{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T15:58:02Z","timestamp":1771862282874,"version":"3.50.1"},"reference-count":50,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jdsjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dermatological Science"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1016\/j.jdermsci.2011.07.007","type":"journal-article","created":{"date-parts":[[2011,8,30]],"date-time":"2011-08-30T13:51:42Z","timestamp":1314712302000},"page":"1-6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Erythrodermic cutaneous T-cell lymphoma: How to differentiate this rare disease from atopic dermatitis"],"prefix":"10.1016","volume":"64","author":[{"given":"Tomomitsu","family":"Miyagaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Sugaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdermsci.2011.07.007_bib0005","doi-asserted-by":"crossref","first-page":"3768","DOI":"10.1182\/blood-2004-09-3502","article-title":"WHO-EORTC classification for cutaneous lymphomas","volume":"105","author":"Willemze","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0010","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1182\/blood-2007-03-055749","volume":"110","author":"Olsen","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0015","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1001\/archderm.139.7.857","article-title":"Long-term outcome of 525 patients with mycosis fungoides and S\u00e9zary syndrome: clinical prognostic factors and risk for disease progression","volume":"139","author":"Kim","year":"2003","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0020","first-page":"1197","article-title":"Folliculotropic mycosis fungoides (stage IIA) progressing to S\u00e9zary syndrome: a case report","volume":"159","author":"Agar","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0025","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.clindermatol.2004.06.018","article-title":"Life-threatening erythroderma: diagnosing and treating the \u201cred man\u201d","volume":"23","author":"Rothe","year":"2005","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0030","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/1523-1747.ep12611877","article-title":"Aberrant cytokine production by S\u00e9zary syndrome patients: cytokine secretion pattern resembles murine Th2 cells","volume":"99","author":"Vowels","year":"1992","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0035","doi-asserted-by":"crossref","first-page":"515","DOI":"10.3109\/10428199809058359","article-title":"S\u00e9zary syndrome, T-helper 2 cytokines and accessory factor-1 (AF-1)","volume":"28","author":"Dummer","year":"1998","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0040","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1111\/1523-1747.ep12398454","article-title":"Th2 cytokine mRNA expression in skin in cutaneous T-cell lymphoma","volume":"103","author":"Vowels","year":"1994","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0045","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1111\/1523-1747.ep12330869","article-title":"Progression of mycosis fungoides is associated with increasing cutaneous expression of interleukin-10 mRNA","volume":"107","author":"Asadullah","year":"1996","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0050","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2340\/00015555-0789","article-title":"Pruritus in cutaneous T-cell lymphomas: frequent, often severe and difficult to treat","volume":"90","author":"Meyer","year":"2010","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0055","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.1200\/JCO.2006.10.2434","article-title":"Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma","volume":"25","author":"Olsen","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0060","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1046\/j.1365-2133.2003.05224.x","article-title":"The relevance of peripheral blood T-helper 1 and 2 cytokine pattern in the evaluation of patients with mycosis fungoides and S\u00e9zary syndrome","volume":"148","author":"Papadavid","year":"2003","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0065","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.coi.2010.10.013","article-title":"IL-17 and IL-22 in atopic allergic disease","volume":"22","author":"Souwer","year":"2010","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0070","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S0091-6749(99)70024-2","article-title":"Use of specific IgE in assessing the relevance of fungal and dust mite allergens to atopic dermatitis: a comparison with asthmatic and nonasthmatic control subjects","volume":"104","author":"Scalabrin","year":"1999","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0075","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.imbio.2007.03.001","article-title":"The pro- and anti-inflammatory properties of human antigen-presenting cells expressing the high affinity receptor for IgE (Fc epsilon RI)","volume":"212","author":"Bieber","year":"2007","journal-title":"Immunobiology"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0080","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1111\/j.1365-4632.2010.04228.x","article-title":"Atopy, IgE and eosinophilic cationic protein concentration, specific IgE positivity, eosinophil count in cutaneous T cell lymphoma","volume":"49","author":"Kural","year":"2010","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0085","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1001\/archderm.1991.01680090075007","article-title":"Prognostic clinicopathologic factors in cutaneous T-cell lymphoma","volume":"127","author":"Mart\u00ed","year":"1991","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0090","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1001\/archderm.1996.03890250052009","article-title":"Increased