent"},{"key":"10.1016\/j.jdent.2024.105320_bib0010","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jdent.2018.12.004","article-title":"Oral health-related quality of life of preschool children receiving silver diamine fluoride therapy: a prospective 6-month study","volume":"81","author":"Duangthip","year":"2019","journal-title":"J Dent"},{"key":"10.1016\/j.jdent.2024.105320_bib0011","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jdent.2018.08.007","article-title":"Caries-arresting effects of silver diamine fluoride and sodium fluoride on dentine caries lesions","volume":"78","author":"Yu","year":"2018","journal-title":"J Dent"},{"issue":"1","key":"10.1016\/j.jdent.2024.105320_bib0012","doi-asserted-by":"crossref","first-page":"143","DOI":"10.4012\/dmj.2018-008","article-title":"Evaluation of discoloration of sound\/demineralized root dentin with silver diamine fluoride: in-vitro study","volume":"38","author":"Sayed","year":"2019","journal-title":"Dent Mater J"},{"key":"10.1016\/j.jdent.2024.105320_bib0013","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.archoralbio.2019.03.022","article-title":"Developing biocompatible silver nanoparticles using epigallocatechin gallate for dental use","volume":"102","author":"Yin","year":"2019","journal-title":"Arch Oral Biol"},{"issue":"3","key":"10.1016\/j.jdent.2024.105320_bib0014","first-page":"152","article-title":"Cytotoxic effects of silver diamine fluoride","volume":"32","author":"Fancher","year":"2019","journal-title":"Am J Dent"},{"issue":"6","key":"10.1016\/j.jdent.2024.105320_bib0015","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.ijantimicag.2008.12.004","article-title":"Characterisation of copper oxide nanoparticles for antimicrobial applications","volume":"33","author":"Ren","year":"2009","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.jdent.2024.105320_bib0016","doi-asserted-by":"crossref","DOI":"10.1590\/1678-7757-2020-0859","article-title":"The effect of reduced glutathione on the toxicity of silver diamine fluoride in rat pulpal cells","volume":"29","author":"Kim","year":"2021","journal-title":"J Appl Oral Sci"},{"issue":"3","key":"10.1016\/j.jdent.2024.105320_bib0017","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1007\/s00253-013-5422-8","article-title":"Bioactivity, mechanism of action, and cytotoxicity of copper-based nanoparticles: a review","volume":"98","author":"Ingle","year":"2014","journal-title":"Appl Microbiol Biotechnol"},{"issue":"3","key":"10.1016\/j.jdent.2024.105320_bib0018","article-title":"Bioactive materials for caries management: a literature review","volume":"11","author":"Zhang","year":"2023","journal-title":"Dent J (Basel)"},{"issue":"17","key":"10.1016\/j.jdent.2024.105320_bib0019","doi-asserted-by":"crossref","first-page":"6912","DOI":"10.1021\/ic060175v","article-title":"Coordination chemistry of the solvated AgI and AuI ions in liquid and aqueous ammonia, trialkyl and triphenyl phosphite, and tri-n-butylphosphine solutions","volume":"45","author":"Nilsson","year":"2006","journal-title":"Inorg Chem"},{"issue":"7","key":"10.1016\/j.jdent.2024.105320_bib0020","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1177\/0022034518774783","article-title":"Arresting dentine caries with silver diamine fluoride: what's behind it?","volume":"97","author":"Mei","year":"2018","journal-title":"J Dent Res"},{"issue":"21","key":"10.1016\/j.jdent.2024.105320_bib0021","doi-asserted-by":"crossref","first-page":"13679","DOI":"10.1021\/acs.inorgchem.8b02261","article-title":"Unexpected sequential NH(3)\/H(2)O solid\/gas phase ligand exchange and quasi-intramolecular self-protonation yield [NH(4)Cu(OH)MoO(4)], a photocatalyst misidentified before as (NH(4))(2)Cu(MoO(4))(2)","volume":"57","author":"Saj\u00f3","year":"2018","journal-title":"Inorg Chem"},{"issue":"6","key":"10.1016\/j.jdent.2024.105320_bib0022","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.identj.2023.05.001","article-title":"Stability of silver and fluoride contents in silver diamine fluoride solutions","volume":"73","author":"Yan","year":"2023","journal-title":"Int Dent J"},{"key":"10.1016\/j.jdent.2024.105320_bib0023","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.2147\/IJN.S243202","article-title":"Synthesis and characterization of fluoridated silver nanoparticles and their potential as a non-staining anti-caries agent","volume":"15","author":"Yin","year":"2020","journal-title":"Int J Nanomedicine"},{"issue":"9","key":"10.1016\/j.jdent.2024.105320_bib0024","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.jdent.2013.06.009","article-title":"Inhibitory effect of silver diamine fluoride on dentine demineralisation and collagen degradation","volume":"41","author":"Mei","year":"2013","journal-title":"J Dent"},{"issue":"6","key":"10.1016\/j.jdent.2024.105320_bib0025","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.dental.2021.02.017","article-title":"Use of a novel 9.3-\u03bcm carbon dioxide laser and silver diamine fluoride: prevention of enamel demineralisation and inhibition of cariogenic bacteria","volume":"37","author":"Zhao","year":"2021","journal-title":"Dent