{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:10:57Z","timestamp":1790730657014,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000883","name":"University of Bristol","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000883","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome","doi-asserted-by":"publisher","award":["217065\/Z\/19\/Z"],"award-info":[{"award-number":["217065\/Z\/19\/Z"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jdent.2025.105966","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T11:53:35Z","timestamp":1751975615000},"page":"105966","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Adverse childhood experiences from birth to age 6 years and changes in dental caries experience from age 7 to 10 years"],"prefix":"10.1016","volume":"162","author":[{"given":"Noora","family":"Jawad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Golkari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1858-3713","authenticated-orcid":false,"given":"Eduardo","family":"Bernab\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.jdent.2025.105966_bib0001","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1111\/jan.12329","article-title":"Adverse childhood experiences: towards a clear conceptual meaning","volume":"70","author":"Kalmakis","year":"2014","journal-title":"J. Adv. Nurs."},{"issue":"2","key":"10.1016\/j.jdent.2025.105966_bib0002","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/s41390-019-0613-3","article-title":"Identifying adverse childhood experiences in pediatrics to prevent chronic health conditions","volume":"87","author":"Barnes","year":"2020","journal-title":"Pediatr Res."},{"key":"10.1016\/j.jdent.2025.105966_bib0003","series-title":"Applied Longitudinal Data Analysis for Epidemiology","author":"Twisk","year":"2013"},{"issue":"2","key":"10.1016\/j.jdent.2025.105966_bib0004","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/jcpp.13135","article-title":"Practitioner Review: twenty years of research with adverse childhood experience scores - Advantages, disadvantages and applications to practice","volume":"61","author":"Lacey","year":"2020","journal-title":"J. Child. Psychol. Psychiat."},{"key":"10.1016\/j.jdent.2025.105966_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.chiabu.2021.105270","article-title":"The dimensionality of adverse childhood experiences: a scoping review of ACE dimensions measurement","volume":"121","author":"Krinner","year":"2021","journal-title":"Child. Abuse Negl."},{"issue":"4","key":"10.1016\/j.jdent.2025.105966_bib0006","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0749-3797(98)00017-8","article-title":"Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study","volume":"14","author":"Felitti","year":"1998","journal-title":"Am. J. Prev. Med."},{"issue":"7S","key":"10.1016\/j.jdent.2025.105966_bib0007","doi-asserted-by":"crossref","first-page":"S51","DOI":"10.1016\/j.acap.2017.04.161","article-title":"Methods to Assess Adverse Childhood Experiences of Children and Families: toward Approaches to Promote Child Well-being in Policy and Practice","volume":"17","author":"Bethell","year":"2017","journal-title":"Acad. Pediatr."},{"issue":"3","key":"10.1016\/j.jdent.2025.105966_bib0008","first-page":"390","article-title":"Toxic Stress: effects, Prevention and Treatment","volume":"1","author":"Franke","year":"2014","journal-title":"Children (Basel)"},{"key":"10.1016\/j.jdent.2025.105966_bib0009","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.psyneuen.2019.05.002","article-title":"Extending the toxic stress model into adolescence: profiles of cortisol reactivity","volume":"107","author":"Joos","year":"2019","journal-title":"Psychoneuroendocrinology"},{"issue":"3","key":"10.1016\/j.jdent.2025.105966_bib0010","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S2352-4642(17)30024-X","article-title":"Effects of poverty on interacting biological systems underlying child development","volume":"1","author":"Jensen","year":"2017","journal-title":"Lancet Child Adolesc Health"},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0011","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12916-017-0895-4","article-title":"Biological embedding of childhood adversity: from physiological mechanisms to clinical implications","volume":"15","author":"Berens","year":"2017","journal-title":"BMC Med."},{"issue":"7","key":"10.1016\/j.jdent.2025.105966_bib0012","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1038\/s41591-023-02426-0","article-title":"Adverse childhood experiences and lifelong health","volume":"29","author":"Bhutta","year":"2023","journal-title":"Nat. Med."