{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T20:49:26Z","timestamp":1790542166766,"version":"4.1.0"},"reference-count":71,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1016\/j.jep.2008.09.017","type":"journal-article","created":{"date-parts":[[2008,9,28]],"date-time":"2008-09-28T04:20:03Z","timestamp":1222575603000},"page":"302-314","source":"Crossref","is-referenced-by-count":110,"title":["Artemisia annua as a self-reliant treatment for malaria in developing countries"],"prefix":"10.1016","volume":"120","author":[{"given":"Sanne","family":"de Ridder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"van der Kooy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Verpoorte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2008.09.017_bib1","doi-asserted-by":"crossref","first-page":"99","DOI":"10.4269\/ajtmh.77.6.suppl.99","article-title":"Patterns of age-specific mortality in children in endemic areas of sub-Saharan Africa","volume":"77","author":"Abdullah","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib2","doi-asserted-by":"crossref","first-page":"771","DOI":"10.4269\/ajtmh.1994.50.771","article-title":"Concentration and time dependency of artemisinin efficacy against Plasmodium falciparum in vitro","volume":"50","author":"Alin","year":"1994","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib3","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1046\/j.1365-2125.1996.35116.x","article-title":"Clinical efficacy and pharmacokinetics of artemisinin monotherapy and in combination with mefloquine in patients with falciparum malaria","volume":"41","author":"Alin","year":"1996","journal-title":"British Journal of Clinical Pharmacology"},{"key":"10.1016\/j.jep.2008.09.017_bib4","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1159\/000109767","article-title":"Antimalarial drug toxicity: a review","volume":"53","author":"AlKadi","year":"2007","journal-title":"Chemotherapy"},{"key":"10.1016\/j.jep.2008.09.017_bib5","doi-asserted-by":"crossref","first-page":"4244","DOI":"10.1021\/jm030181q","article-title":"Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria","volume":"46","author":"Avery","year":"2003","journal-title":"Journal of Medicinal Chemistry."},{"key":"10.1016\/j.jep.2008.09.017_bib6","doi-asserted-by":"crossref","first-page":"4609","DOI":"10.1016\/j.biortech.2007.06.061","article-title":"Yield enhancement strategies for artemisinin production by suspension cultures of Artemisia annua","volume":"99","author":"Baldi","year":"2008","journal-title":"Bioresources Technology"},{"key":"10.1016\/j.jep.2008.09.017_bib7","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0163-7258(01)00140-1","article-title":"Artemisinin and its derivatives: an important new class of antimalarial agents","volume":"90","author":"Balint","year":"2001","journal-title":"Pharmacology & Therapeutics"},{"key":"10.1016\/j.jep.2008.09.017_bib8","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.actatropica.2005.04.014","article-title":"Population biology and antimalarial resistance: The transmission of antimalarial drug resistance in Plasmodium falciparum","volume":"94","author":"Barnes","year":"2005","journal-title":"Acta Tropica"},{"key":"10.1016\/j.jep.2008.09.017_bib9","doi-asserted-by":"crossref","first-page":"714","DOI":"10.2165\/00003495-199550040-00009","article-title":"Artesunate. A review of its pharmacology and therapeutic efficacy in the treatment of malaria","volume":"50","author":"Barradell","year":"1995","journal-title":"Drugs"},{"key":"10.1016\/j.jep.2008.09.017_bib10","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1586\/14787210.5.1.141","article-title":"Treatment of childhood Plasmodium falciparum malaria: current challenges","volume":"5","author":"Bell","year":"2007","journal-title":"Expert Review of Anti-Infective Therapy"},{"key":"10.1016\/j.jep.2008.09.017_bib11","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1038\/nrmicro1525","article-title":"Ensuring quality and access for malaria diagnosis: how can it be achieved?","volume":"4","author":"Bell","year":"2006","journal-title":"Nature Reviews Microbiology"},{"key":"10.1016\/j.jep.2008.09.017_bib12","first-page":"883","article-title":"Screening of Indian plants for biological activity: part XIII","volume":"26","author":"Bhakuni","year":"1988","journal-title":"Indian Journal of Experimental Biology"},{"key":"10.1016\/j.jep.2008.09.017_bib13","first-page":"619","article-title":"Screening of Indian plants