{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T04:26:56Z","timestamp":1783398416959,"version":"3.54.6"},"reference-count":31,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.jep.2011.04.056","type":"journal-article","created":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T01:57:26Z","timestamp":1304215046000},"page":"204-209","source":"Crossref","is-referenced-by-count":38,"title":["Cytotoxic and genotoxic effects of defence secretion of Ulomoides dermestoides on A549 cells"],"prefix":"10.1016","volume":"136","author":[{"given":"Rosana","family":"Crespo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Luciana","family":"Villaverde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan R.","family":"Girotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alba","family":"G\u00fcerci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Patricia","family":"Ju\u00e1rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarita G.","family":"de Bravo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2011.04.056_bib0005","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/BF00994202","article-title":"Defensive secretion of Tenebrio molitor (Coleoptera: Tenebrionidae)","volume":"17","author":"Attygalle","year":"1991","journal-title":"Journal of Chemical Ecology"},{"key":"10.1016\/j.jep.2011.04.056_bib0010","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1021\/np50100a007","article-title":"Defensive secretion of the millipede Floridobolus penneri","volume":"56","author":"Attygalle","year":"1993","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2011.04.056_bib0015","series-title":"Chemical Defenses of Arthropods","author":"Blum","year":"1981"},{"key":"10.1016\/j.jep.2011.04.056_bib0020","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1021\/tx9902082","article-title":"Role of quinones in toxicology","volume":"13","author":"Bolton","year":"2000","journal-title":"Chemical Research in Toxicology"},{"key":"10.1016\/j.jep.2011.04.056_bib0025","series-title":"Entomologia did\u00e1tica","author":"Buzzi","year":"1999"},{"key":"10.1016\/j.jep.2011.04.056_bib0030","first-page":"422","article-title":"Beetle-eating: a Malaysia folk medical practice and its public health implications","volume":"29","author":"Chu","year":"1977","journal-title":"Tropical and Geographical Medicine"},{"key":"10.1016\/j.jep.2011.04.056_bib0035","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1023\/A:1015696830997","article-title":"The use of insects in folk medicine in the state of Bahia, northeastern Brazil, with notes on insects reported elsewhere in Brazilian folk medicine","volume":"30","author":"Costa-Neto","year":"2002","journal-title":"Human Ecology"},{"key":"10.1016\/j.jep.2011.04.056_bib0040","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1073\/pnas.95.3.1108","article-title":"Rendering the inedible edible: circumvention of a millipede's chemical defense by a predaceous beetle larva (Phengodidae)","volume":"95","author":"Eisner","year":"1998","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.jep.2011.04.056_bib0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/1098-2280(2001)37:1<1::AID-EM1000>3.0.CO;2-1","article-title":"Influence of culture conditions on the DNA-damaging effect of benzene and its metabolites in human peripheral blood mononuclear cells","volume":"37","author":"Fabiani","year":"2001","journal-title":"Environmental and Molecular Mutagenesis"},{"key":"10.1016\/j.jep.2011.04.056_bib0050","first-page":"48","article-title":"First record of the oriental species of Ulomoides dermestoides (Coleoptera: Tenebrionidae) in Argentina","volume":"61","author":"Flores","year":"2002","journal-title":"Revista de la Sociedad Entomol\u00f3gica Argentina"},{"key":"10.1016\/j.jep.2011.04.056_bib0055","first-page":"19","article-title":"Evaluaci\u00f3n citomolecular del efecto vecindad en fibroblastos de pulm\u00f3n humano bajo condiciones de exposici\u00f3n radioterap\u00e9utica","volume":"9","author":"G\u00fcerci","year":"2008","journal-title":"Revista de F\u00edsica M\u00e9dica"},{"key":"10.1016\/j.jep.2011.04.056_bib0060","first-page":"5172","article-title":"Oxidative DNA damage and apoptosis induced by benzene metabolites","volume":"56","author":"Hiraku","year":"1996","journal-title":"Cancer Research"},{"key":"10.1016\/j.jep.2011.04.056_bib0065","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1289\/ehp.961041265","article-title":"Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene","volume":"104","author":"Hutt","year":"1996","journal-title":"Environmental Health Perspectives"},{"key":"10.1016\/j.jep.2011.04.056_bib0070","doi-asserted-by":"crossref","first-page":"425","DOI":"10.2174\/1389200023337388","article-title":"The metabolism and toxicity of quinones, quinoneimines, quinone methides, and quinone-thioethers","volume":"3","author":"Monks","year":"2002","journal-title":"Current Drug Metabolism"},{"key":"10.1016\/j.jep.2011.04.056_bib0075","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"The Journal of Immunological Methods"},{"key":"10.1016\/j.jep.2011.04.056_bib0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0009-2797(91)90029-7","article-title":"Molecular mechanisms of quinone cytotoxicity","volume":"80","author":"O\u2019Brien","year":"1991","journal-title":"Chemico-Biological