{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:24:30Z","timestamp":1788870270559,"version":"build-2803163510"},"reference-count":70,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"DST-PURSE","award":["RPO\/DST\/PURSE\/CONSUMABLES\/2010\/790"],"award-info":[{"award-number":["RPO\/DST\/PURSE\/CONSUMABLES\/2010\/790"]}]},{"name":"University of Madras and University Grant Commission (UGC)","award":["33-380\/2007 SR"],"award-info":[{"award-number":["33-380\/2007 SR"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.jep.2012.10.030","type":"journal-article","created":{"date-parts":[[2012,10,25]],"date-time":"2012-10-25T22:50:43Z","timestamp":1351205443000},"page":"32-41","source":"Crossref","is-referenced-by-count":54,"title":["Effect of Mucuna pruriens (Linn.) on mitochondrial dysfunction and DNA damage in epididymal sperm of streptozotocin induced diabetic rat"],"prefix":"10.1016","volume":"145","author":[{"given":"Sekar","family":"Suresh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elumalai","family":"Prithiviraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagella","family":"Venkata Lakshmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohanraj","family":"Karthik Ganesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmanan","family":"Ganesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seppan","family":"Prakash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2012.10.030_bib201","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.foodchem.2004.01.084","article-title":"Variability in the physicochemical, nutritional and antinutritional attributes of six Mucuna species","volume":"89","author":"Adebowale","year":"2005","journal-title":"Food Chemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib1","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1093\/humrep\/dem077","article-title":"Insulin dependent diabetes mellitus: implications for male reproductive function","volume":"22","author":"Agbaje","year":"2007","journal-title":"Human Reproduction"},{"key":"10.1016\/j.jep.2012.10.030_bib2","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1002\/(SICI)1098-2795(199708)47:4<468::AID-MRD14>3.0.CO;2-S","article-title":"Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine","volume":"47","author":"Aitken","year":"1997","journal-title":"Molecular Reproduction and Development"},{"key":"10.1016\/j.jep.2012.10.030_bib3","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1016\/j.theriogenology.2006.06.006","article-title":"Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes","volume":"66","author":"Amaral","year":"2006","journal-title":"Theriogenology"},{"key":"10.1016\/j.jep.2012.10.030_bib202","first-page":"53","article-title":"Sexual function improving effect of Mucuna pruriens in sexually normal male rats","volume":"67","author":"Amin","year":"1996","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jep.2012.10.030_bib4","doi-asserted-by":"crossref","first-page":"46","DOI":"10.2174\/157339908783502398","article-title":"Diabetes and the impairment of reproductive function: possible role of mitochondria and reactive oxygen species","volume":"4","author":"Amaral","year":"2008","journal-title":"Current Diabetes Reviews"},{"key":"10.1016\/j.jep.2012.10.030_bib5","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.reprotox.2005.05.003","article-title":"Protective role of lycopene on cisplatin-induced changes in sperm characteristics, testicular damage and oxidative stress in rats","volume":"21","author":"Atessahin","year":"2006","journal-title":"Reproductive Toxicology"},{"key":"10.1016\/j.jep.2012.10.030_bib6","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1016\/j.fertnstert.2007.09.007","article-title":"Sperm nuclear DNA fragmentation and mitochondrial activity in men with varicocele","volume":"90","author":"Blumer","year":"2008","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.jep.2012.10.030_bib7","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1006\/bbrc.1993.1365","article-title":"Enzymatic basis for altered ascorbicacid and dehydroascorbic acid levels in diabetes","volume":"191","author":"Bode","year":"1993","journal-title":"Biochemistry Biophysics Research Communication"},{"key":"10.1016\/j.jep.2012.10.030_bib8","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1038\/414813a","article-title":"Biochemistry and molecular cell biology of diabetic complications","volume":"414","author":"Brownlee","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.jep.2012.10.030_bib9","first-page":"E881","article-title":"Sustained hyperglycemia results in testicular dysfunction and reduced fertility potential in BBWOR diabetic rats","volume":"259","author":"Cameron","year":"1990","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.jep.2012.10.030_bib10","unstructured":"Canadian Council for Animal Care Guide to the Care and Use of Experimental Animals 1993 vol. 1, Ed. 2. Olfert, E.D., Cross, B.M., McWilliam, A.A. (Eds), Ottawa, Canada."