{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T05:12:12Z","timestamp":1760332332766,"version":"build-2065373602"},"reference-count":26,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jdsjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dermatological Science"],"published-print":{"date-parts":[[2009,8]]},"DOI":"10.1016\/j.jdermsci.2009.05.003","type":"journal-article","created":{"date-parts":[[2009,6,14]],"date-time":"2009-06-14T04:40:30Z","timestamp":1244954430000},"page":"108-115","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Subcellular localization of desmosomal components is different between desmoglein3 knockout mice and pemphigus vulgaris model mice"],"prefix":"10.1016","volume":"55","author":[{"given":"Hitoshi","family":"Saito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyuki","family":"Tsunoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Amagai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Ishiko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdermsci.2009.05.003_bib1","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0092-8674(91)90360-B","article-title":"Auto antibodies against a novel epithelial adhering in pemphigus vulgaris, a disease of cell adhesion","volume":"67","author":"Amagai","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib2","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1172\/JCI115968","article-title":"Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic","volume":"90","author":"Amagai","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib3","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1083\/jcb.137.5.1091","article-title":"Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris","volume":"137","author":"Koch","year":"1997","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib4","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1172\/JCI8748","article-title":"Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigus","volume":"105","author":"Amagai","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1046\/j.0022-202x.2001.01643.x","article-title":"Immunologic and histopathologic characterization of active disease mouse model for pemphigus vulgaris","volume":"118","author":"Ohyama","year":"2002","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib6","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/s00403-002-0341-z","article-title":"Ultrastructural changes in mice actively producing antibodies to desmoglein 3 parallel those in patients with pemphigus vulgaris","volume":"294","author":"Shimizu","year":"2002","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib7","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1083\/jcb.153.4.823","article-title":"A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris","volume":"153","author":"Calderali","year":"2001","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib8","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1111\/j.0022-202X.2004.22426.x","article-title":"IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model","volume":"122","author":"Shimizu","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib9","doi-asserted-by":"crossref","first-page":"7623","DOI":"10.1074\/jbc.M512447200","article-title":"Desmoglein endocytosis and desmosome disassembly are coordinated responses to pemphigus autoantibodies","volume":"281","author":"Calkin","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib10","doi-asserted-by":"crossref","first-page":"4379","DOI":"10.4049\/jimmunol.157.10.4379","article-title":"Development of CD4-CD8- abTCR+NK1.1+T lymphocytes: thymic selection by self antigen","volume":"157","author":"Schulz","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib11","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1128\/MCB.24.1.154-163.2004","article-title":"Assessment of splice variant-specific functions of desmocollin 1 in the skin","volume":"24","author":"Cheng","year":"2004","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib12","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.4049\/jimmunol.170.4.2170","article-title":"Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3","volume":"170","author":"Tsunoda","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib13","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/BF00510078","article-title":"Demonstration of intra- and extracellular localization of bullous pemphigoid antigen using cryofixation and freeze substitution for postembedding immunoelectron microscopy","volume":"281","author":"Shimizu","year":"1989","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib14","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1177\/40.6.1375240","article-title":"The use of silver-enhanced 1-nm gold probes for light and electron microscopic localization of intra- and extracellular antigens in skin","volume":"40","author":"Shimizu","year":"1992","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib15","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1111\/j.0022-202X.2005.23706.x","article-title":"In vivo ultrastructural localization of the desmoglein 3 adhesive interface to the desmosome mid-line","volume":"124","author":"Shimizu","year":"2005","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib16","doi-asserted-by":"crossref","first-page":"8310","DOI":"10.1016\/S0021-9258(18)83184-2","article-title":"Desmoplakin I and desmoplakin II. Purification and characterization","volume":"264","author":"O\u2019Keefe","year":"1989","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib17","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1083\/jcb.116.5.1197","article-title":"The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells","volume":"116","author":"Stappenbeck","year":"1992","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib18","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1083\/jcb.141.5.1229","article-title":"Defining the interactions between intermediate filaments and desmosomes","volume":"141","author":"Smith","year":"1998","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib19","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1083\/jcb.139.3.773","article-title":"The amino-terminal domain of desmoplakin binds to plakoglobin clusters desmosomal cadherin-plakoglobin complexes","volume":"139","author":"Kowalczyk","year":"1997","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib20","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/35043032","article-title":"Are desmosomes more then tethers for intermediate filaments?","volume":"1","author":"Green","year":"2000","journal-title":"Nat Rev"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib21","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/sj.jidsp.5640197","article-title":"Transmembrane signaling for adhesive regulation of desmosomes and hemidesmosomes, and for cell-cell detachment induced by pemphigus IgG in cultured keratinocytes: involvement of protein kinase C","volume":"4","author":"Kitajima","year":"1999","journal-title":"J Invest Dermatol Symp Proc"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib22","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1523-1747.1999.00463.x","article-title":"Pemphigus vulgaris-IgG causes a rapid detection of desmoglein 3(Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells","volume":"112","author":"Aoyama","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib23","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1002\/(SICI)1521-4141(199907)29:07<2233::AID-IMMU2233>3.0.CO;2-4","article-title":"A pathogenic autoantibody, pemphigus vulgaris-IgG, induces phosphorylation of desmoglein 3, and its dissociation from plakoglobin in cultured keratinocytes","volume":"29","author":"Aoyama","year":"1999","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib24","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1034\/j.1600-0560.2001.028009460.x","article-title":"A possible role of catenin dyslocalization in pemphigus vulgaris pathogenesis","volume":"28","author":"Lo Muzio","year":"2001","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib25","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1080\/08916930600971885","article-title":"Pemphigus antibody induced phosphorylation of keratinocyte proteins","volume":"39","author":"Rubenstein","year":"2006","journal-title":"Autoimmunity (England)"},{"key":"10.1016\/j.jdermsci.2009.05.003_bib26","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.4049\/jimmunol.181.3.1825","article-title":"Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction","volume":"181","author":"Heupel","year":"2008","journal-title":"J Immunol"}],"container-title":["Journal of Dermatological Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181109001522?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181109001522?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T04:46:43Z","timestamp":1760330803000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923181109001522"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["S0923181109001522"],"URL":"https:\/\/doi.org\/10.1016\/j.jdermsci.2009.05.003","relation":{},"ISSN":["0923-1811"],"issn-type":[{"type":"print","value":"0923-1811"}],"subject":[],"published":{"date-parts":[[2009,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Subcellular localization of desmosomal components is different between desmoglein3 knockout mice and pemphigus vulgaris model mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Dermatological Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdermsci.2009.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}