{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:35:10Z","timestamp":1791045310067,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009405","name":"Center for the Humanities at Tufts","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009405","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006279","name":"St. Jude Medical","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006279","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Electrocardiology"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.jelectrocard.2018.04.004","type":"journal-article","created":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T02:25:31Z","timestamp":1523499931000},"page":"607-612","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Fragmented QRS complexes after acute myocardial infarction are independently associated with unfavorable left ventricular remodeling"],"prefix":"10.1016","volume":"51","author":[{"given":"Derek S.","family":"Chew","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen B.","family":"Wilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Kavanagh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haris M.","family":"Vaid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle A.","family":"Southern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew G.","family":"Howarth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek V.","family":"Exner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jelectrocard.2018.04.004_bb0005","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1056\/NEJM198308113090602","article-title":"Risk stratification and survival after myocardial infarction","volume":"309","author":"The Multicenter Postinfarction Research Group","year":"1983","journal-title":"N Engl J Med"},{"issue":"25","key":"10.1016\/j.jelectrocard.2018.04.004_bb0010","doi-asserted-by":"crossref","first-page":"3411","DOI":"10.1161\/CIRCULATIONAHA.104.508093","article-title":"Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction","volume":"111","author":"Solomon","year":"2005","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.jelectrocard.2018.04.004_bb0015","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10741-010-9181-7","article-title":"Left ventricular remodeling in the post-infarction heart: a review of cellular, molecular mechanisms, and therapeutic modalities","volume":"16","author":"Gajarsa","year":"2011","journal-title":"Heart Fail Rev"},{"issue":"6","key":"10.1016\/j.jelectrocard.2018.04.004_bb0020","doi-asserted-by":"crossref","first-page":"451","DOI":"10.7326\/0003-4819-134-6-200103200-00009","article-title":"Recovery of ventricular function after myocardial infarction in the reperfusion era: the healing and early afterload reducing therapy study","volume":"134","author":"Solomon","year":"2001","journal-title":"Ann Intern Med"},{"issue":"1","key":"10.1016\/j.jelectrocard.2018.04.004_bb0025","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1161\/CIRCULATIONAHA.107.702993","article-title":"Stunning, hibernation, and assessment of myocardial viability","volume":"117","author":"Camici","year":"2008","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.jelectrocard.2018.04.004_bb0030","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jacc.2007.03.034","article-title":"Evolution of left ventricular ejection fraction and its relationship to infarct size after acute myocardial infarction","volume":"50","author":"Ndrepepa","year":"2007","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"10.1016\/j.jelectrocard.2018.04.004_bb0035","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.116.005461","article-title":"Sudden cardiac death substrate imaged by magnetic resonance imaging: from investigational tool to clinical applications","volume":"10","author":"Wu","year":"2017","journal-title":"Circ Cardiovasc Imaging"},{"issue":"2","key":"10.1016\/j.jelectrocard.2018.04.004_bb0040","first-page":"204","article-title":"Relationship between fragmented QRS and no-reflow, infarct size, and peri-infarct zone assessed using cardiac magnetic resonance in patients with myocardial infarction","volume":"30","author":"Lorgis","year":"2014","journal-title":"Can J Cardiol"},{"issue":"21","key":"10.1016\/j.jelectrocard.2018.04.004_bb0045","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1161\/CIRCULATIONAHA.105.595892","article-title":"Significance of a fragmented QRS complex versus a Q wave in patients with coronary artery disease","volume":"113","author":"Das","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jelectrocard.2018.04.004_bb0050","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ahj.2017.11.014","article-title":"Left ventricular ejection fraction reassessment post-myocardial infarction: current clinical practice and determinants of adverse remodeling","volume":"198","author":"Chew","year":"2018","journal-title":"Am Heart J"},{"issue":"24","key":"10.1016\/j.jelectrocard.2018.04.004_bb0055","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1016\/j.jacc.2007.08.042","article-title":"Noninvasive risk assessment early after a myocardial infarction the REFINE study","volume":"50","author":"Exner","year":"2007","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"10.1016\/j.jelectrocard.2018.04.004_bb0060","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.jacc.2008.12.013","volume":"53","author":"Surawicz","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"22","key":"10.1016\/j.jelectrocard.2018.04.004_bb0065","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1161\/CIRCULATIONAHA.107.187397","article-title":"Universal definition of myocardial