{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T23:03:55Z","timestamp":1789772635036,"version":"4.0.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005847","name":"Health and Medical Research Fund","doi-asserted-by":"publisher","award":["02132216"],"award-info":[{"award-number":["02132216"]}],"id":[{"id":"10.13039\/501100005847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005847","name":"Health and Medical Research Fund","doi-asserted-by":"publisher","award":["03141636"],"award-info":[{"award-number":["03141636"]}],"id":[{"id":"10.13039\/501100005847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005847","name":"Health and Medical Research Fund","doi-asserted-by":"publisher","award":["18170492"],"award-info":[{"award-number":["18170492"]}],"id":[{"id":"10.13039\/501100005847","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jdent.2025.106058","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T06:00:18Z","timestamp":1756101618000},"page":"106058","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Papilla preservation flap surgery and endoscope-assisted subgingival debridement for Step 3 therapy: A 12-month pilot study on subgingival microbial community dynamics in deep periodontal pockets"],"prefix":"10.1016","volume":"162","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1924-4278","authenticated-orcid":false,"given":"King-Lun Dominic","family":"Ho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka-Leong Ryan","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0664-3652","authenticated-orcid":false,"given":"Wai Man","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2743-0137","authenticated-orcid":false,"given":"Maurizio S.","family":"Tonetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1979-910X","authenticated-orcid":false,"given":"Wai Keung","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jdent.2025.106058_bib0001","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1111\/jre.13173","article-title":"New putative periodontopathogens and periodontal health-associated species: a systematic review and meta-analysis","volume":"58","author":"Antezack","year":"2023","journal-title":"J Periodontal Res"},{"issue":"1","key":"10.1016\/j.jdent.2025.106058_bib0002","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/prd.12296","article-title":"The role of the microbiota in periodontal disease","volume":"83","author":"Curtis","year":"2020","journal-title":"Periodontol 2000"},{"issue":"Suppl 22","key":"10.1016\/j.jdent.2025.106058_bib0003","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/jcpe.13290","article-title":"Treatment of stage I-III periodontitis-the EFP S3 level clinical practice guideline","volume":"47","author":"Sanz","year":"2020","journal-title":"J Clin Periodontol"},{"issue":"8","key":"10.1016\/j.jdent.2025.106058_bib0004","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1111\/j.1600-051X.2005.00776.x","article-title":"Full-mouth ultrasonic debridement versus quadrant scaling and root planing as an initial approach in the treatment of chronic periodontitis","volume":"32","author":"Wennstrom","year":"2005","journal-title":"J Clin Periodontol"},{"issue":"2","key":"10.1016\/j.jdent.2025.106058_bib0005","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1902\/jop.1996.67.2.103","article-title":"Long-term evaluation of periodontal therapy: II. Incidence of sites breaking down","volume":"67","author":"Kaldahl","year":"1996","journal-title":"J Periodontol"},{"issue":"1","key":"10.1016\/j.jdent.2025.106058_bib0006","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1902\/jop.1989.60.1.67","article-title":"Scaling and root planing effectiveness: the effect of root surface access and operator experience","volume":"60","author":"Brayer","year":"1989","journal-title":"J Periodontol"},{"issue":"3","key":"10.1016\/j.jdent.2025.106058_bib0007","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1902\/jop.1987.58.3.159","article-title":"Calculus removal by scaling\/root planing with and without surgical access","volume":"58","author":"Buchanan","year":"1987","journal-title":"J Periodontol"},{"issue":"8","key":"10.1016\/j.jdent.2025.106058_bib0008","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1111\/j.1600-051X.1991.tb00096.x","article-title":"Effect of surgical and non-surgical periodontal treatment on periodontal status and subgingival microbiota","volume":"18","author":"Pedrazzoli","year":"1991","journal-title":"J Clin Periodontol"},{"issue":"6","key":"10.1016\/j.jdent.2025.106058_bib0009","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1902\/jop.1992.63.6.540","article-title":"Early effects of periodontal therapy on the detection frequency of four putative periodontal pathogens in adults","volume":"63","author":"Ali","year":"1992","journal-title":"J Periodontol"},{"issue":"2","key":"10.1016\/j.jdent.2025.106058_bib0010","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/jcpe.14075","article-title":"Endoscopic Re-instrumentation of intrabony defect-associated deep residual periodontal pockets is non-inferior to papilla preservation flap surgery: A randomized trial","volume":"52","author":"Ho","year":"2025","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.jdent.2025.106058_bib0011","doi-asserted-by":"crossref","first-page":"104907","DOI":"10.1016\/j.jdent.2024.104907","article-title":"Subgingival microbial changes in Down Syndrome adults with periodontitis after chlorhexidine adjunct non-surgical therapy and monthly recalls-A 12-month case series study","volume":"143","author":"Cheng","year":"2024","journal-title":"J Dent"},{"issue":"8","key":"10.1016\/j.jdent.2025.106058_bib0012","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/clr.13459","article-title":"Intra-oral single-site comparisons of periodontal and peri-implant microbiota in health and disease","volume":"30","author":"Yu","year":"2019","journal-title":"Clin Oral Implants Res"},{"issue":"1","key":"10.1016\/j.jdent.2025.106058_bib0013","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1600-051X.2006.01020.x","article-title":"A minimally invasive surgical technique with an enamel matrix derivative in the regenerative treatment of intra-bony defects: a novel approach to limit morbidity","volume":"34","author":"Cortellini","year":"2007","journal-title":"J Clin