{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T17:45:39Z","timestamp":1784396739545,"version":"3.55.0"},"reference-count":152,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["BT\/IN\/Indo-UK\/AMR-Envi\/05\/NT\/2020-21"],"award-info":[{"award-number":["BT\/IN\/Indo-UK\/AMR-Envi\/05\/NT\/2020-21"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000312","name":"Joseph Rowntree Foundation","doi-asserted-by":"publisher","award":["BT\/IN\/Indo-UK\/AMR-Envi\/05\/NT\/2020-21"],"award-info":[{"award-number":["BT\/IN\/Indo-UK\/AMR-Envi\/05\/NT\/2020-21"]}],"id":[{"id":"10.13039\/501100000312","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Environmental Management"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.jenvman.2021.113315","type":"journal-article","created":{"date-parts":[[2021,7,20]],"date-time":"2021-07-20T20:24:14Z","timestamp":1626812654000},"page":"113315","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"special_numbering":"C","title":["Mobility of antibiotic resistance and its co-occurrence with metal resistance in pathogens under oxidative stress"],"prefix":"10.1016","volume":"297","author":[{"given":"Sakina","family":"Bombaywala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemant J.","family":"Purohit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishant A.","family":"Dafale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jenvman.2021.113315_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/antibiotics9060302","article-title":"Proteomic characterization of antibiotic resistance, and production of antimicrobial and virulence factors in streptococcus species associated with bovine mastitis. Could enzybiotics represent novel therapeutic agents against these pathogens?","volume":"9","author":"Abril","year":"2020","journal-title":"Antibiotics"},{"key":"10.1016\/j.jenvman.2021.113315_bib2","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1007\/s00248-014-0409-2","article-title":"Plasmid-related quinolone resistance determinants in epidemic Vibrio parahaemolyticus, uropathogenic Escherichia coli, and marine bacteria from an aquaculture area in Chile","volume":"68","author":"Aedo","year":"2014","journal-title":"Microb. Ecol."},{"key":"10.1016\/j.jenvman.2021.113315_bib3","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1574-6968.2011.02453.x","article-title":"Sublethal ciprofloxacin treatment leads to resistance via antioxidant systems in Proteus mirabilis","volume":"327","author":"Aiassa","year":"2012","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.jenvman.2021.113315_bib4","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1080\/14787210.2019.1614914","article-title":"Recent advances in antibacterial applications of metal nanoparticles (MNPs) and metal nanocomposites (MNCs) against multidrug-resistant (MDR) bacteria","volume":"17","author":"Alavi","year":"2019","journal-title":"Expert Rev. Anti Infect. Ther."},{"issue":"513","key":"10.1016\/j.jenvman.2021.113315_bib5","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.scitotenv.2015.01.046","article-title":"Microbiological characterization of aquatic microbiomes targeting taxonomical marker genes and antibiotic resistance genes of opportunistic bacteria","volume":"512","author":"Alexander","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jenvman.2021.113315_bib6","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/ismej.2008.86","article-title":"Functional metagenomics reveals diverse \u0392-lactamases in a remote Alaskan soil","volume":"3","author":"Allen","year":"2009","journal-title":"ISME J."},{"key":"10.1016\/j.jenvman.2021.113315_bib7","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nrmicro2312","article-title":"Call of the wild: antibiotic resistance genes in natural environments","volume":"8","author":"Allen","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1462-2920.2001.00161.x","article-title":"Environmental selection of antibiotic resistance genes","volume":"3","author":"Alonso","year":"2001","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib9","first-page":"26","article-title":"Antibiotic resistance in wastewater: occurrence and fate of Enterobacteriaceae producers of class A and class C \u03b2-lactamases","volume":"50","author":"Amador","year":"2015","journal-title":"J. Environ. Sci. Heal. - Part A Toxic\/Hazardous Subst. Environ. Eng."},{"key":"10.1016\/j.jenvman.2021.113315_bib10","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/nrmicro3270","article-title":"Microbiological effects of sublethal levels of antibiotics","volume":"12","author":"Andersson","year":"2014","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib11","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1128\/MMBR.00034-07","article-title":"Fe-S cluster Assembly pathways in bacteria","volume":"72","author":"Ayala-Castro","year":"2008","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.jenvman.2021.113315_bib12","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.tim.2006.02.006","article-title":"Co-selection of antibiotic and metal resistance","volume":"14","author":"Baker-Austin","year":"2006","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2015.01216","article-title":"The role of biofilms as environmental reservoirs of antibiotic resistance","volume":"6","author":"Balc\u00e1zar","year":"2015","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib14","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.scitotenv.2016.06.228","article-title":"Elucidating selection processes for antibiotic resistance in sewage treatment plants using metagenomics","volume":"572","author":"Bengtsson-Palme","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jenvman.2021.113315_bib15","doi-asserted-by":"crossref","first-page":"2795","DOI":"10.1128\/AAC.00156-11","article-title":"In vitro selection of ramR and soxR mutants overexpressing efflux systems by fluoroquinolones as well as cefoxitin in Klebsiella pneumoniae","volume":"55","author":"Bialek-Davenet","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3390\/microorganisms4010014","article-title":"Bacterial