{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:40:13Z","timestamp":1786992013232,"version":"build-2736575974"},"reference-count":62,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002799","name":"Capital Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002799","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370989"],"award-info":[{"award-number":["82370989"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["CXTD202203"],"award-info":[{"award-number":["CXTD202203"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Evidence-Based Dental Practice"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jebdp.2025.102172","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T20:07:53Z","timestamp":1750277273000},"page":"102172","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["THE ASSOCIATION BETWEEN PERIODONTAL DISEASE AND STROKE RISK: A SYSTEMATIC REVIEW AND META-ANALYSIS"],"prefix":"10.1016","volume":"25","author":[{"given":"YUQING","family":"ZHANG","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CE","family":"BIAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHAORAN","family":"YU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MENGYAO","family":"ZHU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MICHAEL D.","family":"WEIR","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HOCKIN H.K.","family":"XU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YUXING","family":"BAI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3094-9826","authenticated-orcid":false,"given":"NING","family":"ZHANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0001","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1186\/s12903-024-04907-1","article-title":"Periodontal disease and cardiovascular disease: umbrella review","volume":"24","author":"Arbildo-Vega","year":"2024","journal-title":"BMC Oral Health"},{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0002","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4103\/jfmpc.jfmpc_1810_21","article-title":"Association between obesity and periodontal disease among 35 - 44 years old patients visiting Teerthanker Mahaveer Dental College and Research Centre, Moradabad: a cross sectional study","volume":"12","author":"Sahar","year":"2023","journal-title":"J Fam Med Prim Care"},{"issue":"6","key":"10.1016\/j.jebdp.2025.102172_bib0003","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/s41569-022-00825-3","article-title":"The oral microbiome in the pathophysiology of cardiovascular disease","volume":"20","author":"Tonelli","year":"2023","journal-title":"Nat Rev Cardiol"},{"issue":"7","key":"10.1016\/j.jebdp.2025.102172_bib0004","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/s11883-020-00848-6","article-title":"Periodontal inflammation and the risk of cardiovascular disease","volume":"22","author":"Priyamvara","year":"2020","journal-title":"Curr Atheroscler Rep"},{"issue":"2","key":"10.1016\/j.jebdp.2025.102172_bib0005","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1177\/0022034518814829","article-title":"Tooth loss predicts myocardial infarction, heart failure, stroke, and death","volume":"98","author":"Lee","year":"2019","journal-title":"J Dent Res"},{"issue":"8","key":"10.1016\/j.jebdp.2025.102172_bib0006","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1161\/CIRCULATIONAHA.116.025250","article-title":"Prevalence, incidence, and mortality of stroke in China: results from a nationwide population-based survey of 480 687 adults","volume":"135","author":"Wang","year":"2017","journal-title":"Circulation"},{"issue":"10446","key":"10.1016\/j.jebdp.2025.102172_bib0007","doi-asserted-by":"crossref","first-page":"2820","DOI":"10.1016\/S0140-6736(24)00642-1","article-title":"Stroke","volume":"403","author":"Hilkens","year":"2024","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0008","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s13054-023-04786-y","article-title":"Remote ischemic conditioning reduces adverse events in patients with acute ischemic stroke complicating acute myocardial infarction: a randomized controlled trial","volume":"28","author":"Li","year":"2024","journal-title":"Crit Care"},{"issue":"9945","key":"10.1016\/j.jebdp.2025.102172_bib0009","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0140-6736(14)60460-8","article-title":"Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the global burden of disease study 