Periodontol"},{"issue":"4","key":"10.1016\/j.jdent.2025.106058_bib0014","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1902\/jop.1995.66.4.261","article-title":"The modified papilla preservation technique. A new surgical approach for interproximal regenerative procedures","volume":"66","author":"Cortellini","year":"1995","journal-title":"J Periodontol"},{"issue":"9","key":"10.1016\/j.jdent.2025.106058_bib0015","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1111\/jcpe.12443","article-title":"Minimally invasive non-surgical approach for the treatment of periodontal intrabony defects: a retrospective analysis","volume":"42","author":"Nibali","year":"2015","journal-title":"J Clin Periodontol"},{"issue":"9","key":"10.1016\/j.jdent.2025.106058_bib0016","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1111\/j.1600-051X.1998.tb02514.x","article-title":"A controlled multicenter study of adjunctive use of tetracycline periodontal fibers in mandibular class II furcations with persistent bleeding","volume":"25","author":"Tonetti","year":"1998","journal-title":"J Clin Periodontol"},{"issue":"3","key":"10.1016\/j.jdent.2025.106058_bib0017","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/gigascience\/gix133","article-title":"Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing","volume":"7","author":"Fang","year":"2018","journal-title":"Gigascience"},{"issue":"7","key":"10.1016\/j.jdent.2025.106058_bib0018","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nmeth.3869","article-title":"DADA2: high-resolution sample inference from Illumina amplicon data","volume":"13","author":"Callahan","year":"2016","journal-title":"Nat Methods"},{"issue":"2","key":"10.1016\/j.jdent.2025.106058_bib0019","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1600-051X.1998.tb02419.x","article-title":"Microbial complexes in subgingival plaque","volume":"25","author":"Socransky","year":"1998","journal-title":"J Clin Periodontol"},{"issue":"9","key":"10.1016\/j.jdent.2025.106058_bib0020","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1902\/jop.2011.100680","article-title":"Clinical and patient-centered outcomes after minimally invasive non-surgical or surgical approaches for the treatment of intrabony defects: a randomized clinical trial","volume":"82","author":"Ribeiro","year":"2011","journal-title":"J Periodontol"},{"issue":"1","key":"10.1016\/j.jdent.2025.106058_bib0021","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1034\/j.1600-051x.2000.027001030.x","article-title":"The effect of scaling and root planing on the clinical and microbiological parameters of periodontal diseases: 12-month results","volume":"27","author":"Cugini","year":"2000","journal-title":"J Clin Periodontol"},{"issue":"1","key":"10.1016\/j.jdent.2025.106058_bib0022","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/j.1600-051X.2005.00872.x","article-title":"P. European Research Group on, microbial colonization patterns predict the outcomes of surgical treatment of intrabony defects","volume":"33","author":"Heitz-Mayfield","year":"2006","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.jdent.2025.106058_bib0023","article-title":"Periodontal microbiology and microbial etiology of periodontal diseases: historical concepts and contemporary perspectives","volume":"2000","author":"Belibasakis","year":"2023","journal-title":"Periodontol"},{"key":"10.1016\/j.jdent.2025.106058_bib0024","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1034\/j.1600-0757.2002.280103.x","article-title":"Antimicrobial effects of mechanical debridement","volume":"28","author":"Petersilka","year":"2002","journal-title":"Periodontol 2000"},{"issue":"2","key":"10.1016\/j.jdent.2025.106058_bib0025","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/jre.13092","article-title":"Influence of periodontal surgery on the subgingival microbiome-A systematic review and meta-analysis","volume":"58","author":"Krajewski","year":"2023","journal-title":"J Periodontal Res"},{"issue":"4","key":"10.1016\/j.jdent.2025.106058_bib0026","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00162-21","article-title":"Dental plaque microbial resistomes of periodontal health and disease and their changes after scaling and root planing therapy","volume":"6","author":"Kang","year":"2021","journal-title":"mSphere"},{"issue":"11","key":"10.1016\/j.jdent.2025.106058_bib0027","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.00930-24","article-title":"Pooled analysis of oral microbiome profiles defines robust signatures associated with periodontitis","volume":"9","author":"Soueidan","year":"2024","journal-title":"mSystems"},{"issue":"2","key":"10.1016\/j.jdent.2025.106058_bib0028","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1128\/AEM.01419-06","article-title":"Molecular analysis of the subgingival microbiota in health and disease","volume":"73","author":"Ledder","year":"2007","journal-title":"Appl Environ Microbiol"},{"issue":"10","key":"10.1016\/j.jdent.2025.106058_bib0029","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1902\/jop.2001.72.10.1354","article-title":"Treponema socranskii, Treponema denticola, and Porphyromonas gingivalis are associated with severity of periodontal tissue destruction","volume":"72","author":"Takeuchi","year":"2001","journal-title":"J Periodontol"},{"issue":"1","key":"10.1016\/j.jdent.2025.106058_bib0030","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1038\/s41598-017-03804-8","article-title":"Dysbiosis in chronic periodontitis: key microbial players and interactions with the human host","volume":"7","author":"Deng","year":"2017","journal-title":"Sci Rep"}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571225005044?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571225005044?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T22:55:31Z","timestamp":1789772131000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300571225005044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":30,"alternative-id":["S0300571225005044"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2025.106058","relation":{},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Papilla preservation flap surgery and endoscope-assisted subgingival debridement for Step 3 therapy: A 12-month pilot study on subgingival microbial community dynamics in deep periodontal pockets","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2025.106058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106058"}}