for biological activity: part XIV","volume":"28","author":"Bhakuni","year":"1990","journal-title":"Indian Journal of Experimental Biology"},{"key":"10.1016\/j.jep.2008.09.017_bib14","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1258\/td.2007.060184","article-title":"Herba Artemisiae annuae tea preparation compared to sulfadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria in adults: a randomized double-blind clinical trial","volume":"38","author":"Blanke","year":"2008","journal-title":"Tropical Doctor"},{"key":"10.1016\/j.jep.2008.09.017_bib15","doi-asserted-by":"crossref","first-page":"193","DOI":"10.4269\/ajtmh.2007.77.193","article-title":"A major transition in malaria treatment: the adoption and deployment of artemisinin-based combination therapies","volume":"77","author":"Bosman","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib16","series-title":"Encyclopedia of Herbs and Their Uses (RHS)","author":"Bown","year":"1995"},{"key":"10.1016\/j.jep.2008.09.017_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4269\/ajtmh.2004.71.2_suppl.0700001","article-title":"Conquering the intolerable burden of malaria: what's new, what's needed: a summary","volume":"71","author":"Breman","year":"2004","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib18","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4269\/ajtmh.2007.77.88","article-title":"Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control","volume":"77","author":"Brooker","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib19","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1124\/mol.104.009019","article-title":"Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor","volume":"67","author":"Burk","year":"2005","journal-title":"Molecular Pharmacology"},{"key":"10.1016\/j.jep.2008.09.017_bib20","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1128\/CMR.15.4.564-594.2002","article-title":"Evolutionary and historical aspects of the burden of malaria","volume":"15","author":"Carter","year":"2002","journal-title":"Clinical Microbiology Reviews"},{"key":"10.1016\/j.jep.2008.09.017_bib21","unstructured":"CDC (2004). Malaria: geographic distribution, http:\/\/www.cdc.gov\/malaria\/distribution_epi\/distribution.htm."},{"key":"10.1016\/j.jep.2008.09.017_bib22","doi-asserted-by":"crossref","first-page":"825","DOI":"10.4269\/ajtmh.1971.20.825","article-title":"Relapse activity in sporozoite-induced infections with a West African strain of Plasmodium ovale","volume":"20","author":"Chin","year":"1971","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib23","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1128\/CMR.00027-07","article-title":"Plasmodium malariae: parasite and disease","volume":"20","author":"Collins","year":"2007","journal-title":"Clinical Microbiology Reviews"},{"key":"10.1016\/j.jep.2008.09.017_bib24","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1053\/j.spid.2004.05.009","article-title":"Prevention and treatment of malaria in young African children","volume":"15","author":"Crawley","year":"2004","journal-title":"Seminars in Pediatric Infectious Diseases"},{"key":"10.1016\/j.jep.2008.09.017_bib25","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.2174\/0929867013371635","article-title":"The genetics of artemisinin content in Artemisia annua L. and the breeding of high yielding cultivars","volume":"8","author":"Delabays","year":"2001","journal-title":"Current Medicinal Chemistry"},{"key":"10.1016\/j.jep.2008.09.017_bib26","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1475-2875-6-15","article-title":"The safety of artemisinins during pregnancy: a pressing question","volume":"6","author":"Dellicour","year":"2007","journal-title":"Malaria Journal"},{"key":"10.1016\/j.jep.2008.09.017_bib27","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1046\/j.1365-3156.2003.01157.x","article-title":"Adherence to the combination of sulphadoxine\u2013pyrimethamine and artesunate in the Maheba refugee settlement, Zambia","volume":"9","author":"Depoortere","year":"2004","journal-title":"Tropical Medicine & International Health"},{"key":"10.1016\/j.jep.2008.09.017_bib28","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1038\/nature01813","article-title":"Artemisinins target the SERCA of Plasmodium falciparum","volume":"424","author":"Eckstein-Ludwig","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.jep.2008.09.017_bib29","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1055\/s-2007-967138","article-title":"Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin\u2014from