{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T09:14:16Z","timestamp":1769246056105,"version":"3.49.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,6]],"date-time":"2021-11-06T00:00:00Z","timestamp":1636156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dental Sciences"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.jds.2021.11.003","type":"journal-article","created":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T17:34:17Z","timestamp":1638984857000},"page":"707-717","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Knockdown of LncRNA NEAT1 inhibits myofibroblast activity in oral submucous fibrosis through miR-760\/TPM1 axis"],"prefix":"10.1016","volume":"17","author":[{"given":"Wei","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4666-3315","authenticated-orcid":false,"given":"Bin","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jds.2021.11.003_bib1","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.jobcr.2020.08.004","article-title":"Medicinal management of oral submucous fibrosis in the past decade- A systematic review","volume":"10","author":"More","year":"2020","journal-title":"J Oral Biol Craniofac Res"},{"key":"10.1016\/j.jds.2021.11.003_bib2","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.jobcr.2019.06.016","article-title":"Proposed clinical definition for oral submucous fibrosis","volume":"9","author":"More","year":"2019","journal-title":"J Oral Biol Craniofac Res"},{"key":"10.1016\/j.jds.2021.11.003_bib3","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.oraloncology.2005.08.005","article-title":"Oral submucous fibrosis: review on aetiology and pathogenesis","volume":"42","author":"Tilakaratne","year":"2006","journal-title":"Oral Oncol"},{"key":"10.1016\/j.jds.2021.11.003_bib4","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.jfma.2019.12.014","article-title":"Inhibition of HIF1A-AS1 impedes the arecoline-induced migration activity of human oral mucosal fibroblasts","volume":"119","author":"Wang","year":"2020","journal-title":"J Formos Med Assoc"},{"key":"10.1016\/j.jds.2021.11.003_bib5","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.jfma.2019.02.014","article-title":"miR-1246 as a therapeutic target in oral submucosa fibrosis pathogenesis","volume":"118","author":"Liu","year":"2019","journal-title":"J Formos Med Assoc"},{"key":"10.1016\/j.jds.2021.11.003_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0241901","article-title":"In\u00a0vitro mechanical vibration down-regulates pro-inflammatory and pro-fibrotic signaling in human vocal fold fibroblasts","volume":"15","author":"Hortobagyi","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jds.2021.11.003_bib7","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.3390\/ijms20061328","article-title":"Arctigenin reduces myofibroblast activities in oral submucous fibrosis by LINC00974 inhibition","volume":"20","author":"Lin","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jds.2021.11.003_bib8","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/jcmm.16097","article-title":"Impact of chronic intermittent hypoxia on the long non-coding RNA and mRNA expression profiles in myocardial infarction","volume":"25","author":"Hu","year":"2020","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.jds.2021.11.003_bib9","first-page":"1","article-title":"Evolutionary conservation of long non-coding RNAs in non-alcoholic fatty liver disease","volume":"264","author":"Rohilla","year":"2020","journal-title":"Life Sci"},{"key":"10.1016\/j.jds.2021.11.003_bib10","first-page":"1","article-title":"Long non-coding RNA expression profile associated with malignant progression of oral submucous fibrosis","volume":"2019","author":"Zhou","year":"2019","journal-title":"J Oncol"},{"key":"10.1016\/j.jds.2021.11.003_bib11","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1152\/ajprenal.00552.2019","article-title":"Long noncoding RNA NEAT1 sponges miR-129 to modulate renal fibrosis by regulation of collagen type I","volume":"319","author":"Li","year":"2020","journal-title":"Am J Physiol Ren Physiol"},{"key":"10.1016\/j.jds.2021.11.003_bib12","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1007\/s00109-017-1586-5","article-title":"NEAT1 accelerates the progression of liver fibrosis via regulation of microRNA-122 and Kruppel-like factor 6","volume":"95","author":"Yu","year":"2017","journal-title":"J Mol Med (Berl)"},{"key":"10.1016\/j.jds.2021.11.003_bib13","first-page":"1325","article-title":"LncRNA NEAT1 accelerates the occurrence and development of diabetic nephropathy by sponging miR-23c","volume":"24","author":"Li","year":"2020","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.jds.2021.11.003_bib14","first-page":"2243","article-title":"Long non-coding RNA NEAT1 promotes migration