multidrug efflux pumps: much more than antibiotic resistance determinants","volume":"4","author":"Blanco","year":"2016","journal-title":"Microorganisms"},{"key":"10.1016\/j.jenvman.2021.113315_bib17","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1365-2672.2008.03765.x","article-title":"Multiresistant waterborne pathogens isolated from water reservoirs and cooling systems","volume":"105","author":"Blasco","year":"2008","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib18","doi-asserted-by":"crossref","first-page":"10780","DOI":"10.1007\/s11356-020-11318-6","article-title":"Study of indiscriminate distribution of restrained antimicrobial resistome of different environmental niches","volume":"28","author":"Bombaywala","year":"2021","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2013.01.016","article-title":"Detection and fate of antibiotic resistant bacteria in wastewater treatment plants: a review","author":"Bouki","year":"2013","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jenvman.2021.113315_bib20","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.2741\/1232","article-title":"Iron uptake by E.coli","volume":"8","author":"Braun","year":"2003","journal-title":"Front. Biosci."},{"key":"10.1016\/j.jenvman.2021.113315_bib21","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/S0140-6736(05)78210-6","article-title":"Limitation of Acinetobacter baumannii treatment by plasmid-mediated carbapenemase ARI-2","volume":"351","author":"Brown","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.jenvman.2021.113315_bib22","doi-asserted-by":"crossref","first-page":"3605","DOI":"10.1128\/AAC.00058-10","article-title":"Cloning and occurrence of czrC, a gene conferring cadmium and zinc resistance in methicillin-resistant Staphylococcus aureus CC398 isolates","volume":"54","author":"Cavaco","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib23","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s10653-010-9325-7","article-title":"A review of the distribution of particulate trace elements in urban terrestrial environments and its application to considerations of risk","volume":"33","author":"Charlesworth","year":"2011","journal-title":"Environ. Geochem. Health"},{"key":"10.1016\/j.jenvman.2021.113315_bib24","doi-asserted-by":"crossref","first-page":"12753","DOI":"10.1021\/es403818e","article-title":"Metagenomic profiles of antibiotic resistance genes (ARGs) between human impacted estuary and deep ocean sediments","volume":"47","author":"Chen","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jenvman.2021.113315_bib25","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jhazmat.2014.06.010","article-title":"The role of class I integrons in the dissemination of sulfonamide resistance genes in the Pearl River and Pearl River Estuary, South China","volume":"282","author":"Chen","year":"2015","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.jenvman.2021.113315_bib26","doi-asserted-by":"crossref","first-page":"6670","DOI":"10.1021\/acs.est.6b00619","article-title":"Metagenomic analysis revealing antibiotic resistance genes (ARGs) and their genetic compartments in the Tibetan environment","volume":"50","author":"Chen","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jenvman.2021.113315_bib27","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.watres.2018.11.019","article-title":"Antibiotic-resistance gene transfer in antibiotic-resistance bacteria under different light irradiation: implications from oxidative stress and gene expression","volume":"149","author":"Chen","year":"2019","journal-title":"Water Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib28","first-page":"2691","article-title":"Detected together in strains of both Escherichia coli and Enterococcus faecium","volume":"45","author":"Chow","year":"2001","journal-title":"Society"},{"key":"10.1016\/j.jenvman.2021.113315_bib29","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1186\/s12859-018-2336-6","article-title":"Rapid and precise alignment of raw reads against redundant databases with KMA","volume":"19","author":"Clausen","year":"2018","journal-title":"BMC Bioinf."},{"key":"10.1016\/j.jenvman.2021.113315_bib30","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1021\/es1029206","article-title":"Broad dissemination of plasmid-mediated quinolone resistance genes in sediments of two urban coastal wetlands","volume":"45","author":"Cummings","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jenvman.2021.113315_bib31","article-title":"Genomic tools for the impact assessment of \u2018hotspots\u2019 for early warning of MDR threats","author":"Dafale","year":"2016","journal-title":"Biomed. Environ. Sci."},{"key":"10.1016\/j.jenvman.2021.113315_bib32","doi-asserted-by":"crossref","DOI":"10.1007\/s12088-020-00860-z","article-title":"Zoonosis: an emerging link to antibiotic resistance under \u201cone health approach","author":"Dafale","year":"2020","journal-title":"Indian J. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib33","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1126\/science.1155157","article-title":"Bacteria subsisting on antibiotics","volume":"320","author":"Dantas","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.jenvman.2021.113315_bib34","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.anaerobe.2014.01.008","article-title":"Methanogenic archaea diversity in Hanwoo (Bos taurus coreanae) rumen fluid, rectal dung, and barn floor manure using a culture-independent method based on mcrA gene sequences","volume":"27","author":"Daquiado","year":"2014","journal-title":"Anaerobe"},{"key":"10.1016\/j.jenvman.2021.113315_bib35","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1399-302X.2005.00218.x","article-title":"Isolation of silver- and antibiotic-resistant Enterobacter cloacae from teeth","volume":"20","author":"Davis","year":"2005","journal-title":"Oral Microbiol. Immunol."