{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T23:36:49Z","timestamp":1788910609372,"version":"build-2803163510"},"reference-count":34,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2006,6,1]],"date-time":"2006-06-01T00:00:00Z","timestamp":1149120000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2006,6]]},"DOI":"10.1016\/j.jep.2006.01.002","type":"journal-article","created":{"date-parts":[[2006,2,22]],"date-time":"2006-02-22T12:28:35Z","timestamp":1140611315000},"page":"245-249","source":"Crossref","is-referenced-by-count":56,"title":["Hepatoprotective studies on Hedyotis corymbosa (L.) Lam."],"prefix":"10.1016","volume":"106","author":[{"given":"Sini","family":"Sadasivan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.G.","family":"Latha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Sasikumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Rajashekaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Shyamal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.J.","family":"Shine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2006.01.002_bib1","first-page":"981","article-title":"Protective effect of oleanolic acid and ursolic acid against lipid peroxidation","volume":"24","author":"Balanehru","year":"1991","journal-title":"Biochemistry International"},{"key":"10.1016\/j.jep.2006.01.002_bib2","first-page":"999","article-title":"Effects of rosemary extracts and major constituents on lipid oxidation and soyabean lipoxygenase activity","volume":"69","author":"Chang","year":"1994","journal-title":"Journal of American Oil Chemical Society"},{"key":"10.1016\/j.jep.2006.01.002_bib3","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1142\/S0192415X88000194","article-title":"The pharmacological and pathological studies on several hepatic protective crude drugs from Taiwan","volume":"16","author":"Chiu","year":"1988","journal-title":"American Journal of Chinese Medicine"},{"key":"10.1016\/j.jep.2006.01.002_bib4","first-page":"307","article-title":"Natural products and plants as liver protecting drugs","volume":"57","author":"Handa","year":"1986","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jep.2006.01.002_bib5","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1159\/000136547","article-title":"Acetaminophen-induced hepatic necrosis. IV. Metabolic disposition of toxic and non-toxic doses of acetaminophen","volume":"12","author":"Jollow","year":"1974","journal-title":"Pharmacology"},{"key":"10.1016\/j.jep.2006.01.002_bib6","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1002\/jps.3030490821","article-title":"Note on the constituents of the Indian medicinal plant Oldenlandia corymbosa Linn","volume":"49","author":"Khastgir","year":"1960","journal-title":"Journal of the American Pharmaceutical Association"},{"key":"10.1016\/j.jep.2006.01.002_bib7","first-page":"850","article-title":"Calcium, magnesium, phosphorous and phosphatase","volume":"vol. 1","author":"King","year":"1980"},{"key":"10.1016\/j.jep.2006.01.002_bib8","volume":"vol. 2","author":"Kirtikar","year":"1994"},{"key":"10.1016\/j.jep.2006.01.002_bib9","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/0014-4800(70)90075-4","article-title":"Liver restitution after acute galactosamine hepatitis: autoradiographic and biochemical studies in rats","volume":"12","author":"Lesch","year":"1970","journal-title":"Experimental Molecular Pathology"},{"key":"10.1016\/j.jep.2006.01.002_bib10","first-page":"180","article-title":"Development of crude drug resources from Taiwan: pharmacognostical studies on a Chinese crude drug","volume":"41","author":"Lin","year":"1987","journal-title":"Shoyakugaku Zasshi"},{"key":"10.1016\/j.jep.2006.01.002_bib11","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1142\/S0192415X02000405","article-title":"Anti-inflammatory and hepatoprotective activity of \u201cPeh-Hue-Juwa-Chi-Cao\u201d in male rats","volume":"30","author":"Lin","year":"2002","journal-title":"American Journal of Chinese Medicine"},{"key":"10.1016\/j.jep.2006.01.002_bib12","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1142\/S0192415X04001990","article-title":"Antioxidant activity of extracts of \u201cPeh-Hue-Juwa-Chi-Cao\u201d in a cell free system","volume":"32","author":"Lin","year":"2004","journal-title":"American Journal of Chinese Medicine"},{"key":"10.1016\/j.jep.2006.01.002_bib13","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0378-8741(95)90032-2","article-title":"Pharmacology of oleanolic acid and ursolic acid","volume":"49","author":"Liu","year":"1995","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2006.01.002_bib14","first-page":"400","article-title":"Protective effects of oleanolic acid on acetaminophen hepatotoxicity in mice","volume":"226","author":"Liu","year":"1993","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/j.jep.2006.01.002_bib15","first-page":"720","article-title":"The protection of oleanolic acid on d-galactosamine\/endotoxin-induced hepatotoxicity","volume":"13","author":"Liu","year":"1993","journal-title":"Toxicologist"},{"key":"10.1016\/j.jep.2006.01.002_bib16","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0021-9258(18)74392-5","article-title":"The