},{"key":"10.1016\/j.jep.2012.10.030_bib11","first-page":"257","article-title":"Committee for the purpose of control and supervision on experiments on animals","volume":"35","author":"Committee for the Purpose of Control and Supervision on Experiments on Animals CPCSEA Guidelines for Laboratory Animal Facility","year":"2003","journal-title":"Indian Journal of Pharmacology"},{"key":"10.1016\/j.jep.2012.10.030_bib12","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1038\/aja.2010.97","article-title":"The epididymis, cytoplasmic droplets and male fertility","volume":"13","author":"Cooper","year":"2011","journal-title":"Asian Journal Andrology"},{"key":"10.1016\/j.jep.2012.10.030_bib13","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0076-6879(84)05019-9","article-title":"Vitamin E analysis methods for animal tissue","volume":"105","author":"Desai","year":"1984","journal-title":"Methods in Enzymology"},{"key":"10.1016\/j.jep.2012.10.030_bib14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/j.1939-4640.2001.tb02152.x","article-title":"Comparative study of cytochemical tests for sperm chromatin integrity","volume":"22","author":"Erenpreiss","year":"2001","journal-title":"Journal of Andrology"},{"key":"10.1016\/j.jep.2012.10.030_bib15","first-page":"412","article-title":"Biology of disease-free radicals and tissue injury","volume":"47","author":"Freeman","year":"1982","journal-title":"Laboratory Investigation"},{"key":"10.1016\/j.jep.2012.10.030_bib16","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/j.1939-4640.1996.tb01783.x","article-title":"Development of an image analysis system to monitor the retention of residual cytoplasm by human spermatozoa: correlation with biochemical markers of the cytoplasmic space, oxidative stress, and sperm function","volume":"17","author":"Gomez","year":"1996","journal-title":"Journal of Andrology"},{"key":"10.1016\/j.jep.2012.10.030_bib17","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/sj.cdd.4401231","article-title":"Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis","volume":"10","author":"Gottlieb","year":"2003","journal-title":"Cell Death and Differentiation"},{"key":"10.1016\/j.jep.2012.10.030_bib18","series-title":"Phytochemical Methods. A Guide to Modern Techniques of Plant Analysis","author":"Harborne","year":"1973"},{"key":"10.1016\/j.jep.2012.10.030_bib19","doi-asserted-by":"crossref","first-page":"7130","DOI":"10.1016\/S0021-9258(19)42083-8","article-title":"Glutathione-S-transferase. The first enzymatic step in mercapturic formation","volume":"249","author":"Habig","year":"1973","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib20","first-page":"723","article-title":"Comparative biochemical studies of human seminal plasma from normospermic, oligospermic, asthenospermic and azoospermic men","volume":"60","author":"Hafez","year":"1977","journal-title":"Journal of Egyptian Medical Association"},{"key":"10.1016\/j.jep.2012.10.030_bib21","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1042\/BJ20061209","article-title":"Ca2+, NAD(P)H and membrane potential changes in pancreatic \u03b2-cells by methyl succinate: comparison with glucose","volume":"403","author":"Heart","year":"2007","journal-title":"Biochemical Journal"},{"key":"10.1016\/j.jep.2012.10.030_bib22","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/molehr\/2.8.613","article-title":"A comparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men, using a modified comet assay","volume":"2","author":"Hughes","year":"1996","journal-title":"Molecular Human Reproduction"},{"key":"10.1016\/j.jep.2012.10.030_bib23","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0015-0282(16)43999-3","article-title":"Peroxidative breakdown of phospholipids in human spermatozoa: spermicidal effects of fatty acid peroxides and protective action of seminal plasma","volume":"31","author":"Jones","year":"1979","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.jep.2012.10.030_bib24","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1042\/bj3040219","article-title":"DNA cleavage induced by glycation