{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T03:48:54Z","timestamp":1791776934621,"version":"4.3.4"},"reference-count":45,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dermatological Science"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.jdermsci.2008.08.003","type":"journal-article","created":{"date-parts":[[2008,9,14]],"date-time":"2008-09-14T09:56:13Z","timestamp":1221386173000},"page":"55-59","source":"Crossref","is-referenced-by-count":28,"title":["Increased vagal modulation in atopic dermatitis"],"prefix":"10.1016","volume":"53","author":[{"given":"Michael Karl","family":"Boettger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-J\u00fcrgen","family":"B\u00e4r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Dohrmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helge","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz","family":"Mertins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert Hironimus","family":"Brockmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus Willy","family":"Agelink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdermsci.2008.08.003_bib1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1749-6632.2003.tb03153.x","article-title":"Endocrine and immune responses to stress in chronic inflammatory skin disorders","volume":"992","author":"Buske-Kirschbaum","year":"2003","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib2","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/0022-3999(87)90016-X","article-title":"The relation of stress and family environment to atopic dermatitis symptoms in children","volume":"31","author":"Gil","year":"1987","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib3","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/0022-3999(93)90058-N","article-title":"Personality characteristics and serum IgE level in patients with atopic dermatitis","volume":"37","author":"Scheich","year":"1993","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib4","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1111\/j.1749-6632.1999.tb08697.x","article-title":"Depression modulates pruritus perception. A study of pruritus in psoriasis, atopic dermatitis and chronic idiopathic urticaria","volume":"885","author":"Gupta","year":"1999","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib5","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1111\/j.1365-2133.2005.06449.x","article-title":"Anxiety accelerates T-helper 2-tilted immune responses in patients with atopic dermatitis","volume":"152","author":"Hashizume","year":"2005","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib6","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1038\/sj.jid.5701171","article-title":"Neuroimmune communication in skin: far from peripheral","volume":"128","author":"Hendrix","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib7","doi-asserted-by":"crossref","first-page":"4245","DOI":"10.1210\/jc.2001-010872","article-title":"Altered responsiveness of the hypothalamus-pituitary-adrenal axis and the sympathetic adrenomedullary system to stress in patients with atopic dermatitis","volume":"87","author":"Buske-Kirschbaum","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib8","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0889-1591(02)00021-1","article-title":"Stress and the inflammatory response: a review of neurogenic inflammation","volume":"16","author":"Black","year":"2002","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib9","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/sj.jid.5701079","article-title":"Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice","volume":"128","author":"Pavlovic","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib10","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0165-5728(02)00168-6","article-title":"Stress-induced immunomodulation is altered in patients with atopic dermatitis","volume":"129","author":"Buske-Kirschbaum","year":"2002","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib11","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1172\/JCI30555","article-title":"Physiology and immunology of the cholinergic antiinflammatory pathway","volume":"117","author":"Tracey","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib12","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1038\/nature01321","article-title":"The inflammatory reflex","volume":"420","author":"Tracey","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib13","doi-asserted-by":"crossref","first-page":"98","DOI":"10.7205\/MILMED.172.1.98","article-title":"Heart rate variability in patients with allergic rhinitis","volume":"172","author":"Yokusoglu","year":"2007","journal-title":"Mil Med"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib14","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3109\/02770908509087111","article-title":"Beat-to-beat variation of the heart rate in children with allergic asthma","volume":"22","author":"Tokuyama","year":"1985","journal-title":"J Asthma"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib15","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S0006-3223(01)01347-6","article-title":"Diminished chaos of heart rate time series in patients with major depression","volume":"51","author":"Yeragani","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib16","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1399-5618.2007.00503.x","article-title":"Nonlinear broad band dynamics are less complex in major depression","volume":"10","author":"Boettger","year":"2008","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib17","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jad.2003.12.016","article-title":"The influence of major depression and its treatment on heart rate variability and pupillary light reflex parameters","volume":"82","author":"Bar","year":"2004","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib18","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/da.1019","article-title":"Heart rate and QT variability in children with anxiety disorders: a preliminary report","volume":"13","author":"Yeragani","year":"2001","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jpsychores.2005.10.011","article-title":"Increased pulse-wave velocity in patients with anxiety: implications for autonomic dysfunction","volume":"61","author":"Yeragani","year":"2006","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib20","doi-asserted-by":"crossref","first-page":"44","DOI":"10.2340\/00015555924447","article-title":"Diagnostic features of atopic dermatitis","volume":"92","author":"Hanifin","year":"1980","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib21","doi-asserted-by":"crossref","unstructured":"Task Force on Atopic Dermatitis. Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis. Dermatology 1993; 186:23\u201331.","DOI":"10.1159\/000247298"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib22","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.2044-8260.1977.tb00241.x","article-title":"Factorial invariance across gender for the primary symptom dimensions of the SCL-90","volume":"16","author":"Derogatis","year":"1977","journal-title":"Br J Soc Clin Psychol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib23","unstructured":"Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 1996; 93:1043\u201365."