{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T06:52:40Z","timestamp":1780469560730,"version":"3.54.1"},"reference-count":16,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jem-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Emergency Medicine"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.jemermed.2015.06.020","type":"journal-article","created":{"date-parts":[[2015,8,15]],"date-time":"2015-08-15T15:01:48Z","timestamp":1439650908000},"page":"482-484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hypovolemia Resulting in Platypnea-Orthodeoxia Syndrome"],"prefix":"10.1016","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9891-684X","authenticated-orcid":false,"given":"Stephen","family":"Ducey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7686-361X","authenticated-orcid":false,"given":"Jeffrey","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jemermed.2015.06.020_bib1","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.ajem.2013.06.043","article-title":"A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial","volume":"31","author":"Zahed","year":"2013","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.jemermed.2015.06.020_bib2","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1053\/euhj.1999.1944","article-title":"Atrial right-to-left shunting causing severe hypoxaemia despite normal right-sided pressures. Report of 11 consecutive cases corrected by percutaneous closure","volume":"21","author":"Godart","year":"2000","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jemermed.2015.06.020_bib3","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1002\/clc.22301","article-title":"Cardiac platypnea-orthodeoxia syndrome: an often unrecognized malady","volume":"37","author":"Knapper","year":"2014","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.jemermed.2015.06.020_bib4","first-page":"2599","article-title":"The platypnea-orthodeoxia syndrome","volume":"18","author":"Akin","year":"2014","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.jemermed.2015.06.020_bib5","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1161\/circ.105.6.e47","article-title":"Mechanisms of platypnea-orthodeoxia: what causes water to flow uphill?","volume":"105","author":"Cheng","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jemermed.2015.06.020_bib6","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1378\/chest.112.6.1449","article-title":"An analysis of platypnea-orthodeoxia syndrome including a \u201cnew\u201d therapeutic approach","volume":"112","author":"Robin","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.jemermed.2015.06.020_bib7","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1378\/chest.112.6.1682","article-title":"Platypnea-orthodeoxia related to aortic elongation","volume":"112","author":"Popp","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.jemermed.2015.06.020_bib8","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1378\/chest.118.3.871","article-title":"A case of orthodeoxia caused by an atrial septal aneurysm","volume":"118","author":"Acharya","year":"2000","journal-title":"Chest"},{"key":"10.1016\/j.jemermed.2015.06.020_bib9","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1016\/j.athoracsur.2009.08.050","article-title":"Platypnea-orthodeoxia diagnosed by sitting transesophageal echocardiography","volume":"89","author":"Nakahira","year":"2010","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jemermed.2015.06.020_bib10","first-page":"219","article-title":"Identification of a prominent eustachian valve by means of contrast two-dimensional echocardiography","volume":"10","author":"Leon","year":"1983","journal-title":"Tex Heart Inst J"},{"key":"10.1016\/j.jemermed.2015.06.020_bib11","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.ejim.2013.08.698","article-title":"Platypnea-orthodeoxia syndrome in the elderly treated by percutaneous patent foramen ovale closure: a case series and literature review","volume":"24","author":"Blanche","year":"2013","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.jemermed.2015.06.020_bib12","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1056\/NEJM196912112812408","article-title":"Platypnea (diffuse zone I phenomenon?)","volume":"281","author":"Altman","year":"1969","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jemermed.2015.06.020_bib13","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1540-8175.2008.00780.x","article-title":"Platypnea-orthodeoxia syndrome associated with patent foramen ovale and aortic ectasia","volume":"26","author":"Kusunose","year":"2009","journal-title":"Echocardiography"},{"key":"10.1016\/j.jemermed.2015.06.020_bib14","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1097\/SMJ.0b013e3181b35f0f","article-title":"Platypnea-orthodeoxia syndrome: a diagnostic challenge","volume":"102","author":"Desouza","year":"2009","journal-title":"South Med J"},{"key":"10.1016\/j.jemermed.2015.06.020_bib15","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s00270-004-0035-3","article-title":"Transcatheter closure of patent foramen ovale in patients with platypnea-orthodeoxia: results of a multicentric French registry","volume":"28","author":"Gu\u00e9rin","year":"2005","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jemermed.2015.06.020_bib16","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3109\/14017437809100362","article-title":"Platypnoea after pneumonectomy caused by a combination of intracardiac right-to-left shunt and hypovolaemia. Relief of symptoms on restitution of blood volume","volume":"12","author":"Wranne","year":"1978","journal-title":"Scand J Thorac Cardiovasc Surg"}],"container-title":["The Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0736467915006289?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0736467915006289?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:34:24Z","timestamp":1760027664000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0736467915006289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S0736467915006289"],"URL":"https:\/\/doi.org\/10.1016\/j.jemermed.2015.06.020","relation":{},"ISSN":["0736-4679"],"issn-type":[{"value":"0736-4679","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypovolemia Resulting in Platypnea-Orthodeoxia Syndrome","name":"articletitle","label":"Article Title"},{"value":"The Journal of Emergency Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jemermed.2015.06.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}