{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:58:17Z","timestamp":1792684697754,"version":"4.5.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001782","name":"University of Melbourne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001782","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jdent.2026.106556","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:55:07Z","timestamp":1770252907000},"page":"106556","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Clinical efficacy of orifice barriers in endodontics: A systematic review"],"prefix":"10.1016","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2708-8834","authenticated-orcid":false,"given":"Michael E.","family":"Wylie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5788-1676","authenticated-orcid":false,"given":"James R.","family":"Fernando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Parashos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1791-0903","authenticated-orcid":false,"given":"Alastair J.","family":"Sloan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph E.A.","family":"Palamara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5621-8568","authenticated-orcid":false,"given":"Nadia","family":"Kaunein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.jdent.2026.106556_bib0002","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.jdent.2007.07.004","article-title":"A systematic review of single crowns on endodontically treated teeth","volume":"35","author":"Stavropoulou","year":"2007","journal-title":"J. Dent."},{"issue":"11","key":"10.1016\/j.jdent.2026.106556_bib0003","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/S0099-2399(89)80191-8","article-title":"Reduction in tooth stiffness as a result of endodontic and restorative procedures","volume":"15","author":"Reeh","year":"1989","journal-title":"J. Endod."},{"issue":"2","key":"10.1016\/j.jdent.2026.106556_bib0004","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0099-2399(06)81095-2","article-title":"Cuspal deflection in molars in relation to endodontic and restorative procedures","volume":"21","author":"Pantvisai","year":"1995","journal-title":"J. Endod."},{"key":"10.1016\/j.jdent.2026.106556_bib0005","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1111\/adj.12970","article-title":"Biological considerations of dental materials as orifice barriers for restoring root-filled teeth","volume":"68","author":"Wylie","year":"2023","journal-title":"Aust. Dent. J."},{"issue":"2","key":"10.1016\/j.jdent.2026.106556_bib0006","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.1016\/j.dental.2015.11.007","article-title":"Mechanisms of degradation of the hybrid layer in adhesive dentistry and therapeutic agents to improve bond durability\u2014a literature review","volume":"32","author":"Frassetto","year":"2016","journal-title":"Dent. Mater."},{"issue":"8","key":"10.1016\/j.jdent.2026.106556_bib0007","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.3390\/coatings12081094","article-title":"Degradation and stabilization of resin-dentine interfaces in polymeric dental adhesives: an updated review","volume":"12","author":"Amin","year":"2022","journal-title":"Coatings"},{"issue":"5","key":"10.1016\/j.jdent.2026.106556_bib0008","doi-asserted-by":"crossref","first-page":"203","DOI":"10.3390\/jcs9050203","article-title":"Microtensile Bond Strength of Composite Restorations: Direct vs. Semi-Direct Technique Using the Same Adhesive System","volume":"9","author":"Palma","year":"2025","journal-title":"J. Compos. Sci."},{"issue":"6","key":"10.1016\/j.jdent.2026.106556_bib0009","first-page":"e743","article-title":"Antibacterial activity of different root canal sealers against Enterococcus faecalis","volume":"9","author":"Poggio","year":"2017","journal-title":"J. Clin. Exp. Dent."},{"issue":"4","key":"10.1016\/j.jdent.2026.106556_bib0010","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1600-0722.1981.tb01689.x","article-title":"Bacteriologic evaluation of the efficacy of mechanical root canal instrumentation in endodontic therapy","volume":"89","author":"Bystr\u00f6m","year":"1981","journal-title":"Eur. J. Oral Sci."},{"issue":"1","key":"10.1016\/j.jdent.2026.106556_bib0011","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1365-2591.1985.tb00416.x","article-title":"The antibacterial action of sodium hypochlorite and EDTA in 60 cases of endodontic therapy","volume":"18","author":"Bystr\u00f6m","year":"1985","journal-title":"Int. Endod. J."},{"issue":"9","key":"10.1016\/j.jdent.2026.106556_bib0012","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0099-2399(96)80080-X","article-title":"Evaluation of coronal microleakage after endodontic treatment","volume":"22","author":"Roghanizad","year":"1996","journal-title":"J. Endod."},{"issue":"S2","key":"10.1016\/j.jdent.2026.106556_bib0013","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/iej.13897","article-title":"Factors that affect the outcomes of root canal treatment and retreatment - a reframing of the principles","volume":"56","author":"Gulabivala","year":"2023","journal-title":"Int. Endod. J."},{"issue":"9","key":"10.1016\/j.jdent.2026.106556_bib0014","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/j.joen.2023.06.019","article-title":"Prevalence of teaching apical patency and various instrumentation and obturation techniques in United States dental schools: two decades later","volume":"49","author":"Do","year":"2023","journal-title":"J. Endod."