{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:42:02Z","timestamp":1786992122275,"version":"build-2736575974"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"am","delay-in-days":351,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL158022"],"award-info":[{"award-number":["R01 HL158022"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K24HL155813"],"award-info":[{"award-number":["K24HL155813"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["75N92022D00003"],"award-info":[{"award-number":["75N92022D00003"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["75N92022D00005"],"award-info":[{"award-number":["75N92022D00005"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL141288"],"award-info":[{"award-number":["R01HL141288"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["RF1 NS127266"],"award-info":[{"award-number":["RF1 NS127266"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["75N92022D00004"],"award-info":[{"award-number":["75N92022D00004"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL126637"],"award-info":[{"award-number":["R01HL126637"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["75N92022D00001"],"award-info":[{"award-number":["75N92022D00001"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["75N92022D00002"],"award-info":[{"award-number":["75N92022D00002"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AG075883"],"award-info":[{"award-number":["R01AG075883"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Electrocardiology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.jelectrocard.2024.03.016","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T01:34:14Z","timestamp":1713317654000},"page":"123-128","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Deep terminal negative of the P wave in V1 and incidence of ischemic stroke: The atherosclerosis risk in communities (ARIC) study"],"prefix":"10.1016","volume":"84","author":[{"given":"Mingfang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuekai","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youmei","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamakshi","family":"Lakshminarayan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsayed Z.","family":"Soliman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minglong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin Yee","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jelectrocard.2024.03.016_bb0005","first-page":"279","article-title":"Stroke prevention in atrial fibrillation","volume":"3","author":"Katsnelson","year":"2010","journal-title":"J Atr Fibrillation"},{"issue":"4","key":"10.1016\/j.jelectrocard.2024.03.016_bb0010","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1161\/CIRCULATIONAHA.115.016795","article-title":"Evaluating the atrial myopathy underlying atrial fibrillation: identifying the Arrhythmogenic and Thrombogenic substrate","volume":"132","author":"Goldberger","year":"2015","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.jelectrocard.2024.03.016_bb0015","volume":"15","author":"Chen","year":"2022","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"7","key":"10.1016\/j.jelectrocard.2024.03.016_bb0020","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/S0002-9149(77)80209-9","article-title":"Electrocardiographic left atrial enlargement. Electrophysiologic, echocardiographic and hemodynamic correlates","volume":"39","author":"Josephson","year":"1977","journal-title":"Am J Cardiol"},{"issue":"6","key":"10.1016\/j.jelectrocard.2024.03.016_bb0025","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.114.001387","article-title":"Electrocardiographic deep terminal negativity of the P wave in V(1) and risk of sudden cardiac death: the atherosclerosis risk in communities (ARIC) study","volume":"3","author":"Tereshchenko","year":"2014","journal-title":"J Am Heart Assoc"},{"issue":"4","key":"10.1016\/j.jelectrocard.2024.03.016_bb0030","doi-asserted-by":"crossref","DOI":"10.1111\/anec.12969","article-title":"Deep terminal negativity of the P-wave in V1 and stroke risk: the National Health and nutrition examination survey III","volume":"27","author":"Shen","year":"2022","journal-title":"Ann Noninvasive Electrocardiol"},{"issue":"6","key":"10.1016\/j.jelectrocard.2024.03.016_bb0035","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1177\/1747493019876543","article-title":"Atrial cardiopathy and stroke mortality in the general population","volume":"15","author":"Ahmad","year":"2020","journal-title":"Int J Stroke"},{"issue":"23","key":"10.1016\/j.jelectrocard.2024.03.016_bb0040","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1016\/j.jacc.2021.04.035","article-title":"The ARIC (atherosclerosis risk in communities) study: JACC focus seminar 