{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T14:03:14Z","timestamp":1762005794431,"version":"build-2065373602"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T00:00:00Z","timestamp":1668297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jctecasereports.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical and Translational Endocrinology: Case Reports"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.jecr.2022.100138","type":"journal-article","created":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T23:16:24Z","timestamp":1668640584000},"page":"100138","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Role of the immune system and possible mechanisms in COVID-19 vaccine-induced thyroiditis: Case report and literature review"],"prefix":"10.1016","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0965-0486","authenticated-orcid":false,"given":"Vahid","family":"Reisi-Vanani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahour","family":"Farzan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahan","family":"Farzan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hosein","family":"Ataei-Goujani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Keihani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Golshan","family":"Taghipour-Boroujeni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jecr.2022.100138_bib1","first-page":"1","article-title":"Two important issues in subacute thyroiditis management: delayed diagnosis and inappropriate use of antibiotics","author":"Bostan","year":"2021","journal-title":"European Thyroid Journal"},{"issue":"11","key":"10.1016\/j.jecr.2022.100138_bib2","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1055\/a-0998-8035","article-title":"Long-term outcome of subacute thyroiditis","volume":"128","author":"G\u00f6rges","year":"2020","journal-title":"Exp Clin Endocrinol Diabetes"},{"issue":"3","key":"10.1016\/j.jecr.2022.100138_bib3","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1007\/s12020-021-02807-w","article-title":"Modulation of ACE-2 mRNA by inflammatory cytokines in human thyroid cells: a pilot study","volume":"74","author":"Coperchini","year":"2021","journal-title":"Endocrine"},{"key":"10.1016\/j.jecr.2022.100138_bib4","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/978-3-030-62011-0_16","article-title":"Subacute (de Quervain's) thyroiditis","author":"Reismann","year":"2021","journal-title":"Pract. Clin. Endocrinol."},{"issue":"10","key":"10.1016\/j.jecr.2022.100138_bib5","doi-asserted-by":"crossref","first-page":"e3742","DOI":"10.1210\/clinem\/dgaa537","article-title":"Is subacute thyroiditis an underestimated manifestation of SARS-CoV-2 infection? Insights from a case series","volume":"105","author":"Brancatella","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.jecr.2022.100138_bib6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s42000-020-00230-w","article-title":"Subacute thyroiditis in a patient infected with SARS-COV-2: an endocrine complication linked to the COVID-19 pandemic","volume":"20","author":"Ruggeri","year":"2021","journal-title":"Hormones (Basel)"},{"key":"10.1016\/j.jecr.2022.100138_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.metop.2021.100136","article-title":"Thyroiditis following vaccination against COVID-19: report of two cases and review of the literature","author":"Siolos","year":"2021","journal-title":"Metabolism open"},{"issue":"1","key":"10.1016\/j.jecr.2022.100138_bib8","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.jhep.2021.04.003","article-title":"Autoimmune hepatitis developing after coronavirus disease 2019 (COVID-19) vaccine: causality or casualty?","volume":"75","author":"Bril","year":"2021","journal-title":"J Hepatol"},{"key":"10.1016\/j.jecr.2022.100138_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2021.102706","article-title":"Acute autoimmune-like hepatitis with atypical anti-mitochondrial antibody after mRNA COVID-19 vaccination: a novel clinical entity?","volume":"123","author":"Ghielmetti","year":"2021","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jecr.2022.100138_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2021.102710","article-title":"Autoimmune