bench to bedside","volume":"73","author":"Efferth","year":"2007","journal-title":"Planta Medica"},{"key":"10.1016\/j.jep.2008.09.017_bib30","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1080\/00034983.1997.11813108","article-title":"The chemotherapy of rodent malaria. LIII. \u2018Fenozan B07\u2019 (Fenozan-50F), a difluorinated 3,3\u2032-spirocyclopentane 1,2,4-trioxane: comparison with some compounds of the artemisinin series","volume":"91","author":"Fleck","year":"1997","journal-title":"Annals of Tropical Medicine and Parasitology"},{"key":"10.1016\/j.jep.2008.09.017_bib31","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/j.ijpara.2006.07.011","article-title":"Current perspectives on the mechanism of action of artemisinins","volume":"36","author":"Golenser","year":"2006","journal-title":"International Journal of Parasitology"},{"key":"10.1016\/j.jep.2008.09.017_bib32","doi-asserted-by":"crossref","first-page":"509","DOI":"10.2174\/156802606776743129","article-title":"From artemisinin to new artemisinin antimalarials: biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements","volume":"6","author":"Haynes","year":"2006","journal-title":"Current Topics in Medicinal Chemistry"},{"key":"10.1016\/j.jep.2008.09.017_bib33","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/1475-2875-6-134","article-title":"Impact of home-based management of malaria on health outcomes in Africa: a systematic review of the evidence","volume":"6","author":"Hopkins","year":"2007","journal-title":"Malaria Journal"},{"key":"10.1016\/j.jep.2008.09.017_bib34","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.trstmh.2005.09.020","article-title":"The history of qing hao in the Chinese materia medica","volume":"100","author":"Hsu","year":"2006","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib35","first-page":"744","article-title":"Effect of dihydroartemisinin on the antioxidant capacity of P. falciparum-infected erythrocytes","volume":"34","author":"Ittarat","year":"2003","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"10.1016\/j.jep.2008.09.017_bib36","doi-asserted-by":"crossref","first-page":"3242","DOI":"10.1021\/jo0498765","article-title":"Synthesis of O-aminodihydroartemisinin via TMS triflate catalyzed C\u2013O coupling reaction","volume":"69","author":"Kim","year":"2004","journal-title":"Journal of Organic Chemistry"},{"key":"10.1016\/j.jep.2008.09.017_bib37","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1021\/np060375j","article-title":"Comparative assessment of technologies for extraction of artemisinin","volume":"69","author":"Lapkin","year":"2006","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2008.09.017_bib38","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00253-006-0452-0","article-title":"Artemisinin: current state and perspectives for biotechnological production of an antimalarial drug","volume":"72","author":"Liu","year":"2006","journal-title":"Applied Microbiological Biotechnology"},{"key":"10.1016\/j.jep.2008.09.017_bib39","doi-asserted-by":"crossref","first-page":"112","DOI":"10.4269\/ajtmh.2007.77.112","article-title":"Uncertainty in malaria control in Tanzania: crossroads and challenges for future interventions","volume":"77","author":"Mboera","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib40","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S1473-3099(07)70024-5","article-title":"Reducing the burden of malaria in pregnancy by preventive strategies","volume":"7","author":"Menendez","year":"2007","journal-title":"Lancet Infectious Diseases"},{"key":"10.1016\/j.jep.2008.09.017_bib41","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1128\/MMBR.60.2.301-315.1996","article-title":"Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy","volume":"60","author":"Meshnick","year":"1996","journal-title":"Microbiology Reviews"},{"key":"10.1016\/j.jep.2008.09.017_bib42","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0378-8741(00)00289-0","article-title":"The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects","volume":"73","author":"Mueller","year":"2000","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2008.09.017_bib43","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.trstmh.2003.09.001","article-title":"Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria","volume":"98","author":"Mueller","year":"2004","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib44","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.pt.2007.04.009","article-title":"Plasmodium