{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T10:57:23Z","timestamp":1782730643134,"version":"3.54.5"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T00:00:00Z","timestamp":1694649600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Environmental Management"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.jenvman.2023.119001","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T08:55:39Z","timestamp":1696841739000},"page":"119001","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Application of biological early warning systems in wastewater treatment plants: Introducing a promising approach to monitor changing wastewater composition"],"prefix":"10.1016","volume":"347","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9432-7562","authenticated-orcid":false,"given":"Ali","family":"Kizgin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4852-9900","authenticated-orcid":false,"given":"Danina","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano","family":"Joss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliane","family":"Hollender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eberhard","family":"Morgenroth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7695-6549","authenticated-orcid":false,"given":"Cornelia","family":"Kienle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8751-974X","authenticated-orcid":false,"given":"Miriam","family":"Langer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jenvman.2023.119001_bib1","volume":"33","year":"2020","journal-title":"XP T 90-722-3 physiologiques et comportementales chez le gammare (crustac\u00e9 amphipode) \u2014 Partie 3 : Mesure du taux d \u2019 alimentation"},{"issue":"7","key":"10.1016\/j.jenvman.2023.119001_bib2","doi-asserted-by":"crossref","first-page":"4110","DOI":"10.1021\/acs.est.9b07085","article-title":"Assessing emissions from pharmaceutical manufacturing based on temporal high-resolution Mass spectrometry data","volume":"54","author":"Anliker","year":"2020","journal-title":"Environ. Sci. Technol."},{"issue":"23","key":"10.1016\/j.jenvman.2023.119001_bib3","doi-asserted-by":"crossref","first-page":"15046","DOI":"10.1021\/acs.est.0c05178","article-title":"Quantification of active ingredient losses from formulating pharmaceutical industries and contribution to wastewater treatment plant emissions","volume":"54","author":"Anliker","year":"2020","journal-title":"Environ. Sci. Technol."},{"issue":"18","key":"10.1016\/j.jenvman.2023.119001_bib4","doi-asserted-by":"crossref","first-page":"10652","DOI":"10.1021\/acs.est.7b02912","article-title":"Selective uptake and bioaccumulation of antidepressants in fish from effluent-impacted Niagara River","volume":"51","author":"Arnnok","year":"2017","journal-title":"Environ. Sci. Technol."},{"issue":"5","key":"10.1016\/j.jenvman.2023.119001_bib5","doi-asserted-by":"crossref","first-page":"3084","DOI":"10.1021\/acs.est.6b06163","article-title":"Toxic mixtures in time - the sequence makes the poison","volume":"51","author":"Ashauer","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jenvman.2023.119001_bib6","series-title":"Static, Acute 48-hour EC50 of DPX-14740-165 (Karmex DF) to Daphnia Magna","author":"Baer","year":"1991"},{"issue":"7","key":"10.1016\/j.jenvman.2023.119001_bib7","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1002\/jat.3212","article-title":"Automated swimming activity monitor for examining temporal patterns of toxicant effects on individual Daphnia magna","volume":"36","author":"Bahrndorff","year":"2016","journal-title":"J. Appl. Toxicol."},{"issue":"1","key":"10.1016\/j.jenvman.2023.119001_bib8","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1017\/S0952836905007223","article-title":"The acanthocephalan parasite Polymorphus minutus alters the geotactic and clinging behaviors of two sympatric amphipod hosts: the native Gammarus pulex and the invasive Gammarus roeseli","volume":"267","author":"Bauer","year":"2005","journal-title":"J. Zool."},{"issue":"5","key":"10.1016\/j.jenvman.2023.119001_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2166\/wst.2007.550","article-title":"Evaluation of advanced treatment technologies for the elimination of pharmaceutical compounds","volume":"56","author":"Baumgarten","year":"2007","journal-title":"Water Sci. Technol."