{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T17:40:19Z","timestamp":1791049219703,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jdsjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dermatological Science"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.jdermsci.2012.03.007","type":"journal-article","created":{"date-parts":[[2012,3,30]],"date-time":"2012-03-30T15:58:50Z","timestamp":1333123130000},"page":"233-237","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":98,"title":["Long TSLP transcript expression and release of TSLP induced by TLR ligands and cytokines in human keratinocytes"],"prefix":"10.1016","volume":"66","author":[{"given":"Yang","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiro","family":"Takai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ko","family":"Okumura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideoki","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdermsci.2012.03.007_bib0005","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2332\/allergolint.11-RAI-0395","article-title":"TSLP expression: cellular sources, triggers, and regulatory mechanisms","volume":"61","author":"Takai","year":"2012","journal-title":"Allergol Int"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0010","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2332\/allergolint.11-RAI-0394","article-title":"TSLP and immune homeostasis","volume":"61","author":"Hanabuchi","year":"2012","journal-title":"Allergol Int"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0015","doi-asserted-by":"crossref","first-page":"27","DOI":"10.2332\/allergolint.11-RAI-0374","article-title":"Mouse models of allergic diseases: TSLP and its functional roles","volume":"61","author":"Omori-Miyake","year":"2012","journal-title":"Allergol Int"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0020","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2332\/allergolint.11-RAI-0376","article-title":"Cellular and molecular mechanisms of TSLP function in human allergic disorders\u2014TSLP programs the \u201cTh2 code\u201d in dendritic cells","volume":"61","author":"Ito","year":"2012","journal-title":"Allergol Int"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0025","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1084\/jem.20051745","article-title":"Thymic stromal lymphopoietin: master switch for allergic inflammation","volume":"203","author":"Liu","year":"2006","journal-title":"J Exp Med"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0030","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/ni805","article-title":"Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP","volume":"3","author":"Soumelis","year":"2002","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0035","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.jaci.2007.01.003","article-title":"Thymic stromal lymphopoietin converts human epidermal Langerhans cells into antigen-presenting cells that induce proallergic T cells","volume":"119","author":"Ebner","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0040","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1084\/jem.20062211","article-title":"Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells","volume":"204","author":"Allakhverdi","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0045","doi-asserted-by":"crossref","first-page":"6720","DOI":"10.4049\/jimmunol.178.11.6720","article-title":"Cutting edge: direct action of thymic stromal lymphopoietin on activated human CD4+ T cells","volume":"178","author":"Rochman","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0050","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1165\/rcmb.2009-0168OC","article-title":"Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils: implications in allergic inflammation","volume":"43","author":"Wong","year":"2010","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0055","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jaci.2010.05.024","article-title":"Thymic stromal lymphopoietin-activated invariant natural killer T cells trigger an innate allergic immune response in atopic dermatitis","volume":"126","author":"Wu","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0060","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.it.2007.04.007","article-title":"The epithelium takes centre stage in asthma and atopic dermatitis","volume":"28","author":"Holgate","year":"2007","journal-title":"Trends Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0065","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/ni.1852","article-title":"Sensing the outside world: TSLP regulates barrier immunity","volume":"11","author":"Ziegler","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0070","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2332\/allergolint.10-RAI-0273","article-title":"Barrier dysfunction caused by environmental proteases in the pathogenesis of allergic diseases","volume":"60","author":"Takai","year":"2011","journal-title":"Allergol Int"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0075","doi-asserted-by":"crossref","first-page":"95","DOI":"10.2332\/allergolint.09-RAI-0162","article-title":"Alarming dendritic cells for allergic sensitization","volume":"59","author":"Willart","year":"2010","journal-title":"Allergol Int"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0080","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1165\/rcmb.2008-0041OC","article-title":"Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells","volume":"40","author":"Harada","year":"2009","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0085","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1165\/rcmb.2009-0418OC","article-title":"Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma","volume":"44","author":"Harada","year":"2011","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0090","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1038\/ng.887","article-title":"Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population","volume":"43","author":"Hirota","year":"2011","journal-title":"Nat Genet"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0095","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jaci.2008.10.008","article-title":"Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA","volume":"123","author":"Kinoshita","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0100","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1038\/jid.2011.185","article-title":"Extracellular double-stranded RNA induces TSLP via an endosomal acidification- and NF-\u03ba B-dependent pathway in human keratinocytes","volume":"131","author":"Vu","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0105","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.jaci.2010.09.002","article-title":"Staphylococcus aureus membrane and diacylated lipopeptide induce thymic stromal lymphopoietin in keratinocytes via the Toll-like receptor 2-Toll-like receptor 6 pathway","volume":"126","author":"Vu","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0110","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000318679","article-title":"Flagellin induces the expression of thymic stromal lymphopoietin in human keratinocytes via toll-like receptor 5","volume":"155","author":"Le","year":"2011","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0115","doi-asserted-by":"crossref","first-page":"3373","DOI":"10.4049\/jimmunol.178.6.3373","article-title":"Cutting edge: proinflammatory and Th2 cytokines synergize to induce thymic stromal lymphopoietin production by human skin keratinocytes","volume":"178","author":"Bogiatzi","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0120","doi-asserted-by":"crossref","first-page":"11736","DOI":"10.1073\/pnas.0604575103","article-title":"Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis","volume":"103","author":"Li","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0125","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1111\/j.1398-9995.2009.02032.x","article-title":"Inhibition of double-stranded RNA-induced TSLP in human keratinocytes by glucocorticoids","volume":"64","author":"Le","year":"2009","journal-title":"Allergy"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0130","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1159\/000301576","article-title":"Glucocorticoids inhibit double-stranded RNA-induced thymic stromal lymphopoietin release from keratinocytes in atopic cytokine milieu more effectively than tacrolimus","volume":"153","author":"Le","year":"2010","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0135","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1038\/jid.2011.124","article-title":"Infliximab infusions for Netherton syndrome: sustained clinical improvement correlates with a reduction of thymic stromal lymphopoietin levels in the skin","volume":"131","author":"Fontao","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0140","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1038\/jid.2008.295","article-title":"Transgenic expression of interleukin-13 in the skin induces a pruritic dermatitis and skin remodeling","volume":"129","author":"Zheng","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0145","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.jaci.2009.07.029","article-title":"Reply","volume":"124","author":"Takai","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jdermsci.2012.03.007_bib0150","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.cell.2011.03.027","article-title":"Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor","volume":"145","author":"Surjit","year":"2011","journal-title":"Cell"}],"container-title":["Journal of Dermatological Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181112001065?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181112001065?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T04:47:39Z","timestamp":1760330859000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923181112001065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0923181112001065"],"URL":"https:\/\/doi.org\/10.1016\/j.jdermsci.2012.03.007","relation":{},"ISSN":["0923-1811"],"issn-type":[{"value":"0923-1811","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long TSLP transcript expression and release of TSLP induced by TLR ligands and cytokines in human keratinocytes","name":"articletitle","label":"Article Title"},{"value":"Journal of Dermatological Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdermsci.2012.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}