{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:50:38Z","timestamp":1788871838481,"version":"build-2803163510"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"name":"National \u201c12th Five-Year\u201d Science and Technology Support project","award":["2011BAD22B08"],"award-info":[{"award-number":["2011BAD22B08"]}]},{"name":"Special Key Projects for Basic National Science and Technology of China","award":["2008FY110400-2"],"award-info":[{"award-number":["2008FY110400-2"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.jep.2013.03.058","type":"journal-article","created":{"date-parts":[[2013,3,29]],"date-time":"2013-03-29T23:10:03Z","timestamp":1364598603000},"page":"517-524","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Antioxidant and anti-inflammatory activities of the phenolic extracts of Sapium sebiferum (L.) Roxb. leaves"],"prefix":"10.1016","volume":"147","author":[{"given":"Rao","family":"Fu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Ting","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ran","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiu-Lan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2013.03.058_bib1","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1038\/sj.jid.5700340","article-title":"Oxidative stress in the pathogenesis of skin disease","volume":"126","author":"Bickers","year":"2006","journal-title":"The Journal of Investigative Dermatology"},{"key":"10.1016\/j.jep.2013.03.058_bib2","first-page":"016","article-title":"Analgesic and anti-inflammatory effect of extract of Sapium sebiferum leaves on animal model","volume":"6","author":"Bin-xue","year":"2004","journal-title":"Chinese Traditional Patent Medicine"},{"key":"10.1016\/j.jep.2013.03.058_bib3","doi-asserted-by":"crossref","first-page":"3827","DOI":"10.1021\/jf060901c","article-title":"Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside","volume":"54","author":"Breksa","year":"2006","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"10.1016\/j.jep.2013.03.058_bib4","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1046\/j.1468-3083.2003.00751.x","article-title":"Antioxidant activity, lipid peroxidation and skin diseases","volume":"17","author":"Briganti","year":"2003","journal-title":"What's New. Journal of the European Academy of Dermatology and Venereology"},{"key":"10.1016\/j.jep.2013.03.058_bib5","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1016\/j.foodres.2011.03.031","article-title":"Polyphenol contents and in vitro antioxidant activities of lyophilised aqueous extract of kiwifruit (Actinidia deliciosa)","volume":"44","author":"Bursal","year":"2011","journal-title":"Food Research International"},{"key":"10.1016\/j.jep.2013.03.058_bib6","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/BF01966592","article-title":"Modulation of mouse ear edema by cyclooxygenase and lipoxygenase inhibitors and other pharmacologic agents","volume":"17","author":"Carlson","year":"1985","journal-title":"Agents and Actions"},{"key":"10.1016\/j.jep.2013.03.058_bib7","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/j.1749-6632.1992.tb38659.x","article-title":"Oxidant carcinogenesis and antioxidant defense","volume":"663","author":"Cerutti","year":"1992","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1016\/j.jep.2013.03.058_bib8","first-page":"1","article-title":"Inflammation and oxidative stress in carcinogenesis","volume":"3","author":"Cerutti","year":"1991","journal-title":"Cancer Cells"},{"key":"10.1016\/j.jep.2013.03.058_bib9","first-page":"5916","article-title":"Antimicrobial activities of Sapium sebiferum L. belonging to family Euphorbiaceae","volume":"5","author":"Chaudhary","year":"2011","journal-title":"Journal of Medicinal Plants Research"},{"key":"10.1016\/j.jep.2013.03.058_bib10","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jep.2011.04.058","article-title":"In vitro and in vivo antioxidant effects of the ethanolic extract of Swertia chirayita","volume":"136","author":"Chen","year":"2011","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2013.03.058_bib11","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/eji.200425778","article-title":"In vivo quercitrin anti\u2010inflammatory effect involves release of quercetin, which inhibits inflammation through down\u2010regulation of the NF\u2010\u03baB pathway","volume":"35","author":"Comalada","year":"2005","journal-title":"European Journal of