of Cu, Zn-superoxide dismutase","volume":"304","author":"Kaneto","year":"1994","journal-title":"Biochemistry Journal"},{"key":"10.1016\/j.jep.2012.10.030_bib25","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/S0891-5849(02)01010-9","article-title":"Impaired ascorbic acid metabolism in streptozotocin-induced diabetic rats","volume":"33","author":"Kashiba","year":"2002","journal-title":"Free Radical Biology and Medicine"},{"key":"10.1016\/j.jep.2012.10.030_bib200","unstructured":"Kharelep, C.P., 2004. Encyclopedia of Indian Medicinal Plants (Regional Western Therapy, Ayurvedic and other Traditional Usage, Botany), Springer-verlag Berlin, Heidelberg, New york, pp. 318\u2013319."},{"key":"10.1016\/j.jep.2012.10.030_bib26","first-page":"13","article-title":"The histological, histomorphometrical and histochemical changes of testicular tissue in the metformin treated and untreated streptozotocin-induced adult diabetic rats","volume":"2","author":"Kianifard","year":"2011","journal-title":"Veterinary Research Forum"},{"key":"10.1016\/j.jep.2012.10.030_bib27","doi-asserted-by":"crossref","first-page":"5751","DOI":"10.1016\/S0021-9258(19)83842-5","article-title":"Superoxide radical inhibits catalase","volume":"257","author":"Kono","year":"1982","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib28","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.1210\/jc.2007-2616","article-title":"Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa","volume":"93","author":"Koppers","year":"2008","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"10.1016\/j.jep.2012.10.030_bib29","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S0167-5699(97)80014-X","article-title":"Mitochondrial control of apoptosis","volume":"18","author":"Kroemer","year":"1997","journal-title":"Immunology Today"},{"key":"10.1016\/j.jep.2012.10.030_bib30","doi-asserted-by":"crossref","first-page":"R1014","DOI":"10.1152\/ajpregu.00124.2004","article-title":"Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology","volume":"287","author":"Li","year":"2004","journal-title":"American Journal of Physiology-Regulatory Integrative and Comparative Physiology"},{"key":"10.1016\/j.jep.2012.10.030_bib31","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin's phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib32","doi-asserted-by":"crossref","first-page":"5715","DOI":"10.1523\/JNEUROSCI.20-15-05715.2000","article-title":"Delayed mitochondrial dysfunction in excitotoxic neuron death: cytochrome c release and a secondary increase in superoxide production","volume":"20","author":"Luetjens","year":"2000","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.jep.2012.10.030_bib33","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.arr.2005.02.005","article-title":"The effects of stress and aging on glutathione metabolism","volume":"4","author":"Maher","year":"2005","journal-title":"Ageing Research Review"},{"key":"10.1016\/j.jep.2012.10.030_bib34","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/0006-2952(73)90407-3","article-title":"Effect of insulin on the metabolism of l-ascorbic acid in animals","volume":"22","author":"Majumder","year":"1972","journal-title":"Biochemistry and Pharmacology"},{"key":"10.1016\/j.jep.2012.10.030_bib35","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","article-title":"Involvement of superoxide anion radical in the auto oxidation of pyrogallol and a constituent assay for superoxide dismutase","volume":"47","author":"Marklund","year":"1974","journal-title":"European Journal of Biochemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib36","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1016\/j.phytochem.2004.08.045","article-title":"Alkaloidal constituents of Mucuna pruriens seeds","volume":"65","author":"Misra","year":"2004","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib37","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0304-4165(79)90289-7","article-title":"Levels of glutathione and glutathione reductase and glutathione-S-transferase activity in rat lung and liver","volume":"582","author":"Moron","year":"1979","journal-title":"Biochimica et Biophysica Acta"},{"key":"10.1016\/j.jep.2012.10.030_bib38","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/35008121","article-title":"Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage","volume":"404","author":"Nishikawa","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.jep.2012.10.030_bib39","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Analytical Biochemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib40","first-page":"1","article-title":"Selected method for the determination of ascorbic acid in animal cells, tissue and fluid","volume":"62","author":"Omaye","year":"1979","journal-title":"Methods in Enzymology"},{"key":"10.1016\/j.jep.2012.10.030_bib41","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF02591100","article-title":"Semen analyses in adolescent diabetic patients","volume":"21","author":"Padron","year":"1984","journal-title":"Acta Diabetologica Latina"},{"key":"10.1016\/j.jep.2012.10.030_bib203","unstructured":"Pant, M.C., Joshi, L.D., 1970. Identification of pharmacologically active substances in the seeds of Mucuna pruriens (Abs). In: Proceedings of Annual Conference of Indian Pharmacological Society. Lucknow, India. Indian Journal of Pharmacology 2, 24."},{"key":"10.1016\/j.jep.2012.10.030_bib42","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/0304-4165(91)90031-B","article-title":"Inhibition of oxidation of hydroxyl radical scavenging agent after alkaline phosphatase treatment of rat liver microsome","volume":"1074","author":"Pantarulo","year":"1991","journal-title":"Biochimica et Biophysica Acta"},{"key":"10.1016\/j.jep.2012.10.030_bib43","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0008-8749(81)90411-1","article-title":"Superoxide anion and hydrogen peroxide production by chemically elicited peritoneal macrophages induced by multiple non-phagocytic stimuli","volume":"59","author":"Pick","year":"1981","journal-title":"Cellular Immunology"},{"key":"10.1016\/j.jep.2012.10.030_bib44","first-page":"31","article-title":"Studies on in vitro antioxidant activities of methanol extract of Mucuna pruriens Fabaceae seeds","volume":"13","author":"Rajeshwar","year":"2005","journal-title":"European Bulletin of Drug Research"},{"key":"10.1016\/j.jep.2012.10.030_bib204","first-page":"236","article-title":"Effect of some indigenous drugs on the sexual behaviour of male rats","volume":"40","author":"Rao","year":"1978","journal-title":"Indian Journal of Pharmacological Sciences"},{"key":"10.1016\/j.jep.2012.10.030_bib45","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/ptr.842","article-title":"The effect of Momordica charantia and Mucunapruriens in experimental diabetes and their effect on key metabolic enzymes involved in carbohydrate metabolism","volume":"163","author":"Rathi","year":"2002","journal-title":"Phytotherapy Research"},{"key":"10.1016\/j.jep.2012.10.030_bib46","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1126\/science.179.4073.588","article-title":"Selenium: biochemical role as a component of glutathione peroxidase","volume":"179","author":"Rotruck","year":"1973","journal-title":"Science"},{"key":"10.1016\/j.jep.2012.10.030_bib205","first-page":"3","article-title":"Role of total alkaloids of Mucucna pruriens bark in spermatogenesis in albino rats","volume":"3","author":"Saksena","year":"1987","journal-title":"Indian Journal of Natural Products"},{"key":"10.1016\/j.jep.2012.10.030_bib47","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/j.1365-2605.2006.00682.x","article-title":"Sexual behavior, sperm quantity and quality after short-term streptozotocin n induced hyperglycemia in rats","volume":"29","author":"Scarano","year":"2006","journal-title":"International Journal of Andrology"},{"key":"10.1016\/j.jep.2012.10.030_bib49","first-page":"228","article-title":"Pharmacological screening of indian medicinal plants","volume":"16","author":"Sharma","year":"1978","journal-title":"Indian Journal of Experimental Biology"},{"key":"10.1016\/j.jep.2012.10.030_bib50","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.reprotox.2007.02.001","article-title":"Early oxidative stress in testis and epididymal sperm in streptozotocin-induced diabetic mice: its progression and genotoxic consequences","volume":"23","author":"Shrilatha","year":"2007","journal-title":"Reproductive Toxicology"},{"key":"10.1016\/j.jep.2012.10.030_bib51","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1093\/ecam\/nem171","article-title":"Mucuna pruriens reduces stress and improves the quality of semen in infertile men","volume":"7","author":"Shukla","year":"2010","journal-title":"Evidence-Based Complimentary and Alternative Medicine"},{"key":"10.1016\/j.jep.2012.10.030_bib52","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1016\/j.fertnstert.2008.09.045","article-title":"Mucuna pruriens improves male fertility by its action on the hypothalamus\u2013pituitary\u2013gonadal