infarction","volume":"116","author":"Thygesen","year":"2007","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.jelectrocard.2018.04.004_bb0070","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1161\/CIRCEP.107.763284","article-title":"Fragmented wide QRS on a 12-lead ECG: a sign of myocardial scar and poor prognosis","volume":"1","author":"Das","year":"2008","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"9","key":"10.1016\/j.jelectrocard.2018.04.004_bb0075","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.jcmg.2016.01.033","article-title":"Myocardial fibrosis assessment by LGE is a powerful predictor of ventricular tachyarrhythmias in ischemic and nonischemic LV dysfunction: A Meta-analysis","volume":"9","author":"Disertori","year":"2016","journal-title":"JACC Cardiovasc. Imaging"},{"issue":"2","key":"10.1016\/j.jelectrocard.2018.04.004_bb0080","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jcmg.2010.11.015","article-title":"Evaluation of techniques for the quantification of myocardial scar of differing etiology using cardiac magnetic resonance","volume":"4","author":"Flett","year":"2011","journal-title":"JACC Cardiovasc Imaging"},{"issue":"4","key":"10.1016\/j.jelectrocard.2018.04.004_bb0085","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1161\/CIRCIMAGING.111.971549","article-title":"Prediction of arrhythmic events in ischemic and dilated cardiomyopathy patients referred for implantable cardiac defibrillator: evaluation of multiple scar quantification measures for late gadolinium enhancement magnetic resonance imaging","volume":"5","author":"Gao","year":"2012","journal-title":"Circ Cardiovasc Imaging"},{"issue":"1","key":"10.1016\/j.jelectrocard.2018.04.004_bb0090","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1161\/CIRCULATIONAHA.106.613414","article-title":"Characterization of the peri-infarct zone by contrast-enhanced cardiac magnetic resonance imaging is a powerful predictor of post-myocardial infarction mortality","volume":"114","author":"Yan","year":"2006","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.jelectrocard.2018.04.004_bb0095","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jacc.2007.03.034","article-title":"Evolution of left ventricular ejection fraction and its relationship to infarct size after acute myocardial infarction","volume":"50","author":"Ndrepepa","year":"2007","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.jelectrocard.2018.04.004_bb0100","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.amjcard.2005.03.069","article-title":"Impact and determinants of left ventricular function in patients undergoing primary percutaneous coronary intervention in acute myocardial infarction","volume":"96","author":"Halkin","year":"2005","journal-title":"Am J Cardiol"},{"issue":"23","key":"10.1016\/j.jelectrocard.2018.04.004_bb0105","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1136\/hrt.2009.190819","article-title":"Cardiac troponin I for the prediction of functional recovery and left ventricular remodelling following primary percutaneous coronary intervention for ST-elevation myocardial infarction","volume":"96","author":"Hallen","year":"2010","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.jelectrocard.2018.04.004_bb0110","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1080\/14017430601071849","article-title":"Peak CKMB and cTnT accurately estimates myocardial infarct size after reperfusion","volume":"41","author":"Hedstrom","year":"2007","journal-title":"Scandinavian Cardiovascular Journal: SCJ"},{"issue":"1","key":"10.1016\/j.jelectrocard.2018.04.004_bb0115","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.hrthm.2009.09.065","article-title":"Fragmented QRS on twelve-lead electrocardiogram predicts arrhythmic events in patients with ischemic and nonischemic cardiomyopathy","volume":"7","author":"Das","year":"2010","journal-title":"Heart Rhythm"},{"issue":"24","key":"10.1016\/j.jelectrocard.2018.04.004_bb0120","doi-asserted-by":"crossref","first-page":"2762","DOI":"10.1016\/j.jacc.2010.01.052","article-title":"Quantitative tissue characterization of infarct core and border zone in patients with ischemic cardiomyopathy by magnetic resonance is associated with future cardiovascular events","volume":"55","author":"Heidary","year":"2010","journal-title":"J Am Coll Cardiol"},{"issue":"9","key":"10.1016\/j.jelectrocard.2018.04.004_bb0125","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.jcmg.2015.12.025","article-title":"The fault is in our scars: LGE and ventricular arrhythmia risk in LV dysfunction","volume":"9","author":"Bilchick","year":"2016","journal-title":"JACC Cardiovasc Imaging"},{"issue":"4","key":"10.1016\/j.jelectrocard.2018.04.004_bb0130","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.ahj.2013.07.019","volume":"166","author":"Miller","year":"2013","journal-title":"Am Heart J"}],"container-title":["Journal of Electrocardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022073618300980?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022073618300980?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T19:50:27Z","timestamp":1762199427000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022073618300980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["S0022073618300980"],"URL":"https:\/\/doi.org\/10.1016\/j.jelectrocard.2018.04.004","relation":{},"ISSN":["0022-0736"],"issn-type":[{"value":"0022-0736","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fragmented QRS complexes after acute myocardial infarction are independently associated with unfavorable left ventricular remodeling","name":"articletitle","label":"Article Title"},{"value":"Journal of Electrocardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jelectrocard.2018.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}