{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T14:09:37Z","timestamp":1794492577062,"version":"4.9.1"},"reference-count":50,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jdsjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dermatological Science"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.jdermsci.2021.01.007","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T18:32:31Z","timestamp":1611426751000},"page":"156-163","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":71,"title":["Telogen Effluvium \u2013 a review of the science and current obstacles"],"prefix":"10.1016","volume":"101","author":[{"given":"Ginny Oong","family":"Chien Yin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce Lee","family":"Siong-See","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne C.E.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.jdermsci.2021.01.007_bib0005","first-page":"WC01","article-title":"A Hospital-based Study to Determine Causes of Diffuse Hair Loss in Women","volume":"9","author":"Malkud","year":"2015","journal-title":"J Clin Diagn Res."},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0010","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1001\/archderm.1961.01580080005001","article-title":"Pathologic dynamics of human hair loss. I. Telogen effluvium","volume":"83","author":"Kligman","year":"1961","journal-title":"Arch Dermatol."},{"issue":"9","key":"10.1016\/j.jdermsci.2021.01.007_bib0015","first-page":"WE01","article-title":"Telogen Effluvium: A Review","volume":"9","author":"Malkud","year":"2015","journal-title":"J Clin Diagn Res."},{"issue":"March(1)","key":"10.1016\/j.jdermsci.2021.01.007_bib0020","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1159\/000455882","article-title":"Intermittent Chronic Telogen Effluvium","volume":"3","author":"Rebora","year":"2017","journal-title":"Skin Appendage Disorders."},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0025","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0733-8635(05)70398-3","article-title":"Chronic telogen effluvium","volume":"14","author":"Whiting","year":"1996","journal-title":"Dermatol Clin."},{"issue":"October","key":"10.1016\/j.jdermsci.2021.01.007_bib0030","doi-asserted-by":"crossref","first-page":"745","DOI":"10.2147\/CCID.S227232","article-title":"Vitamin D Receptor Gene Polymorphism In Chronic Telogen Effluvium; A Case-Control Study","volume":"12","author":"Seleit","year":"2019","journal-title":"Clinical, Cosmetic and Investigational Dermatology"},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0035","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1001\/archderm.1993.01680240096017","article-title":"Telogen effluvium. New concepts and review","volume":"129","author":"Headington","year":"1993","journal-title":"Arch Dermatol"},{"issue":"1-2","key":"10.1016\/j.jdermsci.2021.01.007_bib0040","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1159\/000446118","article-title":"Proposing a Simpler Classification of Telogen Effluvium","volume":"2","author":"Rebora","year":"2016","journal-title":"Skin Appendage Disord."},{"issue":"2","key":"10.1016\/j.jdermsci.2021.01.007_bib0045","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1159\/000051723","article-title":"Teloptosis, a Turning Point in Hair Shedding Biorhythms","volume":"203","author":"Pi\u00e9rard-Franchimont","year":"2001","journal-title":"Dermatology"},{"issue":"2","key":"10.1016\/j.jdermsci.2021.01.007_bib0050","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jdermsci.2017.01.003","article-title":"Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction","volume":"86","author":"Huang","year":"2017","journal-title":"J Dermatol Sci."},{"issue":"12","key":"10.1016\/j.jdermsci.2021.01.007_bib0055","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1038\/jid.2011.227","article-title":"Modulation in Proteolytic Activity Is Identified as a Hallmark of Exogen by Transcriptional Profiling of Hair Follicles","volume":"131","author":"Higgins","year":"2011","journal-title":"Journal of Investigative Dermatology"},{"issue":"3 Pt 1","key":"10.1016\/j.jdermsci.2021.01.007_bib0060","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0190-9622(89)80231-2","article-title":"Telogen effluvium and minoxidil","volume":"21","author":"Bardelli","year":"1989","journal-title":"J Am Acad Dermatol."