{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T08:18:58Z","timestamp":1782548338115,"version":"3.54.5"},"reference-count":38,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jdcjournal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes and its Complications"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.jdiacomp.2016.01.021","type":"journal-article","created":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T12:01:18Z","timestamp":1454068878000},"page":"644-650","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Bone mineral density and intervertebral disc height in type 2 diabetes"],"prefix":"10.1016","volume":"30","author":[{"given":"Rachel","family":"Agius","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Galea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2372-7101","authenticated-orcid":false,"given":"Stephen","family":"Fava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0095","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1359\/jbmr.060609","article-title":"Intervertebral disc degeneration can predispose to anterior vertebral fractures in the thoracolumbar spine","volume":"21","author":"Adams","year":"2006","journal-title":"Journal of Bone and Mineral Research"},{"issue":"9","key":"10.1016\/j.jdiacomp.2016.01.021_bb0150","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1097\/00007632-199109000-00001","article-title":"1991 Volvo Award in clinical sciences. Smoking and lumbar intervertebral disc degeneration: an MRI study of identical twins","volume":"16","author":"Batti\u00e9","year":"1991","journal-title":"Spine (Phila Pa 1976)"},{"issue":"2","key":"10.1016\/j.jdiacomp.2016.01.021_bb0140","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3109\/03008207.2012.754886","article-title":"Polyol pathway mediates enhanced degradation of extracellular matrix via p38 MAPK activation in intervertebral disc of diabetic rats","volume":"54","author":"Cheng","year":"2013","journal-title":"Connective Tissue Research"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0065","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0140-6736(93)92555-8","article-title":"Bone density at various sites for prediction of hip fractures","volume":"341","author":"Cummings","year":"1993","journal-title":"Lancet"},{"issue":"14","key":"10.1016\/j.jdiacomp.2016.01.021_bb0165","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1056\/NEJMoa032804","article-title":"C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease","volume":"350","author":"Danesh","year":"2004","journal-title":"New England Journal of Medicine"},{"issue":"5","key":"10.1016\/j.jdiacomp.2016.01.021_bb0170","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1210\/jc.2007-2325","article-title":"Circulating levels of inflammatory markers predict change in bone mineral density and resorption in older adults: a longitudinal study","volume":"93","author":"Ding","year":"2008","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"issue":"5","key":"10.1016\/j.jdiacomp.2016.01.021_bb0125","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/jor.22807","article-title":"Alterations in intervertebral disc composition, matrix homeostasis and biomechanical behavior in the UCD-T2DM rat model of type 2 diabetes","volume":"33","author":"Fields","year":"2015","journal-title":"Journal of Orthopaedic Research"},{"issue":"4","key":"10.1016\/j.jdiacomp.2016.01.021_bb0175","first-page":"734","article-title":"Relationship between VKORC1 single nucleotide polymorphism 1173C>T, bone mineral density & carotid intima-media thickness","volume":"137","author":"Fodor","year":"2013","journal-title":"Indian Journal of Medical Research"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0130","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.ocl.2011.07.010","article-title":"Intervertebral disk nutrition: a review of factors influencing concentrations of nutrients and metabolites","volume":"42","author":"Grunhagen","year":"2011","journal-title":"The Orthopedic Clinics of North America"},{"issue":"5","key":"10.1016\/j.jdiacomp.2016.01.021_bb0035","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1002\/jbmr.2118","article-title":"Contemporary risk of hip fracture in type 1 and type 2 diabetes: a national registry study from Scotland","volume":"29","author":"Hothersall","year":"2014","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0040","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1093\/aje\/kwm106","article-title":"Systematic review of type 1 and type 2 diabetes mellitus and risk of fracture","volume":"166","author":"Janghorbani","year":"2007","journal-title":"American Journal of Epidemiology"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0075","doi-asserted-by":"crossref","first-page":"398397","DOI":"10.1155\/2014\/398397","article-title":"Relationship between serum total cholesterol level and serum biochemical bone turnover markers in healthy pre- and postmenopausal women","volume":"2014","author":"Jeong","year":"2014","journal-title":"BioMed Research International"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0115","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1002\/jor.22289","article-title":"Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: implications for diabetic intervertebral disc degeneration","volume":"31","author":"Jiang","year":"2013","journal-title":"Journal of Orthopaedic Research"},{"issue":"10","key":"10.1016\/j.jdiacomp.2016.01.021_bb0070","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1507\/endocrj.EJ13-0224","article-title":"Low bone mineral density is associated with dyslipidemia in South Korean men: the 2008\u20132010 Korean National Health and Nutrition Examination Survey","volume":"60","author":"Kim","year":"2013","journal-title":"Endocrine Journal"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0135","doi-asserted-by":"crossref","first-page":"543","DOI":"10.4184\/asj.2014.8.5.543","article-title":"High glucose accelerates autophagy in adult rat intervertebral disc cells","volume":"8","author":"Kong","year":"2014","journal-title":"Asian Spine Journal"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0010","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/dmrr.1197","article-title":"Diabetes and bone health: the relationship between diabetes and osteoporosis-associated fractures","volume":"27","author":"Kurra","year":"2011","journal-title":"Diabetes\/Metabolism Research and Reviews"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0090","doi-asserted-by":"crossref","first-page":"E1415","DOI":"10.1097\/BRS.0b013e31826f561e","article-title":"Morphological changes of lumbar vertebral bodies and intervertebral discs associated with decrease in bone mineral density of the spine: a cross-sectional study in elderly subjects","volume":"37","author":"Kwok","year":"2012","journal-title":"Spine (Phila Pa 1976)"},{"issue":"6","key":"10.1016\/j.jdiacomp.2016.01.021_bb0060","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-130-6-199903160-00002","article-title":"A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group","volume":"130","author":"Levey","year":"1999","journal-title":"Annals of Internal Medicine"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0155","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s11657-014-0175-2","article-title":"Body