Mater"},{"issue":"6","key":"10.1016\/j.jdent.2024.105320_bib0026","doi-asserted-by":"crossref","first-page":"e824","DOI":"10.4317\/medoral.18831","article-title":"Caries arresting effect of silver diamine fluoride on dentine carious lesion with S. mutans and L. acidophilus dual-species cariogenic biofilm","volume":"18","author":"Mei","year":"2013","journal-title":"Med Oral Patol Oral Cir Bucal"},{"issue":"9","key":"10.1016\/j.jdent.2024.105320_bib0027","article-title":"Antibacterial properties of the antimicrobial peptide gallic acid-polyphemusin I (GAPI)","volume":"12","author":"Zhang","year":"2023","journal-title":"Antibiotics (Basel)"},{"issue":"7","key":"10.1016\/j.jdent.2024.105320_bib0028","doi-asserted-by":"crossref","first-page":"4805","DOI":"10.1007\/s00784-022-04445-6","article-title":"Remineralization of caries-affected dentin and color stability of teeth restored after treatment with silver diamine fluoride and bioactive glass\u2013ceramic","volume":"26","author":"Ferreira","year":"2022","journal-title":"Clin Oral Investig"},{"key":"10.1016\/j.jdent.2024.105320_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2020.103512","article-title":"Inhibition of dentine caries using fluoride solution with silver nanoparticles: an in vitro study","volume":"103","author":"Yin","year":"2020","journal-title":"J Dent"},{"issue":"6","key":"10.1016\/j.jdent.2024.105320_bib0030","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.identj.2022.04.005","article-title":"Ion concentration of silver diamine fluoride solutions","volume":"72","author":"Yan","year":"2022","journal-title":"Int Dent J"},{"issue":"5","key":"10.1016\/j.jdent.2024.105320_bib0031","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1159\/000047469","article-title":"Effect of a solution with high fluoride concentration on remineralization of shallow and deep root surface caries in vitro","volume":"35","author":"Mukai","year":"2001","journal-title":"Caries Res"},{"issue":"2","key":"10.1016\/j.jdent.2024.105320_bib0032","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1177\/0022034517728496","article-title":"Randomized clinical trial of 12% and 38% silver diamine fluoride treatment","volume":"97","author":"Fung","year":"2018","journal-title":"J Dent Res"},{"issue":"9","key":"10.1016\/j.jdent.2024.105320_bib0033","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1177\/00220345010800091101","article-title":"The predominant aciduric microflora of root-caries lesions","volume":"80","author":"Brailsford","year":"2001","journal-title":"J Dent Res"},{"issue":"2","key":"10.1016\/j.jdent.2024.105320_bib0034","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4103\/0972-124X.84377","article-title":"Biofilms: a microbial home","volume":"15","author":"Chandki","year":"2011","journal-title":"J Indian Soc Periodontol"},{"issue":"4","key":"10.1016\/j.jdent.2024.105320_bib0035","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.bbrc.2013.11.012","article-title":"Biofilm vs. planktonic bacterial mode of growth: which do human macrophages prefer?","volume":"441","author":"Hern\u00e1ndez-Jim\u00e9nez","year":"2013","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"10.1016\/j.jdent.2024.105320_bib0036","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.dental.2023.11.006","article-title":"Silica nanoparticles containing nano-silver and chlorhexidine respond to pH to suppress biofilm acids and modulate biofilms toward a non-cariogenic composition","volume":"40","author":"Wang","year":"2024","journal-title":"Dent Mater"},{"issue":"9","key":"10.1016\/j.jdent.2024.105320_bib0037","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens11091014","article-title":"Effects of a novel, intelligent, ph-responsive resin adhesive on cariogenic biofilms in vitro","volume":"11","author":"Shi","year":"2022","journal-title":"Pathogens"},{"issue":"2","key":"10.1016\/j.jdent.2024.105320_bib0038","article-title":"A review of the common models used in mechanistic studies on demineralization-remineralization for cariology research","volume":"5","author":"Yu","year":"2017","journal-title":"Dent J (Basel)"},{"issue":"11","key":"10.1016\/j.jdent.2024.105320_bib0039","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics15112560","article-title":"Development of a novel peptide with antimicrobial and mineralising properties for caries management","volume":"15","author":"Zhang","year":"2023","journal-title":"Pharmaceutics"}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571224004895?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571224004895?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T14:09:02Z","timestamp":1729519742000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300571224004895"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":39,"alternative-id":["S0300571224004895"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2024.105320","relation":{},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Developing a novel antibacterial copper tetraamine fluoride","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2024.105320","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105320"}}