2013","volume":"384","author":"Ng","year":"2014","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.jebdp.2025.102172_bib0010","doi-asserted-by":"crossref","first-page":"3651","DOI":"10.1161\/STROKEAHA.111.635755","article-title":"Stroke and stroke care in China: huge burden, significant workload, and a national priority","volume":"42","author":"Liu","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.jebdp.2025.102172_bib0011","article-title":"Association between periodontal disease and atherosclerotic cardiovascular diseases: revisited","volume":"7","author":"Zardawi","year":"2020","journal-title":"Front Cardiovasc Med"},{"issue":"2","key":"10.1016\/j.jebdp.2025.102172_bib0012","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1161\/STROKEAHA.117.018990","article-title":"Periodontal disease, regular dental care use, and incident ischemic stroke","volume":"49","author":"Sen","year":"2018","journal-title":"Stroke"},{"issue":"4","key":"10.1016\/j.jebdp.2025.102172_bib0013","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.004518","article-title":"History of periodontitis diagnosis and edentulism as predictors of cardiovascular disease, stroke, and mortality in postmenopausal women","volume":"6","author":"LaMonte","year":"2017","journal-title":"J Am Heart Assoc"},{"issue":"9","key":"10.1016\/j.jebdp.2025.102172_bib0014","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0290545","article-title":"Periodontal disease and subsequent risk of cardiovascular outcome and all-cause mortality: a meta-analysis of prospective studies","volume":"18","author":"Guo","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.jebdp.2025.102172_bib0015","doi-asserted-by":"crossref","first-page":"519","DOI":"10.2147\/VHRM.S204097","article-title":"Periodontitis as a risk factor for stroke: a systematic review and meta-analysis","volume":"15","author":"Fagundes","year":"2019","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.jebdp.2025.102172_bib0016","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.jebdp.2025.102172_bib0017","unstructured":"BS GA Wells, D O'Connell, J Peterson, V Welch, M Losos, P Tugwell, The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Available at: https:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp."},{"key":"10.1016\/j.jebdp.2025.102172_bib0018","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/1471-2458-13-154","article-title":"Are healthcare workers' intentions to vaccinate related to their knowledge, beliefs and attitudes? A systematic review","volume":"13","author":"Herzog","year":"2013","journal-title":"BMC Public Health"},{"key":"10.1016\/j.jebdp.2025.102172_bib0019","article-title":"Does periodontitis increase the risk for future cardiovascular events? Long-term follow-up of the PAROKRANK study","author":"Norhammar","year":"2024","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.jebdp.2025.102172_bib0020","article-title":"Association between gingivitis, tooth loss and cardiovascular risk: insights from a 10-year nationwide cohort study of 3.7 million Koreans","volume":"19","author":"Lee","year":"2024","journal-title":"PLoS ONE"},{"issue":"12","key":"10.1016\/j.jebdp.2025.102172_bib0021","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1002\/JPER.21-0528","article-title":"Periodontitis is a potential risk factor for transient ischemic attack and minor ischemic stroke in young adults: a nationwide population-based cohort study","volume":"93","author":"Lee","year":"2022","journal-title":"J Periodontol"},{"issue":"10","key":"10.1016\/j.jebdp.2025.102172_bib0022","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1097\/JCMA.0000000000000797","article-title":"Patients with periodontitis are at a higher risk of stroke: a Taiwanese cohort study","volume":"85","author":"Hsu","year":"2022","journal-title":"J Chin Med Assoc"},{"issue":"12","key":"10.1016\/j.jebdp.2025.102172_bib0023","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-048296","article-title":"Burden of chronic diseases associated with periodontal diseases: a retrospective cohort study using UK primary care data","volume":"11","author":"Zemedikun","year":"2021","journal-title":"BMJ Open"},{"issue":"3","key":"10.1016\/j.jebdp.2025.102172_bib0024","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/jcpe.13418","article-title":"Periodontitis is associated with cardiovascular diseases: a 13-year study","volume":"48","author":"Tiensripojamarn","year":"2021","journal-title":"J Clin