},{"key":"10.1016\/j.jenvman.2021.113315_bib36","doi-asserted-by":"crossref","DOI":"10.1038\/nature10388","article-title":"Antibiotic resistance is ancient","author":"Dcosta","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.jenvman.2021.113315_bib37","doi-asserted-by":"crossref","first-page":"6528","DOI":"10.1021\/acs.est.5b01031","article-title":"Accumulation of clinically relevant antibiotic-resistance genes, bacterial load, and metals in freshwater lake sediments in central europe","volume":"49","author":"Devarajan","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jenvman.2021.113315_bib38","doi-asserted-by":"crossref","first-page":"4396","DOI":"10.1128\/AEM.01763-09","article-title":"Metagenomic analysis of apple orchard soil reveals antibiotic resistance genes encoding predicted bifunctional proteins","volume":"76","author":"Donato","year":"2010","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib39","doi-asserted-by":"crossref","DOI":"10.1038\/msb4100135","article-title":"Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli","volume":"3","author":"Dwyer","year":"2007","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.jenvman.2021.113315_bib40","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.mib.2009.06.018","article-title":"Role of reactive oxygen species in antibiotic action and resistance","volume":"12","author":"Dwyer","year":"2009","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib41","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1128\/AAC.00944-09","article-title":"Constitutive SoxS expression in a fluoroquinolone-resistant strain with a truncated SoxR protein and identification of a new member of the marA-soxS-rob regulon, mdtG","volume":"54","author":"F\u00e0brega","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib42","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.vetmic.2015.09.001","article-title":"Comparative genome analysis of IncHI 2 VIM-1 carbapenemase-encoding plasmids of Escherichia coli and Salmonella enterica isolated from a livestock farm in Germany","volume":"200","author":"Falgenhauer","year":"2017","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib43","doi-asserted-by":"crossref","first-page":"5599","DOI":"10.1016\/j.watres.2011.08.021","article-title":"Diversity and antibiotic resistance of Aeromonas spp. in drinking and waste water treatment plants","volume":"45","author":"Figueira","year":"2011","journal-title":"Water Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib44","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1126\/science.1220761","article-title":"The shared antibiotic resistome of soil bacteria and human pathogens","volume":"337","author":"Forsberg","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.jenvman.2021.113315_bib45","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1101\/gr.155465.113","article-title":"Country-specific antibiotic use practices impact the human gut resistome","volume":"23","author":"Forslund","year":"2013","journal-title":"Genome Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib46","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1080\/10409230701648494","article-title":"Stress-induced mutagenesis in bacteria","volume":"42","author":"Foster","year":"2007","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1016\/j.jenvman.2021.113315_bib47","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1128\/AAC.01495-10","article-title":"Oxidative stress induction of the MexXY multidrug efflux genes and promotion of aminoglycoside resistance development in Pseudomonas aeruginosa","volume":"55","author":"Fraud","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib48","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1371\/journal.pbio.0030238","article-title":"Precise temporal modulation in the response of the SOS DNA repair network in individual bacteria","volume":"3","author":"Friedman","year":"2005","journal-title":"PLoS Biol."},{"key":"10.1016\/j.jenvman.2021.113315_bib49","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1006\/bbrc.2000.2727","article-title":"Characterization of large plasmids encoding resistance to toxic heavy metals in Salmonella abortus equi","volume":"272","author":"Ghosh","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jenvman.2021.113315_bib50","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1111\/j.1365-2958.2011.07544.x","article-title":"Chlorinated phenols control the expression of the multidrug resistance efflux pump MexAB-OprM in Pseudomonas aeruginosa by interacting with NalC","volume":"79","author":"Ghosh","year":"2011","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib51","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/ismej.2014.106","article-title":"Improved annotation of antibiotic resistance determinants reveals microbial resistomes cluster by ecology","volume":"9","author":"Gibson","year":"2015","journal-title":"ISME J."},{"key":"10.1016\/j.jenvman.2021.113315_bib52","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1128\/AEM.66.1.125-132.2000","article-title":"Impact of an urban effluent on antibiotic resistance of","volume":"66","author":"Go\u00f1i-Urriza","year":"2000","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib53","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1128\/MMBR.00007-08","article-title":"Convergence of molecular, modeling, and systems approaches for an understanding of the Escherichia coli heat shock response","volume":"72","author":"Guisbert","year":"2008","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.jenvman.2021.113315_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.ppat.1002158","article-title":"Selection of resistant bacteria at very low antibiotic concentrations","volume":"7","author":"Gullberg","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jenvman.2021.113315_bib55","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.watres.2017.07.002","article-title":"Metagenomic analysis reveals wastewater treatment plants as hotspots of antibiotic resistance genes and mobile genetic elements","volume":"123","author":"Guo","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib56","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1128\/AAC.46.5.1410-1416.2002","article-title":"tcrb, a