{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T08:39:07Z","timestamp":1778661547291,"version":"3.51.4"},"reference-count":10,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dermatological Science"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.jdermsci.2012.01.001","type":"journal-article","created":{"date-parts":[[2012,1,14]],"date-time":"2012-01-14T19:46:20Z","timestamp":1326570380000},"page":"220-222","source":"Crossref","is-referenced-by-count":5,"title":["Differential expression of T cell immunoglobulin- and mucin-domain-containing molecule-3 (TIM-3) according to activity of Beh\u00e7et's disease"],"prefix":"10.1016","volume":"65","author":[{"given":"Joong Sun","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Jin","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun-So","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdermsci.2012.01.001_bib0005","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/j.1365-2249.2005.02695.x","article-title":"Involvement of Th1 cells and heat shock protein 60 in the pathogenesis of intestinal Behcet's disease","volume":"139","author":"Imamura","year":"2005","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jdermsci.2012.01.001_bib0010","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1038\/nri1111","article-title":"The TIM gene family: emerging roles in immunity and disease","volume":"3","author":"Kuchroo","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jdermsci.2012.01.001_bib0015","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/415536a","article-title":"Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease","volume":"415","author":"Monney","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.jdermsci.2012.01.001_bib0020","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1189\/jlb.1006610","article-title":"Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17","volume":"81","author":"Nakae","year":"2007","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.jdermsci.2012.01.001_bib0025","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.clim.2010.07.012","article-title":"Increased Tim-3 expression on peripheral lymphocytes from patients with rheumatoid arthritis negatively correlates with disease activity","volume":"137","author":"Liu","year":"2010","journal-title":"Clin Immunol"},{"key":"10.1016\/j.jdermsci.2012.01.001_bib0030","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1038\/ni987","article-title":"Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance","volume":"4","author":"S\u00e1nchez-Fueyo","year":"2003","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jdermsci.2012.01.001_bib0035","doi-asserted-by":"crossref","first-page":"7169","DOI":"10.4049\/jimmunol.172.11.7169","article-title":"T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis","volume":"172","author":"Khademi","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.jdermsci.2012.01.001_bib0040","doi-asserted-by":"crossref","first-page":"4409","DOI":"10.4049\/jimmunol.180.7.4409","article-title":"Lack of TIM-3 immunoregulation in multiple sclerosis","volume":"180","author":"Yang","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.jdermsci.2012.01.001_bib0045","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1002\/eji.200939274","article-title":"TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines","volume":"39","author":"Hastings","year":"2009","journal-title":"Eur J Immunol"},{"issue":"April","key":"10.1016\/j.jdermsci.2012.01.001_bib0050","article-title":"CD4(+) CD25(+) regulatory T cells ameliorate Behcet's disease-like symptoms in a mouse model","author":"Shim","year":"2011","journal-title":"Cytotherapy"}],"container-title":["Journal of Dermatological Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181112000023?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181112000023?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T02:55:37Z","timestamp":1543287337000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923181112000023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S0923181112000023"],"URL":"https:\/\/doi.org\/10.1016\/j.jdermsci.2012.01.001","relation":{},"ISSN":["0923-1811"],"issn-type":[{"value":"0923-1811","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}