{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:53:59Z","timestamp":1786121639359,"version":"build-2736575974"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000764","name":"King's College London","doi-asserted-by":"publisher","award":["20\/EE\/0241"],"award-info":[{"award-number":["20\/EE\/0241"]}],"id":[{"id":"10.13039\/501100000764","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jdent.2026.106871","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T20:09:28Z","timestamp":1782850168000},"page":"106871","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Multiomics analyses in young grade C molar incisor pattern periodontitis"],"prefix":"10.1016","volume":"174","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-7430-8864","authenticated-orcid":false,"given":"Meaad M.","family":"Alamri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"Proctor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Garcia-Guevara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrien Le","family":"Guennec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2778-9756","authenticated-orcid":false,"given":"Giuseppe","family":"Mainas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Shoaie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7750-5010","authenticated-orcid":false,"given":"Luigi","family":"Nibali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jdent.2026.106871_bib0001","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2334\/josnusd.57.87","article-title":"Impact of the severity of chronic periodontal disease on quality of life","volume":"57","author":"Meusel","year":"2015","journal-title":"J. Oral Sci."},{"issue":"10","key":"10.1016\/j.jdent.2026.106871_bib0002","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1177\/0022034512456039","article-title":"Microbiological characterization in children with aggressive periodontitis","volume":"91","author":"Shaddox","year":"2012","journal-title":"J. Dent. Res."},{"issue":"Suppl 20","key":"10.1016\/j.jdent.2026.106871_bib0003","first-page":"S162","article-title":"Periodontitis: consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45","author":"Papapanou","year":"2018","journal-title":"J. Clin. Periodontol."},{"issue":"3","key":"10.1016\/j.jdent.2026.106871_bib0004","doi-asserted-by":"crossref","first-page":"413","DOI":"10.4161\/viru.27864","article-title":"The role of metagenomics in understanding the human microbiome in health and disease","volume":"5","author":"Mart\u00edn","year":"2014","journal-title":"Virulence"},{"key":"10.1016\/j.jdent.2026.106871_bib0005","series-title":"Molecular Biology","first-page":"270","article-title":"Chapter 9 - genomics and systems biology","author":"Clark","year":"2019"},{"issue":"9","key":"10.1016\/j.jdent.2026.106871_bib0006","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.1128\/JCM.00729-13","article-title":"A consortium of Aggregatibacter actinomycetemcomitans, Streptococcus parasanguinis, and Filifactor alocis is present in sites prior to bone loss in a longitudinal study of localized aggressive periodontitis","volume":"51","author":"Fine","year":"2013","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jdent.2026.106871_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2021.103912","article-title":"Patterns of subgingival microbiota in different periodontal phenotypes","volume":"117","author":"Nibali","year":"2022","journal-title":"J. Dent."},{"issue":"8","key":"10.1016\/j.jdent.2026.106871_bib0008","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1111\/jcpe.13330","article-title":"Differences in the periodontal microbiome of successfully treated and persistent aggressive periodontitis","volume":"47","author":"Nibali","year":"2020","journal-title":"J. Clin. Periodontol."},{"issue":"9","key":"10.1016\/j.jdent.2026.106871_bib0009","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.3390\/molecules27092864","article-title":"Metabolomics research in periodontal disease by mass spectrometry","volume":"27","author":"Tsuchida","year":"2022","journal-title":"Molecules"},{"issue":"6","key":"10.1016\/j.jdent.2026.106871_bib0010","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1007\/s11306-015-0840-5","article-title":"The human saliva metabolome","volume":"11","author":"Dame","year":"2015","journal-title":"Metabolomics"},{"issue":"2","key":"10.1016\/j.jdent.2026.106871_bib0011","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3390\/metabo10020047","article-title":"Salivary metabolomics: from diagnostic biomarker discovery to investigating biological function","volume":"10","author":"Gardner","year":"2020","journal-title":"Metabolites"},{"issue":"1","key":"10.1016\/j.jdent.2026.106871_bib0012","doi-asserted-by":"crossref","DOI":"10.1080\/20002297.2019.1617014","article-title":"Determining bacterial and host contributions to the human salivary metabolome","volume":"11","author":"Gardner","year":"2019","journal-title":"J. Oral Microbiol."