gene conferring transferable copper resistance in Enterococcus faecium: occurrence, transferability, and linkage to macrolide and glycopeptide resistance","volume":"46","author":"Hasman","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0101033","article-title":"Impact of Acinetobacter baumannii superoxide dismutase on motility, virulence, oxidative stress resistance and susceptibility to antibiotics","volume":"9","author":"Heindorf","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.jenvman.2021.113315_bib58","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/jfd.12427","article-title":"Comprehensive antibiotic susceptibility profiling of Chilean Piscirickettsia salmonis field isolates","volume":"39","author":"Henr\u00edquez","year":"2016","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.jenvman.2021.113315_bib59","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3389\/fvets.2018.00176","article-title":"Illumina next generation sequencing for the analysis of eimeria populations in commercial broilers and indigenous chickens","volume":"5","author":"Hinsu","year":"2018","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.jenvman.2021.113315_bib60","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev.micro.57.030502.090938","article-title":"Pathways of oxidative damage","volume":"57","author":"Imlay","year":"2003","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib61","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.chemosphere.2018.10.114","article-title":"Co-selection of multi-antibiotic resistance in bacterial pathogens in metal and microplastic contaminated environments: an emerging health threat","volume":"215","author":"Imran","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.jenvman.2021.113315_bib62","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.tig.2010.10.001","article-title":"Bacterial pathogen evolution: breaking news","volume":"27","author":"Jackson","year":"2011","journal-title":"Trends Genet."},{"key":"10.1016\/j.jenvman.2021.113315_bib63","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.1038\/s41598-020-60035-0","article-title":"Antibiotic resistance in bacterial isolates from freshwater samples in fildes peninsula, king George Island, Antarctica","volume":"10","author":"Jara","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jenvman.2021.113315_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2019.126309","article-title":"Regulatory rewiring through global gene regulations by PhoB and alarmone (p)ppGpp under various stress conditions","author":"Jha","year":"2019","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib65","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jhazmat.2012.07.040","article-title":"Antibiotic resistance gene abundances associated with antibiotics and heavy metals in animal manures and agricultural soils adjacent to feedlots in Shanghai; China","volume":"235\u2013236","author":"Ji","year":"2012","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.jenvman.2021.113315_bib66","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1038\/s41396-020-0656-9","article-title":"Chlorine disinfection promotes the exchange of antibiotic resistance genes across bacterial genera by natural transformation","volume":"14","author":"Jin","year":"2020","journal-title":"ISME J."},{"key":"10.1016\/j.jenvman.2021.113315_bib67","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep23012","article-title":"Metagenomic and functional analyses of the consequences of reduction of bacterial diversity on soil functions and bioremediation in diesel-contaminated microcosms","volume":"6","author":"Jung","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jenvman.2021.113315_bib68","doi-asserted-by":"crossref","first-page":"896","DOI":"10.2174\/1381612824666180219130659","article-title":"Antibacterial metal oxide nanoparticles: challenges in Interpreting the literature","volume":"24","author":"Kadiyala","year":"2018","journal-title":"Curr. Pharmaceut. Des."},{"key":"10.1016\/j.jenvman.2021.113315_bib69","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.tim.2017.09.005","article-title":"Antibiotic-resistance genes in waste water","volume":"26","author":"Karkman","year":"2018","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib70","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1093\/jac\/dkp347","article-title":"Decreased fluoroquinolone susceptibility in mutants of Salmonella serovars other than Typhimurium: detection of novel mutations involved in modulated expression of ramA and soxS","volume":"64","author":"Kehrenberg","year":"2009","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib71","doi-asserted-by":"crossref","first-page":"104996","DOI":"10.1371\/journal.pone.0104996","article-title":"Random whole metagenomic sequencing for forensic discrimination of soils","volume":"9","author":"Khodakova","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.jenvman.2021.113315_bib72","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1369-5274(03)00039-0","article-title":"The role of Fe-S proteins in sensing and regulation in bacteria","volume":"6","author":"Kiley","year":"2003","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib73","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.cell.2007.06.049","article-title":"A common mechanism of cellular death induced by bactericidal antibiotics","volume":"130","author":"Kohanski","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.jenvman.2021.113315_bib74","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.molcel.2010.01.003","article-title":"Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis","volume":"37","author":"Kohanski","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jenvman.2021.113315_bib75","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/nrmicro2333","article-title":"How antibiotics kill bacteria: from targets to