hepatitis triggered by SARS-CoV-2 vaccination","volume":"123","author":"Vuille-Lessard","year":"2021","journal-title":"J Autoimmun"},{"issue":"9","key":"10.1016\/j.jecr.2022.100138_bib11","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1089\/thy.2021.0142","article-title":"Two cases of graves' disease following SARS-CoV-2 vaccination: an autoimmune\/inflammatory syndrome induced by adjuvants","volume":"31","year":"2021","journal-title":"Thyroid"},{"key":"10.1016\/j.jecr.2022.100138_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2021.102738","article-title":"A case of Graves' disease and type 1 diabetes mellitus following SARS-CoV-2 vaccination","volume":"125","author":"Patrizio","year":"2021","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jecr.2022.100138_bib13","doi-asserted-by":"crossref","DOI":"10.1210\/clinem\/dgab373","article-title":"Three cases of subacute thyroiditis following SARS-CoV-2 vaccine: post-vaccination ASIA syndrome","author":"\u0130remli","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"issue":"11","key":"10.1016\/j.jecr.2022.100138_bib14","article-title":"COVID-19 vaccine-associated subacute thyroiditis: an unusual suspect for de Quervain's thyroiditis","volume":"14","author":"Jeeyavudeen","year":"2021","journal-title":"BMJ Case Reports CP"},{"key":"10.1016\/j.jecr.2022.100138_bib15","doi-asserted-by":"crossref","first-page":"3679","DOI":"10.3389\/fimmu.2020.617089","article-title":"Reaction of human monoclonal antibodies to SARS-CoV-2 proteins with tissue antigens: implications for autoimmune diseases","volume":"11","author":"Vojdani","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.jecr.2022.100138_bib16","doi-asserted-by":"crossref","first-page":"150","DOI":"10.3389\/fendo.2016.00150","article-title":"Autoimmune\/inflammatory syndrome induced by adjuvants and thyroid autoimmunity","volume":"7","author":"Watad","year":"2017","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.jecr.2022.100138_bib17","first-page":"1","article-title":"Post-COVID-vaccine autoimmune\/inflammatory syndrome in response to adjuvants (ASIA syndrome) manifesting as subacute thyroiditis","author":"Das","year":"2021","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.jecr.2022.100138_bib18","article-title":"A case of hypophysitis following immunization with the mRNA-1273 SARS-CoV-2 vaccine","volume":"9","author":"Murvelashvili","year":"2021","journal-title":"J Invest Med High Impact Case Rep."},{"issue":"1","key":"10.1016\/j.jecr.2022.100138_bib19","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.jaut.2010.07.003","article-title":"\u2018ASIA\u2019\u2013autoimmune\/inflammatory syndrome induced by adjuvants","volume":"36","author":"Shoenfeld","year":"2011","journal-title":"J Autoimmun"},{"issue":"2","key":"10.1016\/j.jecr.2022.100138_bib20","doi-asserted-by":"crossref","first-page":"534","DOI":"10.3390\/jcm9020534","article-title":"Subacute thyroiditis is associated with HLA-B* 18: 01,-DRB1* 01 and-C* 04: 01\u2014the significance of the new molecular background","volume":"9","author":"Stasiak","year":"2020","journal-title":"J Clin Med"},{"issue":"5","key":"10.1016\/j.jecr.2022.100138_bib21","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.3390\/ijms20051089","article-title":"The risk of recurrence of subacute thyroiditis is HLA-dependent","volume":"20","author":"Stasiak","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"12","key":"10.1016\/j.jecr.2022.100138_bib22","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1078\/0344-0338-00344","article-title":"Cellular composition of subacute thyroiditis. an immunohistochemical study of six cases","volume":"198","author":"Kojima","year":"2002","journal-title":"Pathol Res Pract"},{"issue":"6","key":"10.1016\/j.jecr.2022.100138_bib23","article-title":"Subacute thyroiditis after receiving the adenovirus-vectored vaccine for coronavirus disease (COVID-19)","volume":"13","author":"Oyibo","year":"2021","journal-title":"Cureus"},{"key":"10.1016\/j.jecr.2022.100138_bib24","first-page":"1","article-title":"Subacute thyroiditis following COVID-19 vaccination in a 