},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0065","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1111\/j.1468-3083.2010.03589.x","article-title":"Thyroid peroxidase antibodies in patients with telogen effluvium","volume":"24","author":"Baldari","year":"2010","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"6","key":"10.1016\/j.jdermsci.2021.01.007_bib0070","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1038\/sj.jid.5700704","article-title":"Substance P as an Immunomodulatory Neuropeptide in a Mouse Model for Autoimmune Hair Loss (Alopecia Areata)","volume":"127","author":"Siebenhaar","year":"2007","journal-title":"Journal of Investigative Dermatology"},{"issue":"3","key":"10.1016\/j.jdermsci.2021.01.007_bib0075","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4103\/ijt.ijt_23_19","article-title":"Expert consensus on the management of telogen effluvium in India","volume":"11","author":"Mysore","year":"2019","journal-title":"International Journal of Trichology"},{"issue":"6","key":"10.1016\/j.jdermsci.2021.01.007_bib0080","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/jid.1960.127","volume":"35","author":"Lynfield","year":"1960","journal-title":"Journal Of Investigative Dermatology"},{"issue":"2","key":"10.1016\/j.jdermsci.2021.01.007_bib0085","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.1365-2133.2007.08339.x","article-title":"Proteoglycan expression patterns in human hair follicle","volume":"158","author":"Malgouries","year":"2008","journal-title":"Br J Dermatol."},{"issue":"3","key":"10.1016\/j.jdermsci.2021.01.007_bib0090","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1111\/jdv.12914","article-title":"Postpartum telogen effluvium","volume":"30","author":"Rebora","year":"2016","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0095","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1007\/s00431-005-1707-y","article-title":"Transient neonatal hair loss: a common transient neonatal dermatosis","volume":"164","author":"Cutrone","year":"2005","journal-title":"Eur J Pediatr"},{"issue":"1","key":"10.1016\/j.jdermsci.2021.01.007_bib0100","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1097\/00003246-198801000-00020","article-title":"Postfebrile telogen effluvium in critically ill patients","volume":"16","author":"Bernstein","year":"1988","journal-title":"Critical Care Medicine"},{"issue":"1","key":"10.1016\/j.jdermsci.2021.01.007_bib0105","doi-asserted-by":"crossref","DOI":"10.23736\/S0392-0488.17.05643-7","article-title":"Postfebrile telogen effluvium: hair fall after Rickettsia conorii infection","volume":"154","author":"Rebora","year":"2019","journal-title":"Giornale Italiano Di Dermatologia E Venereologia"},{"issue":"3","key":"10.1016\/j.jdermsci.2021.01.007_bib0110","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.dsi.2017.03.005","article-title":"Dengue-associated telogen effluvium: A report of 14 patients","volume":"35","author":"Chu","year":"2017","journal-title":"Dermatologica Sinica"},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0115","doi-asserted-by":"crossref","DOI":"10.1111\/dth.13923","article-title":"Evaluation of the effects of COVID \u201019 pandemic on hair diseases through a web\u2010based questionnaire","author":"Turkmen","year":"2020","journal-title":"Dermatologic Therapy."},{"issue":"1","key":"10.1016\/j.jdermsci.2021.01.007_bib0120","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.clindermatol.2011.11.011","article-title":"Eating disorders and the skin","volume":"31","author":"Strumia","year":"2013","journal-title":"Clin Dermatol."},{"issue":"2","key":"10.1016\/j.jdermsci.2021.01.007_bib0125","doi-asserted-by":"crossref","first-page":"214","DOI":"10.5021\/ad.2018.30.2.214","article-title":"Localized Telogen Effluvium Following Hair Transplantation","volume":"30","author":"Loh","year":"2018","journal-title":"Ann Dermatol."