},{"key":"10.1016\/j.jdent.2026.106556_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2024.105497","article-title":"Orifice barrier preferences for coronal restoration of root filled teeth by endodontists and other dental practitioners in Australia: a questionnaire survey","volume":"153","author":"Wylie","year":"2025","journal-title":"J. Dent."},{"issue":"2","key":"10.1016\/j.jdent.2026.106556_bib0016","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/adj.12951","article-title":"Orifice barriers to prevent coronal microleakage after root canal treatment: systematic review and meta-analysis","volume":"68","author":"Chen","year":"2023","journal-title":"Aust. Dent. J."},{"key":"10.1016\/j.jdent.2026.106556_bib0017","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/iej.13713","article-title":"A critical analysis of research methods and experimental models to study root canal fillings","volume":"55","author":"De-Deus","year":"2022","journal-title":"Int. Endod. J."},{"issue":"12","key":"10.1016\/j.jdent.2026.106556_bib0018","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.joen.2007.09.004","article-title":"Wanted: a base of evidence","volume":"33","year":"2007","journal-title":"J. Endod."},{"issue":"12","key":"10.1016\/j.jdent.2026.106556_bib0019","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1111\/j.1365-2591.2012.02104.x","article-title":"Research that matters \u2013 root canal filling and leakage studies","volume":"45","author":"De-Deus","year":"2012","journal-title":"Int. Endod. J."},{"issue":"6","key":"10.1016\/j.jdent.2026.106556_bib0020","doi-asserted-by":"crossref","first-page":"588","DOI":"10.4103\/jcd.jcd_377_22","article-title":"Evaluation of coronal microleakage of intra-orifice barrier materials in endodontically treated teeth: a systematic review","volume":"25","author":"Mehta","year":"2022","journal-title":"J. Conserv. Dent. Endod."},{"issue":"9","key":"10.1016\/j.jdent.2026.106556_bib0021","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1097\/00004770-200309000-00012","article-title":"Reliability of the dye penetration studies","volume":"29","author":"Camps","year":"2003","journal-title":"J. Endod."},{"issue":"3","key":"10.1016\/j.jdent.2026.106556_bib0022","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/j.1365-2591.2010.01821.x","article-title":"Potential systematic error in laboratory experiments on microbial leakage through filled root canals: review of published articles","volume":"44","author":"Rechenberg","year":"2011","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.jdent.2026.106556_bib0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12913-014-0579-0","article-title":"SPIDER: a comparison study of specificity and sensitivity in three search tools for qualitative systematic reviews","volume":"14","author":"Methley","year":"2014","journal-title":"BMC Health Serv. Res."},{"key":"10.1016\/j.jdent.2026.106556_bib0024","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.jdent.2026.106556_bib0025","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.jdent.2026.106556_bib0026","doi-asserted-by":"crossref","first-page":"i4919","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"issue":"12","key":"10.1016\/j.jdent.2026.106556_bib0027","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-011458","article-title":"Development of a critical appraisal tool to assess the quality of cross-sectional studies (AXIS)","volume":"6","author":"Downes","year":"2016","journal-title":"BMJ Open"},{"issue":"7650","key":"10.1016\/j.jdent.2026.106556_bib0028","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.jdent.2026.106556_bib0029","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/iej.13231","article-title":"The effect of an intraorifice barrier and base under coronal restorations on the healing of apical periodontitis: a randomized controlled trial","volume":"53","author":"Kumar","year":"2020","journal-title":"Int. Endod. J."},{"issue":"7","key":"10.1016\/j.jdent.2026.106556_bib0030","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.joen.2019.03.015","article-title":"Success and survival of endodontically treated cracked teeth with radicular extensions: a 2-to 4-year prospective cohort","volume":"45","author":"Davis","year":"2019","journal-title":"J. Endod."},{"issue":"7","key":"10.1016\/j.jdent.2026.106556_bib0031","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1365-2591.2011.01872.x","article-title":"A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health","volume":"44","author":"Ng","year":"2011","journal-title":"Int. Endod. J."},{"issue":"11","key":"10.1016\/j.jdent.2026.106556_bib0032","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1111\/iej.13168","article-title":"Prognosis of root canal treatment in teeth with preoperative apical periodontitis: a study with cone-beam computed tomography and digital periapical radiography","volume":"52","author":"Restrepo-Restrepo","year":"2019","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.jdent.2026.106556_bib0033","doi-asserted-by":"crossref","DOI":"10.1155\/2024\/2234648","article-title":"Managing cracked teeth with root extension: a prospective preliminary study using Biodentine\u2122 material","volume":"2024","author":"de Toubes","year":"2024","journal-title":"Int. J. Dent."