},{"issue":"7","key":"10.1016\/j.jenvman.2023.119001_bib10","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/j.bios.2004.09.019","article-title":"The combined SPE:ToxY-PAM phytotoxicity assay; application and appraisal of a novel biomonitoring tool for the aquatic environment","volume":"20","author":"Bengtson Nash","year":"2005","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.jenvman.2023.119001_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.147796","article-title":"Advances in real-time monitoring of water quality using automated analysis of animal behavior","volume":"789","author":"Bownik","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jenvman.2023.119001_bib12","series-title":"Multiple Comparisons Using R","author":"Bretz","year":"2016"},{"issue":"8","key":"10.1016\/j.jenvman.2023.119001_bib13","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1002\/etc.2979","article-title":"Exploration of Daphnia behavioral effect profiles induced by a broad range of toxicants with different modes of action","volume":"34","author":"Chevalier","year":"2015","journal-title":"Environ. Toxicol. Chem."},{"issue":"Issue 1","key":"10.1016\/j.jenvman.2023.119001_bib14","article-title":"Ecology, epidemiology and evolution of parasitism in","volume":"3","author":"Ebert","year":"2005","journal-title":"Evolution"},{"key":"10.1016\/j.jenvman.2023.119001_bib15","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.scitotenv.2013.03.025","article-title":"Effects of municipal wastewater on aquatic ecosystem structure and function in the receiving stream","volume":"454\u2013455","author":"Englert","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jenvman.2023.119001_bib16","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.scitotenv.2018.12.035","article-title":"Wastewater alters feeding rate but not vitellogenin level of Gammarus fossarum (Amphipoda)","volume":"657","author":"Ganser","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jenvman.2023.119001_bib17","series-title":"Online Biomonitoring zur Qualit\u00e4tskontrolle in Kl\u00e4ranlagen: Erfahrungsbericht. Gwf Wasser Abwasser \u2013 Das Portal Zum Wasserfach, 63\u201372","author":"Gerhardt","year":"2019"},{"key":"10.1016\/j.jenvman.2023.119001_bib18","first-page":"20","article-title":"Online Biomonitoring for integrated smart real-time water management","volume":"3","author":"Gerhardt","year":"2020","journal-title":"Water Solut"},{"issue":"9","key":"10.1016\/j.jenvman.2023.119001_bib19","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1039\/b706619h","article-title":"Biomonitoring with Gammarus pulex at the meuse (NL), aller (GER) and rhine (F) rivers with the online multispecies freshwater biomonitor","volume":"9","author":"Gerhardt","year":"2007","journal-title":"J. Environ. Monit."},{"key":"10.1016\/j.jenvman.2023.119001_bib20","series-title":"Algae: an Introduction to Phycology","author":"Hoek","year":"1995"},{"key":"10.1016\/j.jenvman.2023.119001_bib21","series-title":"Integrated and Hybrid Process Technology for Water and Wastewater Treatment","first-page":"487","article-title":"Emerging micropollutants in municipal wastewater: occurrence and treatment options","author":"Hofman","year":"2021"},{"issue":"June","key":"10.1016\/j.jenvman.2023.119001_bib22","article-title":"Environmentally relevant concentrations of methamphetamine and sertraline modify the behavior and life history traits of an aquatic invertebrate","volume":"213","author":"Hossain","year":"2019","journal-title":"Aquat. Toxicol."},{"issue":"2","key":"10.1016\/j.jenvman.2023.119001_bib23","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s10646-005-0052-2","article-title":"Behavioral changes and acute toxicity to the freshwater shrimp Atyaephyra desmaresti Millet (Decapoda: natantia) from exposure to acid mine drainage","volume":"15","author":"Janssens de Bisthoven","year":"2006","journal-title":"Ecotoxicology"},{"issue":"1","key":"10.1016\/j.jenvman.2023.119001_bib24","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.ecoenv.2006.03.016","article-title":"Toxicity and hazard of selective serotonin reuptake inhibitor antidepressants fluoxetine, fluvoxamine, and sertraline to algae","volume":"67","author":"Johnson","year":"2007","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"12","key":"10.1016\/j.jenvman.2023.119001_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0226278","article-title":"Effects of treated wastewater on the ecotoxicity of small streams - unravelling the contribution of chemicals causing effects","volume":"14","author":"Kienle","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jenvman.2023.119001_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.118084","article-title":"Evaluation of a full-scale wastewater treatment plant with ozonation and different post-treatments using a broad range of in vitro and in vivo bioassays","volume":"212","author":"Kienle","year":"2022","journal-title":"Water