networks","volume":"8","author":"Kohanski","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib76","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1128\/AAC.45.1.38-43.2001","article-title":"A soxRS-constitutive mutation contributing to antibiotic resistance in a clinical isolate of Salmonella enterica (Serovar typhimurium)","volume":"45","author":"Koutsolioutsou","year":"2001","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib77","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S1473-3099(10)70143-2","article-title":"Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study","volume":"10","author":"Kumarasamy","year":"2010","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jenvman.2021.113315_bib78","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1111\/j.1462-2920.2009.02125.x","article-title":"Coevolution of antibiotic production and counter-resistance in soil bacteria","volume":"12","author":"Laskaris","year":"2010","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib79","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2015.01025","article-title":"Exploring antibiotic resistance genes and metal resistance genes in plasmid metagenomes from wastewater treatment plants","volume":"6","author":"Li","year":"2015","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib80","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1038\/ismej.2015.59","article-title":"Metagenomic and network analysis reveal wide distribution and co-occurrence of environmental antibiotic resistance genes","volume":"9","author":"Li","year":"2015","journal-title":"ISME J."},{"key":"10.1016\/j.jenvman.2021.113315_bib81","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1111\/j.1365-2958.2008.06382.x","article-title":"Depletion of thiol-containing proteins in response to quinones in Bacillus subtilis","volume":"69","author":"Liebeke","year":"2008","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib82","first-page":"920","article-title":"Preliminary report of SCCmec-types and antimicrobial susceptibilities of methicillin-resistant Staphylococcus aureus isolates from a university hospital in Thailand","volume":"41","author":"Lulitanond","year":"2010","journal-title":"Southeast Asian J. Trop. Med. Publ. Health"},{"key":"10.1016\/j.jenvman.2021.113315_bib83","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.watres.2015.09.010","article-title":"Prevalence and proliferation of antibiotic resistance genes in two municipal wastewater treatment plants","volume":"85","author":"Mao","year":"2015","journal-title":"Water Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib84","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/978-3-319-06068-2_23","article-title":"Oxidative stress and antibiotic resistance in bacterial pathogens: state of the art, methodologies, and future trends","volume":"806","author":"Marrakchi","year":"2014","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jenvman.2021.113315_bib85","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.tim.2013.11.001","article-title":"The role of aquatic ecosystems as reservoirs of antibiotic resistance","volume":"22","author":"Marti","year":"2014","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib86","doi-asserted-by":"crossref","first-page":"5873","DOI":"10.1007\/s11356-014-2509-4","article-title":"Aquatic environments polluted with antibiotics and heavy metals: a human health hazard","volume":"21","author":"Martins","year":"2014","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib87","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1574-6968.2000.tb09158.x","article-title":"A multidrug efflux transporter in Listeria monocytogenes","volume":"187","author":"Mata","year":"2000","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.jenvman.2021.113315_bib88","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.mib.2020.02.002","article-title":"Horizontal transfer of antibiotic resistance genes in the human gut microbiome","volume":"53","author":"McInnes","year":"2020","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib89","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1093\/jac\/dkn123","article-title":"Transferable, multiple antibiotic and mercury resistance in Atlantic Canadian isolates of Aeromonas salmonicida subsp. salmonicida is associated with carriage of an IncA\/C plasmid similar to the Salmonella enterica plasmid pSN254","volume":"61","author":"McIntosh","year":"2008","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib90","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1128\/AEM.00578-06","article-title":"Environmental stress and antibiotic resistance in food-related pathogens","volume":"73","author":"McMahon","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib91","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1126\/science.1120096","article-title":"Microbiology: chitin induces natural competence in vibrio cholerae","volume":"310","author":"Meibom","year":"2005","journal-title":"Science (80-"},{"key":"10.1016\/j.jenvman.2021.113315_bib92","doi-asserted-by":"crossref","first-page":"W566","DOI":"10.1093\/nar\/gkv468","article-title":"ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap","volume":"43","author":"Metsalu","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib93","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1186\/1471-2105-9-386","article-title":"The metagenomics RAST server - a public resource for the automatic phylogenetic and functional analysis of metagenomes","volume":"9","author":"Meyer","year":"2008","journal-title":"BMC Bioinf."