serum concentration of the soluble interleukin-2 receptor in cutaneous T-cell lymphoma. Clinical and prognostic implications","volume":"132","author":"Wasik","year":"1996","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0095","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/j.1346-8138.1990.tb01679.x","article-title":"Significance of elevated serum LDH (lactate dehydrogenase) activity in atopic dermatitis","volume":"17","author":"Mukai","year":"1990","journal-title":"J Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0100","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0923-1811(94)90081-7","article-title":"Serum soluble IL-2 receptor (sIL-2R) and eosinophil cationic protein (ECP) levels in atopic dermatitis","volume":"7","author":"Furue","year":"1994","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0105","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1067\/mjd.2003.132","article-title":"Thymus and activation-regulated chemokine (TARC) in mycosis fungoides: serum TARC levels reflect the disease activity of mycosis fungoides","volume":"48","author":"Kakinuma","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0110","doi-asserted-by":"crossref","first-page":"4048","DOI":"10.4049\/jimmunol.164.8.4048","article-title":"Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309","volume":"164","author":"Inngjerdingen","year":"2000","journal-title":"J Immunol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0115","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1046\/j.1523-1747.2002.19610.x","article-title":"Increased CCR4 expression in cutaneous T cell lymphoma","volume":"119","author":"Ferenczi","year":"2002","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0120","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/j.1365-2133.2004.06325.x","article-title":"Circulating clonal CLA(+) and CD4(+) T cells in S\u00e9zary syndrome express the skin-homing chemokine receptors CCR4 and CCR10 as well as the lymph node-homing chemokine receptor CCR7","volume":"152","author":"Sokolowska-Wojdylo","year":"2005","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0125","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1038\/sj.jid.5700246","article-title":"Elevated serum CTACK levels in CTCL","volume":"126","author":"Kagami","year":"2006","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0130","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1038\/jid.2010.128","article-title":"Eotaxins and CCR3 interaction regulates the Th2 environment of cutaneous T-cell lymphoma","volume":"130","author":"Miyagaki","year":"2010","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0135","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1067\/mai.2001.113237","article-title":"Thymus and activation-regulated chemokine in atopic dermatitis: serum thymus and activation-regulated chemokine level is closely related with disease activity","volume":"107","author":"Kakinuma","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0140","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1067\/mai.2003.114","article-title":"Increased serum cutaneous T cell-attracting chemokine (CCL27) levels in patients with atopic dermatitis and psoriasis vulgaris","volume":"111","author":"Kakinuma","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0145","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1007\/s004030100230","article-title":"Enhanced production of CC-chemokines (RANTES, MCP-1, MIP-1alpha, MIP-1beta, and eotaxin) in patients with atopic dermatitis","volume":"293","author":"Kaburagi","year":"2001","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0150","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1046\/j.1365-2249.2003.02273.x","article-title":"Significant elevation of serum levels of eotaxin-3\/CCL26, but not of eotaxin-2\/CCL24, in patients with atopic dermatitis: serum eotaxin-3\/CCL26 levels reflect the disease activity of atopic dermatitis","volume":"134","author":"Kagami","year":"2003","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0155","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/S0190-9622(96)90605-2","article-title":"Detection of circulating T cells with CD4+CD7\u2212 immunophenotype in patients with benign and malignant lymphoproliferative dermatoses","volume":"35","author":"Harmon","year":"1996","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0160","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1309\/U1Y6-J4AG-5M4M-7AYV","article-title":"Absence of CD26 expression is a useful marker for diagnosis of T-cell lymphoma in peripheral blood","volume":"115","author":"Jones","year":"2001","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0165","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/0190-9622(90)70080-2","article-title":"Leu-8\/CD7 antigen expression by CD3+ T cells: comparative analysis of skin and blood in mycosis fungoides\/S\u00e9zary syndrome relative to normal blood values","volume":"22","author":"Wood","year":"1990","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0170","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1046\/j.1523-1747.2002.18194.x","article-title":"T cell receptor-Vbeta analysis identifies a dominant CD60+ CD26\u2212 CD49d\u2212 T cell clone in the peripheral blood of S\u00e9zary syndrome patients","volume":"119","author":"Scala","year":"2002","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0175","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.3324\/haematol.2010.026260","article-title":"The role of 9-O-acetylated ganglioside D3 (CD60) and {alpha}4{beta}1 (CD49d) expression in predicting the survival of patients with S\u00e9zary