},{"issue":"4","key":"10.1016\/j.jdent.2026.106871_bib0013","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nrm3314","article-title":"Innovation: metabolomics: the apogee of the omics trilogy","volume":"13","author":"Patti","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jdent.2026.106871_bib0014","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1146\/annurev-immunol-071219-125715","article-title":"Microbiota metabolites in health and disease","volume":"38","author":"McCarville","year":"2020","journal-title":"Annu. Rev. Immunol."},{"issue":"5","key":"10.1016\/j.jdent.2026.106871_bib0015","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/s41580-022-00572-w","article-title":"Metabolites as signalling molecules","volume":"24","author":"Baker","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"9","key":"10.1016\/j.jdent.2026.106871_bib0016","doi-asserted-by":"crossref","first-page":"4264","DOI":"10.1021\/pr900344m","article-title":"Individual human phenotypes in metabolic space and time","volume":"8","author":"Bernini","year":"2009","journal-title":"J. Proteome Res."},{"issue":"1","key":"10.1016\/j.jdent.2026.106871_bib0017","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/prd.12316","article-title":"Host-microbe interactions: profiles in the transcriptome, the proteome, and the metabolome","volume":"82","author":"Nguyen","year":"2020","journal-title":"Periodontol."},{"issue":"11","key":"10.1016\/j.jdent.2026.106871_bib0018","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11306-022-01940-5","article-title":"Periodontal disease metabolomics signatures from different biofluids: a systematic review","volume":"18","author":"Brito","year":"2022","journal-title":"Metabolomics"},{"key":"10.1016\/j.jdent.2026.106871_bib0019","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.728585","article-title":"Metagenomic and metatranscriptomic insight into oral biofilms in periodontitis and related systemic diseases","volume":"12","author":"Huang","year":"2021","journal-title":"Front. Microbiol."},{"issue":"8","key":"10.1016\/j.jdent.2026.106871_bib0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0182767","article-title":"Identification of a discriminative metabolomic fingerprint of potential clinical relevance in saliva of patients with periodontitis using 1H nuclear magnetic resonance (NMR) spectroscopy","volume":"12","author":"Rzeznik","year":"2017","journal-title":"PLoS. One"},{"issue":"12","key":"10.1016\/j.jdent.2026.106871_bib0021","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1002\/JPER.18-0097","article-title":"Analysis of salivary phenotypes of generalized aggressive and chronic periodontitis through nuclear magnetic resonance-based metabolomics","volume":"89","author":"Romano","year":"2018","journal-title":"J. Periodontol."},{"issue":"3","key":"10.1016\/j.jdent.2026.106871_bib0022","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s11306-011-0331-2","article-title":"Metabonomic analysis of saliva reveals generalized chronic periodontitis signature","volume":"8","author":"Aimetti","year":"2012","journal-title":"Metabolomics."},{"issue":"5","key":"10.1016\/j.jdent.2026.106871_bib0023","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1111\/jre.12579","article-title":"Analysis of metabolic profiles of generalized aggressive periodontitis","volume":"53","author":"Chen","year":"2018","journal-title":"J. Periodontal. Res."},{"issue":"4","key":"10.1016\/j.jdent.2026.106871_bib0024","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/jre.70077","article-title":"Molar\u2013Incisor and generalized grade C periodontitis: distinct microbiome\u2013Immune interactions suggest divergent pathogenesis","volume":"61","author":"Stolf","year":"2026","journal-title":"J. Periodont. Res."},{"issue":"4","key":"10.1016\/j.jdent.2026.106871_bib0025","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The strengthening the reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","journal-title":"J. Clin. Epidemiol."},{"issue":"Suppl 20","key":"10.1016\/j.jdent.2026.106871_bib0026","first-page":"S1","article-title":"A new classification scheme for periodontal and peri-implant diseases and conditions - introduction and key changes from the 1999 classification","volume":"45","author":"Caton","year":"2018","journal-title":"J. Clin. Periodontol."},{"issue":"3","key":"10.1016\/j.jdent.2026.106871_bib0027","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1096\/fasebj.13.3.563","article-title":"Immunomodulatory effects of glycine on LPS-treated monocytes: reduced TNF-alpha production and accelerated IL-10 expression","volume":"13","author":"Spittler","year":"1999","journal-title":"FASEB J."