{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:31:29Z","timestamp":1789144289797,"version":"build-2803163510"},"reference-count":31,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes and its Complications"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.jdiacomp.2020.107611","type":"journal-article","created":{"date-parts":[[2020,5,3]],"date-time":"2020-05-03T19:51:36Z","timestamp":1588535496000},"page":"107611","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Autologous platelet-rich plasma treatment for patients with diabetic foot ulcers: a meta-analysis of randomized studies"],"prefix":"10.1016","volume":"34","author":[{"given":"Jiezhi","family":"Dai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoyin","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangbai","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jdiacomp.2020.107611_bb0005","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1056\/NEJMra1615439","article-title":"Diabetic foot ulcers and their recurrence","volume":"376","author":"Armstrong","year":"2017","journal-title":"New Engl J Med"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0010","article-title":"Assessment of the risk factors of multidrug-resistant organism infection in adults with type 1 or type 2 diabetes and diabetic foot ulcer","author":"Dai","year":"2019","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0015","doi-asserted-by":"crossref","first-page":"4893","DOI":"10.2174\/13816128113199990326","article-title":"Treatment of foot disease in patients with type 2 diabetes mellitus using human umbilical cord blood mesenchymal stem cells: response and correction of immunological anomalies","volume":"19","author":"Li","year":"2013","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0020","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.transci.2016.10.020","article-title":"Evaluation of wound healing in diabetic foot ulcer using platelet-rich plasma gel: a single-arm clinical trial","volume":"56","author":"Mohammadi","year":"2017","journal-title":"Transfus Apher Sci."},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0025","doi-asserted-by":"crossref","first-page":"5920676","DOI":"10.1155\/2019\/5920676","article-title":"Platelet-rich plasma with endothelial progenitor cells accelerates diabetic wound healing in rats by upregulating the Notch1 signaling pathway","volume":"2019","author":"Zhang","year":"2019","journal-title":"J Diabetes Res"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0030","doi-asserted-by":"crossref","first-page":"297","DOI":"10.2147\/IDR.S186651","article-title":"Platelet-rich plasma plays an antibacterial, anti-inflammatory and cell proliferation-promoting role in an in vitro model for diabetic infected wounds","volume":"12","author":"Li","year":"2019","journal-title":"Infect Drug Resist."},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0035","doi-asserted-by":"crossref","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0040","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2307\/2533446","article-title":"Operating characteristics of a rank correlation test for publication bias","volume":"50","author":"Begg","year":"1994","journal-title":"Biometrics"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0045","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0050","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.0006-341X.2000.00455.x","article-title":"Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"Duval","year":"2000","journal-title":"Biometrics"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0055","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0060","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.avsg.2016.04.023","article-title":"Platelet-rich plasma for the treatment of clean diabetic foot ulcers","volume":"38","author":"Ahmed","year":"2017","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0065","doi-asserted-by":"crossref","first-page":"550","DOI":"10.12968\/jowc.2018.27.9.550","article-title":"Role of platelet-rich plasma in healing diabetic foot ulcers: a prospective study","volume":"27","author":"Singh","year":"2018","journal-title":"J Wound Care"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0070","first-page":"68","article-title":"A prospective, randomized, controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers","volume":"52","author":"Driver","year":"2006","journal-title":"Ostomy Wound Manag."},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0075","article-title":"Randomized controlled trial on autologous platelet-rich plasma versus saline dressing in treatment of non-healing diabetic foot ulcers","author":"Elsaid","year":"2019","journal-title":"World J Surg"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0080","first-page":"495","article-title":"Autologous platelet-rich gel for treatment of diabetic chronic refractory cutaneous ulcers: a prospective, randomized clinical trial","volume":"23","author":"Li","year":"2015","journal-title":"Wound Repair Regen Off Publ Wound Heal Soc Eur Tiss Repair Soc"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0085","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/j.1742-481X.2011.00797.x","article-title":"Platelet-rich plasma versus platelet-poor plasma in the management of chronic diabetic foot ulcers: a comparative study","volume":"8","author":"Saad Setta","year":"2011","journal-title":"Int