{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T23:16:01Z","timestamp":1782256561755,"version":"3.54.5"},"reference-count":48,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["8171101368"],"award-info":[{"award-number":["8171101368"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173427"],"award-info":[{"award-number":["82173427"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jdsjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dermatological Science"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.jdermsci.2022.11.001","type":"journal-article","created":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T03:59:04Z","timestamp":1668052744000},"page":"39-47","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["DNA methylation markers in peripheral blood for psoriatic arthritis"],"prefix":"10.1016","volume":"108","author":[{"given":"Min","family":"Deng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuwen","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruifang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanshan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guishao","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoli","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianjin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdermsci.2022.11.001_bib1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1136\/ard.2004.032482","article-title":"Psoriatic arthritis: epidemiology, clinical features, course, and outcome","volume":"64","author":"Gladman","year":"2005","journal-title":"Ann. Rheum. Dis."},{"issue":"2","key":"10.1016\/j.jdermsci.2022.11.001_bib2","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1136\/annrheumdis-2018-214065","article-title":"Prevalence and incidence of psoriasis and psoriatic arthritis","volume":"78","author":"Sewerin","year":"2019","journal-title":"Ann. Rheum. Dis."},{"issue":"7","key":"10.1016\/j.jdermsci.2022.11.001_bib3","doi-asserted-by":"crossref","first-page":"441","DOI":"10.2165\/00128071-200304070-00001","article-title":"Prevalence of joint disease in patients with psoriasis \u2013 implications for therapy","volume":"4","author":"Zachariae","year":"2003","journal-title":"Am. J. Clin. Dermatol."},{"issue":"10","key":"10.1016\/j.jdermsci.2022.11.001_bib4","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1056\/NEJMra1505557","article-title":"Psoriatic","volume":"376","author":"Ritchlin","year":"2017","journal-title":"Arthritis, N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.jdermsci.2022.11.001_bib5","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0190-9622(99)70112-X","article-title":"Psoriasis causes as much disability as other major medical diseases","volume":"41","author":"Rapp","year":"1999","journal-title":"J. Am. Acad. Dermatol."},{"issue":"5","key":"10.1016\/j.jdermsci.2022.11.001_bib6","doi-asserted-by":"crossref","first-page":"887","DOI":"10.3899\/jrheum.130797","article-title":"Depression and anxiety in psoriatic disease: prevalence and associated factors","volume":"41","author":"McDonough","year":"2014","journal-title":"J. Rheumatol."},{"issue":"8","key":"10.1016\/j.jdermsci.2022.11.001_bib7","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1136\/annrheumdis-2012-201308","article-title":"Differential human leucocyte allele association between psoriasis and psoriatic arthritis: a family-based association study","volume":"71","author":"Eder","year":"2012","journal-title":"Ann. Rheum. Dis."},{"issue":"10","key":"10.1016\/j.jdermsci.2022.11.001_bib8","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/j.humimm.2013.07.014","article-title":"Human leukocyte antigen alleles and susceptibility to psoriatic arthritis","volume":"74","author":"Chandran","year":"2013","journal-title":"Hum. Immunol."},{"issue":"4","key":"10.1016\/j.jdermsci.2022.11.001_bib9","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1002\/art.33415","article-title":"HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype","volume":"64","author":"Winchester","year":"2012","journal-title":"Arthritis Rheumatol."},{"issue":"9","key":"10.1016\/j.jdermsci.2022.11.001_bib10","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1136\/ard.2010.147421","article-title":"IL13 gene polymorphism is a marker for psoriatic arthritis among psoriasis patients","volume":"70","author":"Eder","year":"2011","journal-title":"Ann. Rheum. Dis."},{"issue":"6","key":"10.1016\/j.jdermsci.2022.11.001_bib11","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1111\/jdv.16203","article-title":"Circulating microRNAs in extracellular vesicles as potential biomarkers for psoriatic arthritis in patients with psoriasis","volume":"34","author":"Pasquali","year":"2020","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"issue":"7","key":"10.1016\/j.jdermsci.2022.11.001_bib12","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1093\/rheumatology\/keq105","article-title":"Soluble biomarkers differentiate patients with psoriatic arthritis from those with psoriasis without arthritis","volume":"49","author":"Chandran","year":"2010","journal-title":"Rheumatology"},{"issue":"12","key":"10.1016\/j.jdermsci.2022.11.001_bib13","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1002\/art.39800","article-title":"CXCL10 is a possible biomarker for the development of psoriatic arthritis among patients with psoriasis","volume":"68","author":"Abji","year":"2016","journal-title":"Arthritis Rheumatol."},{"issue":"10","key":"10.1016\/j.jdermsci.2022.11.001_bib14","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1136\/ard.2007.078428","article-title":"On the heritability of psoriatic arthritis. Disease concordance among monozygotic and dizygotic twins","volume":"67","author":"Pedersen","year":"2008","journal-title":"Ann. Rheum. Dis."