Immunology"},{"key":"10.1016\/j.jep.2013.03.058_bib12","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.foodchem.2011.03.090","article-title":"Antioxidant activity of Gardenia jasminoides Ellis fruit extracts","volume":"128","author":"Debnath","year":"2011","journal-title":"Food Chemistry"},{"key":"10.1016\/j.jep.2013.03.058_bib13","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/1099-1263(200007\/08)20:4<335::AID-JAT698>3.0.CO;2-L","article-title":"Epidermal cytokines in murine cutaneous irritant responses","volume":"20","author":"Effendy","year":"2000","journal-title":"Journal of Applied Toxicology"},{"key":"10.1016\/j.jep.2013.03.058_bib14","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1007\/s00403-012-1254-0","article-title":"The association of oxidative stress and disease activity in seborrheic dermatitis","volume":"304","author":"Emre","year":"2012","journal-title":"Archives of Dermatological Research"},{"key":"10.1016\/j.jep.2013.03.058_bib15","series-title":"CRC Handbook of Methods for Oxygen Radical Research","author":"Greenwald","year":"1985"},{"key":"10.1016\/j.jep.2013.03.058_bib16","article-title":"Chemical composition study of Chinese tallow tree leaves","volume":"27","author":"Guangxiong","year":"1996","journal-title":"Chinese Herbal Medicine"},{"key":"10.1016\/j.jep.2013.03.058_bib17","doi-asserted-by":"crossref","DOI":"10.1155\/2007\/45673","volume":"2007","author":"H\u00e4m\u00e4l\u00e4inen","year":"2007","journal-title":"Mediators of Inflammation"},{"key":"10.1016\/j.jep.2013.03.058_bib18","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.bbrc.2006.07.079","article-title":"Inhibition of the TPA-induced cutaneous inflammation and hyperplasia by EC-SOD","volume":"348","author":"Ha","year":"2006","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.jep.2013.03.058_bib19","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1021\/np50104a019","article-title":"Antihypertensive activity of 6-O-galloyl-d-glucose, a phenolic glycoside from Sapium sebiferum","volume":"57","author":"Hsu","year":"1994","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2013.03.058_bib20","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.jep.2010.06.029","article-title":"Hepatoprotective and antioxidant effects of the methanolic extract from Halenia elliptica","volume":"131","author":"Huang","year":"2010","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2013.03.058_bib21","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1159\/000136485","article-title":"Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite","volume":"11","author":"Jollow","year":"1974","journal-title":"Pharmacology"},{"key":"10.1016\/j.jep.2013.03.058_bib22","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ijpharm.2011.02.002","article-title":"Comparison of in vitro antioxidant activities and bioactive components of green tea extracts by different extraction methods","volume":"408","author":"Jun","year":"2011","journal-title":"International Journal of Pharmaceutics"},{"key":"10.1016\/j.jep.2013.03.058_bib23","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF01128975","article-title":"Methyl gallate, methyl-3,4,5-trihydroxybenzoate, is a potent and highly specific inhibitor of herpes simplex virus in vitro. I. Purification and characterization of methyl gallate from Sapium sebiferum","volume":"8","author":"Kane","year":"1988","journal-title":"Bioscience Reports"},{"key":"10.1016\/j.jep.2013.03.058_bib24","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1021\/np50057a037","article-title":"Additional biologically active constituents of the Chinese tallow tree (Sapium sebiferum)","volume":"51","author":"Liu","year":"1988","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2013.03.058_bib25","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2174\/1568010054526386","article-title":"Oxidative stress in allergic and inflammatory skin diseases","author":"Okayama","year":"2005","journal-title":"Current Drug Targets. Inflammation and Allergy 4"},{"key":"10.1016\/j.jep.2013.03.058_bib26","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0009-8981(99)00246-6","article-title":"A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1)","volume":"293","author":"Peskin","year":"2000","journal-title":"Clinica Chimica Acta; International Journal of Clinical Chemistry"},{"key":"10.1016\/j.jep.2013.03.058_bib27","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.jep.2011.09.012","article-title":"Effectiveness of Vernonia scorpioides ethanolic extract against skin