Wound J"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0090","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.jdiacomp.2007.03.006","article-title":"Synergistic action of protease-modulating matrix and autologous growth factors in healing of diabetic foot ulcers. A prospective randomized trial","volume":"21","author":"Kakagia","year":"2007","journal-title":"J Diabetes Complications"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0095","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0939-4753(04)80029-2","article-title":"A controlled study of the use of autologous platelet gel for the treatment of diabetic foot ulcers","volume":"14","author":"Saldalamacchia","year":"2004","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0100","article-title":"The effect of platelet rich plasma dressing on healing diabetic foot ulcers","volume":"5","author":"Karimi","year":"2016","journal-title":"Nurs Midwif Stud"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0105","series-title":"Fifth International Symposium Diabetic Foot Noordwijkerhout. The Netherlands","article-title":"The use of autologous platelet concentrate activated by autologous thrombin (APC+) is effective and safe in the treatment of chronic diabetic foot ulcers: a randomized controlled trial","author":"Friese","year":"2007"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s40141-013-0039-5","article-title":"PRP: review of the current evidence for musculoskeletal conditions","volume":"2","author":"Malanga","year":"2014","journal-title":"Curr Phys Med Rehab Rep"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0115","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.pmr.2016.06.002","article-title":"Platelet-rich plasma","volume":"27","author":"Wu","year":"2016","journal-title":"Phys Med Rehabil Clin N Am"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0120","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.dsx.2017.09.007","article-title":"Platelet rich plasma and growth factors cocktails for diabetic foot ulcers treatment: state of art developments and future prospects","volume":"12","author":"Gonchar","year":"2018","journal-title":"Diabetes Metab Syndr"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0125","first-page":"1","article-title":"Platelet-rich plasma: support for its use in wound healing","volume":"83","author":"Lacci","year":"2010","journal-title":"Yale J Biol Med"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0130","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1097\/PRS.0000000000006281","article-title":"The efficacy of platelet-rich plasma dressing for chronic nonhealing ulcers: a meta-analysis of 15 randomized controlled trials","volume":"144","author":"Xia","year":"2019","journal-title":"Plast Reconstruct Surg"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0135","first-page":"170","article-title":"Platelet-rich plasma for the treatment of diabetic foot ulcers: a meta-analysis","volume":"27","author":"Del Pino-Sede\u00f1o","year":"2019","journal-title":"Wound Repair Regen Off Publ Wound Heal Soc Eur Tissue Repair Soc"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0140","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1089\/wound.2018.0842","article-title":"Efficacy and safety of platelet-rich plasma for patients with diabetic ulcers: a systematic review and meta-analysis","volume":"8","author":"Hu","year":"2019","journal-title":"Adv Wound Care"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0145","doi-asserted-by":"crossref","first-page":"172","DOI":"10.4239\/wjd.v9.i10.172","article-title":"Topical application of platelet-rich plasma for diabetic foot ulcers: a systematic review","volume":"9","author":"Hirase","year":"2018","journal-title":"World J Diabetes."},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0150","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/1753-0407.12850","article-title":"Autologous platelet-rich gel treatment for diabetic chronic cutaneous ulcers: a meta-analysis of randomized controlled trials","volume":"11","author":"Li","year":"2019","journal-title":"J Diabetes"},{"key":"10.1016\/j.jdiacomp.2020.107611_bb0155","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.joms.2003.12.003","article-title":"Platelet-rich plasma: evidence to support its use","volume":"62","author":"Marx","year":"2004","journal-title":"J Oral Maxillofac Surg"}],"container-title":["Journal of Diabetes and its Complications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872720303676?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056872720303676?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:10:33Z","timestamp":1761005433000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1056872720303676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":31,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["S1056872720303676"],"URL":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2020.107611","relation":{},"ISSN":["1056-8727"],"issn-type":[{"value":"1056-8727","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Autologous platelet-rich plasma treatment for patients with diabetic foot ulcers: a meta-analysis of randomized studies","name":"articletitle","label":"Article Title"},{"value":"Journal of Diabetes and its Complications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jdiacomp.2020.107611","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"107611"}}