{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:00:14Z","timestamp":1790776814464,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,8,7]],"date-time":"2027-08-07T00:00:00Z","timestamp":1817596800000},"content-version":"am","delay-in-days":249,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100010393","name":"University of Maryland Baltimore School of Dentistry","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010393","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dentistry"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.jdent.2026.106942","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T15:42:16Z","timestamp":1785512536000},"page":"106942","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Bioactive orthodontic adhesive for clear-aligner attachments: antibacterial activity, ion release, and bonding performance"],"prefix":"10.1016","volume":"175","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2135-6653","authenticated-orcid":false,"given":"Heba","family":"Alqarni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchan","family":"Seol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3524-2515","authenticated-orcid":false,"given":"Ibrahim","family":"Ba-Armah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7197-8239","authenticated-orcid":false,"given":"Nader","family":"Almutairi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7850-9961","authenticated-orcid":false,"given":"Mohammad","family":"Alenizy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazeed","family":"Altamimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayman","family":"Altamimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dwayne D.","family":"Arola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W.","family":"Oates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3383-8956","authenticated-orcid":false,"given":"Jirun","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7961-3787","authenticated-orcid":false,"given":"Michael D.","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hockin H.K.","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdent.2026.106942_bib0001","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.3390\/medicina59101773","article-title":"Orthodontic aligners: current perspectives for the modern orthodontic office","volume":"59","author":"Kau","year":"2023","journal-title":"Medicina"},{"key":"10.1016\/j.jdent.2026.106942_bib0002","doi-asserted-by":"crossref","DOI":"10.4103\/jpbs.jpbs_1424_24","article-title":"Assessment of patient-reported outcomes in the use of clear aligners compared to conventional fixed braces","author":"Subbaraju","year":"2025","journal-title":"J. Pharm. Bioallied. Sci."},{"key":"10.1016\/j.jdent.2026.106942_bib0003","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3390\/ma15020533","article-title":"Effects of composite attachments on orthodontic clear aligners therapy: a systematic review","volume":"15","author":"Nucera","year":"2022","journal-title":"Materials"},{"key":"10.1016\/j.jdent.2026.106942_bib0004","doi-asserted-by":"crossref","first-page":"177","DOI":"10.4274\/TurkJOrthod.2025.2025.7","article-title":"Clear aligner attachments: a comprehensive review","volume":"38","author":"Yang\u0131n","year":"2025","journal-title":"Turk. J. Orthod."},{"key":"10.1016\/j.jdent.2026.106942_bib0005","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4103\/2278-0203.115081","article-title":"Risk factors and management of white spot lesions in orthodontics","volume":"2","author":"Srivastava","year":"2013","journal-title":"J. Orthod. Sci."},{"key":"10.1016\/j.jdent.2026.106942_bib0006","doi-asserted-by":"crossref","first-page":"368","DOI":"10.2478\/aoj-2022-0035","article-title":"Prevalence of white spot lesions during clear aligner therapy: a systematic review","volume":"38","author":"Abay","year":"2022","journal-title":"Australas. Orthod. J."},{"key":"10.1016\/j.jdent.2026.106942_bib0007","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s12903-023-03720-6","article-title":"White spot lesions: diagnosis and treatment - a systematic review","volume":"24","author":"Lopes","year":"2024","journal-title":"BMC Oral Health"},{"key":"10.1016\/j.jdent.2026.106942_bib0008","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.dental.2017.10.007","article-title":"High performance dental resin composites with hydrolytically stable monomers","volume":"34","author":"Wang","year":"2018","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2026.106942_bib0009","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1177\/0022034519895269","article-title":"High-performance dental adhesives containing an ether-based monomer","volume":"99","author":"Yamauchi","year":"2020","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2026.106942_bib0011","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.3390\/coatings14111370","article-title":"Novel antibacterial resin coating for dental provisional crowns to suppress biofilms and inhibit secondary caries","volume":"14","author":"Ba-Armah","year":"2024","journal-title":"Coatings"},{"key":"10.1016\/j.jdent.2026.106942_bib0012","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3390\/bioengineering7030083","article-title":"Emerging