3\/8","volume":"77","author":"Wright","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jelectrocard.2024.03.016_bb0045","volume":"12(2 Pt 2 Suppl 1):I1-91","year":"1981","journal-title":"Stroke"},{"issue":"4","key":"10.1016\/j.jelectrocard.2024.03.016_bb0050","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1161\/01.STR.30.4.736","article-title":"Stroke incidence and survival among middle-aged adults: 9-year follow-up of the atherosclerosis risk in communities (ARIC) cohort","volume":"30","author":"Rosamond","year":"1999","journal-title":"Stroke"},{"issue":"2","key":"10.1016\/j.jelectrocard.2024.03.016_bb0055","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0895-4356(95)00041-0","article-title":"Community surveillance of coronary heart disease in the atherosclerosis risk in communities (ARIC) study: methods and initial two years\u2019 experience","volume":"49","author":"White","year":"1996","journal-title":"J Clin Epidemiol"},{"issue":"7","key":"10.1016\/j.jelectrocard.2024.03.016_bb0060","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.amjcard.2007.11.061","article-title":"Heart failure incidence and survival (from the atherosclerosis risk in communities study)","volume":"101","author":"Loehr","year":"2008","journal-title":"Am J Cardiol"},{"issue":"4","key":"10.1016\/j.jelectrocard.2024.03.016_bb0065","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.ahj.2009.12.035","article-title":"Diagnostic and prognostic utility of electrocardiography for left ventricular hypertrophy defined by magnetic resonance imaging in relationship to ethnicity: the multi-ethnic study of atherosclerosis (MESA)","volume":"159","author":"Jain","year":"2010","journal-title":"Am Heart J"},{"issue":"1","key":"10.1016\/j.jelectrocard.2024.03.016_bb0070","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ahj.2009.05.010","article-title":"Incidence of atrial fibrillation in whites and African-Americans: the atherosclerosis risk in communities (ARIC) study","volume":"158","author":"Alonso","year":"2009","journal-title":"Am Heart J"},{"issue":"2","key":"10.1016\/j.jelectrocard.2024.03.016_bb0075","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.115.004010","article-title":"Left atrial structure and function across the Spectrum of cardiovascular risk in the elderly: the atherosclerosis risk in communities study","volume":"9","author":"Goncalves","year":"2016","journal-title":"Circ Cardiovasc Imaging"},{"issue":"1","key":"10.1016\/j.jelectrocard.2024.03.016_bb0080","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1161\/CIRCIMAGING.113.000736","article-title":"Rationale and design of a multicenter echocardiographic study to assess the relationship between cardiac structure and function and heart failure risk in a biracial cohort of community-dwelling elderly persons: the atherosclerosis risk in communities study","volume":"7","author":"Shah","year":"2014","journal-title":"Circ Cardiovasc Imaging"},{"issue":"2","key":"10.1016\/j.jelectrocard.2024.03.016_bb0085","doi-asserted-by":"crossref","DOI":"10.1002\/sim.2929","article-title":"Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond","volume":"27","author":"Pencina","year":"2008","journal-title":"Stat Med"},{"issue":"4","key":"10.1016\/j.jelectrocard.2024.03.016_bb0090","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1212\/WNL.0000000000002888","article-title":"Advanced interatrial block and ischemic stroke: the atherosclerosis risk in communities study","volume":"87","author":"O\u2019Neal","year":"2016","journal-title":"Neurology"},{"issue":"8","key":"10.1016\/j.jelectrocard.2024.03.016_bb0095","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1161\/STROKEAHA.117.017226","article-title":"Abnormal P-wave Axis and ischemic stroke: the ARIC study (atherosclerosis risk in communities)","volume":"48","author":"Maheshwari","year":"2017","journal-title":"Stroke"},{"issue":"7","key":"10.1016\/j.jelectrocard.2024.03.016_bb0100","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1093\/europace\/euaa114","article-title":"Advanced interatrial block and P-wave duration are associated with atrial fibrillation and stroke in older adults with heart disease: the BAYES registry","volume":"22","author":"Martinez-Selles","year":"2020","journal-title":"Europace"},{"issue":"9","key":"10.1016\/j.jelectrocard.2024.03.016_bb0105","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1016\/j.hrthm.2015.04.026","article-title":"P-wave duration and the risk of atrial fibrillation: results from the Copenhagen ECG study","volume":"12","author":"Nielsen","year":"2015","journal-title":"Heart Rhythm"},{"issue":"3","key":"10.1016\/j.jelectrocard.2024.03.016_bb0110","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1161\/STROKEAHA.114.007762","article-title":"Association between left atrial abnormality on ECG and vascular brain injury on