},{"issue":"8","key":"10.1016\/j.jdent.2026.106556_bib0034","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1046\/j.1365-2591.2002.00546.x","article-title":"Periapical health related to the quality of coronal restorations and root fillings","volume":"35","author":"Hommez","year":"2002","journal-title":"Int. Endod. J."},{"issue":"4","key":"10.1016\/j.jdent.2026.106556_bib0035","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1365-2591.2006.01098.x","article-title":"The relation between apical periodontitis and root-filled teeth in patients with periodontal treatment need","volume":"39","author":"Stassen","year":"2006","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.jdent.2026.106556_bib0036","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1600-9657.1986.tb00119.x","article-title":"The periapical index: a scoring system for radiographic assessment of apical periodontitis","volume":"2","author":"\u00d8rstavik","year":"1986","journal-title":"Dent. Traumatol."},{"issue":"10","key":"10.1016\/j.jdent.2026.106556_bib0037","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/j.joen.2012.06.040","article-title":"Lesion progression in post-treatment persistent endodontic lesions","volume":"38","author":"Yu","year":"2012","journal-title":"J. Endod."},{"issue":"1","key":"10.1016\/j.jdent.2026.106556_bib0038","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jclinepi.2006.03.012","article-title":"Quality criteria were proposed for measurement properties of health status questionnaires","volume":"60","author":"Terwee","year":"2007","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.jdent.2026.106556_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2023.104409","article-title":"Clinical longevity of extensive direct resin composite restorations after amalgam replacement with a mean follow-up of 15 years","volume":"130","author":"Hofsteenge","year":"2023","journal-title":"J. Dent."},{"issue":"10","key":"10.1016\/j.jdent.2026.106556_bib0040","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1177\/0022034510376071","article-title":"12-year survival of composite vs. amalgam restorations","volume":"89","author":"Opdam","year":"2010","journal-title":"J. Dent. Res."},{"issue":"4","key":"10.1016\/j.jdent.2026.106556_bib0041","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.dental.2022.02.009","article-title":"Clinical performance of posterior resin composite restorations after up to 33 years","volume":"38","author":"Rodolpho","year":"2022","journal-title":"Dent. Mater."},{"issue":"11","key":"10.1016\/j.jdent.2026.106556_bib0042","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1046\/j.1365-2591.2003.00721.x","article-title":"Bacterial status in root-filled teeth exposed to the oral environment by loss of restoration and fracture or caries\u2013a histobacteriological study of treated cases","volume":"36","author":"Ricucci","year":"2003","journal-title":"Int. Endod. J."},{"issue":"7","key":"10.1016\/j.jdent.2026.106556_bib0043","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1111\/iej.13736","article-title":"Outcomes of primary root canal therapy: An updated systematic review of longitudinal clinical studies published between 2003 and 2020","volume":"55","author":"Burns","year":"2022","journal-title":"Int. Endod. J."},{"key":"10.1016\/j.jdent.2026.106556_bib0044","doi-asserted-by":"crossref","first-page":"e216","DOI":"10.1111\/iej.12844","article-title":"Pooled analysis of 1-year recall data from three root canal treatment outcome studies undertaken using cone beam computed tomography","volume":"51","author":"Al-Nuaimi","year":"2018","journal-title":"Int. Endod. J."},{"issue":"4","key":"10.1016\/j.jdent.2026.106556_bib0045","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1590\/S0103-64402007000400002","article-title":"Periapical tissue healing after post space preparation with or without use of a protection plug and root canal exposure to the oral environment: study in dogs","volume":"18","author":"Holland","year":"2007","journal-title":"Braz. Dent. J."},{"issue":"7","key":"10.1016\/j.jdent.2026.106556_bib0046","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1097\/00004770-200307000-00004","article-title":"Periapical inflammation affecting coronally-inoculated dog teeth with root fillings augmented by white MTA orifice plugs","volume":"29","author":"Mah","year":"2003","journal-title":"J. Endod."},{"issue":"6","key":"10.1016\/j.jdent.2026.106556_bib0047","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.joen.2005.09.005","article-title":"Effect of orifice plugs on periapical inflammation in dogs","volume":"32","author":"Yamauchi","year":"2006","journal-title":"J. Endod."},{"issue":"4","key":"10.1016\/j.jdent.2026.106556_bib0048","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1017\/S0963180115000067","article-title":"The ethical challenges of animal research: Honoring Henry Beecher\u2019s approach to moral problems","volume":"24","author":"Ferdowsian","year":"2015","journal-title":"Camb. Q. Healthc. Ethics"},{"issue":"21","key":"10.1016\/j.jdent.2026.106556_bib0049","first-page":"28","article-title":"Trading up in animal research: transitioning from rodents to primates or even pigs involves more than just larger accommodations","volume":"19","author":"Flores","year":"2005","journal-title":"The Scientist"},{"issue":"2","key":"10.1016\/j.jdent.2026.106556_bib0050","doi-asserted-by":"crossref","first-page":"378","DOI":"10.14219\/jada.archive.1971.0068","article-title":"The physical and biologic properties of cavit","volume":"82","author":"Widerman","year":"1971","journal-title":"J. Am. Dent. Assoc."