inflammatory processes","volume":"138","author":"Rauh","year":"2011","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2013.03.058_bib28","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1211\/jpp.58.9.0014","article-title":"Anti\u2010inflammatory, analgesic and anti\u2010oedematous effects of Lafoensia pacari extract and ellagic acid","volume":"58","author":"Rogerio","year":"2006","journal-title":"Journal of Pharmacy and Pharmacology"},{"key":"10.1016\/j.jep.2013.03.058_bib29","first-page":"1213","article-title":"Study of phenolic constituents from Chinese tallow leaves","volume":"30","author":"Runhui","year":"2005","journal-title":"China Journal of Chinese Materia Medica"},{"key":"10.1016\/j.jep.2013.03.058_bib30","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1365-2222.1990.tb03137.x","article-title":"Pathogenesis of eczema","volume":"20","author":"Sampson","year":"1990","journal-title":"Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology"},{"key":"10.1016\/j.jep.2013.03.058_bib31","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1365-4632.2004.02222.x","article-title":"Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis","volume":"43","author":"Sander","year":"2004","journal-title":"International Journal of Dermatology"},{"key":"10.1016\/j.jep.2013.03.058_bib32","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1078\/0940-2993-00260","article-title":"Anti-inflammatory effect of rutin on rat paw oedema, and on neutrophils chemotaxis and degranulation","volume":"54","author":"Selloum","year":"2003","journal-title":"Experimental and Toxicologic Pathology"},{"key":"10.1016\/j.jep.2013.03.058_bib33","doi-asserted-by":"crossref","first-page":"6102","DOI":"10.1021\/jf1004836","article-title":"Antioxidant and anti-inflammatory activities of polyphenolics from Southeastern U.S. range blackberry cultivars","volume":"58","author":"Srivastava","year":"2010","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"10.1016\/j.jep.2013.03.058_bib34","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1016\/j.fct.2011.07.042","article-title":"Evaluation to the antioxidant activity of total flavonoids extract from persimmon (Diospyros kaki L.) leaves","volume":"49","author":"Sun","year":"2011","journal-title":"Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association"},{"key":"10.1016\/j.jep.2013.03.058_bib35","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1016\/S0024-3205(03)00145-0","article-title":"Oxidative stress and altered antioxidant defenses in children with acute exacerbation of atopic dermatitis","volume":"72","author":"Tsukahara","year":"2003","journal-title":"Life Sciences"},{"key":"10.1016\/j.jep.2013.03.058_bib36","first-page":"4","article-title":"The use of Sapium trees for the control of schistosomiasis","volume":"7","author":"Yong-Feng","year":"2011","journal-title":"Wetland Science & Management"},{"key":"10.1016\/j.jep.2013.03.058_bib37","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.ifset.2007.06.006","article-title":"Antioxidant, immunomodulatory and anti-breast cancer activities of phenolic extract from pine (Pinus massoniana Lamb) bark","volume":"9","author":"Yu","year":"2008","journal-title":"Innovative Food Science & Emerging Technologies"},{"key":"10.1016\/j.jep.2013.03.058_bib38","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.freeradbiomed.2009.06.033","article-title":"Oxidative stress in the pathogenesis of psoriasis","volume":"47","author":"Zhou","year":"2009","journal-title":"Free radical Biology & Medicine"}],"updated-by":[{"DOI":"10.1016\/j.jep.2013.04.042","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2013,6,21]],"date-time":"2013-06-21T00:00:00Z","timestamp":1371772800000}}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874113002146?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874113002146?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T22:16:01Z","timestamp":1741904161000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874113002146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0378874113002146"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2013.03.058","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antioxidant and anti-inflammatory activities of the phenolic extracts of Sapium sebiferum (L.) Roxb. leaves","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2013.03.058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ireland Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}