{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:43:02Z","timestamp":1792683782273,"version":"4.5.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82074502"],"award-info":[{"award-number":["82074502"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82101008"],"award-info":[{"award-number":["82101008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dental Sciences"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.jds.2022.08.007","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T11:47:19Z","timestamp":1661514439000},"page":"475-478","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Perspectives on salivary cytokines as noninvasive biomarkers for monitoring disease activity and therapeutic response of oral lichen planus"],"prefix":"10.1016","volume":"18","author":[{"given":"Wei","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanhuan","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jds.2022.08.007_bib1","article-title":"Immune mechanisms in oral lichen planus","author":"El-Howati","year":"2022","journal-title":"Oral Dis"},{"key":"10.1016\/j.jds.2022.08.007_bib2","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.jds.2021.10.002","article-title":"Direct immunofluorescence and immune function in patients with oral lichen planus","volume":"17","author":"Mao","year":"2022","journal-title":"J Dent Sci"},{"key":"10.1016\/j.jds.2022.08.007_bib3","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.jds.2021.03.012","article-title":"Intralesional and peripheral plasma of oral lichenoid reactions exhibit different cytokine profiles: a preliminary study","volume":"17","author":"Sun","year":"2022","journal-title":"J Dent Sci"},{"key":"10.1016\/j.jds.2022.08.007_bib4","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jds.2021.06.013","article-title":"Salivary cytokine profile in patients with oral lichen planus","volume":"17","author":"Zhu","year":"2022","journal-title":"J Dent Sci"},{"key":"10.1016\/j.jds.2022.08.007_bib5","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.oooo.2018.02.013","article-title":"Mixed and inhomogeneous expression profile of Th1\/Th2 related cytokines detected by cytometric bead array in the saliva of patients with oral lichen planus","volume":"126","author":"Wei","year":"2018","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.jds.2022.08.007_bib6","doi-asserted-by":"crossref","first-page":"5649","DOI":"10.1007\/s00784-021-03867-y","article-title":"High-level laser therapy versus scalpel surgery in the treatment of oral lichen planus: a randomized control trial","volume":"25","author":"Tarasenko","year":"2021","journal-title":"Clin Oral Invest"},{"key":"10.1016\/j.jds.2022.08.007_bib7","article-title":"Serum and salivary cytokines in patients with oral lichen planus treated with Photobiomodulation","author":"Abboud","year":"2021","journal-title":"Oral Dis"},{"key":"10.1016\/j.jds.2022.08.007_bib8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/ijd.12887","article-title":"Clinical and serological efficacy of topical calcineurin inhibitors in oral lichen planus: a prospective randomized controlled trial","volume":"55","author":"Vohra","year":"2016","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jds.2022.08.007_bib9","doi-asserted-by":"crossref","first-page":"e477","DOI":"10.4317\/jced.52376","article-title":"Role of serum interleukin-6 in deciding therapy for multidrug resistant oral lichen planus","volume":"7","author":"Goel","year":"2015","journal-title":"J Clin Exp Dent"},{"key":"10.1016\/j.jds.2022.08.007_bib10","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1007\/s00784-013-1176-z","article-title":"Hydroxychloroquine decreases the upregulated frequencies of Tregs in patients with oral lichen planus","volume":"18","author":"Zhu","year":"2014","journal-title":"Clin Oral Invest"},{"key":"10.1016\/j.jds.2022.08.007_bib11","doi-asserted-by":"crossref","DOI":"10.1155\/2010\/847632","article-title":"Levels of salivary IFN-gamma, TNF-alfa, and TNF receptor-2 as prognostic markers in (erosive) oral lichen planus","volume":"2010","author":"Ghallab","year":"2010","journal-title":"Mediat Inflamm"},{"key":"10.1016\/j.jds.2022.08.007_bib12","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/j.1600-0714.2009.00805.x","article-title":"Expression of IFN- gamma before and after treatment of oral lichen planus with 0.1% fluocinolone acetonide in orabase","volume":"38","author":"Youngnak-Piboonratanakit","year":"2009","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.jds.2022.08.007_bib13","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1601-0825.2005.01165.x","article-title":"Proinflammatory cytokine levels in saliva before and after treatment of (erosive) oral lichen planus with dexamethasone","volume":"12","author":"Rhodus","year":"2006","journal-title":"Oral Dis"},{"key":"10.1016\/j.jds.2022.08.007_bib14","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1111\/j.1365-2133.2005.06497.x","article-title":"Serum interleukin-8 level is a more sensitive marker than serum interleukin-6 level in monitoring the disease activity of oral lichen planus","volume":"152","author":"Sun","year":"2005","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jds.2022.08.007_bib15","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1034\/j.1600-0714.2002.310402.x","article-title":"Serum interleukin-6 level is a useful marker in evaluating therapeutic effects of levamisole and Chinese medicinal herbs on patients with oral lichen planus","volume":"31","author":"Sun","year":"2002","journal-title":"J Oral Pathol Med"}],"container-title":["Journal of Dental Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1991790222001908?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1991790222001908?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T19:14:14Z","timestamp":1761851654000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1991790222001908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S1991790222001908"],"URL":"https:\/\/doi.org\/10.1016\/j.jds.2022.08.007","relation":{},"ISSN":["1991-7902"],"issn-type":[{"value":"1991-7902","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Perspectives on salivary cytokines as noninvasive biomarkers for monitoring disease activity and therapeutic response of oral lichen planus","name":"articletitle","label":"Article Title"},{"value":"Journal of Dental Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jds.2022.08.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}