contact-killing antibacterial strategies for developing anti-biofilm dental polymeric restorative materials","volume":"7","author":"Mitwalli","year":"2020","journal-title":"Bioengineering"},{"key":"10.1016\/j.jdent.2026.106942_bib0013","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1177\/0022034515571416","article-title":"Effect of antibacterial dental adhesive on multispecies biofilms formation","volume":"94","author":"Zhang","year":"2015","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2026.106942_bib0014","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/S0109-5641(02)00105-7","article-title":"Mechanical properties and biochemical activity of remineralizing resin-based Ca\u2013PO4 cements","volume":"19","author":"Dickens","year":"2003","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2026.106942_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2020.103406","article-title":"Novel low-shrinkage-stress nanocomposite with remineralization and antibacterial abilities to protect marginal enamel under biofilm","volume":"99","author":"Bhadila","year":"2020","journal-title":"J. Dent."},{"key":"10.1016\/j.jdent.2026.106942_bib0016","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.actbio.2020.07.057","article-title":"Bioactive low-shrinkage-stress nanocomposite suppresses S. mutans biofilm and preserves tooth dentin hardness","volume":"114","author":"Bhadila","year":"2020","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jdent.2026.106942_bib0017","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.dental.2021.08.014","article-title":"Is the presence of 10-MDP associated to higher bonding performance for self-etching adhesive systems? A meta-analysis of in vitro studies","volume":"37","author":"Fehrenbach","year":"2021","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2026.106942_bib0018","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3390\/ma12050790","article-title":"10-MDP based dental adhesives: adhesive interface characterization and adhesive stability-a systematic review","volume":"12","author":"Carrilho","year":"2019","journal-title":"Materials"},{"key":"10.1016\/j.jdent.2026.106942_bib0019","doi-asserted-by":"crossref","DOI":"10.3389\/froh.2025.1630019","article-title":"Novel antimicrobial and bioactive resin-based clear aligner attachment orthodontic materials","volume":"6","author":"Alqarni","year":"2025","journal-title":"Front. Oral Health"},{"key":"10.1016\/j.jdent.2026.106942_bib0020","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1021\/acs.biomac.5b01069","article-title":"Preparation of dental resins resistant to enzymatic and hydrolytic degradation in oral environments","volume":"16","author":"Gonzalez-Bonet","year":"2015","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.jdent.2026.106942_bib0021","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jdent.2013.01.004","article-title":"Dental primer and adhesive containing a new antibacterial quaternary ammonium monomer dimethylaminododecyl methacrylate","volume":"41","author":"Cheng","year":"2013","journal-title":"J. Dent."},{"key":"10.1016\/j.jdent.2026.106942_bib0022","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00784-021-04002-7","article-title":"Novel calcium phosphate ion-rechargeable and antibacterial adhesive to inhibit dental caries","volume":"26","author":"al-Qarni","year":"2022","journal-title":"Clin. Oral Investig."},{"key":"10.1016\/j.jdent.2026.106942_bib0023","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1021\/acs.jchemed.8b00659","article-title":"Analysis of double bond conversion of photopolymerizable monomers by FTIR-ATR spectroscopy","volume":"96","author":"Herrera-Gonz\u00e1lez","year":"2019","journal-title":"J. Chem. Educ."},{"key":"10.1016\/j.jdent.2026.106942_bib0024","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0109-5641(00)00062-2","article-title":"Determination of double bond conversion in dental resins by near infrared spectroscopy","volume":"17","author":"Stansbury","year":"2001","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2026.106942_bib0025","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.jdent.2014.07.006","article-title":"Novel antibacterial orthodontic cement containing quaternary ammonium monomer dimethylaminododecyl methacrylate","volume":"42","author":"Melo","year":"2014","journal-title":"J. Dent."},{"key":"10.1016\/j.jdent.2026.106942_bib0026","series-title":"Dentistry: Root Canal Sealing Materials","year":"2012"},{"key":"10.1016\/j.jdent.2026.106942_bib0027","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.3390\/ijms26062490","article-title":"Novel bioactive resin coating with calcium phosphate nanoparticles for antibacterial and remineralization abilities to combat tooth root caries","volume":"26","author":"Almutairi","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jdent.2026.106942_bib0028","first-page":"99","article-title":"Chapter 4 in vitro biofilm models","volume":"69","author":"McBain","year":"2009"},{"key":"10.1016\/j.jdent.2026.106942_bib0029","first-page":"853","article-title":"Dental plaque microcosm biofilm behavior on calcium phosphate nanocomposite with quaternary ammonium","volume":"28","author":"Cheng","year":"2012","journal-title":"Dent. Mater. Off. Publ. Acad. Dent. Mater."