MRI in the cardiovascular health study","volume":"46","author":"Kamel","year":"2015","journal-title":"Stroke"},{"issue":"5","key":"10.1016\/j.jelectrocard.2024.03.016_bb0115","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1002\/ana.24482","article-title":"Electrocardiographic left atrial abnormality and stroke subtype in the atherosclerosis risk in communities study","volume":"78","author":"Kamel","year":"2015","journal-title":"Ann Neurol"},{"issue":"9","key":"10.1016\/j.jelectrocard.2024.03.016_bb0120","doi-asserted-by":"crossref","first-page":"2786","DOI":"10.1161\/STROKEAHA.114.006364","article-title":"P-wave morphology and the risk of incident ischemic stroke in the multi-ethnic study of atherosclerosis","volume":"45","author":"Kamel","year":"2014","journal-title":"Stroke"},{"issue":"2","key":"10.1016\/j.jelectrocard.2024.03.016_bb0125","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1161\/CIRCULATIONAHA.118.035411","article-title":"Refining prediction of atrial fibrillation-related stroke using the P(2)-CHA(2)DS(2)-VASc score","volume":"139","author":"Maheshwari","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.jelectrocard.2024.03.016_bb0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jelectrocard.2019.07.005","article-title":"Advanced interatrial block: an electrocardiographic marker for stroke recurrence","volume":"57","author":"Garcia-Talavera","year":"2019","journal-title":"J Electrocardiol"},{"issue":"8","key":"10.1016\/j.jelectrocard.2024.03.016_bb0135","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1161\/STROKEAHA.117.017293","article-title":"P-wave indices and risk of ischemic stroke: a systematic review and Meta-analysis","volume":"48","author":"He","year":"2017","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.jelectrocard.2024.03.016_bb0140","doi-asserted-by":"crossref","first-page":"39","DOI":"10.7326\/M22-1638","article-title":"Left atrial mechanical dysfunction and the risk for ischemic stroke in people without prevalent atrial fibrillation or stroke\u202f: a prospective cohort study","volume":"176","author":"Maheshwari","year":"2023","journal-title":"Ann Intern Med"},{"issue":"3","key":"10.1016\/j.jelectrocard.2024.03.016_bb0145","doi-asserted-by":"crossref","first-page":"323","DOI":"10.2217\/fca.15.22","article-title":"Atrial cardiopathy: a broadened concept of left atrial thromboembolism beyond atrial fibrillation","volume":"11","author":"Kamel","year":"2015","journal-title":"Future Cardiol"},{"issue":"1","key":"10.1016\/j.jelectrocard.2024.03.016_bb0150","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1016\/j.hrthm.2016.05.028","article-title":"EHRA\/HRS\/APHRS\/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication","volume":"14","author":"Goette","year":"2017","journal-title":"Heart Rhythm"},{"issue":"3","key":"10.1016\/j.jelectrocard.2024.03.016_bb0155","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jacep.2019.12.013","article-title":"The atrium and embolic stroke: myopathy not atrial fibrillation as the requisite determinant?","volume":"6","author":"Sajeev","year":"2020","journal-title":"JACC Clin Electrophysiol"},{"issue":"7","key":"10.1016\/j.jelectrocard.2024.03.016_bb0160","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1001\/jama.2023.27188","article-title":"Apixaban to prevent recurrence after cryptogenic stroke in patients with atrial Cardiopathy: the ARCADIA randomized clinical trial","volume":"331","author":"Kamel","year":"2024","journal-title":"JAMA"},{"issue":"19","key":"10.1016\/j.jelectrocard.2024.03.016_bb0165","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1136\/heartjnl-2013-305303","article-title":"Prediction of stroke or TIA in patients without atrial fibrillation using CHADS2 and CHA2DS2-VASc scores","volume":"100","author":"Mitchell","year":"2014","journal-title":"Heart"}],"container-title":["Journal of Electrocardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022073624000517?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022073624000517?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T18:48:37Z","timestamp":1718218117000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022073624000517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":33,"alternative-id":["S0022073624000517"],"URL":"https:\/\/doi.org\/10.1016\/j.jelectrocard.2024.03.016","relation":{},"ISSN":["0022-0736"],"issn-type":[{"value":"0022-0736","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deep terminal negative of the P wave in V1 and incidence of ischemic stroke: The atherosclerosis risk in communities (ARIC) study","name":"articletitle","label":"Article Title"},{"value":"Journal of Electrocardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jelectrocard.2024.03.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}