determination of bilirubin with the photometric colorimeter","volume":"119","author":"Malloy","year":"1937","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.jep.2006.01.002_bib17","first-page":"95","article-title":"Inhibitory effects of monomeric and dimeric phenyl propanoids from mice on lipid peroxidation in vivo and in vitro","volume":"7","author":"Masao","year":"1993","journal-title":"Phytotherapy Research"},{"key":"10.1016\/j.jep.2006.01.002_bib18","first-page":"185","article-title":"Acetaminophen induced hepatic necrosis. I. Role of drug metabolism","volume":"187","author":"Mitchell","year":"1973","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/j.jep.2006.01.002_bib19","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0378-8741(98)00088-9","article-title":"Protective effect of HD-03, a herbal formulation against various hepatotoxic agents in rats","volume":"63","author":"Mitra","year":"1998","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2006.01.002_bib20","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1248\/cpb.39.2049","article-title":"Isolation of acyl iridoid glycosides from a Philippine medicinal plant Oldenlandia corymbosa","volume":"39","author":"Otsuka","year":"1991","journal-title":"Chemical and Pharmaceutical Bulletin"},{"key":"10.1016\/j.jep.2006.01.002_bib21","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0378-8741(89)90059-7","article-title":"The hepatoprotective principle of Hypoestes triflora leaves","volume":"26","author":"Puyvelde","year":"1989","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2006.01.002_bib22","first-page":"69","article-title":"Liver protection by Silymarin. In vitro effect on dissociated rat hepatocytes","volume":"26","author":"Ramellini","year":"1976","journal-title":"Arzneimittel Forschung (Drug Research)"},{"key":"10.1016\/j.jep.2006.01.002_bib23","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/ajcp\/28.1.56","article-title":"Determination of serum glutamate oxaloacetate and glutamic pyruvic acid transaminases","volume":"28","author":"Reitman","year":"1957","journal-title":"American Journal of Clinical Pathology"},{"key":"10.1016\/j.jep.2006.01.002_bib24","series-title":"Pathogenesis and Mechanism of Liver Cell Necrosis","article-title":"Liver morphology and enzyme release. Further studies in the isolated perfused rat liver","author":"Schmidt","year":"1975"},{"key":"10.1016\/j.jep.2006.01.002_bib25","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/ptr.2650060205","article-title":"Hepatoprotective activity in the rat of ursolic acid isolated from Eucalyptus hybrid","volume":"6","author":"Shukla","year":"1992","journal-title":"Phytotherapy Research"},{"key":"10.1016\/j.jep.2006.01.002_bib26","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1055\/s-2006-960010","article-title":"The hepatoprotective principle of Picrorrhiza kurroa","volume":"57","author":"Shukla","year":"1992","journal-title":"Planta Medica"},{"key":"10.1016\/j.jep.2006.01.002_bib27","first-page":"135","article-title":"Hepatoprotective activity of verbenalin on experimental liver damage in rodents","volume":"69","author":"Singh","year":"1998","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jep.2006.01.002_bib28","series-title":"Statistical Methods","author":"Snedecor","year":"1980"},{"key":"10.1016\/j.jep.2006.01.002_bib29","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1055\/s-2006-962691","article-title":"Comparative study of the efficacy of Pavetta indica and Osbeckia octandra in the treatment of liver function","volume":"53","author":"Thabrew","year":"1987","journal-title":"Planta Medica"},{"key":"10.1016\/j.jep.2006.01.002_bib30","series-title":"Biochemical Mechanisms of Liver Injury","first-page":"631","article-title":"Pathological aspects of liver injury produced by drugs","author":"Torrielli","year":"1978"},{"key":"10.1016\/j.jep.2006.01.002_bib31","volume":"vol. 3","author":"Warrier","year":"1995"},{"key":"10.1016\/j.jep.2006.01.002_bib32","first-page":"610","article-title":"Studies on Scutelariae radix. Effects on lipid peroxidation of rat liver","volume":"29","author":"Yoshiyuki","year":"1981","journal-title":"Chemical and Pharmaceutical Bulletin"},{"key":"10.1016\/j.jep.2006.01.002_bib33","first-page":"24","article-title":"Study on the mechanism of oleanolic acid against experimental liver injury in rats","volume":"8","author":"Zhang","year":"1992","journal-title":"Traditional Medicine and Clinical Pharmacology"},{"key":"10.1016\/j.jep.2006.01.002_bib34","series-title":"Diagnostic Enzymology","first-page":"1","article-title":"Enzymes in hepatic disease","author":"Zimmerman","year":"1970"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874106000031?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874106000031?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,24]],"date-time":"2021-07-24T06:28:32Z","timestamp":1627108112000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874106000031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["S0378874106000031"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2006.01.002","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2006,6]]}}}