{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T05:30:25Z","timestamp":1772861425651,"version":"3.50.1"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002403","name":"Taibah University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002403","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Electrocardiology"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.jelectrocard.2023.09.012","type":"journal-article","created":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T11:06:54Z","timestamp":1696676814000},"page":"218-223","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Personalized, intuitive & visual QT-prolongation monitoring using patient-specific QTc threshold with pseudo-coloring and explainable AI"],"prefix":"10.1016","volume":"81","author":[{"given":"Alaa","family":"Alahmadi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Davies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markel","family":"Vigo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Jay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jelectrocard.2023.09.012_bb0005","series-title":"Acquired long QT syndrome","author":"Camm","year":"2008"},{"issue":"4","key":"10.1016\/j.jelectrocard.2023.09.012_bb0010","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1177\/00912709922007912","article-title":"Assessment of QTc prolongation for non-cardiac-related drugs from a drug development perspective","volume":"39","author":"Bonate","year":"1999","journal-title":"J Clin Pharmacol"},{"issue":"20","key":"10.1016\/j.jelectrocard.2023.09.012_bb0015","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.2174\/1381612043383872","article-title":"Cardiovascular side effects of new antidepressants and antipsychotics: new drugs, old concerns?","volume":"0","author":"Pacher","year":"2004","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.jelectrocard.2023.09.012_bb0020","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.jacc.2017.07.723","article-title":"Computer-interpreted electrocardiograms: benefits and limitations","author":"Schlapfer","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jelectrocard.2023.09.012_bb0025","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1080\/AC.70.2.3073513","article-title":"Underestimated and unreported prolonged QTc by automated ECG analysis in patients on methadone: can we rely on computer reading?","author":"Talebi","year":"2015","journal-title":"Acta Cardiol"},{"issue":"11","key":"10.1016\/j.jelectrocard.2023.09.012_bb0030","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1016\/j.hrthm.2015.06.040","article-title":"Diagnostic value of T-wave morphology changes during \u201cQT stretching\u201d in patients with long QT syndrome","volume":"12","author":"Chorin","year":"2015","journal-title":"Heart Rhythm"},{"issue":"2","key":"10.1016\/j.jelectrocard.2023.09.012_bb0035","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jacc.2009.03.043","article-title":"Giant T\u2013U waves precede torsades de pointes in long QT syndrome: a systematic electrocardiographic analysis in patients with acquired and congenital QT prolongation","volume":"54","author":"Kirchhof","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"10.1016\/j.jelectrocard.2023.09.012_bb0040","doi-asserted-by":"crossref","first-page":"e241","DOI":"10.1161\/CIRCULATIONAHA.108.191096","article-title":"AHA\/ACCF\/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association electrocardiography and arrhythmias C","volume":"119","author":"Rautaharju","year":"2009","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.jelectrocard.2023.09.012_bb0045","first-page":"609","article-title":"Drug-induced QT prolongation and torsades de pointes: evaluation of a QT nomogram","volume":"100","author":"Chan","year":"2007","journal-title":"Int J Med"},{"key":"10.1016\/j.jelectrocard.2023.09.012_bb0050","series-title":"CHI conference on human factors in computing systems, Glasgow","article-title":"Evaluating the impact of pseudo-colour and coordinate system on the detection of medication-induced ECG changes","author":"Alahmadi","year":"2019"},{"key":"10.1016\/j.jelectrocard.2023.09.012_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.compbiomed.2021.104281","article-title":"An explainable algorithm for detecting drug-induced QT-prolongation at risk of torsades de pointes (TdP) regardless of heart rate and T-wave morphology","volume":"131","author":"Alahmadi","year":"2021","journal-title":"Comput Biol Med"},{"issue":"20","key":"10.1016\/j.jelectrocard.2023.09.012_bb0060","article-title":"Pseudo-colouring an ECG enables lay people to detect QT-interval prolongation regardless of heart rate","volume":"15","author":"Alahmadi","year":"2020","journal-title":"PloS One"},{"key":"10.1016\/j.jelectrocard.2023.09.012_bb0065","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/nrd1108","article-title":"The impact of drug-induced QT interval prolongation on drug discovery and development","volume":"2","author":"Fermini","year":"2003","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.jelectrocard.2023.09.012_bb0070","series-title":"European Agency for the Evaluation of Medicinal Products. Human Medicines Evaluation Unit","article-title":"Points to consider: The assessment of the potential for QT interval prolongation by noncardiovascular medicinal products","author":"CPMP","year":"1997"},{"issue":"5","key":"10.1016\/j.jelectrocard.2023.09.012_bb0075","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/clpt.2014.155","article-title":"Differentiating drug- induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranola- zine, and verapamil","volume":"96","author":"Johannesen","year":"2014","journal-title":"Clin Pharmacol Therap"},{"issue":"23","key":"10.1016\/j.jelectrocard.2023.09.012_bb0080","doi-asserted-by":"crossref","first-page":"e215","DOI":"10.1161\/01.CIR.101.23.e215","article-title":"PhysioBank, physio- toolkit, and PhysioNet: components of a new research resource for complex physiologic signals","volume":"101","author":"Goldberger","year":"2000","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.jelectrocard.2023.09.012_bb0085","article-title":"The advantages of the Matthews correlation coefficient (MCC) over f1 score and accuracy in binary classification evaluation","volume":"21","author":"C. D., J. G. and G. BMC","year":"2020","journal-title":"BMC Genomics"},{"issue":"11","key":"10.1016\/j.jelectrocard.2023.09.012_bb0090","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1136\/heart.89.11.1363","article-title":"Drug induced QT prolongation and torsades de pointes","volume":"89","author":"Yap","year":"2003","journal-title":"Heart"},{"key":"10.1016\/j.jelectrocard.2023.09.012_bb0095","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1176\/appi.psy.45.5.371","article-title":"Tricyclic antidepressants, QT interval prolongation, and torsade de pointes","author":"Vieweg","year":"2004","journal-title":"Psychosomatics"},{"issue":"2","key":"10.1016\/j.jelectrocard.2023.09.012_bb0100","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.pharmthera.2008.03.005","article-title":"Drugs for men and women\u2014how important is gender as a risk factor for TdP?","volume":"119","author":"Coker","year":"2008","journal-title":"Pharmacol Ther"}],"container-title":["Journal of Electrocardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022073623002224?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022073623002224?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T12:36:38Z","timestamp":1758285398000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022073623002224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":20,"alternative-id":["S0022073623002224"],"URL":"https:\/\/doi.org\/10.1016\/j.jelectrocard.2023.09.012","relation":{},"ISSN":["0022-0736"],"issn-type":[{"value":"0022-0736","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Personalized, intuitive & visual QT-prolongation monitoring using patient-specific QTc threshold with pseudo-coloring and explainable AI","name":"articletitle","label":"Article Title"},{"value":"Journal of Electrocardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jelectrocard.2023.09.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}