},{"key":"10.1016\/j.jdent.2025.105966_bib0013","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.puhe.2023.05.001","article-title":"Childhood social adversity and clustering of health risk behaviours during early adolescence in a population-based birth cohort","volume":"220","author":"Abrahamyan","year":"2023","journal-title":"Public Health."},{"key":"10.1016\/j.jdent.2025.105966_bib0014","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.pedn.2020.10.004","article-title":"Developing the Concept of Adverse Childhood Experiences: a Global Perspective","volume":"56","author":"Alhowaymel","year":"2021","journal-title":"J. Pediatr. Nurs."},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0015","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s12887-018-1037-7","article-title":"Systematic review of pediatric health outcomes associated with childhood adversity","volume":"18","author":"Oh","year":"2018","journal-title":"BMC Pediatr"},{"issue":"8","key":"10.1016\/j.jdent.2025.105966_bib0016","doi-asserted-by":"crossref","first-page":"e356","DOI":"10.1016\/S2468-2667(17)30118-4","article-title":"The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis","volume":"2","author":"Hughes","year":"2017","journal-title":"Lancet Public Health"},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0017","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1080\/15374416.2018.1496440","article-title":"Accumulation, Timing, and Duration of Early Childhood Adversity and Behavior Problems at Age 9","volume":"49","author":"Schroeder","year":"2020","journal-title":"J. Clin. Child Adolesc Psychol."},{"key":"10.1016\/j.jdent.2025.105966_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2024.107181","article-title":"Early-life adversity severity, timing, and context type are associated with SLC6A4 methylation in emerging adults: results from a prospective cohort study","volume":"170","author":"Koning","year":"2024","journal-title":"Psychoneuroendocrinology"},{"issue":"10","key":"10.1016\/j.jdent.2025.105966_bib0019","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1111\/jcpp.13986","article-title":"The relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self-harm and depression: findings from three UK prospective population-based cohorts","volume":"65","author":"Farooq","year":"2024","journal-title":"J. Child Psychol. Psychiat."},{"issue":"15","key":"10.1016\/j.jdent.2025.105966_bib0020","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1017\/S0033291718000181","article-title":"What life course theoretical models best explain the relationship between exposure to childhood adversity and psychopathology symptoms: recency, accumulation, or sensitive periods?","volume":"48","author":"Dunn","year":"2018","journal-title":"Psychol Med."},{"key":"10.1016\/j.jdent.2025.105966_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.socscimed.2019.112696","article-title":"ACEs are not equal: examining the relative impact of household dysfunction versus childhood maltreatment on mental health in adolescence","volume":"245","author":"Negriff","year":"2020","journal-title":"Soc. Sci. Med."},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0022","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1186\/s12903-023-03459-0","article-title":"A scoping review linking early childhood caries to violence, neglect, internally displaced, migrant and refugee status","volume":"23","author":"Folayan","year":"2023","journal-title":"BMC Oral Health."},{"issue":"2","key":"10.1016\/j.jdent.2025.105966_bib0023","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/jphd.12564","article-title":"The association between adverse childhood experiences and oral health: a systematic review","volume":"83","author":"Bahanan","year":"2023","journal-title":"J. Public Health Dent."},{"key":"10.1016\/j.jdent.2025.105966_bib0024","article-title":"Adverse Childhood Experiences and Oral Health of Children and Adolescents: a Systematic Review and Meta-Analysis","author":"Jural","year":"2024","journal-title":"Trauma Violence Abuse."},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0025","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1093\/ije\/dys066","article-title":"Cohort Profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort","volume":"42","author":"Fraser","year":"2013","journal-title":"Int. J. Epidemiol."},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0026","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/ije\/dys064","article-title":"Cohort Profile: the 'children of the 90s'\u2013the index offspring of the Avon Longitudinal Study of Parents and Children","volume":"42","author":"Boyd","year":"2013","journal-title":"Int. J. Epid. Emiol."