{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T18:53:55Z","timestamp":1774551235832,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.jep.2006.09.041","type":"journal-article","created":{"date-parts":[[2006,10,18]],"date-time":"2006-10-18T05:56:53Z","timestamp":1161151013000},"page":"364-367","source":"Crossref","is-referenced-by-count":58,"title":["Analgesic activity of affinin, an alkamide from Heliopsis longipes (Compositae)"],"prefix":"10.1016","volume":"110","author":[{"given":"Mar\u00eda Yolanda","family":"Rios","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Berenice","family":"Aguilar-Guadarrama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda del Carmen","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2006.09.041_bib1","unstructured":"Aldrich library of 13C and 1H FT NMR spectra, vol. 3, 1992, p. 569A."},{"key":"10.1016\/j.jep.2006.09.041_bib2","unstructured":"Aldrich library of 13C and 1H FT NMR spectra, vol. 3, 1992, p. 569B."},{"key":"10.1016\/j.jep.2006.09.041_bib3","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1016\/0031-9422(88)80156-0","article-title":"Alkamides from the roots of Echinacea purpurea","volume":"27","author":"Bauer","year":"1988","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2006.09.041_bib4","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0031-9422(89)80042-1","article-title":"Alkamides from the roots of Echinacea angustifolia","volume":"28","author":"Bauer","year":"1989","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2006.09.041_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/mrc.1270030102","article-title":"Multiple NMR analysis of the affinin","volume":"3","author":"Correa","year":"1971","journal-title":"Organic Magnetic Resonance"},{"key":"10.1016\/j.jep.2006.09.041_bib6","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/BF00964852","article-title":"Influence of pipecolic acid on the release and uptake of [3H] GABA from brain slices of mouse cerebral cortex","volume":"14","author":"Guti\u00e9rrez","year":"1989","journal-title":"Neurochemical Research"},{"key":"10.1016\/j.jep.2006.09.041_bib7","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1021\/jo01169a007","article-title":"Correction of the source of affinin N-isobutyl-2,6,8-decatrienamide","volume":"12","author":"Jacobson","year":"1947","journal-title":"Journal of Organic Chemistry"},{"key":"10.1016\/j.jep.2006.09.041_bib8","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/nature01808","article-title":"Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex","volume":"424","author":"Jasmin","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.jep.2006.09.041_bib9","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/S0021-9673(00)80523-3","article-title":"Rapid high performance liquid chromatographic determination of aminoacids in synaptosomal extracts","volume":"198","author":"Karel","year":"1980","journal-title":"Journal of Chromatography"},{"key":"10.1016\/j.jep.2006.09.041_bib10","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement whit the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.jep.2006.09.041_bib11","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1021\/np50032a023","article-title":"Chemical constituents of Vernonia cin\u00e9rea, Part I. Isolation and spectral studies of triterpenes","volume":"47","author":"Misra","year":"1984","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2006.09.041_bib12","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1021\/np50124a018","article-title":"Presence of the bornyl ester of deca-2E,6Z,8E-trienoic acid in Heliopsis longipes roots","volume":"58","author":"Molina","year":"1995","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2006.09.041_bib13","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0305-1978(95)00099-2","article-title":"Purely olefinic alkamides in Heliopsis longipes and Acmella (Spilanthes) oppositifolia","volume":"24","author":"Molina","year":"1996","journal-title":"Biochemical Systematic and Ecology"},{"key":"10.1016\/j.jep.2006.09.041_bib14","doi-asserted-by":"crossref","first-page":"4700","DOI":"10.1021\/jf034374y","article-title":"Fungistatic and bacteriostatic activities of alkamides from Heliopsis longipes roots: affinin and reduced amides","volume":"52","author":"Molina","year":"2004","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"10.1016\/j.jep.2006.09.041_bib15","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1002\/mrc.1459","article-title":"1H and 13C assignments of two new triterpenes from Cladocolea grahami","volume":"42","author":"Rios","year":"2004","journal-title":"Magnetic Resonance in Chemistry"},{"key":"10.1016\/j.jep.2006.09.041_bib16","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S0031-9422(98)00577-9","article-title":"Lignans from Taiwania cryptomerioides","volume":"50","author":"Wang-Hong","year":"1999","journal-title":"Phytochemistry"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874106005010?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874106005010?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T15:41:27Z","timestamp":1628005287000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874106005010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0378874106005010"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2006.09.041","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}