},{"issue":"September","key":"10.1016\/j.jdermsci.2021.01.007_bib0130","article-title":"Localized Telogen Effluvium of the Donor Area After Hair Transplant Surgery in 12 Patients","author":"G\u00f3mez-Zubiaur","year":"2020","journal-title":"Dermatologic Surgery"},{"issue":"1","key":"10.1016\/j.jdermsci.2021.01.007_bib0135","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1365-2133.2005.06608.x","article-title":"\u2019Atrophic telogen effluvium\u2019 from cytotoxic drugs and a randomized controlled trial to investigate the possible protective effect of pretreatment with a topical vitamin D analogue in humans","volume":"153","author":"Bleiker","year":"2005","journal-title":"Br J Dermatol."},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0140","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1046\/j.1365-2133.2000.03408.x","article-title":"Thyroid hormone receptor \u03b21 is expressed in the human hair follicle","volume":"142","author":"Billoni","year":"2000","journal-title":"Br J Dermatol"},{"issue":"1","key":"10.1016\/j.jdermsci.2021.01.007_bib0145","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s13555-018-0278-6","article-title":"The Role of Vitamins and Minerals in Hair Loss: A Review","volume":"9","author":"Almohanna","year":"2018","journal-title":"Dermatology and Therapy."},{"issue":"12","key":"10.1016\/j.jdermsci.2021.01.007_bib0150","doi-asserted-by":"crossref","first-page":"2754","DOI":"10.5455\/annalsmedres.2019.06.355","article-title":"Retrospective evaluation of laboratory data of patients with telogen effluvium","volume":"26","author":"Akyurek","year":"2019","journal-title":"Annals of Medical Research."},{"issue":"5","key":"10.1016\/j.jdermsci.2021.01.007_bib0155","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/s40257-018-0363-8","article-title":"Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus","volume":"19","author":"Udompanich","year":"2018","journal-title":"American Journal Of Clinical Dermatology"},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0160","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1097\/AJP.0b013e31825e4437","article-title":"Indications for peripheral and central sensitization in patients with chronic scalp pain (trichodynia)","volume":"29","author":"Defrin","year":"2013","journal-title":"Clin J Pain"},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0165","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1111\/j.1468-3083.2009.03201.x","article-title":"Trichodynia is a distinguishing symptom of telogen ef\ufb02uvium","volume":"23","author":"Baldari","year":"2009","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"11","key":"10.1016\/j.jdermsci.2021.01.007_bib0170","first-page":"1236","article-title":"Telogen Effluvium With Dysesthesia (TED) Has Lower B12 Levels and May Respond to B12 Supplementation","volume":"17","author":"Daly","year":"2018","journal-title":"J Drugs Dermatol."},{"issue":"7","key":"10.1016\/j.jdermsci.2021.01.007_bib0175","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1111\/j.1365-2230.2008.03165.x","article-title":"The role of psychological factors and serum zinc, folate and vitamin B12levels in the aetiology of trichodynia: a case-control study","volume":"34","author":"Durusoy","year":"2009","journal-title":"Clinical and Experimental Dermatology."},{"issue":"2","key":"10.1016\/j.jdermsci.2021.01.007_bib0180","first-page":"125","article-title":"Psychotrichology: psychosomatic aspects of hair diseases","volume":"11","author":"Harth","year":"2012","journal-title":"JDDG: Journal Der Deutschen Dermatologischen Gesellschaft"},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0185","series-title":"An Atlas of Hair Pathology with Clinical Correlations","author":"Sperling","year":"2012"},{"issue":"4","key":"10.1016\/j.jdermsci.2021.01.007_bib0190","doi-asserted-by":"crossref","first-page":"170","DOI":"10.4103\/0974-7753.130385","article-title":"Trichoscopy in alopecias: diagnosis simplified","volume":"5","author":"Jain","year":"2013","journal-title":"Int J Trichology."},{"issue":"2","key":"10.1016\/j.jdermsci.2021.01.007_bib0195","doi-asserted-by":"crossref","first-page":"108","DOI":"10.4103\/0974-7753.58553","article-title":"Hair evaluation methods: merits and demerits","volume":"1","author":"Dhurat","year":"2009","journal-title":"Int J Trichology."