and invasion of oral squamous cell carcinoma cells by sponging microRNA-365","volume":"16","author":"Liu","year":"2018","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.jds.2021.11.003_bib15","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.jobcr.2021.03.007","article-title":"Conspicuous and frank dilated vascular spaces: a marker of malignant transformation in oral submucous fibrosis","volume":"11","author":"Sarode","year":"2021","journal-title":"J Oral Biol Craniofac Res"},{"key":"10.1016\/j.jds.2021.11.003_bib16","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1016\/j.jfma.2020.10.019","article-title":"Arecoline enhances miR-21 to promote buccal mucosal fibroblasts activation","volume":"120","author":"Yang","year":"2020","journal-title":"J Formos Med Assoc"},{"key":"10.1016\/j.jds.2021.11.003_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41419-019-1829-1","article-title":"LncRNA NR_003923 promotes cell proliferation, migration, fibrosis, and autophagy via the miR-760\/miR-215-3p\/IL22RA1 axis in human Tenon's capsule fibroblasts","volume":"10","author":"Zhao","year":"2019","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.jds.2021.11.003_bib18","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/jop.12431","article-title":"A preliminary microarray assay of the miRNA expression signatures in buccal mucosa of oral submucous fibrosis patients","volume":"45","author":"Chickooree","year":"2016","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.jds.2021.11.003_bib19","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/s13577-020-00453-4","article-title":"Circ0001320 inhibits lung cancer cell growth and invasion by regulating TNFAIP1 and TPM1 expression through sponging miR-558","volume":"34","author":"Mao","year":"2020","journal-title":"Hum Cell"},{"key":"10.1016\/j.jds.2021.11.003_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7754\/Clin.Lab.2019.190235","article-title":"TPM1 is a novel predictive biomarker for gastric cancer diagnosis and prognosis","volume":"66","author":"Hu","year":"2020","journal-title":"Clin Lab"},{"key":"10.1016\/j.jds.2021.11.003_bib21","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ijcard.2020.08.101","article-title":"The effect of tropomyosin variants on cardiomyocyte function and structure that underlie different clinical cardiomyopathy phenotypes","volume":"323","author":"Dorsch","year":"2020","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jds.2021.11.003_bib22","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.7150\/jca.28261","article-title":"Tropomyosin-1 functions as a tumor suppressor with respect to cell proliferation, angiogenesis and metastasis in renal cell carcinoma","volume":"10","author":"Wang","year":"2019","journal-title":"J Cancer"},{"key":"10.1016\/j.jds.2021.11.003_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphys.2020.00331","article-title":"The microRNA miR-29c alleviates renal fibrosis via TPM1-mediated suppression of the Wnt\/beta-catenin pathway","volume":"11","author":"Huang","year":"2020","journal-title":"Front Physiol"},{"key":"10.1016\/j.jds.2021.11.003_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13287-020-01990-3","article-title":"Si-SNHG5-FOXF2 inhibits TGF-beta1-induced fibrosis in human primary endometrial stromal cells by the Wnt\/beta-catenin signalling pathway","volume":"11","author":"Liu","year":"2020","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.jds.2021.11.003_bib25","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/jop.13096","article-title":"Expression and methylation of Dickkopf-1 in the pathogenesis and malignant transformation of oral submucous fibrosis","volume":"49","author":"He","year":"2020","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.jds.2021.11.003_bib26","first-page":"1","article-title":"Elevation of S100A4 expression in buccal mucosal fibroblasts by arecoline: involvement in the pathogenesis of oral submucous fibrosis","volume":"8","author":"Yu","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jds.2021.11.003_bib27","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/j.jfma.2020.03.005","article-title":"miR-10b regulated by Twist maintains myofibroblasts activities in oral submucous fibrosis","volume":"119","author":"Fang","year":"2020","journal-title":"J Formos Med Assoc"},{"key":"10.1016\/j.jds.2021.11.003_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fcell.2021.681529","article-title":"Long non-coding RNA TMEM220-AS1 suppressed hepatocellular carcinoma by regulating the miR-484\/MAGI1 axis as a competing endogenous RNA","volume":"9","author":"Cao","year":"2021","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.jds.2021.11.003_bib29","first-page":"1","article-title":"LINC00312\/YBX1 axis regulates myofibroblast activities