malariae and Plasmodium ovale\u2014the \u201cbashful\u201d malaria parasites","volume":"23","author":"Mueller","year":"2007","journal-title":"Trends in Parasitology"},{"key":"10.1016\/j.jep.2008.09.017_bib45","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.actatropica.2005.06.009","article-title":"Artemisinin-based combination therapies (ACTs): best hope for malaria treatment but inaccessible to the needy!","volume":"95","author":"Mutabingwa","year":"2005","journal-title":"Acta Tropica"},{"key":"10.1016\/j.jep.2008.09.017_bib46","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1021\/np50045a021","article-title":"Production of artemisinin in tissue cultures of Artemisia annua","volume":"49","author":"Nair","year":"1986","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2008.09.017_bib47","unstructured":"Olumnese, P. 2006. WHO Guidelines for the treatment of malaria."},{"key":"10.1016\/j.jep.2008.09.017_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/00034983.1993.11812733","article-title":"The chemotherapy of rodent malaria. XLVIII. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 1: Studies leading to the development of novel cis-fused cyclopenteno derivatives","volume":"87","author":"Peters","year":"1993","journal-title":"Annals of Tropical Medicine and Parasitology"},{"key":"10.1016\/j.jep.2008.09.017_bib49","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/00034983.1993.11812734","volume":"87","author":"Peters","year":"1993","journal-title":"Annals of Tropical Medicine and Parasitology"},{"key":"10.1016\/j.jep.2008.09.017_bib50","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/00034983.1993.11812745","article-title":"The chemotherapy of rodent malaria. L. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 3: Observations on \u2018Fenozan-50F\u2019, a difluorinated 3,3\u2032-spirocyclopentane 1,2,4-trioxane","volume":"87","author":"Peters","year":"1993","journal-title":"Annals of Tropical Medicine and Parasitology"},{"key":"10.1016\/j.jep.2008.09.017_bib51","doi-asserted-by":"crossref","first-page":"522","DOI":"10.4269\/ajtmh.1994.50.522","article-title":"New, antimalarial, tricyclic 1,2,4-trioxanes: evaluations in mice and monkeys","volume":"50","author":"Posner","year":"1994","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib52","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.actatropica.2003.10.012","article-title":"Therapeutic responses to antimalarial and antibacterial drugs in vivax malaria","volume":"89","author":"Pukrittayakamee","year":"2004","journal-title":"Acta Tropica"},{"key":"10.1016\/j.jep.2008.09.017_bib53","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1007\/s10529-007-9368-8","article-title":"Improvement of artemisinin production by chitosan in hairy root cultures of Artemisia annua L","volume":"29","author":"Putalun","year":"2007","journal-title":"Biotechnology Letters"},{"key":"10.1016\/j.jep.2008.09.017_bib54","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4269\/ajtmh.2004.70.128","article-title":"Pharmacokinetic study of Artemisinin after oral intake of a traditional preparation of Artemisia annua L. (Annual wormwood)","volume":"70","author":"Rath","year":"2004","journal-title":"American Journal for Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib55","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1038\/nature04640","article-title":"Production of the antimalarial drug precursor artemisinic acid in engineered yeast","volume":"440","author":"Ro","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.jep.2008.09.017_bib56","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1021\/ja00341a054","article-title":"Total synthesis of qinghaosu","volume":"105","author":"Schmid","year":"1983","journal-title":"Journal of the American Chemical Society"},{"key":"10.1016\/j.jep.2008.09.017_bib57","first-page":"371","article-title":"Relapse of Plasmodium malariae malaria 20 years after living in an endemic area","volume":"34","author":"Siala","year":"2005","journal-title":"Presse Medical"},{"key":"10.1016\/j.jep.2008.09.017_bib58","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S1471-4922(01)02031-1","article-title":"The past, present and future of childhood malaria mortality in Africa","volume":"17","author":"Snow","year":"2001","journal-title":"Trends in