},{"key":"10.1016\/j.jdermsci.2008.08.003_bib24","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF02322053","article-title":"Standardized tests of heart rate variability: normal ranges obtained from 309 healthy humans, and effects of age, gender, and heart rate","volume":"11","author":"Agelink","year":"2001","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib25","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1464-5491.1992.tb01754.x","article-title":"Assessment of cardiovascular autonomic function: age-related normal ranges and reproducibility of spectral analysis, vector analysis, and standard tests of heart rate variation and blood pressure responses","volume":"9","author":"Ziegler","year":"1992","journal-title":"Diabet Med"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib26","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1109\/TBME.1986.325789","article-title":"An efficient algorithm for spectral analysis of heart rate variability","volume":"33","author":"Berger","year":"1986","journal-title":"IEEE Trans Biomed Eng"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib27","first-page":"H713","article-title":"Heart rate and muscle sympathetic nerve variability during reflex changes of autonomic activity","volume":"258","author":"Saul","year":"1990","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib28","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1126\/science.6166045","article-title":"Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control","volume":"213","author":"Akselrod","year":"1981","journal-title":"Science"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib29","first-page":"H151","article-title":"Assessment of autonomic function in humans by heart rate spectral analysis","volume":"248","author":"Pomeranz","year":"1985","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib30","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1161\/01.CIR.85.6.2073","article-title":"Heart rate variability during the acute phase of myocardial infarction","volume":"85","author":"Casolo","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib31","doi-asserted-by":"crossref","first-page":"855","DOI":"10.2307\/2530931","article-title":"An improved method for measuring heart-rate variability: assessment of cardiac autonomic function","volume":"40","author":"Weinberg","year":"1984","journal-title":"Biometrics"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib32","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/BF02291234","article-title":"Autonomic cardiac abnormalities in alcohol-dependent patients admitted to a psychiatric department","volume":"6","author":"Rechlin","year":"1996","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib33","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.clinph.2005.09.027","article-title":"Assessment of cardiovascular autonomic function","volume":"117","author":"Freeman","year":"2006","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib34","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/S0002-9149(99)80680-8","article-title":"Decreased heart rate variability in men with phobic anxiety (data from the Normative Aging Study)","volume":"75","author":"Kawachi","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib35","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1024\/0040-5930.60.11.673","article-title":"Stress, depression and cardiac arrhythmias","volume":"60","author":"Brunckhorst","year":"2003","journal-title":"Ther Umsch"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib36","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1067\/mhj.2000.109981","article-title":"Heart rate variability in depressive and anxiety disorders","volume":"140","author":"Gorman","year":"2000","journal-title":"Am Heart J"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib37","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/nature01339","article-title":"Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation","volume":"421","author":"Wang","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib38","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/BF01983125","article-title":"Immunological modulation of cholinergic histamine release in isolated rat mast cells","volume":"16","author":"Masini","year":"1985","journal-title":"Agents Actions"},{"issue":"Pt 1","key":"10.1016\/j.jdermsci.2008.08.003_bib39","first-page":"40","article-title":"Anti-allergic effect of beta-2 agonists and cholinoceptor antagonists in vitro","volume":"128","author":"Morr","year":"1983","journal-title":"Eur J Respir Dis Suppl"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib40","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.clinph.2004.11.007","article-title":"Lateralization of pupillary light reflex parameters","volume":"116","author":"Bar","year":"2005","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib41","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jad.2007.12.236","article-title":"Gastric dysmotility in patients with major depression","volume":"110","author":"Ruhland","year":"2008","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib42","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1111\/j.1468-1331.2008.02173.x","article-title":"Cardiovagal modulation upon postural change is altered in Huntington's disease","volume":"15","author":"B\u00e4r","year":"2008","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib43","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.psychres.2007.04.021","article-title":"Relationship between cardiovagal modulation and psychotic state in patients with paranoid schizophrenia","volume":"157","author":"Bar","year":"2008","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib44","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.drugalcdep.2006.03.014","article-title":"Reduced baroreflex sensitivity in acute alcohol withdrawal syndrome and in abstained alcoholics","volume":"85","author":"Bar","year":"2006","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.jdermsci.2008.08.003_bib45","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1016\/j.clinph.2007.06.012","article-title":"Non-linear complexity measures of heart rate variability in acute schizophrenia","volume":"118","author":"Bar","year":"2007","journal-title":"Clin Neurophysiol"}],"container-title":["Journal of Dermatological Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181108002405?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181108002405?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T23:23:03Z","timestamp":1684538583000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923181108002405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0923181108002405"],"URL":"https:\/\/doi.org\/10.1016\/j.jdermsci.2008.08.003","relation":{},"ISSN":["0923-1811"],"issn-type":[{"value":"0923-1811","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}