},{"key":"10.1016\/j.jenvman.2021.113315_bib94","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s40168-017-0337-8","article-title":"More than 2500 years of oil exposure shape sediment microbiomes with the potential for syntrophic degradation of hydrocarbons linked to methanogenesis","volume":"5","author":"Michas","year":"2017","journal-title":"Microbiome"},{"key":"10.1016\/j.jenvman.2021.113315_bib95","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.envint.2018.12.050","article-title":"Pollution from azithromycin-manufacturing promotes macrolide-resistance gene propagation and induces spatial and seasonal bacterial community shifts in receiving river sediments","volume":"123","author":"Milakovi\u0107","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.jenvman.2021.113315_bib96","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/j.resmic.2005.05.011","article-title":"Present-day mercury resistance transposons are common in bacteria preserved in permafrost grounds since the Upper Pleistocene","volume":"156","author":"Mindlin","year":"2005","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib97","doi-asserted-by":"crossref","DOI":"10.3390\/antiox9050361","article-title":"Oxidative stress-generating antimicrobials, a novel strategy to overcome antibacterial resistance","volume":"9","author":"Mourenza","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.jenvman.2021.113315_bib98","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.watres.2010.08.033","article-title":"Release of antibiotic resistant bacteria and genes in the effluent and biosolids of five wastewater utilities in Michigan","volume":"45","author":"Munir","year":"2011","journal-title":"Water Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib99","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1093\/jac\/dkw415","article-title":"A sampling and metagenomic sequencing-based methodology for monitoring antimicrobial resistance in swine herds","volume":"72","author":"Munk","year":"2017","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib100","first-page":"320","article-title":"All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis","volume":"14","author":"Napolitano","year":"2001","journal-title":"Chemtracts"},{"key":"10.1016\/j.jenvman.2021.113315_bib101","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1577\/H07-043.1","article-title":"Oxytetracycline treatment reduces bacterial diversity of intestinal microbiota of Atlantic salmon","volume":"20","author":"Navarrete","year":"2008","journal-title":"J. Aquat. Anim. Health"},{"key":"10.1016\/j.jenvman.2021.113315_bib102","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.cub.2014.03.036","article-title":"Large-scale metagenomic-based study of antibiotic resistance in the environment","volume":"24","author":"Nesme","year":"2014","journal-title":"Curr. Biol."},{"key":"10.1016\/j.jenvman.2021.113315_bib103","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/s11157-017-9438-x","article-title":"Status of pathogens, antibiotic resistance genes and antibiotic residues in wastewater treatment systems","volume":"16","author":"Nnadozie","year":"2017","journal-title":"Rev. Environ. Sci. Biotechnol."},{"key":"10.1016\/j.jenvman.2021.113315_bib104","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/lam.12414","article-title":"Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site","volume":"61","author":"Nonaka","year":"2015","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib105","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1111\/j.1365-2672.2009.04574.x","article-title":"Copper-resistant halophilic bacterium isolated from the polluted Maruit Lake, Egypt","volume":"108","author":"Osman","year":"2010","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib106","doi-asserted-by":"crossref","DOI":"10.1016\/S1473-3099(10)70053-0","article-title":"Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Europe","author":"Otter","year":"2010","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jenvman.2021.113315_bib107","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1128\/AAC.01005-08","article-title":"Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar eNteritidis: Involvement of ramA and other global regulators","volume":"53","author":"O'Regan","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib108","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkt1252","article-title":"BacMet: antibacterial biocide and metal resistance genes database","author":"Pal","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib109","doi-asserted-by":"crossref","DOI":"10.1186\/s12864-015-2153-5","article-title":"Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential","volume":"16","author":"Pal","year":"2015","journal-title":"BMC Genom."},{"key":"10.1016\/j.jenvman.2021.113315_bib110","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1186\/1471-2164-10-481","article-title":"Characterization of the oxidative stress stimulon and PerR regulon of Campylobacter jejuni","volume":"10","author":"Palyada","year":"2009","journal-title":"BMC Genom."},{"key":"10.1016\/j.jenvman.2021.113315_bib111","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1038\/35101607","article-title":"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18","volume":"413","author":"Parkhill","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.jenvman.2021.113315_bib112","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s00284-017-1357-0","article-title":"An Insight into phage diversity at environmental habitats using comparative metagenomics approach","volume":"75","author":"Parmar","year":"2018","journal-title":"Curr. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib113","article-title":"Heavy metal resistance determinants of the foodborne pathogen listeria monocytogenes","volume":"10","author":"Parsons","year":"2019","journal-title":"Genes"},{"key":"10.1016\/j.jenvman.2021.113315_bib114","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2012.00024","article-title":"Plasmid-mediated quinolone resistance; interactions between human, animal, and environmental ecologies","volume":"3","author":"Poirel","year":"2012","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib115","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0167-7799(00)01542-0","article-title":"Redox-operated genetic switches: the SoxR and OxyR transcription factors","volume":"19","author":"Pomposiello","year":"2001","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.jenvman.2021.113315_bib116","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1093\/jac\/dks196","article-title":"Bacterial stress responses as determinants of antimicrobial resistance","volume":"67","author":"Poole","year":"2012","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib117","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12864-018-5137-4","article-title":"Whole genome sequencing analysis of multiple Salmonella serovars provides insights into phylogenetic relatedness, antimicrobial resistance, and virulence markers across humans, food animals and agriculture environmental sources","volume":"19","author":"Pornsukarom","year":"2018","journal-title":"BMC Genom."