},{"key":"10.1016\/j.jdent.2026.106942_bib0030","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1177\/154405910708600415","article-title":"Effects of calcium phosphate nanoparticles on Ca-PO4 composite","volume":"86","author":"Xu","year":"2007","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2026.106942_bib0031","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/s00784-025-06312-6","article-title":"Effects of different remineralization agents on shear bond strength of orthodontic brackets: in vitro study","volume":"29","author":"Oda","year":"2025","journal-title":"Clin. Oral Investig."},{"key":"10.1016\/j.jdent.2026.106942_bib0032","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/0301228X.1975.11743666","article-title":"A review of direct orthodontic bonding","volume":"2","author":"Reynolds","year":"1975","journal-title":"Br. J. Orthod."},{"key":"10.1016\/j.jdent.2026.106942_bib0033","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.adaj.2018.06.004","article-title":"Variation in composite degree of conversion and microflexural strength for different curing lights and surface locations","volume":"149","author":"Eshmawi","year":"2018","journal-title":"J. Am. Dent. Assoc."},{"key":"10.1016\/j.jdent.2026.106942_bib0034","doi-asserted-by":"crossref","first-page":"275","DOI":"10.2334\/josnusd.19-0157","article-title":"Polymerization shrinkage kinetics and degree of conversion of resin composites","volume":"62","author":"Xu","year":"2020","journal-title":"J. Oral Sci."},{"key":"10.1016\/j.jdent.2026.106942_bib0036","doi-asserted-by":"crossref","first-page":"679","DOI":"10.4012\/dmj.28.679","article-title":"Effect of filler content of flowable composites on resin-cavity interface","volume":"28","author":"Ikeda","year":"2009","journal-title":". Dent. Mater. J."},{"key":"10.1016\/j.jdent.2026.106942_bib0037","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.actbio.2016.04.034","article-title":"Effect of nanolayering of calcium salts of phosphoric acid ester monomers on the durability of resin-dentin bonds","volume":"38","author":"Tian","year":"2016","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jdent.2026.106942_bib0038","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1177\/154405910408300604","article-title":"Comparative study on adhesive performance of functional monomers","volume":"83","author":"Yoshida","year":"2004","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jdent.2026.106942_bib0039","doi-asserted-by":"crossref","first-page":"29","DOI":"10.4103\/2278-0203.132892","article-title":"A Comparison of shear bond strength of orthodontic brackets bonded with four different orthodontic adhesives","volume":"3","author":"Sharma","year":"2014","journal-title":"J. Orthod. Sci."},{"key":"10.1016\/j.jdent.2026.106942_bib0010","doi-asserted-by":"crossref","first-page":"6770","DOI":"10.3390\/ma16206770","article-title":"Novel remineralizing and antibiofilm low-shrinkage-stress nanocomposites to inhibit salivary biofilms and protect tooth structures","volume":"16","author":"Alhussein","year":"2023","journal-title":"Materials"},{"key":"10.1016\/j.jdent.2026.106942_bib0040","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.jdent.2013.02.001","article-title":"Effects of dual antibacterial agents mdpb and nano-silver in primer on microcosm biofilm, cytotoxicity and dentine bond properties","volume":"41","author":"Zhang","year":"2013","journal-title":"J. Dent."},{"key":"10.1016\/j.jdent.2026.106942_bib0041","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.dental.2012.01.005","article-title":"Antibacterial amorphous calcium phosphate nanocomposites with a quaternary ammonium dimethacrylate and silver nanoparticles","volume":"28","author":"Cheng","year":"2012","journal-title":"Dent. Mater."},{"key":"10.1016\/j.jdent.2026.106942_bib0042","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/j.1834-7819.2008.00064.x","article-title":"Dental caries: a dynamic disease process","volume":"53","author":"Featherstone","year":"2008","journal-title":"Aust. Dent. J."}],"container-title":["Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571226006123?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300571226006123?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:28:47Z","timestamp":1790774927000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300571226006123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":41,"alternative-id":["S0300571226006123"],"URL":"https:\/\/doi.org\/10.1016\/j.jdent.2026.106942","relation":{},"ISSN":["0300-5712"],"issn-type":[{"value":"0300-5712","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bioactive orthodontic adhesive for clear-aligner attachments: antibacterial activity, ion release, and bonding performance","name":"articletitle","label":"Article Title"},{"value":"Journal of Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdent.2026.106942","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106942"}}