Interactions"},{"key":"10.1016\/j.jep.2011.04.056_bib0085","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.mrfmmm.2008.11.006","article-title":"In silico studies with human DNA topoisomerase-II alpha to unravel the mechanism of in vitro genotoxicity of benzene and its metabolites","volume":"661","author":"Pandey","year":"2009","journal-title":"Mutation Research"},{"key":"10.1016\/j.jep.2011.04.056_bib0090","series-title":"Tissue Culture: Methods and Applications","first-page":"406","article-title":"Dye exclusion tests for cell viability","author":"Phillips","year":"1973"},{"key":"10.1016\/j.jep.2011.04.056_bib0095","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1093\/carcin\/11.9.1469","article-title":"Detection of (30-hydroxy)-3 N4-benzetheno-20-deoxycytidine-30-phosphate by 32P-postlabeling of DNA reacted with p-benzoquinone","volume":"11","author":"Pongracz","year":"1990","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.jep.2011.04.056_bib0100","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.tox.2004.12.035","article-title":"Benzoquinone activates the ERK\/MAPK signaling pathway via ROS production in HL-60 cells","volume":"209","author":"Ruiz-Ramos","year":"2005","journal-title":"Toxicology"},{"key":"10.1016\/j.jep.2011.04.056_bib0105","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s10753-009-9171-x","article-title":"Anti-inflammatory and immunomodulatory effects of Ulomoides dermestoides on induced pleurisy in rats and lymphoproliferation","volume":"33","author":"Santos","year":"2009","journal-title":"In Vitro Inflammation"},{"key":"10.1016\/j.jep.2011.04.056_bib0110","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1177\/096032719601500510","article-title":"Benzene metabolites enhance reactive oxygen species generation in HL-60 human leukemia cells","volume":"15","author":"Shen","year":"1996","journal-title":"Human and Experimental Toxicology"},{"key":"10.1016\/j.jep.2011.04.056_bib0115","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/0014-4827(88)90265-0","article-title":"A simple technique for quantitation of low levels of DNA damage in individual cells","volume":"175","author":"Singh","year":"1988","journal-title":"Experimental Cell Research"},{"key":"10.1016\/j.jep.2011.04.056_bib0120","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1093\/toxsci\/kfh182","article-title":"Application of quantitative structure-toxicity relationships for the comparison of the cytotoxicity of 14 p-Benzoquinone congeners in primary cultured rat hepatocytes versus PC12 cells","volume":"81","author":"Siraki","year":"2004","journal-title":"Toxicological Sciences"},{"key":"10.1016\/j.jep.2011.04.056_bib0125","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/(SICI)1098-2280(2000)35:3<206::AID-EM8>3.0.CO;2-J","article-title":"Single cell gel\/comet assay: guidelines for in vitro and in vivo genetic toxicology testing","volume":"35","author":"Tice","year":"2000","journal-title":"Environmental and Molecular Mutagenesis"},{"key":"10.1016\/j.jep.2011.04.056_bib0130","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.cbpb.2009.08.001","article-title":"Volatile secretions and epicuticular hydrocarbons of the beetle Ulomoides dermestoides","volume":"154","author":"Villaverde","year":"2009","journal-title":"Comparative Biochemistry and Physiology Part B"},{"key":"10.1016\/j.jep.2011.04.056_bib0135","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jep.2005.12.007","article-title":"Pharmacologically active natural products in the defence secretion of Palembus ocularis (Tenebrionidae, Coleoptera)","volume":"106","author":"Wahrendorf","year":"2006","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2011.04.056_bib0140","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/10715769900300101","article-title":"Enhancement of myeloid cell growth by benzene metabolites via the production of active oxygen species","volume":"30","author":"Wiemels","year":"1999","journal-title":"Free Radical Research"},{"key":"10.1016\/j.jep.2011.04.056_bib0145","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/toxsci\/kfg008","article-title":"Homologous recombination initiated by benzene metabolites: a potential role of oxidative stress","volume":"72","author":"Winn","year":"2003","journal-title":"Toxicological Sciences"},{"key":"10.1016\/j.jep.2011.04.056_bib0150","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0305-0491(78)90207-9","article-title":"Concentrations of substitued p-benzoquinones and 1-pentadecene in the flour beetles Tribolium confusum (J. du Val) and Tribolium castaneum (Herbst)","volume":"61","author":"Wirtz","year":"1978","journal-title":"Comparative Biochemistry and Physiology Part B"},{"key":"10.1016\/j.jep.2011.04.056_bib0155","first-page":"437","article-title":"The toxicity of benzene and its metabolism and molecular pathology in human risk assessment","volume":"48","author":"Yardley-Jones","year":"1991","journal-title":"British Journal of Industrial Medicine"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874111003084?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874111003084?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T03:53:33Z","timestamp":1543809213000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874111003084"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0378874111003084"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2011.04.056","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}