},{"issue":"11","key":"10.1016\/j.jdermsci.2022.11.001_bib15","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1136\/annrheumdis-2015-208410","article-title":"IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus","volume":"75","author":"Zhao","year":"2016","journal-title":"Ann. Rheum. Dis."},{"issue":"7","key":"10.1016\/j.jdermsci.2022.11.001_bib16","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1200\/JCO.2016.68.2153","article-title":"CpG methylation signature predicts recurrence in early-stage hepatocellular carcinoma: results from a multicenter study","volume":"35","author":"Qiu","year":"2017","journal-title":"J. Clin. Oncol."},{"issue":"1","key":"10.1016\/j.jdermsci.2022.11.001_bib17","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jdermsci.2010.07.011","article-title":"Abnormal DNA methylation in skin lesions and PBMCs of patients with psoriasis vulgaris","volume":"60","author":"Zhang","year":"2010","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.jdermsci.2022.11.001_bib18","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jaut.2013.01.001","article-title":"Whole-genome DNA methylation in skin lesions from patients with psoriasis vulgaris","volume":"41","author":"Zhang","year":"2013","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.jdermsci.2022.11.001_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.746145","article-title":"DNA methylation patterns in CD8 T cells discern psoriasis from psoriatic arthritis and correlate with cutaneous disease activity","volume":"9","author":"Charras","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.jdermsci.2022.11.001_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.778677","article-title":"DNA methylation signature in monozygotic twins discordant for psoriatic disease","volume":"9","author":"Vecellio","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"8","key":"10.1016\/j.jdermsci.2022.11.001_bib21","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1002\/art.21972","article-title":"Classification criteria for psoriatic arthritis \u2013 development of new criteria from a large international study","volume":"54","author":"Taylor","year":"2006","journal-title":"Arthritis Rheumatol."},{"issue":"3","key":"10.1016\/j.jdermsci.2022.11.001_bib22","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780310302","article-title":"The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis","volume":"31","author":"Arnett","year":"1988","journal-title":"Arthritis Rheumatol."},{"issue":"5","key":"10.1016\/j.jdermsci.2022.11.001_bib23","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"clusterProfiler: an R package for comparing biological themes among gene clusters","volume":"16","author":"Yu","year":"2012","journal-title":"OMICS"},{"issue":"8","key":"10.1016\/j.jdermsci.2022.11.001_bib24","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.celrep.2016.10.059","article-title":"eFORGE: a tool for identifying cell type-specific signal in epigenomic data","volume":"17","author":"Breeze","year":"2016","journal-title":"Cell Rep."},{"issue":"2","key":"10.1016\/j.jdermsci.2022.11.001_bib25","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.ajhg.2014.07.002","article-title":"Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes","volume":"95","author":"Okada","year":"2014","journal-title":"Am. J. Hum. Genet."},{"issue":"7","key":"10.1016\/j.jdermsci.2022.11.001_bib26","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1093\/rheumatology\/keq105","article-title":"Soluble biomarkers differentiate patients with psoriatic arthritis from those with psoriasis without arthritis","volume":"49","author":"Chandran","year":"2010","journal-title":"Rheumatology"},{"issue":"2","key":"10.1016\/j.jdermsci.2022.11.001_bib27","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1111\/j.1365-2133.2008.08628.x","article-title":"Effects of etanercept on C-reactive protein levels in psoriasis and psoriatic arthritis","volume":"159","author":"Strober","year":"2008","journal-title":"Br. J. Dermatol."},{"issue":"1","key":"10.1016\/j.jdermsci.2022.11.001_bib28","first-page":"120","article-title":"Interleukin-6 and soluble interleukin-2 receptor alpha-markers of inflammation in patients with psoriatic arthritis?","volume":"27","author":"Alenius","year":"2009","journal-title":"Clin. Exp. Rheumatol."},{"issue":"12","key":"10.1016\/j.jdermsci.2022.11.001_bib29","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1002\/art.39800","article-title":"Brief report: CXCL10 is a possible biomarker for the development of psoriatic arthritis among patients with psoriasis","volume":"68","author":"Abji","year":"2016","journal-title":"Arthritis Rheumatol."},{"issue":"3","key":"10.1016\/j.jdermsci.2022.11.001_bib30","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1002\/acr.23298","article-title":"Differentiating psoriatic arthritis from psoriasis without psoriatic arthritis using novel serum biomarkers","volume":"70","author":"Cretu","year":"2018","journal-title":"Arthritis Care Res."},{"issue":"8","key":"10.1016\/j.jdermsci.2022.11.001_bib31","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/nrg1655","article-title":"DNA methylation and human disease","volume":"6","author":"Robertson","year":"2005","journal-title":"Nat. Rev. Genet."},{"issue":"12","key":"10.1016\/j.jdermsci.2022.11.001_bib32","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.1158\/0008-5472.CAN-15-3278","article-title":"DNA methylation in cancer and aging","volume":"76","author":"Klutstein","year":"2016","journal-title":"Cancer Res."