},{"issue":"8","key":"10.1016\/j.jdent.2026.106871_bib0028","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1111\/j.1399-6576.2005.00786.x","article-title":"Glycine\u2013an important neurotransmitter and cytoprotective agent","volume":"49","author":"Gundersen","year":"2005","journal-title":"Acta Anaesthesiol. Scand."},{"issue":"3","key":"10.1016\/j.jdent.2026.106871_bib0029","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s00726-013-1493-1","article-title":"Glycine metabolism in animals and humans: implications for nutrition and health","volume":"45","author":"Wang","year":"2013","journal-title":"Amino Acids."},{"issue":"12","key":"10.1016\/j.jdent.2026.106871_bib0030","doi-asserted-by":"crossref","first-page":"3977","DOI":"10.3390\/jcm9123977","article-title":"Changes in the salivary metabolic profile of generalized periodontitis patients after non-surgical periodontal therapy: a metabolomic analysis using nuclear magnetic resonance spectroscopy","volume":"9","author":"Citterio","year":"2020","journal-title":"J. Clin. Med."},{"issue":"4","key":"10.1016\/j.jdent.2026.106871_bib0031","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1093\/bioinformatics\/btg033","article-title":"Subnetwork hierarchies of biochemical pathways","volume":"19","author":"Holme","year":"2003","journal-title":"Bioinformatics"},{"issue":"1","key":"10.1016\/j.jdent.2026.106871_bib0032","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0174-173X(83)80047-8","article-title":"Connective tissues of the periodontium: a summary of current work","volume":"3","author":"Narayanan","year":"1983","journal-title":"Coll. Relat. Res."},{"issue":"9","key":"10.1016\/j.jdent.2026.106871_bib0033","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/0003-9969(87)90032-X","article-title":"Free amino-acid content of wax-stimulated human whole saliva as related to periodontal disease","volume":"32","author":"Syrj\u00e4nen","year":"1987","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.jdent.2026.106871_bib0034","unstructured":"N.N. Abumrad, A. Barbul, The use of arginine in clinical practice, in: Metabolic and Therapeutic Aspects of Amino Acids in Clinical Nutrition, 2004, pp. 595\u2013611."},{"issue":"12","key":"10.1016\/j.jdent.2026.106871_bib0035","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1007\/s00726-021-02981-1","article-title":"Proline metabolism and transport in retinal health and disease","volume":"53","author":"Du","year":"2021","journal-title":"Amino Acids."},{"issue":"1","key":"10.1016\/j.jdent.2026.106871_bib0036","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1600-0765.2004.00767.x","article-title":"Chronic glycine treatment inhibits ligature-induced periodontal disease in Wistar rats","volume":"40","author":"Breivik","year":"2005","journal-title":"J. Periodontal. Res."},{"issue":"8","key":"10.1016\/j.jdent.2026.106871_bib0037","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1111\/jcpe.13330","article-title":"Differences in the periodontal microbiome of successfully treated and persistent aggressive periodontitis","volume":"47","author":"Nibali","year":"2020","journal-title":"J. Clin. Periodontol."},{"key":"10.1016\/j.jdent.2026.106871_bib0038","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3389\/fcimb.2019.00053","article-title":"Comparison of subgingival and buccal mucosa microbiome in chronic and aggressive periodontitis: a pilot study","volume":"9","author":"Wei","year":"2019","journal-title":"Front. Cell Infect. Microbiol."},{"issue":"6","key":"10.1016\/j.jdent.2026.106871_bib0039","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1177\/0022034516634619","article-title":"Levels of candidate periodontal pathogens in subgingival biofilm","volume":"95","author":"Oliveira","year":"2016","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2026.106871_bib0040","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.archoralbio.2019.02.012","article-title":"Subgingival microbiome in Chinese patients with generalized aggressive periodontitis compared to healthy controls","volume":"101","author":"Cui","year":"2019","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.jdent.2026.106871_bib0041","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.archoralbio.2019.01.015","article-title":"Comparison of the oral microbiome of patients with generalized aggressive periodontitis and periodontitis-free subjects","volume":"99","author":"Schulz","year":"2019","journal-title":"Arch. Oral Biol."},{"issue":"11","key":"10.1016\/j.jdent.2026.106871_bib0042","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01030-24","article-title":"Salivary microbiota reflecting changes in subgingival microbiota","volume":"12","author":"Jung","year":"2024","journal-title":"Microbiol. Spectr."},{"issue":"10","key":"10.1016\/j.jdent.2026.106871_bib0043","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1177\/0022034512456039","article-title":"Microbiological characterization in children with aggressive periodontitis","volume":"91","author":"Shaddox","year":"2012","journal-title":"J. Dent. Res."