Parasitology"},{"key":"10.1016\/j.jep.2008.09.017_bib59","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1038\/nature03342","article-title":"The global distribution of clinical episodes of Plasmodium falciparum malaria","volume":"434","author":"Snow","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.jep.2008.09.017_bib60","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1002\/bit.10711","article-title":"Scale-up of Artemisia annua L. hairy root cultures produces complex patterns of terpenoid gene expression","volume":"83","author":"Souret","year":"2003","journal-title":"Biotechnology and Bioengineering"},{"key":"10.1016\/j.jep.2008.09.017_bib61","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1080\/14786410310001620556","article-title":"Progress in the research of artemisinin and its analogues as antimalarials: an update","volume":"18","author":"Sriram","year":"2004","journal-title":"Natural Product Research"},{"key":"10.1016\/j.jep.2008.09.017_bib62","doi-asserted-by":"crossref","first-page":"170","DOI":"10.4269\/ajtmh.77.6.suppl.170","article-title":"Intensity of malaria transmission and the spread of Plasmodium falciparum resistant malaria: a review of epidemiologic field evidence","volume":"77","author":"Talisuna","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1016\/j.jep.2008.09.017_bib63","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1111\/j.2042-7158.1990.tb07030.x","article-title":"The pharmacokinetics of artemisinin after oral, intramuscular and rectal administration to volunteers","volume":"42","author":"Titulaer","year":"1990","journal-title":"Journal of Pharmacy and Pharmacology"},{"key":"10.1016\/j.jep.2008.09.017_bib64","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.pt.2004.01.008","article-title":"The Anopheles gambiae genome: next steps for malaria vector control","volume":"20","author":"Toure","year":"2004","journal-title":"Trends in Parasitology"},{"key":"10.1016\/j.jep.2008.09.017_bib65","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1186\/cc2183","article-title":"Clinical review: Severe malaria","volume":"7","author":"Trampuz","year":"2003","journal-title":"Critical Care"},{"key":"10.1016\/j.jep.2008.09.017_bib66","doi-asserted-by":"crossref","first-page":"4670","DOI":"10.1111\/j.1742-4658.2007.05997.x","article-title":"Malaria\u2014an overview","volume":"274","author":"Tuteja","year":"2007","journal-title":"FEBS Journal"},{"key":"10.1016\/j.jep.2008.09.017_bib67","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0165-6147(99)01302-4","article-title":"Artemisinin drugs in the treatment of malaria: from medicinal herb to registered medication","volume":"20","author":"van Agtmael","year":"1999","journal-title":"Trends in Pharmacological Sciences"},{"key":"10.1016\/j.jep.2008.09.017_bib68","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.sajb.2007.10.004","article-title":"Metabolomic quality control of claimed anti-malarial Artemisia afra herbal remedy and A. afra and A. annua plant extracts","volume":"74","author":"Van der Kooy","year":"2008","journal-title":"South African Journal of Botany"},{"key":"10.1016\/j.jep.2008.09.017_bib69","first-page":"381","article-title":"Averting a malaria disaster in Africa\u2014where does the buck stop?","volume":"82","author":"Whitty","year":"2004","journal-title":"Bulletin of the World Health Organisation"},{"key":"10.1016\/j.jep.2008.09.017_bib70","unstructured":"WHO (2008 update). WHO forecast, In: Artepal, the portal of information and orientation on malaria and its treatments with ACT, Bangkok."},{"key":"10.1016\/j.jep.2008.09.017_bib71","doi-asserted-by":"crossref","first-page":"179","DOI":"10.4269\/ajtmh.2004.71.179","article-title":"Antimalarial drug resistance, artemisinin-based combination therapy, and the contribution of modeling to elucidating policy choices","volume":"71","author":"Yeung","year":"2004","journal-title":"American Journal of Tropical Medicine and Hygiene"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874108005011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874108005011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T07:55:28Z","timestamp":1631865328000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874108005011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":71,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["S0378874108005011"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2008.09.017","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2008,12]]}}}