mass index is positively associated with bone mineral density in US older adults","volume":"9","author":"Lloyd","year":"2014","journal-title":"Archives of Osteoporosis"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0055","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1503\/cmaj.080486","article-title":"Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis","volume":"180","author":"Loke","year":"2009","journal-title":"CMAJ"},{"issue":"10","key":"10.1016\/j.jdiacomp.2016.01.021_bb0085","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1007\/s00586-011-1737-2","article-title":"Symptomatic disc herniation and serum lipid levels","volume":"20","author":"Longo","year":"2011","journal-title":"European Spine Journal"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0025","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s10654-012-9674-x","article-title":"Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies","volume":"27","author":"Ma","year":"2012","journal-title":"European Journal of Epidemiology"},{"issue":"4","key":"10.1016\/j.jdiacomp.2016.01.021_bb0050","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1080\/13697130701460640","article-title":"Low intervertebral disc height in postmenopausal women with osteoporotic vertebral fractures compared to hormone-treated and untreated postmenopausal women and premenopausal women without fractures","volume":"10","author":"Muscat Baron","year":"2007","journal-title":"Climacteric"},{"issue":"7","key":"10.1016\/j.jdiacomp.2016.01.021_bb0030","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.2337\/diacare.24.7.1192","article-title":"Type 1 and type 2 diabetes and incident hip fractures in postmenopausal women","volume":"24","author":"Nicodemus","year":"2001","journal-title":"Diabetes Care"},{"issue":"6","key":"10.1016\/j.jdiacomp.2016.01.021_bb0020","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.2337\/dc12-1188","article-title":"High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control. The Rotterdam Study","volume":"36","author":"Oei","year":"2013","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0180","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.rmed.2013.12.011","article-title":"Circulatory osteoprotegerin is related to osteoporosis of the hip in patients with COPD","volume":"108","author":"Pobeha","year":"2014","journal-title":"Respiratory Medicine"},{"issue":"7","key":"10.1016\/j.jdiacomp.2016.01.021_bb0100","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1097\/01.BRS.0000119401.23006.D2","article-title":"Intervertebral disc degeneration can lead to \u201cstress-shielding\u201d of the anterior vertebral body: a cause of osteoporotic vertebral fracture?","volume":"29","author":"Pollintine","year":"2004","journal-title":"Spine (Phila Pa 1976)"},{"issue":"5","key":"10.1016\/j.jdiacomp.2016.01.021_bb0015","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s00125-006-0154-2","article-title":"Bone mineral density and its determinants in diabetes: the Fremantle Diabetes Study","volume":"49","author":"Rakic","year":"2006","journal-title":"Diabetologia"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0105","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.jdiacomp.2015.05.007","article-title":"Fracture risk in patients with newly diagnosed type 2 diabetes: a retrospective database analysis in primary care","volume":"29","author":"Rathmann","year":"2015","journal-title":"Journal of Diabetes and its Complications"},{"issue":"3","key":"10.1016\/j.jdiacomp.2016.01.021_bb0185","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1210\/jc.2002-020775","article-title":"Increased osteoprotegerin serum levels in men with coronary artery disease","volume":"88","author":"Schoppet","year":"2003","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0005","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s11892-013-0376-x","article-title":"Diabetes mellitus and osteoporosis","volume":"13","author":"Sealand","year":"2013","journal-title":"Current Diabetes Reports"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0145","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/bmj.321.7258.405","article-title":"Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study","volume":"321","author":"Stratton","year":"2000","journal-title":"BMJ"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0120","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1002\/jor.22508","article-title":"Advanced glycation end products in degenerative nucleus pulposus with diabetes","volume":"32","author":"Tsai","year":"2014","journal-title":"Journal of Orthopaedic Research"},{"issue":"4","key":"10.1016\/j.jdiacomp.2016.01.021_bb0160","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.maturitas.2014.05.017","article-title":"Carotid intima-media thickness and calcification in relation to bone mineral density in postmenopausal women-the OSTPRE-BBA study","volume":"78","author":"V\u00e4rri","year":"2014","journal-title":"Maturitas"},{"issue":"4","key":"10.1016\/j.jdiacomp.2016.01.021_bb0045","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00198-006-0253-4","article-title":"Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes\u2014a meta-analysis","volume":"18","author":"Vestergaard","year":"2007","journal-title":"Osteoporosis International"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0080","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s12020-014-0292-0","article-title":"Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women","volume":"48","author":"Yamauchi","year":"2015","journal-title":"Endocrine"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0190","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.2337\/dc06-2606","article-title":"Thiazolidinedione treatment decreases bone mineral density in type 2 diabetic men","volume":"30","author":"Yaturu","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jdiacomp.2016.01.021_bb0110","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1210\/jc.2014-4177","article-title":"In postmenopausal female subjects with type 2 diabetes mellitus, vertebral fractures are independently associated with cortisol secretion and sensitivity","volume":"100","author":"Zhukouskaya","year":"2015","journal-title":"Journal of Clinical Endocrinology and Metabolism"}],"container-title":["Journal of Diabetes and its Complications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872716000490?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872716000490?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,15]],"date-time":"2018-09-15T17:57:26Z","timestamp":1537034246000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1056872716000490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["S1056872716000490"],"URL":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2016.01.021","relation":{},"ISSN":["1056-8727"],"issn-type":[{"value":"1056-8727","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bone mineral density and intervertebral disc height in type 2 diabetes","name":"articletitle","label":"Article Title"},{"value":"Journal of Diabetes and its Complications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2016.01.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}