{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:05:27Z","timestamp":1790874327197,"version":"4.1.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Chinese National Science and Technology Pillar Program","award":["2006BAI04A07"],"award-info":[{"award-number":["2006BAI04A07"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.jep.2011.12.009","type":"journal-article","created":{"date-parts":[[2011,12,13]],"date-time":"2011-12-13T18:24:50Z","timestamp":1323800690000},"page":"757-764","source":"Crossref","is-referenced-by-count":66,"title":["Optimized project of traditional Chinese medicine in treating chronic kidney disease stage 3: A multicenter double-blinded randomized controlled trial"],"prefix":"10.1016","volume":"139","author":[{"given":"Yong-jun","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-qun","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-qin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-qing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian-bo","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-li","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ni-zhi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-zhen","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-juan","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fa-Huan","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xusheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2011.12.009_bib0005","doi-asserted-by":"crossref","first-page":"463","DOI":"10.2165\/00044011-199816060-00006","article-title":"Protection of renal function with ACE inhibitors. Experience with benazepril","volume":"16","author":"Aldigier","year":"1998","journal-title":"Clinical Drug Investigation"},{"key":"10.1016\/j.jep.2011.12.009_bib0010","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1159\/000272937","article-title":"Effect of chronic kidney disease and comorbid conditions on health care costs: a 10-year observational study in a general population","volume":"31","author":"Baumeister","year":"2009","journal-title":"American Journal of Nephrology"},{"key":"10.1016\/j.jep.2011.12.009_bib0015","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1745-6215-11-27","article-title":"JinQi-Jiangtang tablet, a Chinese patent medicine, for pre-diabetes: a randomized controlled trial","volume":"11","author":"Cao","year":"2010","journal-title":"Trials"},{"key":"10.1016\/j.jep.2011.12.009_bib0020","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1046\/j.1523-1755.2003.00113.x","article-title":"Emodin ameliorates glucose-induced matrix synthesis in human peritoneal mesothelial cells","volume":"64","author":"Chan","year":"2003","journal-title":"Kidney International"},{"key":"10.1016\/j.jep.2011.12.009_bib0025","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1093\/ndt\/gfn767","article-title":"Community-based study on CKD subjects and the associated risk factors","volume":"24","author":"Chen","year":"2009","journal-title":"Nephrology, Dialysis, Transplantation"},{"key":"10.1016\/j.jep.2011.12.009_bib0030","first-page":"101","article-title":"Multicentered, randomized, controlled clinical trial on patients with IgA nephropathy of Qi-yin deficiency syndrome type","volume":"27","author":"Chen","year":"2007","journal-title":"Chinese Journal of Integrative Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0035","first-page":"1061","article-title":"Prospective, multi-centered, randomized and controlled trial on effect of Shenle capsule in treating patients with IgA nephropathy of Fei-Pi Qi-deficiency syndrome","volume":"26","author":"Chen","year":"2006","journal-title":"Chinese Journal of Integrative Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0040","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.molimm.2005.07.026","article-title":"Triptolide inhibits B7-H1 expression on proinflammatory factor activated renal tubular epithelial cells by decreasing NF-kappaB transcription","volume":"43","author":"Chen","year":"2006","journal-title":"Molecular Immunology"},{"key":"10.1016\/j.jep.2011.12.009_bib0045","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1038\/ki.2010.41","article-title":"Triptolide reduces proteinuria in experimental membranous nephropathy and protects against C5b-9-induced podocyte injury in vitro","volume":"77","author":"Chen","year":"2010","journal-title":"Kidney International"},{"key":"10.1016\/j.jep.2011.12.009_bib0050","first-page":"47","article-title":"Current burden of ESRD in China and it is estimated to be increasing faster in the near future","volume":"9","author":"Chinese Society of Blood Purification","year":"2010","journal-title":"Chinese Journal of Blood Purification"},{"key":"10.1016\/j.jep.2011.12.009_bib0055","first-page":"77","article-title":"The report about the registration of dialysis and transplantation in China 1999","volume":"17","author":"Dialysis and Transplantation Registration Group","year":"2002","journal-title":"Chinese Journal of Nephrology"},{"key":"10.1016\/j.jep.2011.12.009_bib0060","first-page":"656","article-title":"Therapeutic effect of total glucosides of paeony on lupus nephritis in MRL\/lpr mice","volume":"31","author":"Ding","year":"2011","journal-title":"Nan Fang Yi Ke Da Xue Xue Bao"},{"key":"10.1016\/j.jep.2011.12.009_bib0065","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/S0272-6386(99)70431-2","article-title":"Erythropoietin