Periodontol"},{"issue":"7","key":"10.1016\/j.jebdp.2025.102172_bib0025","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1177\/0022034520986097","article-title":"Severe periodontal disease increases acute myocardial infarction and stroke: a 10-year retrospective follow-up study","volume":"100","author":"Cho","year":"2021","journal-title":"J Dent Res"},{"issue":"6","key":"10.1016\/j.jebdp.2025.102172_bib0026","doi-asserted-by":"crossref","first-page":"4085","DOI":"10.1007\/s00784-020-03739-x","article-title":"Periodontitis related to cardiovascular events and mortality: a long-time longitudinal study","volume":"25","author":"Bengtsson","year":"2021","journal-title":"Clin Oral Invest"},{"issue":"26","key":"10.1016\/j.jebdp.2025.102172_bib0027","doi-asserted-by":"crossref","first-page":"e7398","DOI":"10.1097\/MD.0000000000007398","article-title":"Association between periodontal disease and non-communicable diseases: a 12-year longitudinal health-examinee cohort study in South Korea","volume":"96","author":"Lee","year":"2017","journal-title":"Medicine (Baltimore)"},{"issue":"4","key":"10.1016\/j.jebdp.2025.102172_bib0028","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.amjcard.2016.05.036","article-title":"Relation of periodontitis to risk of cardiovascular and all-cause mortality (from a Danish Nationwide Cohort Study)","volume":"118","author":"Hansen","year":"2016","journal-title":"Am J Cardiol"},{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0029","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/jcpe.12335","article-title":"Cardiovascular risks associated with incident and prevalent periodontal disease","volume":"42","author":"Yu","year":"2015","journal-title":"J Clin Periodontol"},{"issue":"9","key":"10.1016\/j.jebdp.2025.102172_bib0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0137142","article-title":"Gingival inflammation associates with stroke\u2013a role for oral health personnel in prevention: a database study","volume":"10","author":"Soder","year":"2015","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jebdp.2025.102172_bib0031","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1161\/STROKEAHA.111.000076","article-title":"Dental prophylaxis and periodontal treatment are protective factors to ischemic stroke","volume":"44","author":"Lee","year":"2013","journal-title":"Stroke"},{"issue":"5","key":"10.1016\/j.jebdp.2025.102172_bib0032","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1093\/aje\/kwp177","article-title":"Do genetic factors explain the association between poor oral health and cardiovascular disease? a prospective study among Swedish twins","volume":"170","author":"Mucci","year":"2009","journal-title":"Am J Epidemiol"},{"issue":"4","key":"10.1016\/j.jebdp.2025.102172_bib0033","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/ana.21742","article-title":"Periodontitis and incidence of cerebrovascular disease in men","volume":"66","author":"Jimenez","year":"2009","journal-title":"Ann Neurol"},{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0034","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1161\/01.STR.0000052974.79428.0C","article-title":"Periodontal disease, tooth loss, and incidence of ischemic stroke","volume":"34","author":"Joshipura","year":"2003","journal-title":"Stroke"},{"issue":"2","key":"10.1016\/j.jebdp.2025.102172_bib0035","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0735-1097(00)01130-X","article-title":"Periodontal disease and risk of subsequent cardiovascular disease in U.S. male physicians","volume":"37","author":"Howell","year":"2001","journal-title":"J Am Coll Cardiol"},{"issue":"18","key":"10.1016\/j.jebdp.2025.102172_bib0036","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1001\/archinte.160.18.2749","article-title":"Periodontal disease and risk of cerebrovascular disease: the first national health and nutrition examination survey and its follow-up study","volume":"160","author":"Wu","year":"2000","journal-title":"Arch Intern Med"},{"issue":"8","key":"10.1016\/j.jebdp.2025.102172_bib0037","article-title":"Markers of periodontal disease and risk of stroke: INTERSTROKE case-control study","volume":"33","author":"Murphy","year":"2024","journal-title":"J Strok Cerebrovasv Dis"},{"issue":"5","key":"10.1016\/j.jebdp.2025.102172_bib0038","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1177\/00220345241232406","article-title":"Periodontitis, dental procedures, and young-onset cryptogenic stroke","volume":"103","author":"Leskel\u00e4","year":"2024","journal-title":"J