},{"issue":"6","key":"10.1016\/j.jdermsci.2021.01.007_bib0200","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/S0190-9622(96)90113-9","article-title":"Chronic telogen effluvium: increased scalp hair shedding in middle-aged women","volume":"35","author":"Whiting","year":"1996","journal-title":"J Am Acad Dermatol."},{"issue":"5","key":"10.1016\/j.jdermsci.2021.01.007_bib0205","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1046\/j.1365-2230.2002.01076.x","article-title":"Nutritional factors and hair loss","volume":"27","author":"Rushton","year":"2002","journal-title":"Clin Exp Dermatol."},{"issue":"1","key":"10.1016\/j.jdermsci.2021.01.007_bib0210","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1046\/j.0412-5463.2001.00110.x","article-title":"Causes of hair loss and the developments in hair rejuvenation","volume":"24","author":"Rushton","year":"2002","journal-title":"Int J Cosmet Sci."},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0215","doi-asserted-by":"crossref","first-page":"431","DOI":"10.2147\/CCID.S173082","article-title":"Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium","volume":"11","author":"Sant\u2019Anna Addor","year":"2018","journal-title":"Clin Cosmet Investig Dermatol."},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0220","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.12688\/f1000research.11775.1","article-title":"Treatment of chronic telogen effluvium with oral minoxidil: A retrospective study","volume":"6","author":"Perera","year":"2017","journal-title":"F1000research"},{"issue":"August (8)","key":"10.1016\/j.jdermsci.2021.01.007_bib0225","article-title":"Low-dose naltrexone: a novel adjunctive treatment in symptomatic alopecias?","volume":"25","author":"Tortelly","year":"2019","journal-title":"Dermatol Online J."},{"issue":"6","key":"10.1016\/j.jdermsci.2021.01.007_bib0230","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1111\/1346-8138.14901","article-title":"Diagnostic and therapeutic approach to scalp dysesthesia: A case series and published work review","volume":"46","author":"Kinoshita\u2010Ise","year":"2019","journal-title":"The Journal Of Dermatology"},{"issue":"11","key":"10.1016\/j.jdermsci.2021.01.007_bib0235","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1111\/j.1365-4632.2011.05158.x","article-title":"Women with scalp dysesthesia treated with pregabalin","volume":"52","author":"Sarifakioglu","year":"2013","journal-title":"International Journal Of Dermatology"},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0240","first-page":"1","article-title":"Oxidative stress and antioxidant strategies in dermatology","author":"Baek","year":"2016","journal-title":"Redox Report"},{"key":"10.1016\/j.jdermsci.2021.01.007_bib0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.abd.2020.01.005","article-title":"Ischemia-modified albumin as a possible marker of oxidative stress in patients with telogen effluvium","author":"Savci","year":"2020","journal-title":"Anais Brasileiros De Dermatologia"},{"issue":"1","key":"10.1016\/j.jdermsci.2021.01.007_bib0250","doi-asserted-by":"crossref","first-page":"20","DOI":"10.4103\/ijt.ijt_78_17","article-title":"Research on the balance of thiol-disulfide in blood serum in women with telogen effluvium","volume":"11","author":"Akbas","year":"2019","journal-title":"International Journal Of Trichology"}],"container-title":["Journal of Dermatological Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181121000086?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181121000086?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T04:51:07Z","timestamp":1760331067000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923181121000086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":50,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S0923181121000086"],"URL":"https:\/\/doi.org\/10.1016\/j.jdermsci.2021.01.007","relation":{},"ISSN":["0923-1811"],"issn-type":[{"value":"0923-1811","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Telogen Effluvium \u2013 a review of the science and current obstacles","name":"articletitle","label":"Article Title"},{"value":"Journal of Dermatological Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdermsci.2021.01.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier B.V. on behalf of Japanese Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}