deficiency in hyporeninemia","volume":"33","author":"Donnelly","year":"1999","journal-title":"American Journal of Kidney Diseases"},{"key":"10.1016\/j.jep.2011.12.009_bib0070","first-page":"939","article-title":"Mechanism of Chinese herbal medicine delaying progression of chronic kidney disease","volume":"34","author":"Dou","year":"2009","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"key":"10.1016\/j.jep.2011.12.009_bib0075","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.imlet.2008.10.001","article-title":"Tetrandrine protects mice from concanavalin A-induced hepatitis through inhibiting NF-kappaB activation","volume":"121","author":"Feng","year":"2008","journal-title":"Immunology Letters"},{"key":"10.1016\/j.jep.2011.12.009_bib0080","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1080\/08860220903001879","article-title":"A mildly altered vascular homeostasis in early stage of CKD","volume":"31","author":"Futrakul","year":"2009","journal-title":"Renal Failure"},{"key":"10.1016\/j.jep.2011.12.009_bib0085","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1055\/s-2006-947186","article-title":"A Chinese herbal decoction, Danggui Buxue Tang, prepared from Radix Astragali and Radix Angelicae Sinensis stimulates the immune responses","volume":"72","author":"Gao","year":"2006","journal-title":"Planta Medica"},{"key":"10.1016\/j.jep.2011.12.009_bib0090","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1142\/S0192415X09006795","article-title":"Antioxidant effect of tianwang buxin pills a traditional Chinese medicine formula: double-blind, randomized controlled trial","volume":"37","author":"Gim","year":"2009","journal-title":"American Journal of Chinese Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0095","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s10620-006-9321-z","article-title":"Inhibitory effect of emodin on tissue inhibitor of metalloproteinases-1 (TIMP-1) expression in rat hepatic stellate cells","volume":"52","author":"Gui","year":"2007","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1016\/j.jep.2011.12.009_bib0100","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1254\/jjp.59.159","article-title":"Studies on the antinephritic effect of plant components (4): reduction of protein excretion by berberine and coptisine in rats with original-type anti-GBM nephritis","volume":"59","author":"Hattori","year":"1992","journal-title":"Japanese Journal of Pharmacology"},{"key":"10.1016\/j.jep.2011.12.009_bib0105","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.vph.2010.03.002","article-title":"Emodin and rhein inhibit LIGHT-induced monocytes migration by blocking of ROS production","volume":"53","author":"Heo","year":"2010","journal-title":"Vascular Pharmacology"},{"key":"10.1016\/j.jep.2011.12.009_bib0110","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1681\/ASN.2006121372","article-title":"Renoprotection of optimal antiproteinuric doses (ROAD) study: a randomized controlled study of benazepril and losartan in chronic renal insufficiency","volume":"18","author":"Hou","year":"2007","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1016\/j.jep.2011.12.009_bib0115","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1056\/NEJMoa053107","article-title":"Efficacy and safety of benazepril for advanced chronic renal insufficiency","volume":"354","author":"Hou","year":"2006","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0120","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1093\/ndt\/gfp245","article-title":"In vitro anti-fibrotic activities of herbal compounds and herbs","volume":"24","author":"Hu","year":"2009","journal-title":"Nephrology, Dialysis, Transplantation"},{"key":"10.1016\/j.jep.2011.12.009_bib0125","first-page":"1324","article-title":"Effects of Radix Astragali and Fructus Corni on urinary protein pattern in nephropathy mice by microfluidic chip","volume":"32","author":"Huang","year":"2007","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"key":"10.1016\/j.jep.2011.12.009_bib0130","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/ajh.2007.53","article-title":"Effects of the Renin\u2013Angiotensin system blockade on hemoglobin levels in type 2 diabetic patients with chronic kidney disease","volume":"21","author":"Inoue","year":"2008","journal-title":"American Journal of Hypertension"},{"key":"10.1016\/j.jep.2011.12.009_bib0135","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1016\/j.lfs.2004.02.034","article-title":"Lithospermic acid B isolated from Salvia miltiorrhiza ameliorates ischemia\/reperfusion-induced renal injury in rats","volume":"75","author":"Kang","year":"2004","journal-title":"Life Sciences"},{"key":"10.1016\/j.jep.2011.12.009_bib0140","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1155\/S0962935196000415","article-title":"Anti-inflammatory effects of Stephania tetrandra S. Moore on interleukin-6 production and experimental inflammatory disease models","volume":"5","author":"Kang","year":"1996","journal-title":"Mediators of Inflammation"},{"key":"10.1016\/j.jep.2011.12.009_bib0145","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1248\/bpb.32.220","article-title":"Protective effect of Tanshinone IIA on the early stage of experimental diabetic