{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T01:45:27Z","timestamp":1792374327980,"version":"4.4.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000041","name":"American Diabetes Association","doi-asserted-by":"publisher","award":["NCT01234649"],"award-info":[{"award-number":["NCT01234649"]}],"id":[{"id":"10.13039\/100000041","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes and its Complications"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.jdiacomp.2020.107548","type":"journal-article","created":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T02:07:36Z","timestamp":1580522856000},"page":"107548","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Postpartum treatment with liraglutide in combination with metformin versus metformin monotherapy to improve metabolic status and reduce body weight in overweight\/obese women with recent gestational diabetes: A double-blind, randomized, placebo-controlled study"],"prefix":"10.1016","volume":"34","author":[{"given":"Karen E.","family":"Elkind-Hirsch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna","family":"Shaler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renee","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdiacomp.2020.107548_bb0005","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1016\/S0140-6736(09)60731-5","article-title":"Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis","volume":"373","author":"Bellamy","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0010","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.2337\/diacare.25.10.1862","article-title":"Gestational diabetes and the incidence of type 2 diabetes: a systematic review","volume":"25","author":"Kim","year":"2002","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0015","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.2337\/diabetes.51.9.2796","article-title":"Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk Hispanic women","volume":"51","author":"Buchanan","year":"2002","journal-title":"Diabetes"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0020","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2337\/diabetes.55.02.06.db05-1066","article-title":"Effect of pioglitazone on pancreatic B-cell function and diabetes risk is Hispanic women with prior gestational diabetes","volume":"55","author":"Xiang","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0025","doi-asserted-by":"crossref","first-page":"4774","DOI":"10.1210\/jc.2008-0772","article-title":"Prevention of diabetes in women with a history of gestational diabetes: effects of metformin and lifestyle interventions","volume":"93","author":"Ratner","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0030","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1111\/j.1365-2265.2010.03834.x","article-title":"Risk of early progression to re-diabetes or diabetes in women with recent gestational dysglycemia but normal glucose tolerance at 3-months postpartum","volume":"73","author":"Retnakaran","year":"2010","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0035","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.2337\/dc15-2672","article-title":"Heterogeneous contribution of insulin sensitivity and secretion defects to gestational diabetes mellitus","volume":"39","author":"Powe","year":"2016","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0040","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1210\/me.2002-0306","article-title":"Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis","volume":"17","author":"Drucker","year":"2003","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0045","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1007\/s00125-013-2841-0","article-title":"Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies","volume":"56","author":"Calanna","year":"2013","journal-title":"Diabetologia"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0050","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.2337\/db14-1751","article-title":"GLP-1 response to oral glucose is reduced in prediabetes, screen-detected type 2 diabetes, and obesity and influenced by sex: the ADDITION-PRO study","volume":"64","author":"F\u00e6rch","year":"2015","journal-title":"Diabetes"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0055","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1210\/jc.2015-3885","article-title":"Altered plasma levels of glucagon, GLP-1 and glicentin during OGTT in adolescents with obesity and type 2 diabetes","volume":"101","author":"Manell","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0060","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.2337\/db18-0254","article-title":"Reduced GLP-1 secretion at 30 minutes after a 75-g oral glucose load Is observed in gestational diabetes mellitus: a Prospective Cohort Study","volume":"67","author":"Sukumar","year":"2018","journal-title":"Diabetes"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0065","first-page":"e287","article-title":"Glucagon-like peptide-1 secretion in women with gestational diabetes mellitus during and after pregnancy","volume":"34","author":"Lencioni","year":"2011","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0070","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1210\/jc.2007-2109","article-title":"Incretin-based therapies in type 2 diabetes mellitus","volume":"93","author":"Chia","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0075","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1172\/JCI990","article-title":"Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans","volume":"101","author":"Flint","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0080","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s00125-013-3134-3","article-title":"Pancreatic beta cell function following liraglutide-augmented weight loss in