Dent Res"},{"issue":"10","key":"10.1016\/j.jebdp.2025.102172_bib0039","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1111\/ene.13080","article-title":"Chronic periodontitis is associated with lacunar infarct: a case-control study","volume":"23","author":"Leira","year":"2016","journal-title":"Eur J Neurol"},{"issue":"12","key":"10.1016\/j.jebdp.2025.102172_bib0040","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1016\/j.puhe.2015.02.033","article-title":"Stroke and periodontal disease in Senegal: case-control study","volume":"129","author":"Diouf","year":"2015","journal-title":"Pub Health"},{"issue":"8","key":"10.1016\/j.jebdp.2025.102172_bib0041","doi-asserted-by":"crossref","first-page":"687","DOI":"10.3109\/00016357.2014.898089","article-title":"Association between periodontal disease and non-fatal ischemic stroke: a case-control study","volume":"72","author":"Lafon","year":"2014","journal-title":"Acta Odontol Scand"},{"issue":"2","key":"10.1016\/j.jebdp.2025.102172_bib0042","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1600-0765.2009.01220.x","article-title":"Periodontitis as a risk factor for cerebrovascular accident: a case-control study in the Indian population","volume":"45","author":"Pradeep","year":"2010","journal-title":"J Periodontal Res"},{"issue":"5","key":"10.1016\/j.jebdp.2025.102172_bib0043","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1902\/jop.2010.090614","article-title":"Association between periodontitis and hemorrhagic stroke among Koreans: a case-control study","volume":"81","author":"Kim","year":"2010","journal-title":"J Periodontol"},{"issue":"9","key":"10.1016\/j.jebdp.2025.102172_bib0044","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1902\/jop.2008.080015","article-title":"Periodontitis and the risk for non-fatal stroke in Korean adults","volume":"79","author":"Sim","year":"2008","journal-title":"J Periodontol"},{"issue":"5","key":"10.1016\/j.jebdp.2025.102172_bib0045","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1111\/j.1600-051x.2004.00579.x","article-title":"The association of gingivitis and periodontitis with ischemic stroke","volume":"31","author":"Dorfer","year":"2004","journal-title":"J Clin Periodontol"},{"issue":"5","key":"10.1016\/j.jebdp.2025.102172_bib0046","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1002\/JPER.23-0008","article-title":"Relationship between C-reactive protein level and periodontitis and systemic diseases","volume":"95","author":"Lee","year":"2024","journal-title":"J Periodontol"},{"issue":"2","key":"10.1016\/j.jebdp.2025.102172_bib0047","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/idh.12785","article-title":"Association between multimorbidity and periodontal disease in Korean adults: a nationwide cross-sectional cohort study","volume":"22","author":"Jung","year":"2024","journal-title":"Int J Dent Hyg"},{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0048","article-title":"Periodontitis is associated with stroke","volume":"21","author":"Zheng","year":"2023","journal-title":"J Translation Med"},{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0049","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jds.2020.05.006","article-title":"Association between periodontal health and stroke: results from the 2013-2015 Korea National Health and Nutrition Examination Survey (KNHANES)","volume":"16","author":"Cho","year":"2021","journal-title":"J Dent Scien"},{"issue":"14","key":"10.1016\/j.jebdp.2025.102172_bib0050","first-page":"1","article-title":"Cross-sectional analysis of the association between periodontitis and cardiovascular disease using the korean genome and epidemiology study data","volume":"17","author":"Byun","year":"2020","journal-title":"Int J Environment Res Pub Heal"},{"issue":"4","key":"10.1016\/j.jebdp.2025.102172_bib0051","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0214731","article-title":"Association between periodontitis and cardiometabolic risk: results from the Korean National Health and Nutrition Examination Survey 2008-2014","volume":"14","author":"Kang","year":"2019","journal-title":"PLoS ONE"},{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0052","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1902\/annals.1998.3.1.161","article-title":"The relationship between dental disease and cerebral vascular accident in elderly United States veterans","volume":"3","author":"Loesche","year":"1998","journal-title":"Ann