},{"issue":"2","key":"10.1016\/j.jdent.2026.106871_bib0044","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1600-0765.2012.01516.x","article-title":"Prevalence and diversity of Synergistetes taxa in periodontal health and disease","volume":"48","author":"You","year":"2013","journal-title":"J. Periodont. Res."},{"issue":"6","key":"10.1016\/j.jdent.2026.106871_bib0045","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1631\/jzus.B1000056","article-title":"Leptotrichia hongkongensis sp. nov., a novel Leptotrichia species with the oral cavity as its natural reservoir","volume":"11","author":"Woo","year":"2010","journal-title":"J. Zhejiang. Univ. Sci. B"},{"issue":"2","key":"10.1016\/j.jdent.2026.106871_bib0046","article-title":"Insights into the evolution of host association through the isolation and characterization of a novel human periodontal pathobiont","volume":"9","author":"Cross","year":"2018","journal-title":"Desulfobulbus. Oralis., mBio"},{"issue":"6","key":"10.1016\/j.jdent.2026.106871_bib0047","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1007\/s00726-011-0962-7","article-title":"Mechanism underlying the antioxidant activity of taurine: prevention of mitochondrial oxidant production","volume":"42","author":"Jong","year":"2012","journal-title":"Amino Acids."},{"key":"10.1016\/j.jdent.2026.106871_bib0048","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/978-1-4615-0077-3_38","article-title":"Taurine concentration in human blood peripheral lymphocytes: major depression and treatment with the antidepressant mirtazapine","volume":"526","author":"Lima","year":"2003","journal-title":"Adv. Exp. Med. Biol."},{"issue":"2","key":"10.1016\/j.jdent.2026.106871_bib0049","first-page":"228","article-title":"Evaluation of the efficacy of taurine as an antioxidant in the management of patients with chronic periodontitis","volume":"11","author":"Sree","year":"2014","journal-title":"Dent. Res. J."},{"key":"10.1016\/j.jdent.2026.106871_bib0050","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1146\/annurev-bioeng-071516-044546","article-title":"Glutaminolysis: a hallmark of cancer metabolism","volume":"19","author":"Yang","year":"2017","journal-title":"Annu Rev. Biomed. Eng."},{"issue":"8","key":"10.1016\/j.jdent.2026.106871_bib0051","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1289\/ehp.1104650","article-title":"Selective pressure of antibiotic pollution on bacteria of importance to public health","volume":"120","author":"Tello","year":"2012","journal-title":"Environ. Health Perspect."},{"issue":"9","key":"10.1016\/j.jdent.2026.106871_bib0052","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1038\/s41423-024-01192-4","article-title":"The immunology of sickness metabolism","volume":"21","author":"Wensveen","year":"2024","journal-title":"Cell Mol. Immunol."},{"issue":"1","key":"10.1016\/j.jdent.2026.106871_bib0053","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s40001-022-00735-7","article-title":"Evaluation of L-arginine supplement on the growth rate, biofilm formation, and antibiotic susceptibility in Streptococcus mutans","volume":"27","author":"Vaziriamjad","year":"2022","journal-title":"Eur. J. Med. Res."},{"key":"10.1016\/j.jdent.2026.106871_bib0054","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2022.838173","article-title":"Exploring the pharmacological potential of metformin for neurodegenerative diseases","volume":"14","author":"Du","year":"2022","journal-title":"Front. Aging Neurosci."},{"issue":"8","key":"10.1016\/j.jdent.2026.106871_bib0055","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/s41574-023-00833-4","article-title":"Metformin: update on mechanisms of action and repurposing potential","volume":"19","author":"Foretz","year":"2023","journal-title":"Nat. Rev. Endocrinol."},{"issue":"1","key":"10.1016\/j.jdent.2026.106871_bib0056","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1186\/s12967-023-04456-1","article-title":"Repurposing metformin for periodontal disease management as a form of oral-systemic preventive medicine","volume":"21","author":"Neves","year":"2023","journal-title":"J. Transl. Med."}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571226005415?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571226005415?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T06:40:34Z","timestamp":1786084834000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300571226005415"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":56,"alternative-id":["S0300571226005415"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2026.106871","relation":{},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiomics analyses in young grade C molar incisor pattern periodontitis","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2026.106871","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106871"}}