67-year-old male patient: a case report","author":"\u015eahin Tekin","year":"2021","journal-title":"Hum Vaccines Immunother"},{"issue":"10","key":"10.1016\/j.jecr.2022.100138_bib25","article-title":"Subacute thyroiditis after inactive SARS-CoV-2 vaccine","volume":"14","author":"Sayg\u0131l\u0131","year":"2021","journal-title":"BMJ Case Reports CP"},{"issue":"10","key":"10.1016\/j.jecr.2022.100138_bib26","doi-asserted-by":"crossref","DOI":"10.1002\/ccr3.4812","article-title":"Subacute thyroiditis following COVID\u201019 vaccination","volume":"9","author":"Soltanpoor","year":"2021","journal-title":"Clin Case Rep"},{"key":"10.1016\/j.jecr.2022.100138_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.metop.2021.100136","article-title":"Thyroiditis following vaccination against COVID-19: report of two cases and review of the literature","volume":"12","author":"Siolos","year":"2021","journal-title":"Metabolism open"},{"issue":"Supplement_1","key":"10.1016\/j.jecr.2022.100138_bib28","doi-asserted-by":"crossref","first-page":"A956","DOI":"10.1210\/jendso\/bvab048.1953","article-title":"Sub-acute thyroiditis presenting as pyrexia of uknown origin","volume":"5","author":"Bahl","year":"2021","journal-title":"J Endocr. Soc."},{"key":"10.1016\/j.jecr.2022.100138_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.737142","article-title":"Case report: two cases of subacute thyroiditis following SARS-CoV-2 vaccination","volume":"8","author":"Bornemann","year":"2021","journal-title":"Front Med"},{"key":"10.1016\/j.jecr.2022.100138_bib30","article-title":"Can COVID\u201019 immunisation cause subacute thyroiditis?","author":"Ratnayake","year":"2021","journal-title":"Clin Endocrinol"},{"issue":"9","key":"10.1016\/j.jecr.2022.100138_bib31","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1089\/thy.2021.0184","article-title":"Letter to the editor: thyroiditis and thyrotoxicosis after the SARS-CoV-2 mRNA vaccine","volume":"31","author":"Schimmel","year":"2021","journal-title":"Thyroid"},{"issue":"2","key":"10.1016\/j.jecr.2022.100138_bib32","first-page":"9","article-title":"Subacute thyroiditis secondary to moderna COVID-19 vaccine: a case report of a rare manifestation","volume":"1","author":"Patel","year":"2021","journal-title":"Adv Clin Med Res Healthc Deliv"},{"key":"10.1016\/j.jecr.2022.100138_bib33","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/8952048","article-title":"A case report of subacute thyroiditis following mRNA COVID-19 vaccine","author":"Plaza-Enriquez","year":"2021","journal-title":"Case Rep Endocrinol."},{"key":"10.1016\/j.jecr.2022.100138_bib34","doi-asserted-by":"crossref","DOI":"10.1089\/thy.2021.0142","article-title":"Two cases of Graves' disease following SARS-CoV-2 vaccination: an autoimmune\/inflammatory syndrome induced by adjuvants","author":"Vera-Lastra","year":"2021","journal-title":"Thyroid"},{"issue":"3","key":"10.1016\/j.jecr.2022.100138_bib35","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/s12020-021-02898-5","article-title":"Thyrotoxicosis after COVID-19 vaccination: seven case reports and a literature review","volume":"74","author":"Lee","year":"2021","journal-title":"Endocrine"}],"container-title":["Journal of Clinical and Translational Endocrinology: Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214624522000338?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214624522000338?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T14:00:19Z","timestamp":1762005619000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214624522000338"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":35,"alternative-id":["S2214624522000338"],"URL":"https:\/\/doi.org\/10.1016\/j.jecr.2022.100138","relation":{},"ISSN":["2214-6245"],"issn-type":[{"type":"print","value":"2214-6245"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of the immune system and possible mechanisms in COVID-19 vaccine-induced thyroiditis: Case report and literature review","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical and Translational Endocrinology: Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jecr.2022.100138","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100138"}}