axis","volume":"92","author":"Shukla","year":"2009","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.jep.2012.10.030_bib206","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1021\/jf950776x","article-title":"Chemical composition and protein quality of the little known legume, velvet bean (Mucuna pruriens (L.) DC.)","volume":"44","author":"Siddhuraju","year":"1996","journal-title":"Journal Agriculture Food Chemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib53","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1002\/jcb.22337","article-title":"Impact of experimental diabetes and insulin replacement on epididymal secretory products and sperm maturation in albino rats","volume":"108","author":"Singh","year":"2009","journal-title":"Journal of Cellular Biochemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib54","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0003-2697(72)90132-7","article-title":"Colorimetric assay of catalase","volume":"47","author":"Sinha","year":"1972","journal-title":"Analytical Biochemistry"},{"key":"10.1016\/j.jep.2012.10.030_bib55","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0005-2744(69)90280-0","article-title":"Purification and properties of glutathione reductase of human erythrocytes","volume":"185","author":"Staal","year":"1969","journal-title":"Biochimica et Biophysica Acta"},{"key":"10.1016\/j.jep.2012.10.030_bib56","article-title":"Effect of Mucuna pruriens Linn. on sexual behavior and sperm parameters in streptozotocin-induced diabetic male rat","author":"Suresh","year":"2010","journal-title":"Journal Sexual Medicine"},{"key":"10.1016\/j.jep.2012.10.030_bib57","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.jep.2009.01.032","article-title":"Dose- and time-dependent effects of ethanolic extract of Mucuna pruriens Linn. seed on sexual behaviour of normal male rats","volume":"22","author":"Suresh","year":"2009","journal-title":"Journal of Ethno-Pharmacology"},{"key":"10.1016\/j.jep.2012.10.030_bib58","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1365-2605.2008.00949.x","article-title":"Effect of Mucuna pruriens on oxidative stress mediated damage in aged rat sperm","volume":"33","author":"Suresh","year":"2010","journal-title":"International Journal of Andrology"},{"key":"10.1016\/j.jep.2012.10.030_bib60","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.freeradbiomed.2006.12.008","article-title":"Role of mitochondrial reactive oxygen species in hypoxia depended increase in intracellular calcium in pulmonary artery myocytes","volume":"42","author":"Wang","year":"2007","journal-title":"Free Radical Biology and Medicine"},{"key":"10.1016\/j.jep.2012.10.030_bib61","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/S0015-0282(03)00983-X","article-title":"Alterations in mitochondria membrane potential and oxidative stress in infertile men: a prospective observational study","volume":"80","author":"Wang","year":"2003","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.jep.2012.10.030_bib62","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0015-0282(03)00756-8","article-title":"Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertility","volume":"80","author":"Wang","year":"2003","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.jep.2012.10.030_bib63","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1071\/R96109","article-title":"Mitochondrial function and ram sperm fertility","volume":"9","author":"Windsor","year":"1997","journal-title":"Reproduction Fertility and Development"},{"key":"10.1016\/j.jep.2012.10.030_bib64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-1110(83)90014-3","article-title":"An evaluation of the mouse sperm morphology test and other sperm tests in nonhuman mammals. A report of the US Environmental Protection Agency Gene-Tox Program","volume":"115","author":"Wyrobek","year":"1983","journal-title":"Mutation Research"},{"key":"10.1016\/j.jep.2012.10.030_bib65","series-title":"Bio-Statistical Analysis","author":"Zar","year":"1974"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874112007027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874112007027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T15:09:02Z","timestamp":1714489742000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874112007027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":70,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0378874112007027"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2012.10.030","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}