in oral submucous fibrosis","volume":"21","author":"Yu","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jds.2021.11.003_bib30","doi-asserted-by":"crossref","first-page":"4668","DOI":"10.1002\/jcp.27267","article-title":"Angiotensin (1-7) inhibits arecoline-induced migration and collagen synthesis in human oral myofibroblasts via inhibiting NLRP3 inflammasome activation","volume":"234","author":"You","year":"2019","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.jds.2021.11.003_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-020-77207-7","article-title":"Long-term myofibroblast persistence in the capsular bag contributes to the late spontaneous in-the-bag intraocular lens dislocation","volume":"10","author":"Bisevac","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.jds.2021.11.003_bib32","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1165\/rcmb.2020-0121OC","article-title":"FK506-binding protein 13 expression is upregulated in interstitial lung disease and correlated with clinical severity: a potentially protective role","volume":"64","author":"Tat","year":"2021","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jds.2021.11.003_bib33","first-page":"8483","article-title":"LncRNA NEAT1 regulates pulmonary fibrosis through miR-9-5p and TGF-beta signaling pathway","volume":"24","author":"Zhang","year":"2020","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.jds.2021.11.003_bib34","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1186\/s12967-020-02577-5","article-title":"LncRNA NEAT1\/microRNA-129-5p\/SOCS2 axis regulates liver fibrosis in alcoholic steatohepatitis","volume":"18","author":"Ye","year":"2020","journal-title":"J Transl Med"},{"key":"10.1016\/j.jds.2021.11.003_bib35","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1684\/ecn.2019.0432","article-title":"lncRNA NEAT1 regulates fibrosis and inflammatory response induced by nonalcoholic fatty liver by regulating miR-506\/GLI3","volume":"30","author":"Jin","year":"2019","journal-title":"Eur Cytokine Netw"},{"key":"10.1016\/j.jds.2021.11.003_bib36","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1111\/odi.13008","article-title":"Pathogenesis investigation of miR-199-5p in oral submucous fibrosis based on bioinformatics analysis","volume":"25","author":"Yuan","year":"2019","journal-title":"Oral Dis"},{"key":"10.1016\/j.jds.2021.11.003_bib37","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0304-3835(02)00119-2","article-title":"Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells","volume":"183","author":"Bharadwaj","year":"2002","journal-title":"Cancer Lett"},{"key":"10.1016\/j.jds.2021.11.003_bib38","first-page":"1","article-title":"MiR-21 overexpression promotes esophageal squamous cell carcinoma invasion and migration by repressing tropomyosin 1","volume":"2020","author":"Shen","year":"2020","journal-title":"Gastroenterol Res Pract"},{"key":"10.1016\/j.jds.2021.11.003_bib39","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1080\/13880209.2020.1851729","article-title":"Arecoline suppresses epithelial cell viability by upregulating tropomyosin-1 through the transforming growth factor-beta\/Smad pathway","volume":"58","author":"Li","year":"2020","journal-title":"Pharm Biol"},{"key":"10.1016\/j.jds.2021.11.003_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ncomms1734","article-title":"Activation of canonical Wnt signalling is required for TGF-beta-mediated fibrosis","volume":"3","author":"Akhmetshina","year":"2012","journal-title":"Nat Commun"},{"key":"10.1016\/j.jds.2021.11.003_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jnutbio.2019.108266","article-title":"Epigallocatechin-3-gallate prevents TGF-beta1-induced epithelial-mesenchymal transition and fibrotic changes of renal cells via GSK-3beta\/beta-catenin\/Snail1 and Nrf2 pathways","volume":"76","author":"Kanlaya","year":"2020","journal-title":"J Nutr Biochem"}],"container-title":["Journal of Dental Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1991790221002683?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1991790221002683?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T19:16:23Z","timestamp":1761851783000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1991790221002683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S1991790221002683"],"URL":"https:\/\/doi.org\/10.1016\/j.jds.2021.11.003","relation":{},"ISSN":["1991-7902"],"issn-type":[{"value":"1991-7902","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Knockdown of LncRNA NEAT1 inhibits myofibroblast activity in oral submucous fibrosis through miR-760\/TPM1 axis","name":"articletitle","label":"Article Title"},{"value":"Journal of Dental Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jds.2021.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}