},{"key":"10.1016\/j.jenvman.2021.113315_bib118","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/nar\/gki192","article-title":"Preferential binding and structural distortion by Fe2+ at RGGG-containing DNA sequences correlates with enhanced oxidative cleavage at such sequences","volume":"33","author":"Rai","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib119","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pbio.1002198","article-title":"Imperfect vaccination can enhance the transmission of highly virulent pathogens","volume":"13","author":"Read","year":"2015","journal-title":"PLoS Biol."},{"key":"10.1016\/j.jenvman.2021.113315_bib120","series-title":"The Evolution of Antibiotic- and Host Ecosystems","first-page":"213","author":"Roberts","year":"2009"},{"key":"10.1016\/j.jenvman.2021.113315_bib121","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/j.1365-2443.2006.00982.x","article-title":"Impact of reactive oxygen species on spontaneous mutagenesis in Escherichia coli","volume":"11","author":"Sakai","year":"2006","journal-title":"Gene Cell."},{"key":"10.1016\/j.jenvman.2021.113315_bib122","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1093\/jac\/dkr405","article-title":"Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak","volume":"67","author":"Sandegren","year":"2012","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib123","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.scitotenv.2019.03.162","article-title":"Antibiotic resistance in drinking water systems: occurrence, removal, and human health risks","volume":"669","author":"Sanganyado","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jenvman.2021.113315_bib124","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1574-6941.2003.tb01073.x","article-title":"Detection of antibiotic-resistant bacteria and their resistance genes in wastewater, surface water, and drinking water biofilms","volume":"43","author":"Schwartz","year":"2003","journal-title":"FEMS Microbiol. Ecol."},{"key":"10.1016\/j.jenvman.2021.113315_bib125","doi-asserted-by":"crossref","first-page":"48742","DOI":"10.1074\/jbc.M408754200","article-title":"Are respiratory enzymes the primary sources of intracellular hydrogen peroxide?","volume":"279","author":"Seaver","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jenvman.2021.113315_bib126","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/1758-2229.12011","article-title":"Distribution of antibiotic resistance genes in glacier environments","volume":"5","author":"Segawa","year":"2013","journal-title":"Environ. Microbiol. Rep."},{"key":"10.1016\/j.jenvman.2021.113315_bib127","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2012.00399","article-title":"Heavy metal driven co-selection of antibiotic resistance in soil and water bodies impacted by agriculture and aquaculture","author":"Seiler","year":"2012","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jenvman.2021.113315_bib128","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1093\/jac\/dkt479","article-title":"Co-transfer of resistance to high concentrations of copper and first-line antibiotics among Enterococcus from different origins (humans, animals, the environment and foods) and clonal lineages","volume":"69","author":"Silveira","year":"2014","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib129","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0168-9525(90)90278-E","article-title":"Bacterial defenses against oxidative stress","volume":"6","author":"Storz","year":"1990","journal-title":"Trends Genet."},{"key":"10.1016\/j.jenvman.2021.113315_bib130","first-page":"1","article-title":"Genetic characterization of two fully sequenced multi-drug resistant plasmids pP10164-2 and pP10164-3 from Leclercia adecarboxylata","volume":"6","author":"Sun","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jenvman.2021.113315_bib131","series-title":"Global Priority List of Antibiotic-Resistant Bacteria to Guide Research, Discovery, and Development of New Antibiotics","author":"Tacconelli","year":"2017"},{"key":"10.1016\/j.jenvman.2021.113315_bib132","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12917-020-02688-7","article-title":"Transition of microbiota in chicken cecal droppings from commercial broiler farms","volume":"17","author":"Takeshita","year":"2021","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.jenvman.2021.113315_bib133","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0133877","article-title":"Repurposing clinical molecule ebselen to combat drug resistant pathogens","volume":"10","author":"Thangamani","year":"2015","journal-title":"PloS One"},{"key":"10.1016\/j.jenvman.2021.113315_bib134","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1111\/1758-2229.12327","article-title":"Antimicrobial resistance genes in marine bacteria and human uropathogenic Escherichia coli from a region of intensive aquaculture","volume":"7","author":"Tomova","year":"2015","journal-title":"Environ. Microbiol. Rep."