},{"key":"10.1016\/j.jdent.2026.106556_bib0051","unstructured":"National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, The Belmont report: Ethical principles and guidelines for the protection of human subjects of research, 1979. https:\/\/www.hhs.gov\/ohrp\/regulations-and-policy\/belmont-report\/index.html. (Accessed November 20, 2024)."},{"issue":"1","key":"10.1016\/j.jdent.2026.106556_bib0052","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1046\/j.1365-2702.2003.00662.x","article-title":"Hierarchy of evidence: a framework for ranking evidence evaluating healthcare interventions","volume":"12","author":"Evans","year":"2003","journal-title":"J. Clin. Nurs."},{"issue":"1","key":"10.1016\/j.jdent.2026.106556_bib0053","doi-asserted-by":"crossref","first-page":"S65","DOI":"10.1016\/j.chest.2020.03.012","article-title":"Cross-sectional studies: strengths, weaknesses, and recommendations","volume":"158","author":"Wang","year":"2020","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.jdent.2026.106556_bib0054","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/0030-4220(72)90473-2","article-title":"Endodontic success\u2014who's reading the radiograph?, Oral Surg","volume":"33","author":"Goldman","year":"1972","journal-title":"Oral Med. Oral Pathol."},{"issue":"6","key":"10.1016\/j.jdent.2026.106556_bib0055","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1046\/j.1365-2591.2000.00381.x","article-title":"Periapical status and quality of root fillings and coronal restorations in a Danish population","volume":"33","author":"Kirkevang","year":"2000","journal-title":"Int. Endod. J."},{"issue":"4","key":"10.1016\/j.jdent.2026.106556_bib0056","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.joen.2017.12.025","article-title":"12-month success of cracked teeth treated with orthograde root canal treatment","volume":"44","author":"Krell","year":"2018","journal-title":"J. Endod."},{"issue":"10","key":"10.1016\/j.jdent.2026.106556_bib0057","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1111\/iej.13598","article-title":"Repair of teeth with cracks in crowns and roots: an observational clinical study","volume":"54","author":"Malentacca","year":"2021","journal-title":"Int. Endod. J."},{"issue":"2","key":"10.1016\/j.jdent.2026.106556_bib0058","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.joen.2015.11.011","article-title":"Decision making for retention of endodontically treated posterior cracked teeth: a 5-year follow-up study","volume":"42","author":"Sim","year":"2016","journal-title":"J. Endod."},{"issue":"3","key":"10.1016\/j.jdent.2026.106556_bib0059","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/iej.14186","article-title":"Position statement on longitudinal cracks and fractures of teeth","volume":"58","author":"Patel","year":"2025","journal-title":"Int. Endod. J."},{"issue":"3","key":"10.1016\/j.jdent.2026.106556_bib0060","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.joen.2007.10.017","article-title":"Treatment outcome in endodontics: the Toronto study\u2014phase 4: initial treatment","volume":"34","author":"de Chevigny","year":"2008","journal-title":"J. Endod."},{"issue":"3","key":"10.1016\/j.jdent.2026.106556_bib0061","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/j.1365-2591.2009.01671.x","article-title":"Tooth survival following non-surgical root canal treatment: a systematic review of the literature","volume":"43","author":"Ng","year":"2010","journal-title":"Int. Endod. J."},{"issue":"7","key":"10.1016\/j.jdent.2026.106556_bib0062","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/j.1708-8240.2003.tb00963.x","article-title":"Definitive diagnosis of early enamel and dentinal cracks based on microscopic evaluation","volume":"15","author":"Clark","year":"2003","journal-title":"J. Esthet. Restor. Dent."},{"issue":"8","key":"10.1016\/j.jdent.2026.106556_bib0063","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1902\/jop.1988.59.8.493","article-title":"Ultrastructural observations on bacterial invasion in cementum and radicular dentin of periodontally diseased human teeth","volume":"59","author":"Adriaens","year":"1988","journal-title":"J. Periodontol."},{"issue":"6","key":"10.1016\/j.jdent.2026.106556_bib0064","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.joen.2023.04.005","article-title":"Factors affecting the decision-making of direct pulp capping procedures among dental practitioners: a multinational survey from 16 countries with meta-analysis","volume":"49","author":"Hatipo\u011flu","year":"2023","journal-title":"J. Endod."}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571226002290?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571226002290?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T06:22:45Z","timestamp":1784787765000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300571226002290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":63,"alternative-id":["S0300571226002290"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2026.106556","relation":{},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical efficacy of orifice barriers in endodontics: A systematic review","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2026.106556","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106556"}}