individuals with prediabetes: analysis of a randomised, placebo-controlled study","volume":"57","author":"Kim","year":"2014","journal-title":"Diabetologia"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0085","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.2337\/dc07-0310","article-title":"Effects of the long-acting human glucagon-like peptide-1 analog liraglutide on beta-cell function in normal living conditions","volume":"30","author":"Mari","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0090","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1016\/S0140-6736(09)61375-1","article-title":"Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study","volume":"374","author":"Astrup","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0095","doi-asserted-by":"crossref","DOI":"10.1111\/j.1463-1326.2009.01158.x","article-title":"Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue","volume":"11","author":"Jendle","year":"2009","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0100","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1467-789X.2011.00952.x","article-title":"Waist-to-height ratio is a better screening tool than waist circumference and BMI for cardiometabolic risk factors: systemic review and meta-analysis","volume":"13","author":"Ashwell","year":"2012","journal-title":"Obes Rev"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0105","doi-asserted-by":"crossref","first-page":"361","DOI":"10.4158\/EP-2017-0251","article-title":"Short-term sitagliptin-metformin therapy is more effective than metformin or placebo in prior gestational diabetic women with impaired glucose regulation","author":"Elkind-Hirsch","year":"2018","journal-title":"Endocr Pract"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0110","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.fertnstert.2006.11.133","article-title":"Comparison of two doses of metformin (2.5 and 1.5 g\/day) for the treatment of polycystic ovary syndrome and their effect on body mass index and waist circumference","volume":"88","author":"Bruno","year":"2007","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0115","doi-asserted-by":"crossref","first-page":"84","DOI":"10.2337\/dc08-1355","article-title":"Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin in type 2 diabetes","volume":"32","author":"Nauck","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0120","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0140-6736(08)61246-5","article-title":"Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial","volume":"373","author":"Garber","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0125","first-page":"4382","article-title":"A meta-analysis of the effect of glucagon-like peptide-1 (7\u201336) amide on ad libitum energy intake in humans","volume":"86","author":"Verdich","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0130","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.2337\/dc10-0368","article-title":"Increases in waist circumference and weight as predictors of type 2 diabetes in individuals with impaired fasting glucose: influence of baseline BMI: data from the DESIR study","volume":"33","author":"Gautier","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0135","doi-asserted-by":"crossref","unstructured":"Fontbonne A, Charles MA, Juhan-Vague I, et al., BIGPRO Study Group The effect of metformin on the metabolic abnormalities associated with upper-body fat distribution. Diabetes Care 996; 19:920\u2013926.","DOI":"10.2337\/diacare.19.9.920"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0140","article-title":"Meta-analysis demonstrates that liraglutide, a once-daily human GLP-1 analogue, significantly reduces lipids and other markers of cardiovascular risk in T2D","volume":"52","author":"Plutzky","year":"2009","journal-title":"Diabetologia"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0145","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1185\/030079908X253870","article-title":"Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years","volume":"24","author":"Klonoff","year":"2008","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0150","doi-asserted-by":"crossref","DOI":"10.1002\/oby.20223","article-title":"Abdominal visceral fat measurement using dual-energy X-ray: association with cardiometabolic risk factors","volume":"21","author":"Rothney","year":"2013","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.jdiacomp.2020.107548_bb0155","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.2337\/dc20-S003","article-title":"Prevention or delay of type 2 diabetes: standards of medical care in diabetes 2020","volume":"43","author":"American Diabetes Association","year":"2020","journal-title":"Diabetes Care"}],"container-title":["Journal of Diabetes and its Complications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872719313194?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872719313194?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:09:26Z","timestamp":1761005366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1056872719313194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S1056872719313194"],"URL":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2020.107548","relation":{},"ISSN":["1056-8727"],"issn-type":[{"value":"1056-8727","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Postpartum treatment with liraglutide in combination with metformin versus metformin monotherapy to improve metabolic status and reduce body weight in overweight\/obese women with recent gestational diabetes: A double-blind, randomized, placebo-controlled study","name":"articletitle","label":"Article Title"},{"value":"Journal of Diabetes and its Complications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2020.107548","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"107548"}}