},{"key":"10.1016\/j.jenvman.2021.113315_bib135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40168-018-0424-5","article-title":"A reservoir of \u201chistorical\u201d antibiotic resistance genes in remote pristine Antarctic soils","volume":"6","author":"Van Goethem","year":"2018","journal-title":"Microbiome"},{"key":"10.1016\/j.jenvman.2021.113315_bib136","doi-asserted-by":"crossref","first-page":"5143","DOI":"10.1128\/AAC.05045-11","article-title":"SMB-1, a novel subclass B3 metallo-\u03b2-lactamase, associated with ISCR1 and a class 1 integron, from a carbapenem-resistant Serratia marcescens clinical isolate","volume":"55","author":"Wachino","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib137","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0065567","article-title":"The culturable soil antibiotic resistome: a community of multi-drug resistant bacteria","volume":"8","author":"Walsh","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.jenvman.2021.113315_bib138","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S1473-3099(11)70059-7","article-title":"Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study","volume":"11","author":"Walsh","year":"2011","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jenvman.2021.113315_bib139","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1128\/AAC.01087-08","article-title":"Contribution of oxidative damage to antimicrobial lethality","volume":"53","author":"Wang","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib140","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1038\/s41396-020-0679-2","article-title":"Non-antibiotic pharmaceuticals enhance the transmission of exogenous antibiotic resistance genes through bacterial transformation","volume":"14","author":"Wang","year":"2020","journal-title":"ISME J."},{"key":"10.1016\/j.jenvman.2021.113315_bib141","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/ismej.2008.8","article-title":"Influence of industrial contamination on mobile genetic elements: class 1 integron abundance and gene cassette structure in aquatic bacterial communities","volume":"2","author":"Wright","year":"2008","journal-title":"ISME J."},{"key":"10.1016\/j.jenvman.2021.113315_bib142","doi-asserted-by":"crossref","first-page":"4922","DOI":"10.1128\/AAC.00921-12","article-title":"Role of oxidative stress in persister tolerance","volume":"56","author":"Wu","year":"2012","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib143","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.chemosphere.2016.12.027","article-title":"Distribution of tetracycline resistance genes and AmpC \u03b2-lactamase genes in representative non-urban sewage plants and correlations with treatment processes and heavy metals","volume":"170","author":"Xu","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.jenvman.2021.113315_bib144","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.scitotenv.2019.07.267","article-title":"Science of the Total Environment Exploration of activated sludge resistome using metagenomics","volume":"692","author":"Yadav","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jenvman.2021.113315_bib145","doi-asserted-by":"crossref","first-page":"15591","DOI":"10.1073\/pnas.0704219104","article-title":"What a difference a decade makes: insights into translesion DNA synthesis","volume":"104","author":"Yang","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jenvman.2021.113315_bib146","series-title":"Exploring Variation of Antibiotic Resistance Genes in Activated Sludge over a Four-Year Period through a Metagenomic Approach","author":"Yang","year":"2013"},{"key":"10.1016\/j.jenvman.2021.113315_bib147","doi-asserted-by":"crossref","first-page":"7173","DOI":"10.1021\/es201045e","article-title":"Pathogenic bacteria in sewage treatment plants as revealed by 454 pyrosequencing","volume":"45","author":"Ye","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jenvman.2021.113315_bib148","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.ecoenv.2019.03.099","article-title":"Metagenomic characterization of antibiotic resistance genes in Antarctic soils","volume":"176","author":"Yuan","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jenvman.2021.113315_bib149","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1093\/jac\/dks496","article-title":"Genotyping using whole-genome sequencing is a realistic alternative to surveillance based on phenotypic antimicrobial susceptibility testing","volume":"68","author":"Zankari","year":"2013","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jenvman.2021.113315_bib150","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.envint.2019.02.052","article-title":"Metagenomic insights into the distribution of antibiotic resistome between the gut-associated environments and the pristine environments","volume":"126","author":"Zeng","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.jenvman.2021.113315_bib151","doi-asserted-by":"crossref","first-page":"3702","DOI":"10.1016\/j.scitotenv.2009.02.013","article-title":"Wastewater treatment contributes to selective increase of antibiotic resistance among Acinetobacter spp","volume":"407","author":"Zhang","year":"2009","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jenvman.2021.113315_bib152","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.chemosphere.2015.04.001","article-title":"Fate of antibiotic resistant cultivable heterotrophic bacteria and antibiotic resistance genes in wastewater treatment processes","volume":"135","author":"Zhang","year":"2015","journal-title":"Chemosphere"}],"container-title":["Journal of Environmental Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301479721013773?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301479721013773?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T09:51:28Z","timestamp":1759571488000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301479721013773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":152,"alternative-id":["S0301479721013773"],"URL":"https:\/\/doi.org\/10.1016\/j.jenvman.2021.113315","relation":{},"ISSN":["0301-4797"],"issn-type":[{"value":"0301-4797","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mobility of antibiotic resistance and its co-occurrence with metal resistance in pathogens under oxidative stress","name":"articletitle","label":"Article Title"},{"value":"Journal of Environmental Management","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jenvman.2021.113315","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113315"}}