Periodontol"},{"issue":"5","key":"10.1016\/j.jebdp.2025.102172_bib0053","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1093\/ije\/dys147","article-title":"Case-control studies: basic concepts","volume":"41","author":"Vandenbroucke","year":"2012","journal-title":"Int J Epidemiol"},{"issue":"3","key":"10.1016\/j.jebdp.2025.102172_bib0054","doi-asserted-by":"crossref","first-page":"407","DOI":"10.17219\/dmp\/158793","article-title":"Association of periodontitis and gingivitis with stroke: a systematic review and meta-analysis","volume":"61","author":"Dewan","year":"2024","journal-title":"Dent Med Probl"},{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0055","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1902\/jop.2004.75.1.146","article-title":"Locally produced anti-phosphorylcholine and anti-oxidized low-density lipoprotein antibodies in gingival crevicular fluid from aggressive periodontitis patients","volume":"75","author":"Schenkein","year":"2004","journal-title":"J Periodontol"},{"issue":"6","key":"10.1016\/j.jebdp.2025.102172_bib0056","doi-asserted-by":"crossref","first-page":"3178","DOI":"10.4049\/jimmunol.1201053","article-title":"Microbial carriage state of peripheral blood dendritic cells (DCs) in chronic periodontitis influences DC differentiation, atherogenic potential","volume":"189","author":"Carrion","year":"2012","journal-title":"J Immunol"},{"issue":"9","key":"10.1016\/j.jebdp.2025.102172_bib0057","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1902\/jop.2014.130604","article-title":"Quantification of periodontal pathogens in vascular, blood, and subgingival samples from patients with peripheral arterial disease or abdominal aortic aneurysms","volume":"85","author":"Figuero","year":"2014","journal-title":"J Periodontol"},{"issue":"2","key":"10.1016\/j.jebdp.2025.102172_bib0058","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.micpath.2007.08.011","article-title":"Aggregatibacter actinomycetemcomitans induces MMP-9 expression and proatherogenic lipoprotein profile in apoE-deficient mice","volume":"44","author":"Tuomainen","year":"2008","journal-title":"Microb Pathog"},{"issue":"4","key":"10.1016\/j.jebdp.2025.102172_bib0059","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1600-0765.2008.01122.x","article-title":"Periodontitis-induced lipid peroxidation in rat descending aorta is involved in the initiation of atherosclerosis","volume":"44","author":"Ekuni","year":"2009","journal-title":"J Periodontal Res"},{"key":"10.1016\/j.jebdp.2025.102172_bib0060","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3389\/fimmu.2018.00430","article-title":"C-reactive protein in atherothrombosis and angiogenesis","volume":"9","author":"Badimon","year":"2018","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.jebdp.2025.102172_bib0061","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1111\/jre.12172","article-title":"Assessment of high-sensitivity C-reactive protein and lipid levels in healthy adults and patients with coronary artery disease, with and without periodontitis\u2013a cross-sectional study","volume":"49","author":"Kumar","year":"2014","journal-title":"J Periodontal Res"},{"issue":"1","key":"10.1016\/j.jebdp.2025.102172_bib0062","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/omi.12067","article-title":"The role of Porphyromonas gingivalis gingipains in platelet activation and innate immune modulation","volume":"30","author":"Klarstrom Engstrom","year":"2015","journal-title":"Mol Oral Microbiol"}],"container-title":["Journal of Evidence-Based Dental Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532338225000879?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532338225000879?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T08:07:57Z","timestamp":1763885277000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532338225000879"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":62,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1532338225000879"],"URL":"https:\/\/doi.org\/10.1016\/j.jebdp.2025.102172","relation":{},"ISSN":["1532-3382"],"issn-type":[{"value":"1532-3382","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"THE ASSOCIATION BETWEEN PERIODONTAL DISEASE AND STROKE RISK: A SYSTEMATIC REVIEW AND META-ANALYSIS","name":"articletitle","label":"Article Title"},{"value":"Journal of Evidence-Based Dental Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jebdp.2025.102172","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102172"}}