Research"},{"key":"10.1016\/j.jenvman.2023.119001_bib27","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.scitotenv.2013.04.010","article-title":"Occurrence and behavior of pesticides in wastewater treatment plants and their environmental impact","volume":"458\u2013460","author":"K\u00f6ck-Schulmeyer","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jenvman.2023.119001_bib28","first-page":"95","article-title":"Aquatic biological early warning systems: an overview","author":"Kramer","year":"1991","journal-title":"Bioindicators and environmental management"},{"issue":"5","key":"10.1016\/j.jenvman.2023.119001_bib30","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1002\/1522-7278(2000)15:5<390::AID-TOX6>3.0.CO;2-H","article-title":"Monitoring of surface water by ultrasensitive Daphnia toximeter","volume":"15","author":"Lechelt","year":"2000","journal-title":"Environ. Toxicol.: Int. J."},{"issue":"2","key":"10.1016\/j.jenvman.2023.119001_bib31","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.envpol.2008.09.020","article-title":"EU-wide survey of polar organic persistent pollutants in European river waters","volume":"157","author":"Loos","year":"2009","journal-title":"Environ. Pollut."},{"issue":"7","key":"10.1016\/j.jenvman.2023.119001_bib32","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1897\/03-231","article-title":"Avoidance of copper contamination by field populations of Daphnia longispina","volume":"23","author":"Lopes","year":"2004","journal-title":"Environ. Toxicol. Chem.: Int. J."},{"key":"10.1016\/j.jenvman.2023.119001_bib71","series-title":"Simultaneous online chemical and behaviour measurements in the field indicate that pesticide peaks alter gammarid behavior patterns","author":"Lopez-Mangas","year":"2023"},{"key":"10.1016\/j.jenvman.2023.119001_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.115386","article-title":"The effects of wastewater effluent on multiple behaviors in the amphipod, Gammarus pulex","volume":"267","author":"Love","year":"2020","journal-title":"Environ. Pollut."},{"issue":"2","key":"10.1016\/j.jenvman.2023.119001_bib34","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1006\/eesa.2001.2113","article-title":"Toxicity of 40 herbicides to the green alga Chlorella vulgaris","volume":"51","author":"Ma","year":"2002","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"9","key":"10.1016\/j.jenvman.2023.119001_bib35","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/j.marpolbul.2008.05.023","article-title":"Comparative effects of herbicides on photosynthesis and growth of tropical estuarine microalgae","volume":"56","author":"Magnusson","year":"2008","journal-title":"Mar. Pollut. Bull."},{"issue":"2","key":"10.1016\/j.jenvman.2023.119001_bib36","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/etc.5620210219","article-title":"Evaluation of the Gammarus pulex in-situ feeding assay as a biomonitor of water quality: robustness, responsiveness, and relevance","volume":"21","author":"Maltby","year":"2002","journal-title":"Environ. Toxicol. Chem.: Int. J."},{"issue":"10","key":"10.1016\/j.jenvman.2023.119001_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11270-021-05369-9","article-title":"Ecotoxicological assessment and environmental risk of the insecticide chlorpyrifos for aquatic neotropical indicators","volume":"232","author":"Marques","year":"2021","journal-title":"Water, Air, Soil Pollut."},{"issue":"3","key":"10.1016\/j.jenvman.2023.119001_bib38","first-page":"43","article-title":"Determination of chlorpyrifos in surface water using SPE-DI-SPME\/GC-ECD. Studia Universitatis Babes-Bolyai","volume":"59","author":"Miclean","year":"2014","journal-title":"Chem"},{"issue":"2","key":"10.1016\/j.jenvman.2023.119001_bib39","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/j.1551-8833.2007.tb07873.x","article-title":"An Online real-time biomonitor for contaminant surveillance in water supplies","volume":"99","author":"Mikol","year":"2007","journal-title":"J. Am. Water Works Assoc."