syndrome","volume":"95","author":"Scala","year":"2010","journal-title":"Haematologica"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0180","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1111\/j.0022-202X.2004.22326.x","article-title":"CD158k\/KIR3DL2 is a new phenotypic marker of S\u00e9zary cells: relevance for the diagnosis and follow-up of S\u00e9zary syndrome","volume":"122","author":"Poszepczynska-Guign\u00e9","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0185","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1600-065X.1997.tb00943.x","article-title":"Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes","volume":"155","author":"Moretta","year":"1997","journal-title":"Immunol Rev"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0190","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/cyto.b.20395","article-title":"CD158k\/KIR3DL2 is a useful marker for identifying neoplastic T-cells in S\u00e9zary syndrome by flow cytometry","volume":"74","author":"Bahler","year":"2008","journal-title":"Cytometry B Clin Cytom"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0195","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1111\/j.1365-2133.2008.08739.x","article-title":"The diagnosis of S\u00e9zary syndrome on peripheral blood by flow cytometry requires the use of multiple markers","volume":"159","author":"Klemke","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0200","first-page":"7122","article-title":"Aberrant expression of T-plastin in S\u00e9zary cells","volume":"63","author":"Su","year":"2003","journal-title":"Cancer Res"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0205","doi-asserted-by":"crossref","first-page":"5578","DOI":"10.1158\/0008-5472.CAN-04-1253","article-title":"Aberrant expression of the tyrosine kinase receptor EphA4 and the transcription factor twist in S\u00e9zary syndrome identified by gene expression analysis","volume":"64","author":"van Doorn","year":"2004","journal-title":"Cancer Res"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0210","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1182\/blood-2002-07-2348","article-title":"CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking","volume":"101","author":"Soler","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0215","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1365-2230.2006.02261.x","article-title":"S\u00e9zary syndrome treated with narrowband ultraviolet B: time-course measurement of serum levels of CCL17\/CCL27","volume":"32","author":"Masui","year":"2007","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0220","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.jaad.2010.08.037","article-title":"S\u00e9zary syndrome: immunopathogenesis, literature review of therapeutic options, and recommendations for therapy by the United States Cutaneous Lymphoma Consortium (USCLC)","volume":"64","author":"Olsen","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0225","doi-asserted-by":"crossref","first-page":"4730","DOI":"10.1200\/JCO.2009.27.7665","article-title":"Survival outcomes and prognostic factors in mycosis fungoides\/S\u00e9zary syndrome: validation of the revised International Society for Cutaneous Lymphomas\/European Organisation for Research and Treatment of Cancer staging proposal","volume":"28","author":"Agar","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0230","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1365-4632.2009.03771.x","article-title":"Overall survival in erythrodermic cutaneous T-cell lymphoma: an analysis of prognostic factors in a cohort of patients with erythrodermic cutaneous T-cell lymphoma","volume":"48","author":"Vidulich","year":"2009","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0235","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1001\/archderm.1995.01690210033005","article-title":"Prognostic factors in erythrodermic mycosis fungoides and the S\u00e9zary syndrome","volume":"131","author":"Kim","year":"1995","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0240","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1023\/A:1008397323199","article-title":"Prognostic factors in S\u00e9zary syndrome: a multivariate analysis of clinical, haematological and immunological features","volume":"9","author":"Bernengo","year":"1998","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0245","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1111\/j.1365-2133.2003.05677.x","article-title":"Prognostic factors in S\u00e9zary syndrome: a study of 28 patients","volume":"149","author":"Foulc","year":"2003","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jdermsci.2011.07.007_bib0250","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1080\/1042819021000054652","article-title":"S\u00e9zary syndrome and related variants of classic cutaneous T-cell lymphoma. A descriptive and prognostic clinicopathologic study of 29 cases","volume":"44","author":"Marti","year":"2003","journal-title":"Leuk Lymphoma"}],"container-title":["Journal of Dermatological Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181111002301?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181111002301?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T04:47:23Z","timestamp":1760330843000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923181111002301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S0923181111002301"],"URL":"https:\/\/doi.org\/10.1016\/j.jdermsci.2011.07.007","relation":{},"ISSN":["0923-1811"],"issn-type":[{"value":"0923-1811","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Erythrodermic cutaneous T-cell lymphoma: How to differentiate this rare disease from atopic dermatitis","name":"articletitle","label":"Article Title"},{"value":"Journal of Dermatological Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdermsci.2011.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}