nephropathy","volume":"32","author":"Kim","year":"2009","journal-title":"Biological and Pharmaceutical Bulletin"},{"key":"10.1016\/j.jep.2011.12.009_bib0150","first-page":"1093","article-title":"Immunomodulatory effects and mechanisms of plant alkaloid tetrandrine in autoimmune diseases","volume":"23","author":"Lai","year":"2002","journal-title":"Acta Pharmacologica Sinica"},{"key":"10.1016\/j.jep.2011.12.009_bib0155","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-130-6-199903160-00002","article-title":"A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of diet in renal disease study group","volume":"130","author":"Levey","year":"1999","journal-title":"Annals of Internal Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0160","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1111\/j.1745-7254.2006.00378.x","article-title":"Comparison of antioxidant activities between salvianolic acid B and Ginkgo biloba extract (EGb 761)","volume":"27","author":"Liu","year":"2006","journal-title":"Acta Pharmacologica Sinica"},{"key":"10.1016\/j.jep.2011.12.009_bib0165","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0162-3109(99)00189-7","article-title":"Suppression of experimental autoimmune tubulointerstitial nephritis in BALB\/c mice by berberine","volume":"48","author":"Marinova","year":"2000","journal-title":"Immunopharmacology"},{"key":"10.1016\/j.jep.2011.12.009_bib0170","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1142\/S0192415X05003089","article-title":"The nephroprotective effects of the herbal medicine preparation, WH30+, on the chemical-induced acute and chronic renal failure in rats","volume":"33","author":"Ngai","year":"2005","journal-title":"American Journal of Chinese Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0175","doi-asserted-by":"crossref","first-page":"44","DOI":"10.47102\/annals-acadmedsg.V34N1p44","article-title":"Herbal treatment for renal diseases","volume":"34","author":"Peng","year":"2005","journal-title":"Annals of the Academy of Medicine, Singapore"},{"key":"10.1016\/j.jep.2011.12.009_bib0180","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.3736\/jcim20091109","article-title":"Effects of No.2 Renal Failure Recipe on expressions of cyclooxygenase-2 and -1 mRNAs in rats with chronic renal failure","volume":"7","author":"Pu","year":"2009","journal-title":"Zhong Xi Yi Jie He Xue Bao"},{"key":"10.1016\/j.jep.2011.12.009_bib0185","first-page":"1216","article-title":"Effect of Qufengtongluo recipe on expression of nephrin mRNA in adriamycin-induced nephropathy in rats","volume":"34","author":"Ren","year":"2009","journal-title":"Zhong Nan Da Xue Xue Bao Yi Xue Ban"},{"key":"10.1016\/j.jep.2011.12.009_bib0190","first-page":"759","article-title":"The protective effects of Salvia miltiorrhiza on the warm ischemic kidney: experimental study in animals","volume":"26","author":"Shen","year":"1988","journal-title":"Zhonghua Wai Ke Za Zhi"},{"key":"10.1016\/j.jep.2011.12.009_bib0195","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2169\/internalmedicine.45.1515","article-title":"A five-year comparison of the renal protective effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients with non-diabetic nephropathy","volume":"45","author":"Shoda","year":"2006","journal-title":"Internal Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0200","first-page":"1471","article-title":"The suggestions and researches on the determination of assessing sheet for the evaluation of traditional Chinese medicine syndrome patterns","volume":"16","author":"Song","year":"2007","journal-title":"Modern Journal of Integrated Traditional Chinese and Western Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0205","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.colsurfb.2006.02.014","article-title":"Effect of water deficits on the activity of anti-oxidative enzymes and osmoregulation among three different genotypes of Radix Astragali at seeding stage","volume":"49","author":"Tan","year":"2006","journal-title":"Colloids and Surfaces B: Biointerfaces"},{"key":"10.1016\/j.jep.2011.12.009_bib0210","doi-asserted-by":"crossref","first-page":"378","DOI":"10.3748\/wjg.v13.i3.378","article-title":"Effect of emodin on pancreatic fibrosis in rats","volume":"13","author":"Wang","year":"2007","journal-title":"World Journal of Gastroenterology"},{"key":"10.1016\/j.jep.2011.12.009_bib0215","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.ejphar.2006.08.087","article-title":"Inhibition of phosphorylation of p38 MAPK involved in the protection of nephropathy by emodin in diabetic rats","volume":"553","author":"Wang","year":"2006","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.jep.2011.12.009_bib0220","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jep.2009.04.018","article-title":"Assessment of the renal protection and hepatotoxicity of rhubarb extract in rats","volume":"124","author":"Wang","year":"2009","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2011.12.009_bib0225","series-title":"The Basic Theories of Traditional Chinese Medicine","first-page":"22","author":"Wang","year":"2001"},{"key":"10.1016\/j.jep.2011.12.009_bib0230","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1053\/j.ajkd.2009.12.011","volume":"55","author":"White","year":"2010","journal-title":"American Journal