},{"issue":"2","key":"10.1016\/j.jenvman.2023.119001_bib40","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.ecoenv.2008.05.002","article-title":"Aquatic ecotoxicity of the selective serotonin reuptake inhibitor sertraline hydrochloride in a battery of freshwater test species","volume":"72","author":"Minagh","year":"2009","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"2","key":"10.1016\/j.jenvman.2023.119001_bib41","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1021\/es504808g","article-title":"Transgenerational effects of two antidepressants (sertraline and venlafaxine) on Daphnia magna life history traits","volume":"49","author":"Minguez","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jenvman.2023.119001_bib42","first-page":"2","article-title":"Report of the project Weiterentwicklung eines mathematischen Modells zur on-line-Erkennung von signifikanten Messwert aenderungen in dynamischen Biotestrerfahren","volume":"1","author":"Moldaenke","year":"1998","journal-title":"DCWK"},{"key":"10.1016\/j.jenvman.2023.119001_bib43","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.envpol.2019.04.118","article-title":"Global scanning of selective serotonin reuptake inhibitors: occurrence, wastewater treatment and hazards in aquatic systems","volume":"250","author":"Mole","year":"2019","journal-title":"Environ. Pollut."},{"issue":"2","key":"10.1016\/j.jenvman.2023.119001_bib44","first-page":"1","article-title":"Toxicity evaluation of wastewater treatment plant effluents using Daphnia magna","volume":"2","author":"Movahedian","year":"2005","journal-title":"Journal of Environmental Health Science & Engineering"},{"issue":"March","key":"10.1016\/j.jenvman.2023.119001_bib45","article-title":"Does the antidepressant sertraline show chronic effects on aquatic invertebrates at environmentally relevant concentrations? A case study with the keystone amphipod, Gammarus locusta","volume":"183","author":"Neuparth","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jenvman.2023.119001_bib46","first-page":"305","article-title":"The algae toximeter for continuous water monitoring","volume":"89","author":"Noack","year":"1992","journal-title":"Schriftenreihe des Vereins fur Wasser-, Boden-und Lufthygiene"},{"key":"10.1016\/j.jenvman.2023.119001_bib47","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ecoenv.2007.08.022","article-title":"Comparison of the fate and toxicity of chlorpyrifos-laboratory versus a coastal mesocosm system","volume":"71","author":"Pablo","year":"2008","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jenvman.2023.119001_bib48","series-title":"Changepoint Detection for Acoustic Sensing Signals. December, 1\u2013181","author":"Pickering","year":"2015"},{"key":"10.1016\/j.jenvman.2023.119001_bib49","series-title":"Smop: Subset Multivariate Optimal Partitioning. R Package Version 0.1.1","author":"Pickering","year":"2019"},{"key":"10.1016\/j.jenvman.2023.119001_bib50","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s10811-005-4945-5","article-title":"Selective real-time herbicide monitoring by an array chip biosensor employing diverse microalgae","volume":"17","author":"Podola","year":"2005","journal-title":"J. Appl. Phycol."},{"key":"10.1016\/j.jenvman.2023.119001_bib72","series-title":"R: A language and environment for statistical computing","year":"2022"},{"issue":"10","key":"10.1016\/j.jenvman.2023.119001_bib51","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1002\/etc.273","article-title":"Toxicokinetic variation in 15 freshwater arthropod species exposed to the insecticide chlorpyrifos","volume":"29","author":"Rubach","year":"2010","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.jenvman.2023.119001_bib52","series-title":"Bureau of Sport Fisheries and Wildlife Technical Paper 25","article-title":"Toxicity of pesticides to the Crustacean, Gammarus lacustris","author":"Sanders","year":"1969"},{"key":"10.1016\/j.jenvman.2023.119001_bib53","first-page":"1544","article-title":"Toxicities of some herbicides to 6 species of freshwater crustaceans","volume":"42","author":"Sanders","year":"1970","journal-title":"J. Water Pollut. Control Fed."},{"issue":"14","key":"10.1016\/j.jenvman.2023.119001_bib54","doi-asserted-by":"crossref","first-page":"6167","DOI":"10.1021\/es2013006","article-title":"Occurrence and toxicity of 331 organic pollutants in large rivers of north Germany over a decade (1994 to 2004)","volume":"45","author":"Sch\u00e4fer","year":"2011","journal-title":"Environ. Sci. Technol."},{"issue":"11","key":"10.1016\/j.jenvman.2023.119001_bib55","doi-asserted-by":"crossref","first-page":"2554","DOI":"10.1016\/j.bios.2006.10.018","article-title":"Methodology and evaluation of a highly sensitive algae toxicity test based on multiwell chlorophyll fluorescence imaging","volume":"22","author":"Schreiber","year":"2007","journal-title":"Biosens. Bioelectron."