},{"issue":"8","key":"10.1016\/j.jdermsci.2022.11.001_bib33","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1161\/CIRCULATIONAHA.118.039357","article-title":"Blood leukocyte DNA methylation predicts risk of future myocardial infarction and coronary heart disease a longitudinal study of 11 461 participants from population-based cohorts","volume":"140","author":"Agha","year":"2019","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.jdermsci.2022.11.001_bib34","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/pedi.12521","article-title":"DNA methylation and its role in the pathogenesis of diabetes","volume":"18","author":"Bansal","year":"2017","journal-title":"Pediatr. Diabetes"},{"issue":"5","key":"10.1016\/j.jdermsci.2022.11.001_bib35","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1177\/1759720X15598307","article-title":"Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implications","volume":"7","author":"Cribbs","year":"2015","journal-title":"Ther. Adv. Musculoskelet. Dis."},{"issue":"4","key":"10.1016\/j.jdermsci.2022.11.001_bib36","doi-asserted-by":"crossref","first-page":"505","DOI":"10.2217\/epi-2016-0096","article-title":"DNA methylation in systemic lupus erythematosus","volume":"9","author":"Hedrich","year":"2017","journal-title":"Epigenomics"},{"issue":"3","key":"10.1016\/j.jdermsci.2022.11.001_bib37","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/jid.2011.348","article-title":"A subset of methylated CpG sites differentiate psoriatic from normal skin","volume":"132","author":"Roberson","year":"2012","journal-title":"J. Invest. Dermatol."},{"issue":"4","key":"10.1016\/j.jdermsci.2022.11.001_bib38","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.jid.2015.12.029","article-title":"Epigenome-wide association analysis identified nine skin DNA methylation loci for psoriasis","volume":"136","author":"Zhou","year":"2016","journal-title":"J. Invest. Dermatol."},{"issue":"8","key":"10.1016\/j.jdermsci.2022.11.001_bib39","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1038\/jid.2015.128","article-title":"Correlation between reversal of DNA methylation and clinical symptoms in psoriatic epidermis following narrow-band UVB phototherapy","volume":"135","author":"Gu","year":"2015","journal-title":"J. Invest. Dermatol."},{"issue":"5","key":"10.1016\/j.jdermsci.2022.11.001_bib40","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.jid.2017.11.036","article-title":"Genome-wide DNA methylation profiling identifies differential methylation in uninvolved psoriatic epidermis","volume":"138","author":"Verma","year":"2018","journal-title":"J. Invest. Dermatol."},{"issue":"9","key":"10.1016\/j.jdermsci.2022.11.001_bib41","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1002\/art.42154","article-title":"Comparative genetic analysis of psoriatic arthritis and psoriasis for the discovery of genetic risk factors and risk prediction modeling","volume":"74","author":"Soomro","year":"2022","journal-title":"Arthritis Rheumatol."},{"issue":"5","key":"10.1016\/j.jdermsci.2022.11.001_bib42","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1002\/art.38376","article-title":"Interleukin-17+CD8+ T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression","volume":"66","author":"Menon","year":"2014","journal-title":"Arthritis Rheumatol."},{"issue":"2","key":"10.1016\/j.jdermsci.2022.11.001_bib43","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/BOR.0000000000000152","article-title":"Recognizing and managing comorbidities in psoriatic arthritis","volume":"27","author":"Ogdie","year":"2015","journal-title":"Curr. Opin. Rheuma"},{"key":"10.1016\/j.jdermsci.2022.11.001_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2020.108397","article-title":"Comorbidities associated with psoriatic arthritis: review and update","volume":"214","author":"Perez-Chada","year":"2020","journal-title":"Clin. Immunol."},{"issue":"10136","key":"10.1016\/j.jdermsci.2022.11.001_bib45","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1016\/S0140-6736(18)30830-4","article-title":"The pathogenesis of psoriatic arthritis","volume":"391","author":"Veale","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.jdermsci.2022.11.001_bib46","doi-asserted-by":"crossref","first-page":"h3978","DOI":"10.1136\/bmj.h3978","article-title":"Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies","volume":"351","author":"de Souza","year":"2015","journal-title":"BMJ"},{"issue":"6","key":"10.1016\/j.jdermsci.2022.11.001_bib47","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.5114\/aoms.2019.89451","article-title":"Abnormal serum fatty acid profile in psoriatic arthritis","volume":"15","author":"Mysliwiec","year":"2019","journal-title":"Arch. Med. Sci."},{"issue":"7","key":"10.1016\/j.jdermsci.2022.11.001_bib48","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1038\/jid.2010.103","article-title":"Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions","volume":"130","author":"Davidovici","year":"2010","journal-title":"J. Invest. Dermatol."}],"container-title":["Journal of Dermatological Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181122002468?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181122002468?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T04:52:46Z","timestamp":1760331166000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923181122002468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S0923181122002468"],"URL":"https:\/\/doi.org\/10.1016\/j.jdermsci.2022.11.001","relation":{},"ISSN":["0923-1811"],"issn-type":[{"value":"0923-1811","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DNA methylation markers in peripheral blood for psoriatic arthritis","name":"articletitle","label":"Article Title"},{"value":"Journal of Dermatological Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdermsci.2022.11.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Japanese Society for Investigative Dermatology. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}