of Kidney Diseases"},{"key":"10.1016\/j.jep.2011.12.009_bib0235","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/s11655-008-0098-0","article-title":"Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure","volume":"14","author":"Wu","year":"2008","journal-title":"Chinese Journal of Integrative Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0240","first-page":"1198","article-title":"Mechanism of the effect of Tongluo Recipe against glomerular sclerosis in rats","volume":"28","author":"Wu","year":"2008","journal-title":"Nan Fang Yi Ke Da Xue Xue Bao"},{"key":"10.1016\/j.jep.2011.12.009_bib0245","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1745-7254.2008.00734.x","article-title":"Tetrandrine suppresses lipopolysaccharide-induced microglial activation by inhibiting NF-kappaB pathway","volume":"29","author":"Xue","year":"2008","journal-title":"Acta Pharmacologica Sinica"},{"key":"10.1016\/j.jep.2011.12.009_bib0250","doi-asserted-by":"crossref","first-page":"7177","DOI":"10.1021\/jf071242m","article-title":"Nonenzymatic antioxidative and antiglycative effects of oleanolic acid and ursolic acid","volume":"55","author":"Yin","year":"2007","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"10.1016\/j.jep.2011.12.009_bib0255","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0944-7113(00)80022-7","article-title":"Role of Salviae Miltiorrhizae Radix extract and its compounds in enhancing nitric oxide expression","volume":"7","author":"Yokozawa","year":"2000","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0260","first-page":"2400","article-title":"Effects of Salvia miltiorrhiza on TGF-beta1, ROS and PAI-1 induced by angiotensin II in renal mesangial cells","volume":"32","author":"Yuan","year":"2007","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"key":"10.1016\/j.jep.2011.12.009_bib0265","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1142\/S0192415X08006405","article-title":"Salvia miltiorrhiza depresses plasminogen activator inhibitor-1 production through inhibition of angiotensin II","volume":"36","author":"Yuan","year":"2008","journal-title":"American Journal of Chinese Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0270","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jep.2005.12.026","article-title":"Danshen prevents the occurrence of oxidative stress in the eye and aorta of diabetic rats without affecting the hyperglycemic state","volume":"106","author":"Yue","year":"2006","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2011.12.009_bib0275","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.jep.2008.09.024","article-title":"Molecular pharmacological basis of the YiSui ShenXu Granule in beta-thalassemia therapy","volume":"120","author":"Zhang","year":"2008","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2011.12.009_bib0280","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1053\/j.ajkd.2007.03.011","article-title":"Association between carotid artery intima-media thickness and early-stage CKD in a Chinese population","volume":"49","author":"Zhang","year":"2007","journal-title":"American Journal of Kidney Diseases"},{"key":"10.1016\/j.jep.2011.12.009_bib0285","first-page":"330","article-title":"The Progress in the Research of TCM syndrome patterns in Chronic Renal Failure Zhejiang","volume":"20","author":"Zhen","year":"2010","journal-title":"Journal of Integrated Traditional Chinese and Western Medicine"},{"key":"10.1016\/j.jep.2011.12.009_bib0290","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/ki.2008.203","article-title":"Triptolide protects podocytes from puromycin aminonucleoside induced injury in vivo and in vitro","volume":"74","author":"Zheng","year":"2008","journal-title":"Kidney International"},{"key":"10.1016\/j.jep.2011.12.009_bib0295","first-page":"505","article-title":"Emodin inhibits extracellular matrix synthesis by suppressing p38 and ERK1\/2 pathways in TGF-beta1-stimulated NRK-49F cells","volume":"4","author":"Zhu","year":"2011","journal-title":"Molecular Medicine Report"},{"key":"10.1016\/j.jep.2011.12.009_bib0300","doi-asserted-by":"crossref","first-page":"3180","DOI":"10.1093\/ndt\/gfq239","article-title":"Triptolide inhibits extracellular matrix protein synthesis by suppressing the Smad2 but not the MAPK pathway in TGF-beta1-stimulated NRK-49F cells","volume":"25","author":"Zhu","year":"2010","journal-title":"Nephrology, Dialysis, Transplantation"},{"key":"10.1016\/j.jep.2011.12.009_bib0305","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1631\/jzus.B0820230","article-title":"Astragalus mongholicus ameliorates renal fibrosis by modulating HGF and TGF-beta in rats with unilateral ureteral obstruction","volume":"10","author":"Zuo","year":"2009","journal-title":"Journal of Zhejiang University Science B"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874111008762?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874111008762?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T20:27:46Z","timestamp":1713212866000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874111008762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":61,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0378874111008762"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2011.12.009","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]}}}