},{"issue":"5790","key":"10.1016\/j.jenvman.2023.119001_bib56","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1126\/science.1127291","article-title":"The challenge of micropollutants in aquatic systems","volume":"313","author":"Schwarzenbach","year":"2006","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.jenvman.2023.119001_bib57","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1080\/00031305.1980.10483031","article-title":"Population marginal means in the linear model: an alternative to least squares means","volume":"34","author":"Searle","year":"1980","journal-title":"Am. Statistician"},{"issue":"1","key":"10.1016\/j.jenvman.2023.119001_bib58","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1046\/j.1365-2427.1998.00348.x","article-title":"Odour-induced antipredator behavior of the water flea, Ceriodaphnia reticulata, in varying predator and prey densities","volume":"40","author":"Seely","year":"1998","journal-title":"Freshw. Biol."},{"key":"10.1016\/j.jenvman.2023.119001_bib59","author":"Ternes"},{"issue":"1","key":"10.1016\/j.jenvman.2023.119001_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-020-64116-y","article-title":"Toxicity of ten herbicides to the tropical marine microalgae Rhodomonas salina","volume":"10","author":"Thomas","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jenvman.2023.119001_bib61","series-title":"The Pesticide Manual: a World Compendium","author":"Tomlin","year":"2009"},{"key":"10.1016\/j.jenvman.2023.119001_bib62","first-page":"309","article-title":"From small to large scale: a review of the swimming behavior of Daphnia","author":"Uttieri","year":"2014","journal-title":"Daphnia: Biology and Mathematics Perspectives"},{"key":"10.1016\/j.jenvman.2023.119001_bib63","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1007\/BF00201650","article-title":"Acute toxicity of chlorpyrifos to fish, a newt, and aquatic invertebrates","volume":"51","author":"van Wijngaarden","year":"1993","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.jenvman.2023.119001_bib64","series-title":"Ecological Characterization of Surface Waters in the Province of Overijssel, The Netherlands. Thesis, January 1990","first-page":"255","author":"Verdonschot","year":"1990"},{"issue":"Special Issue 1","key":"10.1016\/j.jenvman.2023.119001_bib65","first-page":"121","article-title":"Effects of a treated sewage effluent on behavioral traits in diamesa cinerella and daphnia magna","volume":"77","author":"Villa","year":"2018","journal-title":"J. Limnol."},{"key":"10.1016\/j.jenvman.2023.119001_bib66","first-page":"8","article-title":"Application of an online toxicity early warning system upstream of the influent of the activated sludge stage of the Hamburg sewage treatment plant network","author":"Voetz","year":"2015"},{"key":"10.1016\/j.jenvman.2023.119001_bib67","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.chemosphere.2018.07.018","article-title":"Behavior responses of zebrafish (Danio rerio) to aquatic environmental stresses in the characteristic of circadian rhythms","volume":"210","author":"Yang","year":"2018","journal-title":"Chemosphere"},{"issue":"1","key":"10.1016\/j.jenvman.2023.119001_bib68","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/etc.2404","article-title":"Optical bioassay for measuring sublethal toxicity of insecticides in Daphnia pulex","volume":"33","author":"Zein","year":"2014","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.jenvman.2023.119001_bib69","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.124752","article-title":"Potential effects of internal physio-ecological changes on the online biomonitoring of water quality: the behavior responses with circadian rhythms of zebrafish (Danio rerio) to different chemicals","volume":"239","author":"Zhao","year":"2020","journal-title":"Chemosphere"}],"container-title":["Journal of Environmental Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301479723017899?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301479723017899?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T11:06:50Z","timestamp":1759576010000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301479723017899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":70,"alternative-id":["S0301479723017899"],"URL":"https:\/\/doi.org\/10.1016\/j.jenvman.2023.119001","relation":{"is-supplemented-by":[{"id-type":"uri","id":"https:\/\/data.mendeley.com\/datasets\/bxkm2chkxw\/draft?a=f2a62dee-d3c4-4d80-9f5f-1ca650423aed","asserted-by":"subject"}]},"ISSN":["0301-4797"],"issn-type":[{"value":"0301-4797","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Application of biological early warning systems in wastewater treatment plants: Introducing a promising approach to monitor changing wastewater composition","name":"articletitle","label":"Article Title"},{"value":"Journal of Environmental Management","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jenvman.2023.119001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"119001"}}