{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T10:51:56Z","timestamp":1787827916201,"version":"build-2784847793"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jdcjournal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes and its Complications"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.jdiacomp.2016.06.025","type":"journal-article","created":{"date-parts":[[2016,7,2]],"date-time":"2016-07-02T04:59:37Z","timestamp":1467435577000},"page":"462-467","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Impaired cerebrovascular responsiveness and cognitive performance in adults with type 2 diabetes"],"prefix":"10.1016","volume":"31","author":[{"given":"Rhenan Scott","family":"Nealon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8410-1877","authenticated-orcid":false,"given":"Peter Ranald Charles","family":"Howe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyanne","family":"Jansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manohar","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel Heloise Xiwen","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdiacomp.2016.06.025_bb0005","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S1474-4422(08)70021-8","article-title":"Cognition and diabetes: A lifespan perspective","volume":"7","author":"Biessels","year":"2008","journal-title":"Lancet Neurology"},{"issue":"9","key":"10.1016\/j.jdiacomp.2016.06.025_bb0010","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.2337\/diab.45.9.1259","article-title":"Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats","volume":"45","author":"Biessels","year":"1996","journal-title":"Diabetes"},{"issue":"1","key":"10.1016\/j.jdiacomp.2016.06.025_bb0015","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S1474-4422(05)70284-2","article-title":"Risk of dementia in diabetes mellitus: A systematic review","volume":"5","author":"Biessels","year":"2006","journal-title":"Lancet Neurology"},{"key":"10.1016\/j.jdiacomp.2016.06.025_bb0020","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1161\/01.STR.17.5.913","article-title":"Transcranial Doppler measurement of middle cerebral artery blood flow velocity: A validation study","volume":"17","author":"Bishop","year":"1986","journal-title":"Stroke"},{"key":"10.1016\/j.jdiacomp.2016.06.025_bb0025","doi-asserted-by":"crossref","DOI":"10.1111\/j.1445-5994.2012.02758.x","article-title":"Diabetes as a risk factor for dementia and mild cognitive impairment: A meta-analysis of longitudinal studies","author":"Cheng","year":"2012","journal-title":"Internal Medicine Journal"},{"issue":"2","key":"10.1016\/j.jdiacomp.2016.06.025_bb0030","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1027\/0269-8803.22.2.81","article-title":"Patterns of cerebral blood flow and systemic hemodynamics during arithmetic processing","volume":"22","author":"Duschek","year":"2008","journal-title":"Journal of Psychophysiology"},{"key":"10.1016\/j.jdiacomp.2016.06.025_bb0035","first-page":"189","article-title":"\u201cMini Mental State\u201d: A practical method of grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"Journal of Psychiatry"},{"issue":"6","key":"10.1016\/j.jdiacomp.2016.06.025_bb0040","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s11906-013-0398-4","article-title":"Hypertension, brain damage and cognitive decline","volume":"15","author":"Gasecki","year":"2013","journal-title":"Current Hypertension Reports"},{"issue":"6","key":"10.1016\/j.jdiacomp.2016.06.025_bb0045","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1161\/CIRCULATIONAHA.106.621854","article-title":"Advanced glycation end products: Sparking the development of diabetic vascular injury","volume":"114","author":"Goldin","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jdiacomp.2016.06.025_bb0050","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/7208429","article-title":"The effect of diabetes medication on cognitive function: Evidence from the PATH through life study","author":"Herath","year":"2016","journal-title":"Biomed Research International"},{"issue":"1","key":"10.1016\/j.jdiacomp.2016.06.025_bb0055","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1159\/000339234","article-title":"Cerebrovascular function in aging and dementia: A systematic review of transcranial Doppler studies","volume":"2","author":"Keage","year":"2012","journal-title":"Dementia and Geriatric Cognitive Disorders Extra"},{"issue":"1\u20132","key":"10.1016\/j.jdiacomp.2016.06.025_bb0060","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0031-9384(01)00627-8","article-title":"Spatial memory deficit and emotional abnormality in OLETF rats","volume":"75","author":"Li","year":"2002","journal-title":"Physiology & Behavior"},{"issue":"5","key":"10.1016\/j.jdiacomp.2016.06.025_bb0065","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1253\/circj.CJ-11-0121","article-title":"Neurovascular coupling in cognitive impairment associated with diabetes mellitus","volume":"75","author":"Mogi","year":"2011","journal-title":"Circulation Journal"},{"issue":"5","key":"10.1016\/j.jdiacomp.2016.06.025_bb0070","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1097\/01.MLR.0000062554.74615.4C","article-title":"Interpretation of changes in health-related quality of life: The remarkable universality of half a standard deviation","volume":"41","author":"Norman","year":"2003","journal-title":"Medical Care"},{"key":"10.1016\/j.jdiacomp.2016.06.025_bb0075","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.2337\/dc06-0261","article-title":"Cerebral