{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T21:24:02Z","timestamp":1789593842524,"version":"build-2803163510"},"reference-count":21,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jdcjournal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes and its Complications"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.jdiacomp.2017.06.011","type":"journal-article","created":{"date-parts":[[2017,6,30]],"date-time":"2017-06-30T05:16:38Z","timestamp":1498799798000},"page":"1363-1369","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["Hydrogen sulfide improves diabetic wound healing in ob\/ob mice via attenuating inflammation"],"prefix":"10.1016","volume":"31","author":[{"given":"Huichen","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengxia","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiachao","family":"Chai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoli","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jicui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingbo","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiyan","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuantao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0005","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.ejvs.2006.03.006","article-title":"Early and five-year amputation and survival rate of diabetic patients with critical limb ischemia: Data of a cohort study of 564 patients","volume":"32","author":"Faglia","year":"2006","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0010","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3390\/molecules22010063","article-title":"Hydrogen sulfide in the adipose tissue-physiology, pathology and a target for pharmacotherapy","volume":"22","author":"Be\u0142towski","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0015","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ijcard.2014.01.068","article-title":"Targeting hydrogen sulfide as a promising therapeutic strategy for atherosclerosis","volume":"172","author":"Xu","year":"2014","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0020","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1097\/HJH.0b013e32833c20d5","article-title":"Systemic peripheral artery relaxation by KCNQ channel openers and hydrogen sulfide","volume":"28","author":"Schleifenbaum","year":"2010","journal-title":"J Hypertens"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0025","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1126\/science.1162667","article-title":"H2S as a physiologic vasorelaxant: Hypertension in mice with deletion of cystathionine gamma-lyase","volume":"322","author":"Yang","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0030","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jss.2009.05.010","article-title":"Hydrogen sulfide protects against ischemia-reperfusion injury in an in vitro model of cutaneous tissue transplantation","volume":"159","author":"Henderson","year":"2010","journal-title":"J Surg Res"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0035","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/978-3-319-18144-8_6","article-title":"H2S is a promoter of angiogenesis: Identification of H2S \u201creceptors\u201d and its molecular switches in vascular endothelial cells","volume":"230","author":"Tao","year":"2015","journal-title":"Handb Exp Pharmacol"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0040","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.2337\/db13-0483","article-title":"Hydrogen sulfide improves wound healing via restoration of endothelial progenitor cell functions and activation of angiopoietin-1 in type 2 diabetes","volume":"63","author":"Liu","year":"2014","journal-title":"Diabetes"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0045","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.phrs.2014.06.006","article-title":"Statins upregulate cystathionine \u03b3-lyase transcription and H2S generation via activating Akt signaling in macrophage","volume":"87","author":"Xu","year":"2014","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0050","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/1476-511X-13-155","article-title":"Involvement of CSE\/H2S in high glucose induced aberrant secretion of adipokines in 3T3-L1 adipocytes","volume":"13","author":"Pan","year":"2014","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0055","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1097\/FJC.0b013e31829875ef","article-title":"Hydrogen sulfide suppresses high glucose-induced expression of intercellular adhesion molecule-1 in endothelial cells","volume":"62","author":"Guan","year":"2013","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0060","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1097\/FJC.0b013e31823b4915","article-title":"Hydrogen sulfide protects against high-glucose-induced apoptosis in endothelial cells","volume":"59","author":"Guan","year":"2012","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0065","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1002\/jcp.24952","article-title":"TSH\/TSHR signaling suppresses fatty acid synthase (FASN) expression in adipocytes","volume":"230","author":"Chen","year":"2015","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0070","doi-asserted-by":"crossref","first-page":"E1365","DOI":"10.1152\/ajpendo.00604.2012","article-title":"Hydrogen sulfide deficiency and diabetic renal remodeling: Role of matrix metalloproteinase-9","volume":"304","author":"Kundu","year":"2013","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0075","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1177\/153857440503900401","article-title":"Angiogenesis, vasculogenesis, and induction of healing in chronic wounds","volume":"39","author":"Bauer","year":"2005","journal-title":"Vasc Endovascular Surg"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0080","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1053\/j.gastro.2009.04.012","article-title":"Endogenous and exogenous hydrogen sulphide promotes resolution of colitis in rats","volume":"137","author":"Wallace","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0085","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1089\/ars.2011.4351","article-title":"Hydrogen sulfide: An endogenous mediator of resolution of inflammation and injury","volume":"17","author":"Wallace","year":"2012","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0090","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1016\/j.cellsig.2013.07.010","article-title":"Dysregulation of cystathionine \u03b3-lyase (CSE)\/hydrogen sulfide pathway contributes to ox-LDL-induced inflammation in macrophage","volume":"25","author":"Wang","year":"2013","journal-title":"Cell Signal"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0100","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2147\/VHRM.S68415","article-title":"Matrix metalloproteinases in atherosclerosis: Role of nitric oxide, hydrogen sulfde, homocysteine, and polymorphisms","volume":"11","author":"Vacek","year":"2015","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0105","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.niox.2015.02.003","article-title":"MMP-9 and NMDA receptor-mediated mechanism of diabetic renovascular remodeling and kidney dysfunction: Hydrogen sulfide is a key modulator","volume":"46","author":"Kundu","year":"2015","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.jdiacomp.2017.06.011_bb0110","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1159\/000430266","article-title":"Exogenous hydrogen sulfide attenuates cardiac fibrosis through reactive oxygen species Signal pathways in experimental diabetes mellitus models","volume":"36","author":"Zheng","year":"2015","journal-title":"Cell Physiol Biochem"}],"container-title":["Journal of Diabetes and its Complications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872717304889?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872717304889?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T00:56:59Z","timestamp":1535677019000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1056872717304889"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["S1056872717304889"],"URL":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2017.06.011","relation":{},"ISSN":["1056-8727"],"issn-type":[{"value":"1056-8727","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hydrogen sulfide improves diabetic wound healing in ob\/ob mice via attenuating inflammation","name":"articletitle","label":"Article Title"},{"value":"Journal of Diabetes and its Complications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2017.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}