},{"issue":"12","key":"10.1016\/j.jdent.2025.105966_bib0027","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143769","article-title":"Re-Examining the Association between Vitamin D and Childhood Caries","volume":"10","author":"Dudding","year":"2015","journal-title":"PLoS One."},{"issue":"9","key":"10.1016\/j.jdent.2025.105966_bib0028","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106382","article-title":"Validation of self-reported information on dental caries in a birth cohort at 18 years of age","volume":"9","author":"Silva","year":"2014","journal-title":"PLoS One."},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0029","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1600-0528.2004.00126.x","article-title":"An assessment of the validity and reliability of dental self-report items used in a National Child Nutrition Survey","volume":"32","author":"Jamieson","year":"2004","journal-title":"Commun. Dent. Oral. Epidemiol."},{"key":"10.1016\/j.jdent.2025.105966_bib0030","doi-asserted-by":"crossref","first-page":"106","DOI":"10.12688\/wellcomeopenres.14716.1","article-title":"Adverse childhood experiences in the children of the Avon Longitudinal Study of Parents and Children (ALSPAC)","volume":"3","author":"Houtepen","year":"2018","journal-title":"Wellcome Open Res."},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0031","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1046\/j.1365-3016.2001.00325.x","article-title":"ALSPAC\u2013the Avon Longitudinal Study of Parents and Children. I. Study methodology","volume":"15","author":"Golding","year":"2001","journal-title":"Paediatr. Perinat Epidemiol."},{"issue":"3","key":"10.1016\/j.jdent.2025.105966_bib0032","doi-asserted-by":"crossref","first-page":"e510","DOI":"10.1542\/peds.2006-3084","article-title":"Influences on children's oral health: a conceptual model","volume":"120","author":"Fisher-Owens","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.jdent.2025.105966_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.mehy.2024.111292","article-title":"Beyond the horizon: exploring adverse childhood experiences and their lifelong, intergenerational influence on dental caries","volume":"184","author":"Sartori","year":"2024","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.jdent.2025.105966_bib0034","series-title":"Applied Longitudinal Data Analysis","author":"Singer","year":"2003"},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0035","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1186\/s40359-024-02182-x","article-title":"Father involvement and emotion regulation during early childhood: a systematic review","volume":"12","author":"Puglisi","year":"2024","journal-title":"BMC Psychol."},{"issue":"3","key":"10.1016\/j.jdent.2025.105966_bib0036","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.clp.2018.05.001","article-title":"Neurodevelopmental Outcomes in Early Childhood","volume":"45","author":"Duncan","year":"2018","journal-title":"Clin. Perinatol."},{"issue":"8","key":"10.1016\/j.jdent.2025.105966_bib0037","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/jdn.10381","article-title":"The neuropsychology of early childhood and infancy","volume":"84","author":"Megari","year":"2024","journal-title":"Int. J. Dev. Neurosci."},{"issue":"1","key":"10.1016\/j.jdent.2025.105966_bib0038","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12903-018-0500-z","article-title":"Investigating the association between stress, saliva and dental caries: a scoping review","volume":"18","author":"Tikhonova","year":"2018","journal-title":"BMC Oral. Health"},{"key":"10.1016\/j.jdent.2025.105966_bib0039","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.jdsr.2022.11.003","article-title":"Effect of psychological stress on the oral-gut microbiota and the potential oral-gut-brain axis","volume":"58","author":"Paudel","year":"2022","journal-title":"Jpn. Dent Sci. Rev."}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571225004105?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571225004105?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T22:52:17Z","timestamp":1789771937000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300571225004105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":39,"alternative-id":["S0300571225004105"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2025.105966","relation":{},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adverse childhood experiences from birth to age 6 years and changes in dental caries experience from age 7 to 10 years","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2025.105966","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"105966"}}