blood flow velocity and periventricular white matter hyperintensities in type 2 diabetes","volume":"29","author":"Novak","year":"2006","journal-title":"Diabetes Care"},{"issue":"7","key":"10.1016\/j.jdiacomp.2016.06.025_bb0080","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.2337\/dc06-0261","article-title":"Cerebral blood flow velocity and periventricular white matter hyperintensities in type 2 diabetes","volume":"29","author":"Novak","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jdiacomp.2016.06.025_bb0085","author":"Oxford Uo"},{"key":"10.1016\/j.jdiacomp.2016.06.025_bb0090","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.diabres.2007.08.029","article-title":"Cerebral arterial pulsatility and insulin resistance in type 2 diabetic patients","volume":"79","author":"Park","year":"2008","journal-title":"Diabetes Research and Clinical Practice"},{"issue":"12","key":"10.1016\/j.jdiacomp.2016.06.025_bb0095","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1161\/STROKEAHA.107.490755","article-title":"Noninvasive detection of diffuse intracranial disease","volume":"38","author":"Sharma","year":"2007","journal-title":"Stroke"},{"issue":"4","key":"10.1016\/j.jdiacomp.2016.06.025_bb0100","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1161\/01.STR.0000206439.62025.97","article-title":"Cerebrovascular reactivity and cognitive decline in patients with Alzheimer disease","volume":"37","author":"Silvestrini","year":"2006","journal-title":"Stroke"},{"issue":"4","key":"10.1016\/j.jdiacomp.2016.06.025_bb0105","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1023\/A:1026412811036","article-title":"Transcranial Doppler ultrasonography monitoring of cerebral hemodynamics during performance of cognitive tasks: A review","volume":"10","author":"Stroobant","year":"2000","journal-title":"Neuropsychology Review"},{"issue":"11","key":"10.1016\/j.jdiacomp.2016.06.025_bb0110","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/j.1468-1331.2004.00873.x","article-title":"Effect of cardiovascular disease on hemodynamic response to cognitive activation: A functional transcranial Doppler study","volume":"11","author":"Stroobant","year":"2004","journal-title":"European Journal of Neurology"},{"issue":"1\u20133","key":"10.1016\/j.jdiacomp.2016.06.025_bb0115","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ejphar.2004.02.055","article-title":"Hippocampal synaptic plasticity and glutamate receptor regulation: Influences of diabetes mellitus","volume":"490","author":"Trudeau","year":"2004","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.jdiacomp.2016.06.025_bb0120","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.2147\/CIA.S48926","article-title":"Type 2 diabetes as a risk factor for cognitive impairment: Current insights","volume":"9","author":"Umegaki","year":"2014","journal-title":"Clinical Interventions in Aging"},{"issue":"4","key":"10.1016\/j.jdiacomp.2016.06.025_bb0125","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1600-0404.2010.01462.x","article-title":"The prognostic value of pulsatility index, flow velocity, and their ratio, measured with TCD ultrasound, in patients with a recent TIA or ischemic stroke","volume":"124","author":"Wijnhoud","year":"2011","journal-title":"Acta Neurologica Scandinavica"},{"issue":"547","key":"10.1016\/j.jdiacomp.2016.06.025_bb0130","article-title":"Assessing premorbid cognitive ability in adults with type 2 diabetes mellitus\u2014A review with implications for future intervention studies","volume":"11","author":"Wong","year":"2014","journal-title":"Current Diabetes Reports"},{"issue":"6593","key":"10.1016\/j.jdiacomp.2016.06.025_bb0135","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/382685a0","article-title":"RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease","volume":"382","author":"Yan","year":"1996","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.jdiacomp.2016.06.025_bb0140","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.amjmed.2009.08.015","article-title":"Higher incidence of mild cognitive impairment in familial hypercholesterolemia","volume":"123","author":"Zambon","year":"2010","journal-title":"The American Journal of Medicine"},{"issue":"4","key":"10.1016\/j.jdiacomp.2016.06.025_bb0145","doi-asserted-by":"crossref","first-page":"185","DOI":"10.17305\/bjbms.2014.4.203","article-title":"Progress on diabetic cerebrovascular diseases","volume":"14","author":"Zhou","year":"2014","journal-title":"Bosnian Journal of Basic Medical Sciences"}],"container-title":["Journal of Diabetes and its Complications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872716302549?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872716302549?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T11:58:52Z","timestamp":1568116732000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1056872716302549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S1056872716302549"],"URL":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2016.06.025","relation":{},"ISSN":["1056-8727"],"issn-type":[{"value":"1056-8727","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impaired cerebrovascular responsiveness and cognitive performance in adults with type 2 diabetes","name":"articletitle","label":"Article Title"},{"value":"Journal of Diabetes and its Complications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2016.06.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}