{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:18:00Z","timestamp":1787170680464,"version":"build-2736575974"},"reference-count":10,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"am","delay-in-days":378,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Government of Japan Ministry of Education Culture Sports Science and Technology","doi-asserted-by":"publisher","award":["24K11456"],"award-info":[{"award-number":["24K11456"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Government of Japan Ministry of Education Culture Sports Science and Technology","doi-asserted-by":"publisher","award":["22K08436"],"award-info":[{"award-number":["22K08436"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Government of Japan Ministry of Education Culture Sports Science and Technology","doi-asserted-by":"publisher","award":["21K08305"],"award-info":[{"award-number":["21K08305"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100030844","name":"Lydia O&apos;Leary Memorial Pias Dermatological Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100030844","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008665","name":"Osaka Medical Research Foundation for Intractable Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jdsjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dermatological Science"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.jdermsci.2025.08.003","type":"journal-article","created":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T15:55:00Z","timestamp":1755618900000},"page":"39-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Granzyme K contributes to acute itch in psoriasis"],"prefix":"10.1016","volume":"120","author":[{"given":"Aoi","family":"Hiroyasu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beni","family":"Amatya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6283-0251","authenticated-orcid":false,"given":"Daisuke","family":"Tsuruta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Granville","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sho","family":"Hiroyasu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdermsci.2025.08.003_bib1","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1111\/jdv.15450","article-title":"Itch: an under-recognized problem in psoriasis","volume":"33","author":"Elewski","year":"2019","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.jdermsci.2025.08.003_bib2","doi-asserted-by":"crossref","DOI":"10.2340\/actadv.v103.4463","article-title":"Neuroimmune mediators of pruritus in hispanic scalp psoriatic itch","volume":"103","author":"Nattkemper","year":"2023","journal-title":"Acta Derm. Venereol."},{"key":"10.1016\/j.jdermsci.2025.08.003_bib3","first-page":"193","article-title":"Role of PAR-2 in neuroimmune communication and itch","author":"Kempkes","year":"2014","journal-title":"ITCH Mech. Treat."},{"issue":"13","key":"10.1016\/j.jdermsci.2025.08.003_bib4","first-page":"1","article-title":"Advances in the pathogenesis of psoriasis: from keratinocyte perspective","volume":"1","author":"Zhou","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jdermsci.2025.08.003_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1398120","article-title":"Granzyme k mediates IL-23-dependent inflammation and keratinocyte proliferation in psoriasis","volume":"15","author":"Richardson","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jdermsci.2025.08.003_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0270584","article-title":"Granzyme k initiates IL-6 and IL-8 release from epithelial cells by activating protease-activated receptor 2","author":"Kaiserman Id","year":"2022","journal-title":"PLoS One"},{"issue":"20","key":"10.1016\/j.jdermsci.2025.08.003_bib7","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/s41584-024-01109-5","article-title":"Granzyme serine proteases in inflammation and rheumatic diseases","volume":"6","author":"Aubert","year":"2024","journal-title":"Nat. Rev. Rheuma"},{"key":"10.1016\/j.jdermsci.2025.08.003_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2023.121786","article-title":"FSLLRY-NH2, a protease-activated receptor 2 (PAR2) antagonist, activates mas-related g protein-coupled receptor C11 (MrgprC11) to induce scratching behaviors in mice","volume":"325","author":"In Kim","year":"2023","journal-title":"Life. Sci."},{"key":"10.1016\/j.jdermsci.2025.08.003_bib9","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.jid.2021.06.019","article-title":"Mouse models of psoriasis: a comprehensive review","volume":"142","author":"Gangwar","year":"2022","journal-title":"J. Investig. Dermatol."},{"key":"10.1016\/j.jdermsci.2025.08.003_bib10","doi-asserted-by":"crossref","first-page":"ra45","DOI":"10.1126\/scisignal.2001925","article-title":"The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia","volume":"4","author":"Liu","year":"2011","journal-title":"Sci. Signal"}],"container-title":["Journal of Dermatological Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181125001392?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923181125001392?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T01:46:28Z","timestamp":1772847988000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923181125001392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S0923181125001392"],"URL":"https:\/\/doi.org\/10.1016\/j.jdermsci.2025.08.003","relation":{},"ISSN":["0923-1811"],"issn-type":[{"value":"0923-1811","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Granzyme K contributes to acute itch in psoriasis","name":"articletitle","label":"Article Title"},{"value":"Journal of Dermatological Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdermsci.2025.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Japanese Society for Investigative Dermatology. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}